Slam and germ cell migration - Development
... midgut, we analyzed the development of the midgut and the gonadal mesoderm in mutant embryos. In situ hybridization with RACE, an enzyme expressed in the posterior midgut primordium, reveals a delay in the transition from an epithelium to a mesenchyme in mutant embryos. At stage 11, when in wild-typ ...
... midgut, we analyzed the development of the midgut and the gonadal mesoderm in mutant embryos. In situ hybridization with RACE, an enzyme expressed in the posterior midgut primordium, reveals a delay in the transition from an epithelium to a mesenchyme in mutant embryos. At stage 11, when in wild-typ ...
Integration of the olfactory code across dendritic
... note that this measure of tuning curve distinctiveness likely represents a lower bound, as we were only able to test ten odors in these experiments as a result of photobleaching of the claws. Nevertheless, even within these constraints, it was clear that the dominant feature of the results was the d ...
... note that this measure of tuning curve distinctiveness likely represents a lower bound, as we were only able to test ten odors in these experiments as a result of photobleaching of the claws. Nevertheless, even within these constraints, it was clear that the dominant feature of the results was the d ...
PLGA-Alendronate Conjugate as a New Biomaterial
... A number of drugs are effective for the treatment of bone tumours, but their systemic delivery is inevitably associated with significant side effects and lack of targeting. Thereby, targeting specific biochemical patterns inside bone cancer areas may theoretically provide a mean to improve the effic ...
... A number of drugs are effective for the treatment of bone tumours, but their systemic delivery is inevitably associated with significant side effects and lack of targeting. Thereby, targeting specific biochemical patterns inside bone cancer areas may theoretically provide a mean to improve the effic ...
Signal Perception and Transduction: The Origin of
... two phosphorylated receptor monomers may separate and phosphorylate other inactive receptor monomers or other downstream proteins. Phosphorylation of proteins initiating protein kinase cascades would result in further amplification of the signal. ...
... two phosphorylated receptor monomers may separate and phosphorylate other inactive receptor monomers or other downstream proteins. Phosphorylation of proteins initiating protein kinase cascades would result in further amplification of the signal. ...
Manuscrit en préparation (soumission prévue à Int - HAL
... to inhibition of topoisomerase II and to the production of oxygen-reactive species [21, 22]. Among polyunsaturated fatty acids, DHA, with its 6 double-bonds, is very prone to oxidation. The increased membrane unsaturation index consequently would provide more abundant targets for oxygen-reactive spe ...
... to inhibition of topoisomerase II and to the production of oxygen-reactive species [21, 22]. Among polyunsaturated fatty acids, DHA, with its 6 double-bonds, is very prone to oxidation. The increased membrane unsaturation index consequently would provide more abundant targets for oxygen-reactive spe ...
Growth-modulating molecules are associated with invading
... proteoglycan (CSPG) in the lesion site of a subset of cases, which correlated with the presence of infiltrating Schwann cells (Bruce et al., 2000). However, no data have been presented regarding the spatiotemporal pattern of collagen IV, laminin or fibronectin after SCI. We, therefore, performed an ...
... proteoglycan (CSPG) in the lesion site of a subset of cases, which correlated with the presence of infiltrating Schwann cells (Bruce et al., 2000). However, no data have been presented regarding the spatiotemporal pattern of collagen IV, laminin or fibronectin after SCI. We, therefore, performed an ...
AMPK regulates ER morphology and function in
... morphological changes whose mechanisms and relevance are unknown. We found that the GTPase DRP1, a key regulator of mitochondrial fission, is an ER resident regulating ER morphology in stressed -cells. Inhibition of DRP1 activity using a GTP hydrolysis-defective mutant (Ad-K38A) attenuated fatty ac ...
... morphological changes whose mechanisms and relevance are unknown. We found that the GTPase DRP1, a key regulator of mitochondrial fission, is an ER resident regulating ER morphology in stressed -cells. Inhibition of DRP1 activity using a GTP hydrolysis-defective mutant (Ad-K38A) attenuated fatty ac ...
