Hypothesized Deficiency of Guanine
... purines are involved in synaptic transmission; for example, the exchange of GDP and GTP and the hydrolysis of GTP while bound to heterotrimeric G proteins anchored to the membrane are critical steps in the regulation of the initiation and duration of several second messenger cascades.26 Recent work ...
... purines are involved in synaptic transmission; for example, the exchange of GDP and GTP and the hydrolysis of GTP while bound to heterotrimeric G proteins anchored to the membrane are critical steps in the regulation of the initiation and duration of several second messenger cascades.26 Recent work ...
Dynamics of Lipid Transfer by Phosphatidylinositol Transfer Proteins
... implicated in essential cellular processes, but the activity of none has been demonstrated in intact cells. Among these, phosphatidylinositol transfer proteins (PITP) are of particular interest as they can bind to and transfer phosphatidylinositol (PtdIns) – the precursor of important signalling mol ...
... implicated in essential cellular processes, but the activity of none has been demonstrated in intact cells. Among these, phosphatidylinositol transfer proteins (PITP) are of particular interest as they can bind to and transfer phosphatidylinositol (PtdIns) – the precursor of important signalling mol ...
Lactic acid excretion by Streptococcus mutans
... broth at -20 "C. The strain was checked regularly according to the criteria of Hardie & Bowden (1976). Bacteria were grown as batch cultures at 37 OC in T Y E growth medium as described previously (Dashper & Reynolds, 1990, 1992). Cells were harvested at mid-exponential phase by centrifugation (1500 ...
... broth at -20 "C. The strain was checked regularly according to the criteria of Hardie & Bowden (1976). Bacteria were grown as batch cultures at 37 OC in T Y E growth medium as described previously (Dashper & Reynolds, 1990, 1992). Cells were harvested at mid-exponential phase by centrifugation (1500 ...
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... consequence of a stress perturbation is an alteration in the metabolic behavior of the cell, leading to a cascade of molecular and biochemical events that facilitate a new steady state to be reached. Depending on the development stage of the plant or type of stress applied, the phenotypical output c ...
... consequence of a stress perturbation is an alteration in the metabolic behavior of the cell, leading to a cascade of molecular and biochemical events that facilitate a new steady state to be reached. Depending on the development stage of the plant or type of stress applied, the phenotypical output c ...
The bit used for relationship between smell and taste
... glomeruli such that each glomerulus receives input primarily from olfactory receptor neurons that express the same olfactory receptor. Glomeruli are also permeated by ...
... glomeruli such that each glomerulus receives input primarily from olfactory receptor neurons that express the same olfactory receptor. Glomeruli are also permeated by ...
Molecular Evolution and Structure of a
... calcium binding (Witke et al. 1993; Janssen et al. 1996). These two domains are connected by the rod domain. This domain is formed by triple-helical repeats or so-called spectrin repeats, where each repeat contains approximately 106 amino acid residues (Djinovic-Carugo et al. 1999). The rod domain o ...
... calcium binding (Witke et al. 1993; Janssen et al. 1996). These two domains are connected by the rod domain. This domain is formed by triple-helical repeats or so-called spectrin repeats, where each repeat contains approximately 106 amino acid residues (Djinovic-Carugo et al. 1999). The rod domain o ...
jxb.oxfordjournals.org
... AtGRF gene targets in 35S:miR396a and 35S:miR396b plants were all decreased (Supplementary Fig. S1J), indicating that miR396 negatively regulates the cell proliferation in leaves by repressing the expression of AtGRF genes, consistent with reported results (Liu et al., 2009; Rodriguez et al., 2010). ...
... AtGRF gene targets in 35S:miR396a and 35S:miR396b plants were all decreased (Supplementary Fig. S1J), indicating that miR396 negatively regulates the cell proliferation in leaves by repressing the expression of AtGRF genes, consistent with reported results (Liu et al., 2009; Rodriguez et al., 2010). ...
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... or dFmr1 heterozygotes, which appear to have normal NMJ and similar FMRP has been strongly implicated39. Finally, disruption of this mechanumbers of synaptic boutons to wild-type larvae, the trans-heterozygote nism, via the loss of FMRP in fragile X syndrome, would signify the (l(2)k00208/+;dFmr13/+ ...
