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My Life with Dicty
My Life with Dicty

... the next 24 hours my attention was totally focused on the developing cells as they aggregated, formed slugs, and culminated into fruiting bodies. I was enamored but did not realize for several years that it would be a life long affair. The following year a paper by Francois Jacob and Jacques Monod w ...
G α 12/13 regulate epiboly by inhibiting E
G α 12/13 regulate epiboly by inhibiting E

... defect was observed in E-cadherin–deficient embryos, with cells bulging and detaching from the embryonic surface (Babb and Marrs, 2004; Kane et al., 2005; McFarland et al., 2005; Shimizu et al., 2005). E-cadherin is a plasma membrane glycoprotein that is indirectly linked to the actin cytoskeleton t ...
Negative feedback control of the autoimmune
Negative feedback control of the autoimmune

... below the detection level throughout the course of i.n. peptide treatment, irrespective of the addition of rhIL-2 (not depicted). These results support the findings of previous studies showing that IL-2 reverses the anergy of peptideinduced IL-10 T reg cells from mice treated with 10 doses of i.n. p ...
spatial control of cell expansion by the plant cytoskeleton
spatial control of cell expansion by the plant cytoskeleton

... by University of California - San Diego on 10/18/05. For personal use only. ...
When cells get stressed: an integrative view of cellular senescence
When cells get stressed: an integrative view of cellular senescence

... the latter were true, then telomeric DNA could no longer be viewed as a counting device that advances autonomously at its own rate, but should rather be viewed as a cellular structure that responds to stress. In fact, it has been reported in the past that the telomeres of some cells shorten more qui ...
Role for Rab7 in maturation of late autophagic vacuoles
Role for Rab7 in maturation of late autophagic vacuoles

... corresponded to autophagic vacuoles surrounding late endosomal or lysosomal vesicles. Our experiments with quantitative electron microscopy showed that Rab7 was not ...
Glucose-Regulated Anaplerosis and Cataplerosis in
Glucose-Regulated Anaplerosis and Cataplerosis in

... Cell culture and incubation conditions. INS-1 cells were seeded in 21 cm2 petri dishes (1.4  106 cells/dish) and grown in regular RPMI medium containing 10% heat-inactivated fetal calf serum as described previously (24). When cells reached 80% confluence after ~7 days, they were washed twice with p ...
When cells get stressed: an integrative view of cellular
When cells get stressed: an integrative view of cellular

... the latter were true, then telomeric DNA could no longer be viewed as a counting device that advances autonomously at its own rate, but should rather be viewed as a cellular structure that responds to stress. In fact, it has been reported in the past that the telomeres of some cells shorten more qui ...
Interaction of the Two Frontal Eye Fields Before Saccade Onset
Interaction of the Two Frontal Eye Fields Before Saccade Onset

... visuomotor, motor-related, and fixation cells. Because individual studies usually focus on a single structure, the capabilities of this structure tend to be singled out to the point where one could conclude hastily that no other center really is needed for shifting gaze. Yet there are several centra ...
Functions and Mechanisms of Fibroblast Growth Factor (FGF
Functions and Mechanisms of Fibroblast Growth Factor (FGF

... presumably more than 70 FGFR/FGF combinations are generated by four FGFRs and 22 FGF ligands, respectively; alternative mRNA splicing increases the FGFR repertoire from four to seven proteins [2,3]. Moreover, from the possible FGFR/FGF combinations, human cells may utilize more than one at the same ...
On the Morphology of the Drosophila Heart
On the Morphology of the Drosophila Heart

... Abstract: The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to na ...
Chap 3 PP
Chap 3 PP

... • The name means mouth first and refers to the formation of the mouth from the embryonic blastophore. The anus forms secondarily in protostomes • Coelomate –animals that forms its coelom by schizocoely in ...
Boundary Representation Deformation in Parametric Solid Modeling
Boundary Representation Deformation in Parametric Solid Modeling

... would indicate that e 1 was mapped to e92 ; in the latter case the placement of the hole was also affected by the orientation of the mapped edge e92 (which is opposite to that of e91 with respect to face f93 ). In both cases the assumption of continuity is violated, even though the correct continuou ...
The functional cobalamin (vitamin B12)–intrinsic factor receptor is a
The functional cobalamin (vitamin B12)–intrinsic factor receptor is a

