Hallmarks of epithelial to mesenchymal transition are detectable in
... the fact that the pathogenesis of CD-related fibrosis is only poorly understood. Here, we demonstrate the presence of EMT-associated events in fibrotic areas of colonic tissue specimens derived from CD patients. A characteristic feature of EMT is the translocation of β-catenin from the cytosol, whe ...
... the fact that the pathogenesis of CD-related fibrosis is only poorly understood. Here, we demonstrate the presence of EMT-associated events in fibrotic areas of colonic tissue specimens derived from CD patients. A characteristic feature of EMT is the translocation of β-catenin from the cytosol, whe ...
Characterization of a gastrointestinal tract microscale cell culture
... control, ran at a flow rate of 4 mL/h without re-circulation, and only one experiment could be performed at a time. Choi et al. (2004a) developed a physiologically based, multicompartment, in vitro perfusion system with re-circulation that could be used to study intestinal drug absorption and first ...
... control, ran at a flow rate of 4 mL/h without re-circulation, and only one experiment could be performed at a time. Choi et al. (2004a) developed a physiologically based, multicompartment, in vitro perfusion system with re-circulation that could be used to study intestinal drug absorption and first ...
pig-1_final 121812
... PAR-4 and STRD-1 function in the same pathway as PIG-1 and promote other PIG-1dependent asymmetries: The observation that the strd-1(rr91); par-4(it57ts) double mutant died during embryogenesis, even at the permissive temperature for par-4(it57ts) (KIM et al. 2010; NARBONNE et al. 2010), precluded u ...
... PAR-4 and STRD-1 function in the same pathway as PIG-1 and promote other PIG-1dependent asymmetries: The observation that the strd-1(rr91); par-4(it57ts) double mutant died during embryogenesis, even at the permissive temperature for par-4(it57ts) (KIM et al. 2010; NARBONNE et al. 2010), precluded u ...
Precipitation of calcium, magnesium, strontium and barium in tissues
... Morphologies and Locations of Crystals in Mature Plants Grown in the Field Prismatic crystals were observed in cells associated with fibre cells in phyllodes of all four species collected from mature plants grown in the field, and all prismatic crystals were birefringent (Fig. 1). There were also ot ...
... Morphologies and Locations of Crystals in Mature Plants Grown in the Field Prismatic crystals were observed in cells associated with fibre cells in phyllodes of all four species collected from mature plants grown in the field, and all prismatic crystals were birefringent (Fig. 1). There were also ot ...
PDF - Oxford Academic - Oxford University Press
... Chitosan [b-(1–4)-2-amino-2-deoxy-D-glucose] is a natural polycationic polysaccharide derived from the exoskeleton of insects, the shells of crustaceans and fungal cell walls. It is the deacetylated form of chitin and is made up of N-acetyl-D-glucosamine and D-glucosamine. CH is found to possess sev ...
... Chitosan [b-(1–4)-2-amino-2-deoxy-D-glucose] is a natural polycationic polysaccharide derived from the exoskeleton of insects, the shells of crustaceans and fungal cell walls. It is the deacetylated form of chitin and is made up of N-acetyl-D-glucosamine and D-glucosamine. CH is found to possess sev ...
Transverse Viscoelastic Extension in Nitella
... occurred at pH 3.5 (Fig. 1). Acid-stimulated creep was not inhibited by boiling in either methanol or water for 15 min, indicating that a physical rather than an enzymic mechanism is involved. Figure 2 illustrates the relationship between the stimulation obtained with acid and the in vivo growth rat ...
... occurred at pH 3.5 (Fig. 1). Acid-stimulated creep was not inhibited by boiling in either methanol or water for 15 min, indicating that a physical rather than an enzymic mechanism is involved. Figure 2 illustrates the relationship between the stimulation obtained with acid and the in vivo growth rat ...
Molecular regulation of the diatom cell cycle
... cycle phase from vegetative division to spore formation or sexual reproduction (Smetacek, 2012). The major limiting nutrients of primary production in the oceans are nitrogen, phosphorus, iron, and silicon (Falkowski et al., 1998). As a major constituent of amino acids and nucleic acids, nitrogen is ...