... or dFmr1 heterozygotes, which appear to have normal NMJ and similar FMRP has been strongly implicated39. Finally, disruption of this mechanumbers of synaptic boutons to wild-type larvae, the trans-heterozygote nism, via the loss of FMRP in fragile X syndrome, would signify the (l(2)k00208/+;dFmr13/+ ...
HYPOTHALAMUS
... Plate 29 shows the relationship of troph-hormone producing cells to fenestrated capillaries in the anterior pituitary. The magno- and parvocellular cell groups producing the hypothalamic hormones receive a variety of stimuli from different parts of the brain, primarily within the hypothalamus, but ...
... Plate 29 shows the relationship of troph-hormone producing cells to fenestrated capillaries in the anterior pituitary. The magno- and parvocellular cell groups producing the hypothalamic hormones receive a variety of stimuli from different parts of the brain, primarily within the hypothalamus, but ...
The Sympathetic Nerve—An Integrative Interface between Two
... and secondary lymphoid organs are not only extensively hardwired by noradrenergic nerve terminals but also the immune cells, thereby the immune system is tuned by norepinephrine (NE) released locally from nonsynaptic varicosities or circulating epinephrine secreted by the adrenal medulla. Therefore, ...
... and secondary lymphoid organs are not only extensively hardwired by noradrenergic nerve terminals but also the immune cells, thereby the immune system is tuned by norepinephrine (NE) released locally from nonsynaptic varicosities or circulating epinephrine secreted by the adrenal medulla. Therefore, ...
The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to
... Fig. 1. Rhodopsin is targeted to primary cilia of kidney epithelial IMCD3 cells in a FIP3-dependent manner. (A) IMCD3 cells transiently expressing Rh– GFP–VxPx were transfected with control siRNA, fixed, stained with antibody against acetylated (Ac) tubulin and analyzed by confocal microscopy. Two c ...
... Fig. 1. Rhodopsin is targeted to primary cilia of kidney epithelial IMCD3 cells in a FIP3-dependent manner. (A) IMCD3 cells transiently expressing Rh– GFP–VxPx were transfected with control siRNA, fixed, stained with antibody against acetylated (Ac) tubulin and analyzed by confocal microscopy. Two c ...
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... zebrafish and shown to be expressed specifically in macrophages (Thisse et al., 2001), a pattern reminiscent of the haematopoietic restriction of human DOCK2 (Nishihara et al., 1999). We therefore focussed our attention on the identification of the other two sub-family members, dock1 and dock5. Usin ...
... zebrafish and shown to be expressed specifically in macrophages (Thisse et al., 2001), a pattern reminiscent of the haematopoietic restriction of human DOCK2 (Nishihara et al., 1999). We therefore focussed our attention on the identification of the other two sub-family members, dock1 and dock5. Usin ...
Smell Prism - Systems Neuroscience Course, MEDS 371, Univ
... hundreds of olfactory receptors (OR). Olfactory sensory neurons (OSN) have dendrites with cilia containing a G-protiencoupled OR and axons that communicate to the olfactory bulb. OSN can regenerate, giving them an unusual ability to recover from injury. OSN located in separate regions use 4 subfamil ...
... hundreds of olfactory receptors (OR). Olfactory sensory neurons (OSN) have dendrites with cilia containing a G-protiencoupled OR and axons that communicate to the olfactory bulb. OSN can regenerate, giving them an unusual ability to recover from injury. OSN located in separate regions use 4 subfamil ...
Everything you wanted to know about small RNA but were afraid to ask
... the microRNA-target relationships and their functional consequences. For example, there are 11 distinct members of the let-7 microRNA family in humans, differing from each other by a few bases at most.50 The short length of microRNAs and their binding sites within target genes should give them the o ...
... the microRNA-target relationships and their functional consequences. For example, there are 11 distinct members of the let-7 microRNA family in humans, differing from each other by a few bases at most.50 The short length of microRNAs and their binding sites within target genes should give them the o ...
Nature Cell Biol. 6
... co-precipitate mAVO3 and vice versa. Together, this suggests that mTOR forms two distinct complexes: one containing raptor and mLST8, and the other containing mAVO3 and mLST8. On the basis of the obvious similarity to their yeast counterparts, we refer to these two complexes as mTORC1 and mTORC2, re ...
... co-precipitate mAVO3 and vice versa. Together, this suggests that mTOR forms two distinct complexes: one containing raptor and mLST8, and the other containing mAVO3 and mLST8. On the basis of the obvious similarity to their yeast counterparts, we refer to these two complexes as mTORC1 and mTORC2, re ...
