Biochemistry and Molecular Biology of
... significant homology with yeast (Saccharomyces cerevisiae) cytochrome c peroxidase (Mittler and Zilinskas, 1992). The genes for cytosolic APX (apx1) of pea and Arabidopsis have 10 exons and nine introns (Fig. 1). The first intron is located in the 5⬘-UTR, and this may have an effect on transcription ...
... significant homology with yeast (Saccharomyces cerevisiae) cytochrome c peroxidase (Mittler and Zilinskas, 1992). The genes for cytosolic APX (apx1) of pea and Arabidopsis have 10 exons and nine introns (Fig. 1). The first intron is located in the 5⬘-UTR, and this may have an effect on transcription ...
An Enhancer Trap Screen for Ecdysone
... the apical contractile belt in this process is supported by the observation that cytochalasins (agents that disrupt actin filaments) reversibly inhibit leg elongation in culture (Fristrom and Fristrom 1975). For cells to respond to the force exerted by the apical contractile belt, their attachments ...
... the apical contractile belt in this process is supported by the observation that cytochalasins (agents that disrupt actin filaments) reversibly inhibit leg elongation in culture (Fristrom and Fristrom 1975). For cells to respond to the force exerted by the apical contractile belt, their attachments ...
Mediated Activation of the Cholinergic Anti
... homeostasis and acupuncture has been recently shown to regulate inflammatory responses through the activation of the cholinergic anti-inflammatory pathway. Understanding immune system innervation can provide modern medicine with new tools to prevent, as well as treat immune-mediated disorders and di ...
... homeostasis and acupuncture has been recently shown to regulate inflammatory responses through the activation of the cholinergic anti-inflammatory pathway. Understanding immune system innervation can provide modern medicine with new tools to prevent, as well as treat immune-mediated disorders and di ...
Constitutive heat shock protein 70 (HSC70) expression in rainbow
... The 70-kDa family of heat shock proteins plays an important role as molecular chaperones in unstressed and stressed cells. The constitutive member of the 70 family (hsc70) is crucial for the chaperoning function of unstressed cells, whereas the inducible form (hsp70) is important for allowing cells ...
... The 70-kDa family of heat shock proteins plays an important role as molecular chaperones in unstressed and stressed cells. The constitutive member of the 70 family (hsc70) is crucial for the chaperoning function of unstressed cells, whereas the inducible form (hsp70) is important for allowing cells ...
Nervous and Endocrine Systems
... with certain receptors can receive the signals. Think of your nervous system being like cable television. A physical wire connects your television to the cable provider. Similarly, your nervous system sends its signals through a physical network of specialized tissues. The nervous and endocrine sy ...
... with certain receptors can receive the signals. Think of your nervous system being like cable television. A physical wire connects your television to the cable provider. Similarly, your nervous system sends its signals through a physical network of specialized tissues. The nervous and endocrine sy ...
PDF - Department of Molecular Biology
... agree with a prior study showing that mutations preventing the interaction of mouse Synaptojanin and Endophilin caused only modest endocytic defects (Mani et al., 2007). Collectively, these results support the notion that interactions between Endophilin and Synaptojanin do not play an essential role ...
... agree with a prior study showing that mutations preventing the interaction of mouse Synaptojanin and Endophilin caused only modest endocytic defects (Mani et al., 2007). Collectively, these results support the notion that interactions between Endophilin and Synaptojanin do not play an essential role ...
Scholarly Interest Report
... Our primary interest is in the cellular interactions and molecular pathways that control the development of the nervous system. In particular, we are interested in role of cell-cell communication in the organization of tissue boundaries in the developing eye, and in the determination of cell number ...
... Our primary interest is in the cellular interactions and molecular pathways that control the development of the nervous system. In particular, we are interested in role of cell-cell communication in the organization of tissue boundaries in the developing eye, and in the determination of cell number ...
Medicinal Chemistry of Antifungal Agents
... Eukaryotes, like mammalian cells, with many similar biochemical structures: • DNA is organized into chromosomes within the nucleus • Distinct cytoplasmic organelles: endoplasmic reticulum, Golgi apparatus, mitochondria, and storage vacuoles. • Cell membrane This homology to mammalian cells also exte ...
... Eukaryotes, like mammalian cells, with many similar biochemical structures: • DNA is organized into chromosomes within the nucleus • Distinct cytoplasmic organelles: endoplasmic reticulum, Golgi apparatus, mitochondria, and storage vacuoles. • Cell membrane This homology to mammalian cells also exte ...
Synapse Jeopardy
... • A special molecule on a dendrite that tastes each specific neurotransmitter. ...
... • A special molecule on a dendrite that tastes each specific neurotransmitter. ...