... Endocytosis of human IF-cobalamin in cubilin-transfected, AMN-myc– transfected, cubilin/AMN-myc–double transfected, and mock-transfected CHO cells was analyzed as described for other ligands.12,31 Briefly, triplicates of cells grown to confluence in 24-well plates (0.08-0.13 mg protein/well) were in ...
Science Jeopardy - Broward County Public Schools
Science Jeopardy - Broward County Public Schools

... (1) Save a duplicate of this template. (2) Enter all answers and questions in the normal view. (view/normal) (3) Change the category headings in the normal view (view/normal) (4) View as a slideshow. (5) Use the home red button after each question. ...
FVIII-specific human chimeric antigen receptor T
FVIII-specific human chimeric antigen receptor T

... induction (ITI), a process that is expensive, time-consuming and not entirely effective. The development of effective tolerogenic therapies to prevent, as well as reverse, inhibitor formation is clearly needed. Recently, regulatory T cells (Tregs) have been proposed as a potential clinical therapy f ...
PDF
PDF

... oocyte-nurse cell complexes. egh and brn do not appear to be required for regulating germ cell division Wild-type (WT) oogenesis is described in detail in Fig. 1. Since previous results indicated that brn is required in the germline for formation of the follicular epithelium, we characterized marker ...
AUTOPHAGIC VACUOLES PRODUCED IN VITRO
AUTOPHAGIC VACUOLES PRODUCED IN VITRO

... washed and inverted over a thin rim of paraffin on glass slides so that chambers were made approximately the depth of a No. cover slip. The chambers were filled with fresh medium with or without ...
C H E M I S T R Y
C H E M I S T R Y

... • Clot formation possible • Xanthrochromic supernatent • – RBCs must have been in CSF @ 2+ hours • - D-dimer, fibrin degradation product from hemorrhage site • Microscopic presence of erythrophages, or siderophages, Hemosiderin granules ...
Neural differentiation from embryonic stem cells in vitro: An overview
Neural differentiation from embryonic stem cells in vitro: An overview

... reported the differentiation of ESCs into a range of embryonic tissues. These compelling results were done either by stimulating the cells with particular molecules or by simulating the environmental cues of the early embryo. Importantly, these differentiated cells can then be used in regenerative ...
Interplay between SCARECROW, GA and LIKE
Interplay between SCARECROW, GA and LIKE

... Regulated cell division is critical for the development of multi-cellular organisms. In the Arabidopsis root, SCARECROW (SCR) is required for the first cell division, but represses the subsequent, longitudinal asymmetric cell divisions that generate the two cell types of the ground tissue – cortex a ...
MECHANISMS, CHALLENGES AND OPPORTUNITIES IN STROKE
MECHANISMS, CHALLENGES AND OPPORTUNITIES IN STROKE

... underperfused brain areas. With MRI, there is often a volume mismatch between tissue showing reduced water molecule diffusion (a signature for cell swelling and ischaemic tissue) and a larger area of compromised tissue perfusion early after stroke onset. The difference reflects potentially salvageab ...
Role of Adenosine in Response to Vascular Inflammation
Role of Adenosine in Response to Vascular Inflammation

... 1990’s and selective agonists and antagonists became available, rapid progress was made in pinpointing the identity and function of adenosine receptor subtypes on cardiac and vascular tissues. During that time it was also realized that 1 or more adenosine receptors are found on all cell types and th ...
Epiblast and primitive-streak origins of the endoderm in
Epiblast and primitive-streak origins of the endoderm in

... Injections of the parastreak epiblast For injections of the parastreak epiblast, embryos at stages 3a/b and 3c (n=15) were cultured dorsal side upwards in Spratt culture (Spratt, 1947), modified as described by Schoenwolf (Schoenwolf, 1988). The epiblast was injected lateral to the rostral end of th ...
Making parallel lines meet
Making parallel lines meet

... as pom-pom2) have morphological phenotypes associated with aberrant cortical microtubules,14,16 some of which can be ameliorated by transgenic expression of an animal microtubule-associated protein (MAP4) that is absent from plants. Taken together, this evidence shows that CSI1, although discovered ...
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Tissue engineering



Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.
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