BCL-6 Negatively Regulates Expression of the NF- p50 Subunit B1 p105/
... IKK-dependent and IKK-independent mechanisms (27–29). It is therefore conceivable that NF-B not only can be activated in response to CSF-1 signaling in macrophages (30, 31), but also plays an important role in regulating CSF-1-mediated cell proliferation. At the onset of this work, we were intrigue ...
... IKK-dependent and IKK-independent mechanisms (27–29). It is therefore conceivable that NF-B not only can be activated in response to CSF-1 signaling in macrophages (30, 31), but also plays an important role in regulating CSF-1-mediated cell proliferation. At the onset of this work, we were intrigue ...
Mechanisms Shaping the Membranes of Cellular Organelles
... mid surface [bilayer-coupling mechanism (Sheetz & Singer 1974)]. In agreement with these predictions, it has been found experimentally that high mole fractions of some lipids can ...
... mid surface [bilayer-coupling mechanism (Sheetz & Singer 1974)]. In agreement with these predictions, it has been found experimentally that high mole fractions of some lipids can ...
Role of glutamate on T-cell mediated immunity
... Service of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain Received 21 November 2006; received in revised form 9 January 2007; accepted 10 January 2007 ...
... Service of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain Received 21 November 2006; received in revised form 9 January 2007; accepted 10 January 2007 ...
Linköping University Post Print
... lysosomes are filled with more than 50 acid hydrolases, including phosphatases, nucleases, glycosidases, proteases, peptidases, sulphatases, and lipases [2]. Of the lysosomal hydrolases, the cathepsin family of proteases is the best characterized. The cathepsins are subdivided, according to their ac ...
... lysosomes are filled with more than 50 acid hydrolases, including phosphatases, nucleases, glycosidases, proteases, peptidases, sulphatases, and lipases [2]. Of the lysosomal hydrolases, the cathepsin family of proteases is the best characterized. The cathepsins are subdivided, according to their ac ...
MAPK Phosphatase AP2C3 Induces Ectopic Proliferation of
... transcription factors that are successively ushering cells though the steps of stomata lineage: SPEECHLESS (SPCH) - initiation;, MUTE - proliferation; and FAMA - stomata differentiation [13,14,15,16]. Phosphorylation of SPCH by MPK6 was shown to control the entry into stomata lineage and to connect ...
... transcription factors that are successively ushering cells though the steps of stomata lineage: SPEECHLESS (SPCH) - initiation;, MUTE - proliferation; and FAMA - stomata differentiation [13,14,15,16]. Phosphorylation of SPCH by MPK6 was shown to control the entry into stomata lineage and to connect ...
Comparison of Methods for Estimating Unbound Intracellular
... Determination of the Intracellular Volume of Hepatocytes. The intracellular volume of rat hepatocytes (3.68 6 1.37 mL/106 cells) was estimated using published methods (Supplemental Table 1A) (Baur et al., 1975; Kletzien et al., 1975; Eaton and Klaassen, 1978; Kristensen and Folke, 1984; Yamazaki et ...
... Determination of the Intracellular Volume of Hepatocytes. The intracellular volume of rat hepatocytes (3.68 6 1.37 mL/106 cells) was estimated using published methods (Supplemental Table 1A) (Baur et al., 1975; Kletzien et al., 1975; Eaton and Klaassen, 1978; Kristensen and Folke, 1984; Yamazaki et ...
Pattern recognition receptors and control of adaptive immunity
... Two related checkpoints in the adaptive immune response control the magnitude and duration of the response, which should correlate with the extent and persistence of infection, respectively. Unlike the origin of the antigen or the class of pathogen, the magnitude and duration of a response are grade ...
... Two related checkpoints in the adaptive immune response control the magnitude and duration of the response, which should correlate with the extent and persistence of infection, respectively. Unlike the origin of the antigen or the class of pathogen, the magnitude and duration of a response are grade ...
