Fighting Viral Infections and Virus
... functionally distinct subsets of helper CD4+ T cells have been identified and characterized. Th17 cells control fungi and extracellular bacteria through the release of IL-17 and IL-22 (16, 17). Follicular helper T cells reside in B cell follicles and are essential for the generation of B cell memory ...
... functionally distinct subsets of helper CD4+ T cells have been identified and characterized. Th17 cells control fungi and extracellular bacteria through the release of IL-17 and IL-22 (16, 17). Follicular helper T cells reside in B cell follicles and are essential for the generation of B cell memory ...
pdf, 1.1 MB - The Nebenführ Lab
... persists until completion of cytokinesis. Maintenance of the distinct localizations does not depend on intact actin filaments or microtubules, although the mitotic spindle appears to play a major role in organizing the organelle distribution patterns. The redistribution of Golgi stacks during mitosi ...
... persists until completion of cytokinesis. Maintenance of the distinct localizations does not depend on intact actin filaments or microtubules, although the mitotic spindle appears to play a major role in organizing the organelle distribution patterns. The redistribution of Golgi stacks during mitosi ...
CDK5 is a major regulator of the tumor suppressor DLC1
... To establish whether an endogenous protein complex containing DLC1 and CDK5 exists in vivo, we performed coimmunoprecipitation (co-IP) experiments from two non-small cell lung cancer (NSCLC) lines, H1703 and H157, which expressed both proteins. DLC1 and CDK5 formed a protein complex in both lines (F ...
... To establish whether an endogenous protein complex containing DLC1 and CDK5 exists in vivo, we performed coimmunoprecipitation (co-IP) experiments from two non-small cell lung cancer (NSCLC) lines, H1703 and H157, which expressed both proteins. DLC1 and CDK5 formed a protein complex in both lines (F ...
Molecular mechanism of protrusion formation during Listeria Keith Ireton Luciano A. Rigano
... (Rajabian et al., 2009). Specifically, the defect in protrusions normally observed with this mutant is suppressed when Tuba is depleted through RNA interference (RNAi). Importantly, Tuba depletion has no effect on protrusion formation by wild-type Listeria expressing InlC. These genetic data indicat ...
... (Rajabian et al., 2009). Specifically, the defect in protrusions normally observed with this mutant is suppressed when Tuba is depleted through RNA interference (RNAi). Importantly, Tuba depletion has no effect on protrusion formation by wild-type Listeria expressing InlC. These genetic data indicat ...
From the regulation of peptidoglycan synthesis to bacterial growth
... in the sacculus to allow the newly attached material to insert into the layer without increasing its thickness. Peptidoglycan cleavage is also required for reductive cell division and cell separation. E. coli has at least 13 periplasmic peptidoglycan hydrolases (autolysins), which can collectively c ...
... in the sacculus to allow the newly attached material to insert into the layer without increasing its thickness. Peptidoglycan cleavage is also required for reductive cell division and cell separation. E. coli has at least 13 periplasmic peptidoglycan hydrolases (autolysins), which can collectively c ...
Granulocyte-Colony Stimulating Factor Therapy to Induce
... Formand for bedømmelsesudvalget: Professor, overlæge, dr.med. Niels Borregaard ...
... Formand for bedømmelsesudvalget: Professor, overlæge, dr.med. Niels Borregaard ...
- Journal of Clinical Investigation
... cytosol defect was even more striking [0.3 and 0.6% of control] when each patient's cytosol was tested against his own membranes appears to be due to small amounts of cytosol factor which remain associated with some preparations of control membranes.) The defect in the CGD cytosol did not appear to ...
... cytosol defect was even more striking [0.3 and 0.6% of control] when each patient's cytosol was tested against his own membranes appears to be due to small amounts of cytosol factor which remain associated with some preparations of control membranes.) The defect in the CGD cytosol did not appear to ...
Separate Functions of Gelsolin Mediate Sequential Steps of
... When creating actin filament severing mutants of gelsolin, the choice of altered residues was directed by the following considerations: the aminoterminal half of gelsolin is largely responsible for severing and capping activities and is regulated by phosphoinositides (Janmey and Stossel, 1987; Yin, ...
... When creating actin filament severing mutants of gelsolin, the choice of altered residues was directed by the following considerations: the aminoterminal half of gelsolin is largely responsible for severing and capping activities and is regulated by phosphoinositides (Janmey and Stossel, 1987; Yin, ...
copyrighted material - Edinburgh Cell Wall Group
... D- and L-), distinguished by the orientation of the C–O bond of the penultimate C atom. Galactose is the only wall residue known to occur as both D- and L-enantiomer. Note that D- and L-Gal differ in orientation of the C–O bond at all four non-anomeric, chiral centres (= carbons 2, 3, 4 and 5; the d ...
... D- and L-), distinguished by the orientation of the C–O bond of the penultimate C atom. Galactose is the only wall residue known to occur as both D- and L-enantiomer. Note that D- and L-Gal differ in orientation of the C–O bond at all four non-anomeric, chiral centres (= carbons 2, 3, 4 and 5; the d ...
Molecular Plant-Microbe Interaction
... zones (Fig. 3C), indicating the presence of β-1,4 polysaccharides, and nonreactive, electron-translucent zones suggesting the possible presence of callose. Non-esterified pectin accumulated in the interface around intracellular arbuscule trunks in cortical host cells (Fig. 4A) but these molecules co ...
... zones (Fig. 3C), indicating the presence of β-1,4 polysaccharides, and nonreactive, electron-translucent zones suggesting the possible presence of callose. Non-esterified pectin accumulated in the interface around intracellular arbuscule trunks in cortical host cells (Fig. 4A) but these molecules co ...
