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... Rab (Ras-related proteins in brain) GTPases are a family of proteins encoded by a group of at least 60 genes. This must be considered as a minimum estimate, as a small part of the genome still remains to be sequence [1]. Rab GTPases cycle between active and inactive states, GTP-bound or GDP-bound fo ...
... Rab (Ras-related proteins in brain) GTPases are a family of proteins encoded by a group of at least 60 genes. This must be considered as a minimum estimate, as a small part of the genome still remains to be sequence [1]. Rab GTPases cycle between active and inactive states, GTP-bound or GDP-bound fo ...
Tomato SlSnRK1 Protein Interacts with and
... SlSnRK1 protein attenuates geminivirus infection by interacting with and phosphorylating the bC1 protein. ...
... SlSnRK1 protein attenuates geminivirus infection by interacting with and phosphorylating the bC1 protein. ...
Mitochondria, the cell cycle, and the origin of sex via a syncytial
... Many variations on this theme exist, for example, the presence or absence of the nuclear envelope in closed and open mitosis (Raikov 1994) or other variants such as cell senescence or specialization where the cells enter into a stage where they cease dividing (Blagosklonny 2011). Meiosis, also calle ...
... Many variations on this theme exist, for example, the presence or absence of the nuclear envelope in closed and open mitosis (Raikov 1994) or other variants such as cell senescence or specialization where the cells enter into a stage where they cease dividing (Blagosklonny 2011). Meiosis, also calle ...
Rusnak_Rosenzweig_2000 - Vanderbilt University School of Medicine
... domain topology that generates the substrate binding groove and active site cavity. The phosphoesterase motif observed in the eukaryotic Ser/ Thr PPases is conserved in a number of other enzymes involved in the hydrolysis of phosphate esters (15), including the purple acid phosphatases (PAPs) (21) a ...
... domain topology that generates the substrate binding groove and active site cavity. The phosphoesterase motif observed in the eukaryotic Ser/ Thr PPases is conserved in a number of other enzymes involved in the hydrolysis of phosphate esters (15), including the purple acid phosphatases (PAPs) (21) a ...
Post-transcriptional control of gene expression: a genome
... most transcripts, usually occurs by changes in the phosphorylation state of translation initiation factors and by adjusting the number of available ribosomes. Transcript-specific regulation, by contrast, modulates the translation of a distinct group of mRNAs and is mediated by a large diversity of m ...
... most transcripts, usually occurs by changes in the phosphorylation state of translation initiation factors and by adjusting the number of available ribosomes. Transcript-specific regulation, by contrast, modulates the translation of a distinct group of mRNAs and is mediated by a large diversity of m ...
1-3 flagellum - Instituto de Higiene
... reminiscent of the mammalian protein recoverin [13], another EF-hand Ca + 2-binding protein from retinal rod cells that associates with the plasma membrane, when intracellular Ca + 2 levels rise. Membrane association of recoverin leads to inhibition of rhodopsin kinase and thus serves to transmit ch ...
... reminiscent of the mammalian protein recoverin [13], another EF-hand Ca + 2-binding protein from retinal rod cells that associates with the plasma membrane, when intracellular Ca + 2 levels rise. Membrane association of recoverin leads to inhibition of rhodopsin kinase and thus serves to transmit ch ...
Protein Posttranslational Modifications: The Chemistry of Proteome
... rium Pseudomonas aeruginosa exhibits more than 60 such pathways.[6] The enzymes dedicated to protein phosphorylation are among the largest class of PTM enzymes. This superfamily of protein kinases have been termed the kinome, with over 500 members in the human kinome.[7] If these acted on average on ...
... rium Pseudomonas aeruginosa exhibits more than 60 such pathways.[6] The enzymes dedicated to protein phosphorylation are among the largest class of PTM enzymes. This superfamily of protein kinases have been termed the kinome, with over 500 members in the human kinome.[7] If these acted on average on ...
Mechanosensitive Channels:
... located with in the membrane, while MscS has a large portion of its structure in the cytoplasm. It is important to note that the first 26 amino acids of the N-terminal end of MscS did not get resolved during the structural determination. This difference is also noted in the fact that MscS is a homoh ...