Respiratory Elicitors from Rhizobium meliloti Affect Intact Alfalfa Roots
... difficult to determine when both roots and microbes are respiring (Cheng et al., 1993; Swinnen, 1994). It is possible that increases in root-plus-bacterial respiration result when soil microorganisms first enhance root exudation and then respire C compounds in the exudate (Meharg and Killham, 1991). ...
... difficult to determine when both roots and microbes are respiring (Cheng et al., 1993; Swinnen, 1994). It is possible that increases in root-plus-bacterial respiration result when soil microorganisms first enhance root exudation and then respire C compounds in the exudate (Meharg and Killham, 1991). ...
Design and physicochemical characterisation of novel
... Diffusion of ibuprofen sodium released from dissolving PMVE/MA MN arrays across dermatomed (350 μm) neonatal porcine skin was investigated in vitro using the modified Franz diffusion cells, as described previously [11] (Fig. 1D). The MN array was placed on top of the skin and again inserted using the ...
... Diffusion of ibuprofen sodium released from dissolving PMVE/MA MN arrays across dermatomed (350 μm) neonatal porcine skin was investigated in vitro using the modified Franz diffusion cells, as described previously [11] (Fig. 1D). The MN array was placed on top of the skin and again inserted using the ...
P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct
... computer program COMPARE determines the correlation between a compound of interest and each compound in the database, ranking them by correlation coefficient. High correlation coefficients are obtained between compounds with similar cytotoxicity profiles, even if they are not structurally similar (2 ...
... computer program COMPARE determines the correlation between a compound of interest and each compound in the database, ranking them by correlation coefficient. High correlation coefficients are obtained between compounds with similar cytotoxicity profiles, even if they are not structurally similar (2 ...
Multiple mechanisms determine the order of APC/C substrate
... inhibits Clb5 degradation, and that the timing of Clb5 degradation onset in the absence of the SAC likely indicates the time when APC/CCdc20 becomes active, possibly as a result of APC/C phosphorylation by Cdk1 (Rudner and Murray, 2000; Kraft et al., 2003). In addition, the rate of Clb5 degradation ...
... inhibits Clb5 degradation, and that the timing of Clb5 degradation onset in the absence of the SAC likely indicates the time when APC/CCdc20 becomes active, possibly as a result of APC/C phosphorylation by Cdk1 (Rudner and Murray, 2000; Kraft et al., 2003). In addition, the rate of Clb5 degradation ...
Involvement of Calcium Ion in the Stimulated Shoot Elongation of
... MES buffer, pH 6.5, containing various chemicals). The upper half of each shoot was keep emergent from the buffer in the vial. The vial was covered with parafilm and incubated at 25°C in the dark. For anaerobic treatment, on the other hand, three tubers were put together in a small glass vessel (2.5 ...
... MES buffer, pH 6.5, containing various chemicals). The upper half of each shoot was keep emergent from the buffer in the vial. The vial was covered with parafilm and incubated at 25°C in the dark. For anaerobic treatment, on the other hand, three tubers were put together in a small glass vessel (2.5 ...
Mesoderm commitment to hematopoiesis - Development
... lineages in immediate proximity to each other (Haar and Ackerman, 1971). This observation provided the basis for the hypothesis, first put forward in the early 1900s, that these lineages derive from a common bi-potential precursor, a cell termed the hemangioblast (Sabin, 1920; Murray, 1932; and revi ...
... lineages in immediate proximity to each other (Haar and Ackerman, 1971). This observation provided the basis for the hypothesis, first put forward in the early 1900s, that these lineages derive from a common bi-potential precursor, a cell termed the hemangioblast (Sabin, 1920; Murray, 1932; and revi ...
Patent ductus arteriosus in mice with smooth muscle
... additional contractile smooth muscle cell markers, such as smooth muscle a-actin (SMA; also known as ACTA2) and smooth muscle myosin heavy chain (SMMHC; also known as MYH11), defects in vascular smooth muscle cell differentiation in the ductus arteriosus and descending aorta of Jag1-SMcko embryos co ...
... additional contractile smooth muscle cell markers, such as smooth muscle a-actin (SMA; also known as ACTA2) and smooth muscle myosin heavy chain (SMMHC; also known as MYH11), defects in vascular smooth muscle cell differentiation in the ductus arteriosus and descending aorta of Jag1-SMcko embryos co ...