Active gel physics
... The continuity equation describing the balance of polymerized actin mass has both source and sink terms, whereas the total actin mass is conserved (Box 1, equation (4)). All conservation equations for scalar densities have not only convection and diffusion fluxes, but they have additional terms chara ...
... The continuity equation describing the balance of polymerized actin mass has both source and sink terms, whereas the total actin mass is conserved (Box 1, equation (4)). All conservation equations for scalar densities have not only convection and diffusion fluxes, but they have additional terms chara ...
Cell-cycle-regulated expression of STIL controls centriole number in
... To study the association of STIL with centrioles throughout the cell cycle, we stained asynchronously growing U2OS cells with antibodies against STIL, CP110 and Cep135. Cep135 served as a marker for centrioles and CP110 was used to time the emergence of newly forming centrioles during S phase (Chen ...
... To study the association of STIL with centrioles throughout the cell cycle, we stained asynchronously growing U2OS cells with antibodies against STIL, CP110 and Cep135. Cep135 served as a marker for centrioles and CP110 was used to time the emergence of newly forming centrioles during S phase (Chen ...
Tissue Engineered Human Skin Equivalents
... and mechanical signals and regulate tissue development [14]. Bioreactors have three major components: metabolically active cells that express their differentiated phenotype and produce ECM; polymeric scaffolds providing three dimensional structural supports for cell attachment and tissue growth, bei ...
... and mechanical signals and regulate tissue development [14]. Bioreactors have three major components: metabolically active cells that express their differentiated phenotype and produce ECM; polymeric scaffolds providing three dimensional structural supports for cell attachment and tissue growth, bei ...
Immunohistochemical sweat gland profiles
... binds to a-fucose moiety with a high specificity through complementary sugar-binding sites. Lectins were used to demonstrate the presence of complex carbohydrate moieties at the cell surface or in cytoplasmic organelles in skin appendages. However, little is known about the precise composition and d ...
... binds to a-fucose moiety with a high specificity through complementary sugar-binding sites. Lectins were used to demonstrate the presence of complex carbohydrate moieties at the cell surface or in cytoplasmic organelles in skin appendages. However, little is known about the precise composition and d ...
plantcell.org
... QC (Feldman, 1976). To begin to understand how radial patterning occurs during regeneration of the maize root tip, we made two types of excisions and used ZmSCR expression as a marker for radial patterning. The first excision involved removal of the entire root tip, including the root cap and QC, an ...
... QC (Feldman, 1976). To begin to understand how radial patterning occurs during regeneration of the maize root tip, we made two types of excisions and used ZmSCR expression as a marker for radial patterning. The first excision involved removal of the entire root tip, including the root cap and QC, an ...
Maintenance of ZPA signaling in cultured mouse limb bud cells
... In the limb bud, ZPA signaling is controlled both spatially and temporally. Using chick tissue, maps of ZPA signaling have been established for different developmental stages of the chick wing bud (MacCabe et al., 1973; Honig and Summerbell, 1985); ZPA signaling is localized to the posterior region ...
... In the limb bud, ZPA signaling is controlled both spatially and temporally. Using chick tissue, maps of ZPA signaling have been established for different developmental stages of the chick wing bud (MacCabe et al., 1973; Honig and Summerbell, 1985); ZPA signaling is localized to the posterior region ...
Hard Shell Capsules
... Among solid dosage forms, the capsule is second only to the compressed tablet in frequency of utilization for drug delivery. Given the unique advantages of this dosage form, the popularity of the capsule should not be surprising. For instance, because the medication is contained within the capsule s ...
... Among solid dosage forms, the capsule is second only to the compressed tablet in frequency of utilization for drug delivery. Given the unique advantages of this dosage form, the popularity of the capsule should not be surprising. For instance, because the medication is contained within the capsule s ...
Lysosomal Function and Dysfunction
... ribosomes, peroxisomes, and endoplasmic reticulum. Alteration on some of these pathways may have important implication in diseases such as cancer and neurodegeneration. ...
... ribosomes, peroxisomes, and endoplasmic reticulum. Alteration on some of these pathways may have important implication in diseases such as cancer and neurodegeneration. ...
Ultrastructural immunocytochemical localization of
... and the subsequent wash was performed as in the PAP method. Embryos were then incubated in biotinylated antirabbit IgG (Vector Laboratories Inc.), diluted 1:5 with PBS + g.s., for 1 h. After washing with PBS + g.s. for 1 h with two changes, the specimens were immersed in ferritin-congugated avidin D ...
... and the subsequent wash was performed as in the PAP method. Embryos were then incubated in biotinylated antirabbit IgG (Vector Laboratories Inc.), diluted 1:5 with PBS + g.s., for 1 h. After washing with PBS + g.s. for 1 h with two changes, the specimens were immersed in ferritin-congugated avidin D ...
Physiological implications of the regulation of vacuolar
... Intracellular V-ATPases are important for receptor-mediated endocytosis and intracellular trafficking, protein processing and degradation, coupled transport of small molecules and ions, and the entry of various pathogens into cells (4). An important model for the study of intracellular organelle H-A ...
... Intracellular V-ATPases are important for receptor-mediated endocytosis and intracellular trafficking, protein processing and degradation, coupled transport of small molecules and ions, and the entry of various pathogens into cells (4). An important model for the study of intracellular organelle H-A ...
as a PDF
... Higher plants cannot escape from the place where they germinate and settle, even if the environmental conditions drastically change. Plants have developed many mechanisms during the course of evolution to survive in such circumstances by changing growth direction or architecture of their body shape. ...
... Higher plants cannot escape from the place where they germinate and settle, even if the environmental conditions drastically change. Plants have developed many mechanisms during the course of evolution to survive in such circumstances by changing growth direction or architecture of their body shape. ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.