IMMUNOLOGY
... Not all of Ig have the functions of Ab, e.g. Patients with multiple myeloma have very high levels of Ig, but not Ab (to irrelevant things)) Secreted Ig (sIg)- mediated humoral immunity Membrane Ig (mIg): BCR B cell receptor ...
... Not all of Ig have the functions of Ab, e.g. Patients with multiple myeloma have very high levels of Ig, but not Ab (to irrelevant things)) Secreted Ig (sIg)- mediated humoral immunity Membrane Ig (mIg): BCR B cell receptor ...
Cell Alloimmunization Hemin Controls T Cell Polarization in Sickle
... Patients with sickle cell disease (SCD) often require transfusions to treat and prevent worsening anemia and other SCD complications. However, transfusions can trigger alloimmunization against transfused RBCs with serious clinical sequelae. Risk factors for alloimmunization in SCD remain poorly unde ...
... Patients with sickle cell disease (SCD) often require transfusions to treat and prevent worsening anemia and other SCD complications. However, transfusions can trigger alloimmunization against transfused RBCs with serious clinical sequelae. Risk factors for alloimmunization in SCD remain poorly unde ...
Study The Effects Of Methotrexate (MTX) On Some Parameters Of
... reproduction of the cancer cells. Methotrexate is used in much smaller doses for the treatment of rheumatoid arthritis, Crohn’s disease and psoriasis [1]. Methotrexate is known to be teratogenic in women, but few data are available on the effects of methotrexate on male reproductive capability. Stud ...
... reproduction of the cancer cells. Methotrexate is used in much smaller doses for the treatment of rheumatoid arthritis, Crohn’s disease and psoriasis [1]. Methotrexate is known to be teratogenic in women, but few data are available on the effects of methotrexate on male reproductive capability. Stud ...
Mona Sayed Ahmed Mohammed Ellithey S12000541
... with a selectivity index of SI 8.1 which was confirmed by real time cell electronic sensing (RT-CES). Compounds 2, 7 and 8 showed strong inhibitory activity against HIV-1 PR at IC50‘s of 7.2 ±0.7, 4.85±0.2 and 4.80 ±0.9 µM respectively. Docking studies gave comparable scores when comparing the bindi ...
... with a selectivity index of SI 8.1 which was confirmed by real time cell electronic sensing (RT-CES). Compounds 2, 7 and 8 showed strong inhibitory activity against HIV-1 PR at IC50‘s of 7.2 ±0.7, 4.85±0.2 and 4.80 ±0.9 µM respectively. Docking studies gave comparable scores when comparing the bindi ...
A Pd8 Tetrafacial Molecular Barrel as Carrier for Water Insoluble
... synthesis of the famous “molecular square” in 1990 via this approach, the next two decades have seen a tremendous growth in this field with the introduction of numerous fascinating twodimensional (2D) and three-dimensional (3D) architectures of diverse shapes, sizes and functionality.2 While, the “mo ...
... synthesis of the famous “molecular square” in 1990 via this approach, the next two decades have seen a tremendous growth in this field with the introduction of numerous fascinating twodimensional (2D) and three-dimensional (3D) architectures of diverse shapes, sizes and functionality.2 While, the “mo ...
The Assimilation of Amino-acids by Bacteria
... (Gale & Mitchell, 1947). The protein synthesis takes place only in growing cells and can be eliminated by working with well-washed suspensions of cells. The remaining metabolism (transfer of glutamic acid to the metabolic pool), which takes place in resting and growing cells, can be inhibited by sui ...
... (Gale & Mitchell, 1947). The protein synthesis takes place only in growing cells and can be eliminated by working with well-washed suspensions of cells. The remaining metabolism (transfer of glutamic acid to the metabolic pool), which takes place in resting and growing cells, can be inhibited by sui ...
Muscle Injury and the Role of Myosatellite Cells in Muscle Healing
... indentation or a bump may be felt underneath the skin at the site of greatest pain. In a second-degree tear, muscle fibers have been torn but the tear does not go all the way through the thickness of the muscle. A third-degree tear is the most painful and serious type of tear. In a third-degree musc ...