PDF - Bezanilla Lab
... (d ) Seven-day-old sporeling. The first rapidly growing caulonemal filaments can be seen emerging from the central chloronemal tissue. Scale bar: 500 μm. (e) Twenty-two-day-old culture. Scale bar: 10 mm. ( f ) Detail of 22-day-old culture. The main axes are caulonemal filaments, extending by the divisi ...
... (d ) Seven-day-old sporeling. The first rapidly growing caulonemal filaments can be seen emerging from the central chloronemal tissue. Scale bar: 500 μm. (e) Twenty-two-day-old culture. Scale bar: 10 mm. ( f ) Detail of 22-day-old culture. The main axes are caulonemal filaments, extending by the divisi ...
Full Text - Global Science Books
... REFERENCES........................................................................................................................................................................................... 223 ...
... REFERENCES........................................................................................................................................................................................... 223 ...
Gene Deletion Screen for Cardiomyopathy in Adult Drosophila
... allowed us to narrow the candidate interval to 16 genes (Figure 1C through 1E). Because the majority of homozygous deletions are lethal, deficiency stocks are maintained as heterozygotes in the presence of a balancer chromosome. Because the cardiomyopathic phenotype in Df(2L)Exel7007 and Df(2L)Exel8 ...
... allowed us to narrow the candidate interval to 16 genes (Figure 1C through 1E). Because the majority of homozygous deletions are lethal, deficiency stocks are maintained as heterozygotes in the presence of a balancer chromosome. Because the cardiomyopathic phenotype in Df(2L)Exel7007 and Df(2L)Exel8 ...
antoniadi_et_al._2015.
... After optimizing the microSPE protocol and validation of protoplast isolation and sorting steps, we were able to quantify CK metabolites in the apical root cell types under study. These included the tissues of epidermis and cortex (J2812:GFP expression), stele (pWOODEN LEG:GFP [pWOL:GFP] expression) ...
... After optimizing the microSPE protocol and validation of protoplast isolation and sorting steps, we were able to quantify CK metabolites in the apical root cell types under study. These included the tissues of epidermis and cortex (J2812:GFP expression), stele (pWOODEN LEG:GFP [pWOL:GFP] expression) ...
Intracellular trafficking of GO
... Despite aggressive therapies, AML remains difficult to treat, and many patients will die as a consequence of treatment failure or complications from either treatment-related toxicities or impaired normal hematopoiesis. With contemporary 5-year relative survival rates of ~55% for patients <45 years o ...
... Despite aggressive therapies, AML remains difficult to treat, and many patients will die as a consequence of treatment failure or complications from either treatment-related toxicities or impaired normal hematopoiesis. With contemporary 5-year relative survival rates of ~55% for patients <45 years o ...
ExamplePoster3 - Bridgewater College
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
Microbial Cell Factories
... due to their implications not only in bacterial colonization of abiotic surfaces with an economic value, but also in almost all pathogenic infections, making them recalcitrant due to their multidrug resistance. Initially, the proposed function for cellulose in bacteria was not linked to biofilm form ...
... due to their implications not only in bacterial colonization of abiotic surfaces with an economic value, but also in almost all pathogenic infections, making them recalcitrant due to their multidrug resistance. Initially, the proposed function for cellulose in bacteria was not linked to biofilm form ...
Lineage-specific stem cells, signals and asymmetries
... photosynthetic tissues, an undifferentiated protodermal cell adopts a meristemoid mother cell (MMC, purple) identity and undergoes an asymmetric cell division (ACD), giving rise to a meristemoid (cyan). This initial step is directed by SPCH-SCRM protein heterodimers, which amplify their own expressi ...
... photosynthetic tissues, an undifferentiated protodermal cell adopts a meristemoid mother cell (MMC, purple) identity and undergoes an asymmetric cell division (ACD), giving rise to a meristemoid (cyan). This initial step is directed by SPCH-SCRM protein heterodimers, which amplify their own expressi ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.