Phosphatidylcholine traffic to the vacuole
... phospholipids were resuspended by vortex mixing with SDC and the mixture was passed 5-8 times through a Lipex Extruder (Lipex Biomembranes, Vancouver, BC, Canada) equipped with 0.1 µm filters to produce a solution of vesicles with 1 mM total phospholipid. Phospholipid preparations were made fresh fo ...
... phospholipids were resuspended by vortex mixing with SDC and the mixture was passed 5-8 times through a Lipex Extruder (Lipex Biomembranes, Vancouver, BC, Canada) equipped with 0.1 µm filters to produce a solution of vesicles with 1 mM total phospholipid. Phospholipid preparations were made fresh fo ...
Expression and function of cell adhesion molecules during neural
... types. NC cell-cell and cell-matrix interactions are an essential part of the migration ...
... types. NC cell-cell and cell-matrix interactions are an essential part of the migration ...
pdf
... autochthonous carbon. However, even in a given type of system, most studies have examined very few parameters (typically heterotrophic bacterial production and loss to grazers) and have either been limited to a single day/night cycle or based on two to four samplings per 24 h. Thus, in reality, the ...
... autochthonous carbon. However, even in a given type of system, most studies have examined very few parameters (typically heterotrophic bacterial production and loss to grazers) and have either been limited to a single day/night cycle or based on two to four samplings per 24 h. Thus, in reality, the ...
cells
... specimens. Only a single plane of focus is illuminated; out-of-focus fluorescence above and below the plane is subtracted by a computer. A sharp image results, as seen in stained nervous tissue (top), where nerve cells are green, support cells are red, and regions of overlap are yellow. A standard f ...
... specimens. Only a single plane of focus is illuminated; out-of-focus fluorescence above and below the plane is subtracted by a computer. A sharp image results, as seen in stained nervous tissue (top), where nerve cells are green, support cells are red, and regions of overlap are yellow. A standard f ...
Apoptotic cell clearance: basic biology and therapeutic potential
... For example, in inflamed adipose tissue, dying adipocytes seem to be engulfed by multiple macrophages that form ‘crown-like structures’ around a single adipocyte and ingest smaller fragments of the dying cell6. This has also been observed during the clearance of dying cells by fibroblasts in the abs ...
... For example, in inflamed adipose tissue, dying adipocytes seem to be engulfed by multiple macrophages that form ‘crown-like structures’ around a single adipocyte and ingest smaller fragments of the dying cell6. This has also been observed during the clearance of dying cells by fibroblasts in the abs ...
Inhibition of virulence factor expression and swarming differentiation
... protease, haemolysin and ¯agellin during swarm-cell differentiation in P. mirabilis has been reported. To investigate the effects of p-nitrophenylglycerol (PNPG), a potent antiswarming agent, on the various swarming-associated traits of P. mirabilis and to elucidate the relationships among them, P. ...
... protease, haemolysin and ¯agellin during swarm-cell differentiation in P. mirabilis has been reported. To investigate the effects of p-nitrophenylglycerol (PNPG), a potent antiswarming agent, on the various swarming-associated traits of P. mirabilis and to elucidate the relationships among them, P. ...
A Role for the Basal Forebrain Cholinergic System in Estrogen
... Copyright © 2003 Society for Neuroscience 0270-6474/03/234479-12$15.00/0 ...
... Copyright © 2003 Society for Neuroscience 0270-6474/03/234479-12$15.00/0 ...
The control of sexual identity in the Drosophila
... when XY germ cells are present in females (as discussed above), indicating that Sxl mutant XX germ cells are masculinized. Indeed, male-specific gene expression is observed in XX germ cells that lack Sxl (Staab et al., 1996; Wei et al., 1994), and Sxl functions to promote female germ cell developmen ...
... when XY germ cells are present in females (as discussed above), indicating that Sxl mutant XX germ cells are masculinized. Indeed, male-specific gene expression is observed in XX germ cells that lack Sxl (Staab et al., 1996; Wei et al., 1994), and Sxl functions to promote female germ cell developmen ...