... cycle phase from vegetative division to spore formation or sexual reproduction (Smetacek, 2012). The major limiting nutrients of primary production in the oceans are nitrogen, phosphorus, iron, and silicon (Falkowski et al., 1998). As a major constituent of amino acids and nucleic acids, nitrogen is ...
Calcium-Containing Organelles Display Unique Reactivity to
... 300 msec pulse, n 5 11 cells) caused a transient rise in [Ca]i, which initially started in CCOs (see the insert amplification of the first part of the graph) and was larger in the nucleus than in cytoplasm or the CCOs, and a slower recovery to baseline in the latter than in former two compartments. ...
... 300 msec pulse, n 5 11 cells) caused a transient rise in [Ca]i, which initially started in CCOs (see the insert amplification of the first part of the graph) and was larger in the nucleus than in cytoplasm or the CCOs, and a slower recovery to baseline in the latter than in former two compartments. ...
The Putative Arabidopsis Arp2/3 Complex
... the leading edge of migrating animal cells (Welch et al., 1997a; Morrell et al., 1999; Schaerer-Brodbeck and Riezman, 2000a, 2000b; Higgs and Pollard, 2001). As a multifunctional organizer, the cellular roles of the Arp2/3 complex involve the control of actin polymerization nucleation for many cell ...
... the leading edge of migrating animal cells (Welch et al., 1997a; Morrell et al., 1999; Schaerer-Brodbeck and Riezman, 2000a, 2000b; Higgs and Pollard, 2001). As a multifunctional organizer, the cellular roles of the Arp2/3 complex involve the control of actin polymerization nucleation for many cell ...
Cilia Review Article - Eastern Virginia Medical School
... Work with C. elegans provided early clues that the gene products for PKD1 and PKD2 might also be involved with cilia structure and/or function. During the examination of mutations that affect mating behavior in C. elegans, Barr et al. (1999, 2001) identified worm homologs of PKD1 as lov-1 (for locat ...
... Work with C. elegans provided early clues that the gene products for PKD1 and PKD2 might also be involved with cilia structure and/or function. During the examination of mutations that affect mating behavior in C. elegans, Barr et al. (1999, 2001) identified worm homologs of PKD1 as lov-1 (for locat ...
Nervous Tissue - Essex County College Faculty Web Server
... • Neurons are electrically excitable due to the voltage difference across their membrane • Communicate with 2 types of electric signals – action potentials that can travel long distances – graded potentials that are local membrane changes only ...
... • Neurons are electrically excitable due to the voltage difference across their membrane • Communicate with 2 types of electric signals – action potentials that can travel long distances – graded potentials that are local membrane changes only ...
Antibody Selection for Immobilizing Living Bacteria
... bacterial cell microarrays is the detachment of bacterial cells from the substrate causing sensor failure. Reliable, facile, and efficient immobilization methods are critical to the success of bacterial cell microarrays. Such immobilization methods will also have wide applications in biomedical fiel ...
... bacterial cell microarrays is the detachment of bacterial cells from the substrate causing sensor failure. Reliable, facile, and efficient immobilization methods are critical to the success of bacterial cell microarrays. Such immobilization methods will also have wide applications in biomedical fiel ...
An Early Tobacco Mosaic Virus-Induced Oxidative Burst in Tobacco
... transients that are catalase insensitive. In contrast, catalase has been shown to dissipate H2O2 transients generated in the apoplast by amine oxidase-like activity after addition of l-Arg and other amines (Allan and Fluhr, 1997). The elicitation of ROS by the TMV virions was found to be insensitive ...
... transients that are catalase insensitive. In contrast, catalase has been shown to dissipate H2O2 transients generated in the apoplast by amine oxidase-like activity after addition of l-Arg and other amines (Allan and Fluhr, 1997). The elicitation of ROS by the TMV virions was found to be insensitive ...