Antagonists and agonists at the glycine site of the NMDA receptor for
... normal rats. In comparison, the open-channel blocker MK-801 is very unselective because it also interferes with the activity (firing rates) of non-nociceptive neurons in normal animals. The antihyperalgesic activity of GV196771A is not accompanied by development of tolerance, which is in line with t ...
... normal rats. In comparison, the open-channel blocker MK-801 is very unselective because it also interferes with the activity (firing rates) of non-nociceptive neurons in normal animals. The antihyperalgesic activity of GV196771A is not accompanied by development of tolerance, which is in line with t ...
COMMUNICATION Redefining the phenotype of Heat shock protein 90
... AUY922 (structures in Supplementary Fig. 1a and b), and Cterminal modulators SM253 and SM258 (structures in Supplementary Fig. 1c and d). Pulling down Hsp90 from cell lysates required tagged versions of these inhibitors, thus PEG-Biotin-tagged SM253 and SM258 (SM253-Tag and SM258-Tag, Supplementary ...
... AUY922 (structures in Supplementary Fig. 1a and b), and Cterminal modulators SM253 and SM258 (structures in Supplementary Fig. 1c and d). Pulling down Hsp90 from cell lysates required tagged versions of these inhibitors, thus PEG-Biotin-tagged SM253 and SM258 (SM253-Tag and SM258-Tag, Supplementary ...
(Hsp90) inhibitors
... AUY922 (structures in Supplementary Fig. 1a and b), and Cterminal modulators SM253 and SM258 (structures in Supplementary Fig. 1c and d). Pulling down Hsp90 from cell lysates required tagged versions of these inhibitors, thus PEG-Biotin-tagged SM253 and SM258 (SM253-Tag and SM258-Tag, Supplementary ...
... AUY922 (structures in Supplementary Fig. 1a and b), and Cterminal modulators SM253 and SM258 (structures in Supplementary Fig. 1c and d). Pulling down Hsp90 from cell lysates required tagged versions of these inhibitors, thus PEG-Biotin-tagged SM253 and SM258 (SM253-Tag and SM258-Tag, Supplementary ...
Nonlysosomal Vesicles (Acidosomes) Are Involved
... (1) to follow the time course of the pH changes in phagosomes (2-5) and endosomes ( l, 4, 6-8) of various cells suggest that the pH of a vesicle or vacuole that derives from the cell surface often becomes acid before such an organelle fuses with lysosomes. Thus the mechanism for the initial acidific ...
... (1) to follow the time course of the pH changes in phagosomes (2-5) and endosomes ( l, 4, 6-8) of various cells suggest that the pH of a vesicle or vacuole that derives from the cell surface often becomes acid before such an organelle fuses with lysosomes. Thus the mechanism for the initial acidific ...
1 - Purdue Department of Biological Sciences
... Fig. 2 a Transverse section from the mature zone of the zinnia stem, showing the arrangement of leaf-trace and stem bundles. Numbered bundles represent the 12 vascular bundles in the zinnia stem (Dahiya et al. 2005). Recently, branched bundles are not numbered and can be recognized by comparatively ...
... Fig. 2 a Transverse section from the mature zone of the zinnia stem, showing the arrangement of leaf-trace and stem bundles. Numbered bundles represent the 12 vascular bundles in the zinnia stem (Dahiya et al. 2005). Recently, branched bundles are not numbered and can be recognized by comparatively ...
HS Life Science Crosswalk
... enzyme action, growth and repair of body parts, regulation of cell division and differentiation) Also listed as a compliment to HS-LS1-1 (Strand 3) 2.B.d. * Explain how an error in the DNA molecule (mutation) can be transferred during replication (Strand 3) 2.D.c. Recognize that new heritable charac ...
... enzyme action, growth and repair of body parts, regulation of cell division and differentiation) Also listed as a compliment to HS-LS1-1 (Strand 3) 2.B.d. * Explain how an error in the DNA molecule (mutation) can be transferred during replication (Strand 3) 2.D.c. Recognize that new heritable charac ...
Tracheary Element Differentiation
... and auxin to increase secondary growth in the stem and compared tissues undergoing primary growth with those undergoing secondary growth as a means of identifying genes specifically involved in secondary xylem formation (59, 88). The many different cell types in the Arabidopsis stem add complexity to ...
... and auxin to increase secondary growth in the stem and compared tissues undergoing primary growth with those undergoing secondary growth as a means of identifying genes specifically involved in secondary xylem formation (59, 88). The many different cell types in the Arabidopsis stem add complexity to ...
Fission yeast Tor2 promotes cell growth and represses cell
... The fission yeast Schizosaccharomyces pombe is an excellent model system in which to study the coordination of cell growth and cell differentiation. In the presence of nutrients, fission yeast cells grow and divide; in the absence of nutrients, they stop growing and undergo cell differentiation. The ...
... The fission yeast Schizosaccharomyces pombe is an excellent model system in which to study the coordination of cell growth and cell differentiation. In the presence of nutrients, fission yeast cells grow and divide; in the absence of nutrients, they stop growing and undergo cell differentiation. The ...