Tracheary Element Differentiation
... data analysis, a point illustrated by the observation that the expression of more than 5000 genes, around 20% of the genome, is altered during stem development (28). However, detailed bioinformatic analysis has identified candidates for many aspects of xylem differentiation, particularly SCW formatio ...
... data analysis, a point illustrated by the observation that the expression of more than 5000 genes, around 20% of the genome, is altered during stem development (28). However, detailed bioinformatic analysis has identified candidates for many aspects of xylem differentiation, particularly SCW formatio ...
Functional Utrastructure of Genlisea (Lentibulariaceae) Digestive
... the sessile hairs of Byblis and Pinguicula, and suggested that their function and mechanism were also similar. For a proper understanding of the functions of the trap, detailed knowledge of the ultrastructure of these hairs is required. On that basis, comparison of digestive hair ultrastructure in P ...
... the sessile hairs of Byblis and Pinguicula, and suggested that their function and mechanism were also similar. For a proper understanding of the functions of the trap, detailed knowledge of the ultrastructure of these hairs is required. On that basis, comparison of digestive hair ultrastructure in P ...
Co-ordination of signalling elements in guard cell ion
... under adverse environmental conditions. Thus, the size of the stomatal aperture optimizes gas exchange for overall plant performance. This balance of requirements is achieved by the precise tuning of guard cell turgor pressure and on the molecular level is accomplished by means of fine temporal and ...
... under adverse environmental conditions. Thus, the size of the stomatal aperture optimizes gas exchange for overall plant performance. This balance of requirements is achieved by the precise tuning of guard cell turgor pressure and on the molecular level is accomplished by means of fine temporal and ...
Herpes simplex virus type 1 alters transcript levels of tumor
... subsequent resolution of immune and/or inflammatory responses to a variety of pathogens. These multifunctional soluble mediators are produced locally and act either in an autocrine or a paracrine manner. The cytokine balance during a host immune response to an infectious agent influences whether the ...
... subsequent resolution of immune and/or inflammatory responses to a variety of pathogens. These multifunctional soluble mediators are produced locally and act either in an autocrine or a paracrine manner. The cytokine balance during a host immune response to an infectious agent influences whether the ...
The cell biology of bone metabolism
... well recognised mechanical functions: it provides rigidity and shape, protection and support for body structures, and aids locomotion. Contrary to popular belief, bone is in fact a highly dynamic structure undergoing constant remodelling. This bone turnover allows the bone to repair itself, for exam ...
... well recognised mechanical functions: it provides rigidity and shape, protection and support for body structures, and aids locomotion. Contrary to popular belief, bone is in fact a highly dynamic structure undergoing constant remodelling. This bone turnover allows the bone to repair itself, for exam ...
1. INTRODUCTION The skin is the largest organ in the human body
... have injured or crushed tissues lying below the tissue point. These wounds are commonly known as bruises and it will be visible due to discoloration resulting from the rupturing of blood capillaries in the injured area. Different types of open wounds are based on the manner in which the skin or tis ...
... have injured or crushed tissues lying below the tissue point. These wounds are commonly known as bruises and it will be visible due to discoloration resulting from the rupturing of blood capillaries in the injured area. Different types of open wounds are based on the manner in which the skin or tis ...
Biologically Induced Mineralization by Bacteria
... the inner face of the outer membrane. In gram-negative cells, it is the LPS that is the major factor in catalyzing mineral formation because of its high concentration of phosphate and carboxyl groups (Ferris and Beveridge 1984, 1986a). Members of the Archaea also show gram-positive and gram-negative ...
... the inner face of the outer membrane. In gram-negative cells, it is the LPS that is the major factor in catalyzing mineral formation because of its high concentration of phosphate and carboxyl groups (Ferris and Beveridge 1984, 1986a). Members of the Archaea also show gram-positive and gram-negative ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.