... located with in the membrane, while MscS has a large portion of its structure in the cytoplasm. It is important to note that the first 26 amino acids of the N-terminal end of MscS did not get resolved during the structural determination. This difference is also noted in the fact that MscS is a homoh ...
Sequence elements of the fusion peptide of human respiratory
... HRSV F shares structural features with the F protein of other paramyxoviruses, despite limited sequence identity. Thus, all F proteins have three main hydrophobic regions: one, at the N terminus, which acts as the signal peptide for translocation into the ER; another region, which is the membrane an ...
... HRSV F shares structural features with the F protein of other paramyxoviruses, despite limited sequence identity. Thus, all F proteins have three main hydrophobic regions: one, at the N terminus, which acts as the signal peptide for translocation into the ER; another region, which is the membrane an ...
msb145697-sup-0001-Supp_Info
... and , responding to only Climitation and only A-limitation, respectively. While the C- and A- sector proteins belong only to the and respectively, the “multi-purpose” S-sector proteins belong to both lists. B An illustrative mechanism generating the expression pattern of an S-sector protein: the cor ...
... and , responding to only Climitation and only A-limitation, respectively. While the C- and A- sector proteins belong only to the and respectively, the “multi-purpose” S-sector proteins belong to both lists. B An illustrative mechanism generating the expression pattern of an S-sector protein: the cor ...
Acid – base balance
... All the known low molecular weight and water soluble biosynthetic intermediates possess groups that are almost completely ionised at neutral pH’ ...
... All the known low molecular weight and water soluble biosynthetic intermediates possess groups that are almost completely ionised at neutral pH’ ...
NIH Public Access
... PG minimal medium [23] was prepared with the following modifications. First, a desired total volume of 50 mM Na2HPO4, 50 mM KH2PO4, and 5 mM Na2SO4 was mixed and 500-mL aliquots were placed into 2-L baffled-bottom flasks, which were subjected to autoclave sterilization. Immediately before inoculatio ...
... PG minimal medium [23] was prepared with the following modifications. First, a desired total volume of 50 mM Na2HPO4, 50 mM KH2PO4, and 5 mM Na2SO4 was mixed and 500-mL aliquots were placed into 2-L baffled-bottom flasks, which were subjected to autoclave sterilization. Immediately before inoculatio ...
Muscular System Overview of Muscle Tissues • Types of Muscle
... o Note that during a regular muscle contraction, all myosin heads would cycle, but not all are bound or disconnected at the same time. Physiology of Skeletal Muscle Fibers o For a skeletal muscle to contract: It must be activated (i.e., stimulated by a nerve ending) causing a change in the membran ...
... o Note that during a regular muscle contraction, all myosin heads would cycle, but not all are bound or disconnected at the same time. Physiology of Skeletal Muscle Fibers o For a skeletal muscle to contract: It must be activated (i.e., stimulated by a nerve ending) causing a change in the membran ...
Retrograde Signaling in the Development and Modification of
... Synapses. Physiol. Rev. 78: 143–170, 1998.—Retrograde signaling from the postsynaptic cell to the presynaptic neuron is essential for the development, maintenance, and activity-dependent modification of synaptic connections. This review covers various forms of retrograde interactions at developing a ...
... Synapses. Physiol. Rev. 78: 143–170, 1998.—Retrograde signaling from the postsynaptic cell to the presynaptic neuron is essential for the development, maintenance, and activity-dependent modification of synaptic connections. This review covers various forms of retrograde interactions at developing a ...
The Unfolded Protein Response Is Triggered by a Plant Viral
... dpi. The plants were fully and systemically infected at 9 dpi, although we extracted RNA from the inoculated leaves. Zero dpi represents samples that were harvested just before plants were inoculated with PVXGFP. Given that the genome sequence for N. benthamiana is incompletely annotated, primers we ...
... dpi. The plants were fully and systemically infected at 9 dpi, although we extracted RNA from the inoculated leaves. Zero dpi represents samples that were harvested just before plants were inoculated with PVXGFP. Given that the genome sequence for N. benthamiana is incompletely annotated, primers we ...
Document
... form of ATP. However, mitochondria also have roles outside of energy regulation: they are involved in calcium signaling and intermediary metabolism, and they regulate the extrinsic apoptotic pathway following cell insult. Recent studies show that mitochondria are implicated in many diseases includin ...