... indentation or a bump may be felt underneath the skin at the site of greatest pain. In a second-degree tear, muscle fibers have been torn but the tear does not go all the way through the thickness of the muscle. A third-degree tear is the most painful and serious type of tear. In a third-degree musc ...
Cytomechanical properties of papaver pollen tubes are altered after
... bending of a horizontal glass beam gauges the resistance to cellular deformation performed by a vertical glass stylus attached to one end of the beam. The other end of the beam is mounted on a linear piezoelectric motor which moves vertically according to a programmed waveform. Optical sensors monit ...
... bending of a horizontal glass beam gauges the resistance to cellular deformation performed by a vertical glass stylus attached to one end of the beam. The other end of the beam is mounted on a linear piezoelectric motor which moves vertically according to a programmed waveform. Optical sensors monit ...
midlife crisis encodes a conserved zinc
... A defining characteristic of stem cells is the ability to produce daughters that retain stem cell fate (self-renew) as well as daughters that begin the process of differentiation. The robust adoption of these distinct fates is crucial both for the maintenance of stem cell pool size and for the produ ...
... A defining characteristic of stem cells is the ability to produce daughters that retain stem cell fate (self-renew) as well as daughters that begin the process of differentiation. The robust adoption of these distinct fates is crucial both for the maintenance of stem cell pool size and for the produ ...
observations on luminescence in noctiluca
... The response is registered as a downward deflexion of the trace and is superposed on background noise. Time scale, 10 msec. Temp. 17° C. c, response of a Noctiluca cell to a single electrical shock, Time scale, 10 msec. Temp, IgO C. d-g, electrical stimulation of a Noctiluca cell at various frequenc ...
... The response is registered as a downward deflexion of the trace and is superposed on background noise. Time scale, 10 msec. Temp. 17° C. c, response of a Noctiluca cell to a single electrical shock, Time scale, 10 msec. Temp, IgO C. d-g, electrical stimulation of a Noctiluca cell at various frequenc ...
Developmental stage‐specific expression of Rbm suggests its
... were af®nity-puri®ed. Immunoblot analysis revealed a single band of 43 kDa in size that, among tissues tested, was speci®c to the testis (Figure 2A). The molecular weight of the Rbm-speci®c band concurred with the predicted size of the protein. Moreover, ectopic expression of Rbm in cultured cells a ...
... were af®nity-puri®ed. Immunoblot analysis revealed a single band of 43 kDa in size that, among tissues tested, was speci®c to the testis (Figure 2A). The molecular weight of the Rbm-speci®c band concurred with the predicted size of the protein. Moreover, ectopic expression of Rbm in cultured cells a ...
1 An amoeba phagocytosis model reveals a novel developmental
... At high amoeba densities, the bacteria change morphology into long filaments ...
... At high amoeba densities, the bacteria change morphology into long filaments ...
Loss of PTEN Promotes Tumor Development in
... Inc. and electrophoresed according to the manufacturer’s instructions, followed by transfer of the proteins to polyvinylidene difluoride membrane from Pall Corporation (Ann Arbor, MI). The blots were probed with the appropriate primary antibody according to each supplier’s recommendations. Antibodie ...
... Inc. and electrophoresed according to the manufacturer’s instructions, followed by transfer of the proteins to polyvinylidene difluoride membrane from Pall Corporation (Ann Arbor, MI). The blots were probed with the appropriate primary antibody according to each supplier’s recommendations. Antibodie ...
B as a Synthetic Lethal Screen Identifies NF- for patients with Neuroblastoma
... also administered during the maintenance period post chemotherapy. Recent clinical trials have shown that the combination of anti-GD2 antibodies and immunocytokines significantly increase the survival of patients with high risk neuroblastoma [6,7]. Despite these aggressive combined multimodal treatm ...
... also administered during the maintenance period post chemotherapy. Recent clinical trials have shown that the combination of anti-GD2 antibodies and immunocytokines significantly increase the survival of patients with high risk neuroblastoma [6,7]. Despite these aggressive combined multimodal treatm ...