ABSTRACT Title of Document:
... I would like to thank my advisor Volker Briken for all of his support and guidance. Working in his lab has been an inspiring example of how an advisor can maintain a position of authority while treating students with respect and care. I would like to thank my wonderful lab members for their help, ad ...
... I would like to thank my advisor Volker Briken for all of his support and guidance. Working in his lab has been an inspiring example of how an advisor can maintain a position of authority while treating students with respect and care. I would like to thank my wonderful lab members for their help, ad ...
Questions for Endocrine Bingo
... 28. Storage and release of hormones-NO PRODUCTION Gland that is an extension of the hypothalamus ...
... 28. Storage and release of hormones-NO PRODUCTION Gland that is an extension of the hypothalamus ...
HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins
... cell lysates (Figure 1b, upper left panel, lanes 2–8). The molecular weight of the different Vpr-CAT fusion proteins ranged between approximately 29 kDa and 35 kDa. Analysis of viral lysates indicates that Vpr-CAT fusion proteins R1-42CAT, R1-80CAT, R1-88CAT and R1488CAT are packaged into virions at ...
... cell lysates (Figure 1b, upper left panel, lanes 2–8). The molecular weight of the different Vpr-CAT fusion proteins ranged between approximately 29 kDa and 35 kDa. Analysis of viral lysates indicates that Vpr-CAT fusion proteins R1-42CAT, R1-80CAT, R1-88CAT and R1488CAT are packaged into virions at ...
BRNO UNIVERSITY OF TECHNOLOGY FACULTY OF
... the major constituent of living cells and participate in almost every biological process in all organisms. Therefore, a comprehensive protein analysis provides a unique global perspective on how these molecules interact and cooperate to create and maintain a working biological system.3,8 ...
... the major constituent of living cells and participate in almost every biological process in all organisms. Therefore, a comprehensive protein analysis provides a unique global perspective on how these molecules interact and cooperate to create and maintain a working biological system.3,8 ...
Effect of Growth at Sub-lethal Concentrations of Kanamycin on the
... acid. The samples were then centrifuged in microfuge tubes at 16,000 x g for 5 minutes (Eppendorf 5415 D microfuge). Glucuronic acid assay. The glucuronic acid assay was carried out based on procedures described by Bitter and Muir (2). After centrifugation, 0.5 mL of each of the purified capsular sa ...
... acid. The samples were then centrifuged in microfuge tubes at 16,000 x g for 5 minutes (Eppendorf 5415 D microfuge). Glucuronic acid assay. The glucuronic acid assay was carried out based on procedures described by Bitter and Muir (2). After centrifugation, 0.5 mL of each of the purified capsular sa ...
Pulmonary immune cells in health and disease: lymphocytes
... human T-cell subset<; are known. In most T-cells, TCR is constituted by two distinct transmembrane heterodimers formed by « and ~ binding chains [14]; more recently, it has been demonstrated that a small subset of T-cells expresses y/o heterodimers [ 15]. Using WT31 MoAb that recognizes the w~ TCR, ...
... human T-cell subset<; are known. In most T-cells, TCR is constituted by two distinct transmembrane heterodimers formed by « and ~ binding chains [14]; more recently, it has been demonstrated that a small subset of T-cells expresses y/o heterodimers [ 15]. Using WT31 MoAb that recognizes the w~ TCR, ...
November 2012 - An error occurred.
... building material over the centuries results from a combination of desirable factors, including surprising strength for a material so light in weight.” Since the black locust waterproofs its sapwood with flavonoids, turning it into rot-resisting heartwood, “The scientists used this process as an ins ...
... building material over the centuries results from a combination of desirable factors, including surprising strength for a material so light in weight.” Since the black locust waterproofs its sapwood with flavonoids, turning it into rot-resisting heartwood, “The scientists used this process as an ins ...
Exploring the Complement Interaction Network
... structures and to down-regulate the response after eliminating the threat. This complex and complicated task is fulfilled by a tailored and carefully balanced network of various soluble and membrane-bound proteins, which react with each other, with pathogenic proteins, or with surface structures (Wa ...
... structures and to down-regulate the response after eliminating the threat. This complex and complicated task is fulfilled by a tailored and carefully balanced network of various soluble and membrane-bound proteins, which react with each other, with pathogenic proteins, or with surface structures (Wa ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.