... form of ATP. However, mitochondria also have roles outside of energy regulation: they are involved in calcium signaling and intermediary metabolism, and they regulate the extrinsic apoptotic pathway following cell insult. Recent studies show that mitochondria are implicated in many diseases includin ...
Symmetry, asymmetry, and the cell cycle in plants: known knowns
... and Dhonukshe, 2013). Two sister cells can acquire divergent fates as a result of extrinsic factors, such as interactions with neighbouring cells and environmental signals, or of intrinsic cell factors that are inherited unequally. The latter type of asymmetric cell divisions require that organelles ...
... and Dhonukshe, 2013). Two sister cells can acquire divergent fates as a result of extrinsic factors, such as interactions with neighbouring cells and environmental signals, or of intrinsic cell factors that are inherited unequally. The latter type of asymmetric cell divisions require that organelles ...
Intercellular signalling and the multiplication of prokaryotes
... Tissue cultures of cells taken from higher, differentiated organisms normally need complex (and mainly polypeptidic or proteinaceous) extracellular growth factors for successful cell division (and even survival (Raff, 1992)). These factors are nowadays usually referred to as cytokines (Callard & ...
... Tissue cultures of cells taken from higher, differentiated organisms normally need complex (and mainly polypeptidic or proteinaceous) extracellular growth factors for successful cell division (and even survival (Raff, 1992)). These factors are nowadays usually referred to as cytokines (Callard & ...
Neural control of the circulation - Advances in Physiology Education
... throughout the body. Venules and capillaries, which lack smooth muscle, are not directly innervated by sympathetic nerves. Norepinephrine released from the sympathetic nerve terminals binds to ␣1- or ␣2-adrenergic receptors located on vascular smooth muscle cells to increase intracellular Ca2⫹ eithe ...
... throughout the body. Venules and capillaries, which lack smooth muscle, are not directly innervated by sympathetic nerves. Norepinephrine released from the sympathetic nerve terminals binds to ␣1- or ␣2-adrenergic receptors located on vascular smooth muscle cells to increase intracellular Ca2⫹ eithe ...
r-Gir - Microbiology
... The germ tube of the dimorphic human pathogen C. albicans has been the focus of my interests for many years. We have, over the years, worked with this fungus at the cellular, physiological and molecular levels in order to understand the mechanism that regulates the yeast to hyphal transition and the ...
... The germ tube of the dimorphic human pathogen C. albicans has been the focus of my interests for many years. We have, over the years, worked with this fungus at the cellular, physiological and molecular levels in order to understand the mechanism that regulates the yeast to hyphal transition and the ...
ISMB2006-Docking7
... – Divide ligand input files – Some programs have specific parallel implementations (PVM or MPI implementations,…) ...
... – Divide ligand input files – Some programs have specific parallel implementations (PVM or MPI implementations,…) ...
2015 – PKc-theta is a novel sc35 splicing factor regulator in
... processes (12). In addition to its crucial function as an alternative splicing regulator, SC35 also participates in transcriptional elongation, RNA stability, mRNA transport, and translation (13, 14). Furthermore, human SC35 binds exonic splicing enhancers under splicing conditions (15). SC35 is ass ...
... processes (12). In addition to its crucial function as an alternative splicing regulator, SC35 also participates in transcriptional elongation, RNA stability, mRNA transport, and translation (13, 14). Furthermore, human SC35 binds exonic splicing enhancers under splicing conditions (15). SC35 is ass ...
A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants
... pathogens, the envelope is the site of first contact with the host and where major pathogenicity determinants such as adhesins and toxin secretion systems assemble [1–3]. Uniquely bacterial in origin, cell envelope building blocks are also recognized by host innate immune receptors as signs of invas ...
... pathogens, the envelope is the site of first contact with the host and where major pathogenicity determinants such as adhesins and toxin secretion systems assemble [1–3]. Uniquely bacterial in origin, cell envelope building blocks are also recognized by host innate immune receptors as signs of invas ...
Chemoinformatics in Molecular Docking and Drug
... – Divide ligand input files – Some programs have specific parallel implementations (PVM or MPI implementations,…) ...
... – Divide ligand input files – Some programs have specific parallel implementations (PVM or MPI implementations,…) ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.