- Wiley Online Library
... a halogen lamp and are excited into a singlet state (1RB) with around 10-8 s lifetime. The excited molecules transfer energy to molecular oxygen (3O2) present in the proximity, leading to the generation of singlet oxygen (1O2) and initiate a cascade of energy transfer reactions and intermediates, wh ...
... a halogen lamp and are excited into a singlet state (1RB) with around 10-8 s lifetime. The excited molecules transfer energy to molecular oxygen (3O2) present in the proximity, leading to the generation of singlet oxygen (1O2) and initiate a cascade of energy transfer reactions and intermediates, wh ...
The Bordetella pertussis adenylate cyclase toxin binds to T cells via
... induce down-regulation of the putative receptor, although no variation in the levels of either the 7 integrin or the TCR–CD3 complex was observed (Fig. S1 A). Together, the data suggest that CyaA binds to T cells via LFA-1. The fact that CyaA binding was enhanced in activated T cells (Fig. 1 E) sug ...
... induce down-regulation of the putative receptor, although no variation in the levels of either the 7 integrin or the TCR–CD3 complex was observed (Fig. S1 A). Together, the data suggest that CyaA binds to T cells via LFA-1. The fact that CyaA binding was enhanced in activated T cells (Fig. 1 E) sug ...
Allosteric Interactions after 50Years
... widely used as a measure of cooperativity. 11 An interesting functional connection to feedback-inhibited enzymes can be made from early hemoglobin experiments by Wyman on the effect of urea. 12 The notion of quaternary constraint was unknown at the time, but addition of urea led to an increase in th ...
... widely used as a measure of cooperativity. 11 An interesting functional connection to feedback-inhibited enzymes can be made from early hemoglobin experiments by Wyman on the effect of urea. 12 The notion of quaternary constraint was unknown at the time, but addition of urea led to an increase in th ...
Print - Circulation Research
... cell types make many extracellular macromolecules. Although it seems likely that fibroblasts produce some, if not most, of the collagen synthesized in mature hearts it should be stressed that the myocardium is a heterogeneous structure containing vascular endothelium, vascular smooth muscle, nerves, ...
... cell types make many extracellular macromolecules. Although it seems likely that fibroblasts produce some, if not most, of the collagen synthesized in mature hearts it should be stressed that the myocardium is a heterogeneous structure containing vascular endothelium, vascular smooth muscle, nerves, ...
C. elegans as a model organism to investigate
... misregulation beyond the DA system. Nevertheless, mammalian models may not recapitulate all PD pathological impairments (Fleming and Chesselet, 2006); moreover, these models have limitations and are expensive. In this regard, despite their lack of evolutionary complexity, invertebrate model organism ...
... misregulation beyond the DA system. Nevertheless, mammalian models may not recapitulate all PD pathological impairments (Fleming and Chesselet, 2006); moreover, these models have limitations and are expensive. In this regard, despite their lack of evolutionary complexity, invertebrate model organism ...
Sample & Assay Technologies QIAgenes E. coli
... IPTG (~1 mM) or using autoinduction media overcomes the inhibitory effect of the lysozyme protein present in the cell. Please note that the QIAgenes expression constructs contain the T7lac promotor, which provides an additional level of regulation (Figure 5). Using the T7lac promoter in combination ...
... IPTG (~1 mM) or using autoinduction media overcomes the inhibitory effect of the lysozyme protein present in the cell. Please note that the QIAgenes expression constructs contain the T7lac promotor, which provides an additional level of regulation (Figure 5). Using the T7lac promoter in combination ...
PDF
... Originally, the regions where spindle fibers attach to each chromosome during cell division were named “centromere” (Darlington, 1936) and “kinetochore” (Schrader, 1936) and were long thought redundant. Nowadays, functional centromeres are generally recognized as specialized chromosome regions involv ...
... Originally, the regions where spindle fibers attach to each chromosome during cell division were named “centromere” (Darlington, 1936) and “kinetochore” (Schrader, 1936) and were long thought redundant. Nowadays, functional centromeres are generally recognized as specialized chromosome regions involv ...
REVIEWS
... FBI-1 is a cellular POZ-domain-containing protein that binds to the HIV-1 long-terminal repeat and associates with the HIV-1 transactivator protein Tat 66. FBI-1 has been found to partially colocalize with Tat and its cellular cofactor, P-TEFb, at nuclear speckles67. In addition, the nucleosome-bind ...
... FBI-1 is a cellular POZ-domain-containing protein that binds to the HIV-1 long-terminal repeat and associates with the HIV-1 transactivator protein Tat 66. FBI-1 has been found to partially colocalize with Tat and its cellular cofactor, P-TEFb, at nuclear speckles67. In addition, the nucleosome-bind ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.