Topological schemas of cognitive maps and spatial learning in the
... A key property of our approach, crucial for modeling spatial learning, is that schemas are dynamic objects. As an animal explores a novel environment, new regions become represented by the activity of place cells and new relationships are inferred from the spike trains’ temporal patterns [9, 10]. Ac ...
... A key property of our approach, crucial for modeling spatial learning, is that schemas are dynamic objects. As an animal explores a novel environment, new regions become represented by the activity of place cells and new relationships are inferred from the spike trains’ temporal patterns [9, 10]. Ac ...
Nanoscale Research Letters
... However, these polymers are characterized by a high hydrophobicity and slow degradation rate that can represent in some cases a disadvantage for their use as drug carriers [7]. In the family of polyesters, polycaprolactone (PCL) shows an excellent biocompatibility and rapid degradability, good misc ...
... However, these polymers are characterized by a high hydrophobicity and slow degradation rate that can represent in some cases a disadvantage for their use as drug carriers [7]. In the family of polyesters, polycaprolactone (PCL) shows an excellent biocompatibility and rapid degradability, good misc ...
Molecular - College of Biological Sciences
... in mouse (Fisk and Winey, 2001) and human (Fisk et al., 2003) cells, and its overexpression in mouse cells causes centrosome reduplication (Fisk and Winey, 2001). Furthermore, overexpression of a catalytically inactive version of Mps1 (Mps1KD) prevents centrosome duplication in mouse (Fisk and Winey ...
... in mouse (Fisk and Winey, 2001) and human (Fisk et al., 2003) cells, and its overexpression in mouse cells causes centrosome reduplication (Fisk and Winey, 2001). Furthermore, overexpression of a catalytically inactive version of Mps1 (Mps1KD) prevents centrosome duplication in mouse (Fisk and Winey ...
14-3-3 associates with cell surface aminopeptidase N in the
... direct tissue development and repair. Increasing evidence suggests that bidirectional signaling between stromal and epithelial cells plays a crucial role in maintaining the integrity of the extracellular matrix (ECM) and that a disruption in this communication can lead to fibrogenesis (Deitch et al. ...
... direct tissue development and repair. Increasing evidence suggests that bidirectional signaling between stromal and epithelial cells plays a crucial role in maintaining the integrity of the extracellular matrix (ECM) and that a disruption in this communication can lead to fibrogenesis (Deitch et al. ...
1 METT-10, A Putative Methyltransferase, Inhibits Germ
... From early development to later life, tissues are formed from and maintained by stem cell populations. Stem cells have the unique ability to give rise to both differentiated cell types and self-renewing daughters, and must regulate the choice between the two. A balance between proliferation and diff ...
... From early development to later life, tissues are formed from and maintained by stem cell populations. Stem cells have the unique ability to give rise to both differentiated cell types and self-renewing daughters, and must regulate the choice between the two. A balance between proliferation and diff ...
In-Cell Solid-State NMR - Institut de Biologie Physico
... (1), and 15 years later the focus shifted from looking at water molecules to examining lipids (2) and small metabolites (3). In the 2000s, larger soluble proteins within bacterial cells were studied by NMR (4), and in-cell NMR became a field in and of itself, with investigators identifying common ob ...
... (1), and 15 years later the focus shifted from looking at water molecules to examining lipids (2) and small metabolites (3). In the 2000s, larger soluble proteins within bacterial cells were studied by NMR (4), and in-cell NMR became a field in and of itself, with investigators identifying common ob ...
CLL Information for Patients and Caregivers Chronic Lymphocytic Leukemia 2012
... your questions, give support and provide any needed referrals. Let your doctor know if you want a professional healthcare interpreter who speaks your native language or uses sign language. Many times, this is a free service. The news that you have CLL may be a shock to you and your loved ones. You m ...
... your questions, give support and provide any needed referrals. Let your doctor know if you want a professional healthcare interpreter who speaks your native language or uses sign language. Many times, this is a free service. The news that you have CLL may be a shock to you and your loved ones. You m ...
Target or barrier? The cell wall of early- and later
... plant cell wall. The cell wall is the outermost structure of plant ...
... plant cell wall. The cell wall is the outermost structure of plant ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.