HIV-1 Evolves into a Nonsyncytium-Inducing Virus upon Prolonged
... axes). This observation is consistent with the previous results in SupT1 cells (Fig. 2). As expected, infection and replication of the wild-type LAI virus was strongly inhibited by SDF-1 (Figs. 3A and 3C), but a very similar pattern was observed for LAI env (Figs. 3B and 3D). In a control experiment ...
... axes). This observation is consistent with the previous results in SupT1 cells (Fig. 2). As expected, infection and replication of the wild-type LAI virus was strongly inhibited by SDF-1 (Figs. 3A and 3C), but a very similar pattern was observed for LAI env (Figs. 3B and 3D). In a control experiment ...
comparative study of extracellular fibrils on the ectodermal layer in
... observed similar fibrils in the flank region of neurulae of several different species. He also observed that there are many fewer fibrils in R. palustris embryos than in A. maculatum embryos. Johnson, Silver & Kelley (1979) also failed to observe discrete fibrillar structures on the inner aspect of ...
... observed similar fibrils in the flank region of neurulae of several different species. He also observed that there are many fewer fibrils in R. palustris embryos than in A. maculatum embryos. Johnson, Silver & Kelley (1979) also failed to observe discrete fibrillar structures on the inner aspect of ...
Identification of genes controlling germ cell migration and embryonic
... a transformation of part of the PMG into a more hindgut-like tissue. In these mutants, the PMG intercellular gaps fail to form and germ cells are rendered helpless to reach their destination in the mesoderm (Jaglarz and Howard, 1995; Reuter, 1994; Warrior, 1994). Once across the gut wall, the germ c ...
... a transformation of part of the PMG into a more hindgut-like tissue. In these mutants, the PMG intercellular gaps fail to form and germ cells are rendered helpless to reach their destination in the mesoderm (Jaglarz and Howard, 1995; Reuter, 1994; Warrior, 1994). Once across the gut wall, the germ c ...
Dynamin as a mover and pincher during cell migration and invasion
... with lipids, actin and several new binding partners are providing some insight into its lamellipodial localization and support this notion. Dynamin and actin dynamics Several seminal studies provided the initial impetus for pursuing a relationship between dynamin and the actin cytoskeleton. Initiall ...
... with lipids, actin and several new binding partners are providing some insight into its lamellipodial localization and support this notion. Dynamin and actin dynamics Several seminal studies provided the initial impetus for pursuing a relationship between dynamin and the actin cytoskeleton. Initiall ...
NETosis: how vital is it?
... unclear if these mechanisms also occur in PMNs or if they are required for liberation of DNA into the cytoplasm prior to NET release. Certainly, PMNs are likely to employ unique mechanisms of nuclear envelope breakdown. For example, elastase relocation to the nucleus is a prerequisite for NET releas ...
... unclear if these mechanisms also occur in PMNs or if they are required for liberation of DNA into the cytoplasm prior to NET release. Certainly, PMNs are likely to employ unique mechanisms of nuclear envelope breakdown. For example, elastase relocation to the nucleus is a prerequisite for NET releas ...
Roles of ion channels and transporters in guard cell signal
... outwardly-rectifying, or weakly rectifying (Fig. 2). The inward K+ channels KAT1, KAT2, AKT1, the outward K+ channel GORK, the K+ channel AKT2/3, whose rectification properties are dependent on its phosphorylation status [30], and the subunit AtKC1, which forms a heteromeric channel with KAT1 or AKT1 ...
... outwardly-rectifying, or weakly rectifying (Fig. 2). The inward K+ channels KAT1, KAT2, AKT1, the outward K+ channel GORK, the K+ channel AKT2/3, whose rectification properties are dependent on its phosphorylation status [30], and the subunit AtKC1, which forms a heteromeric channel with KAT1 or AKT1 ...
To read this - MHE Research Foundation
... accounts of how MHE has affected their children and families and how the disease continues to represent a major medical and personal burden for thousands of patients in this country alone. They stressed the importance of the Conference format with multiple disciplines coming together to forge a cohe ...
... accounts of how MHE has affected their children and families and how the disease continues to represent a major medical and personal burden for thousands of patients in this country alone. They stressed the importance of the Conference format with multiple disciplines coming together to forge a cohe ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.