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... Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to t ...
... Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to t ...
Dazl regulates mouse embryonic germ cell development
... differentially from the very beginning of the specification process. Germ cells were thought to retain expression of genes associated with pluripotency such as Oct4, Nanog and Sox2 for much longer in embryogenesis than somatic cells (Scholer et al., 1989; Western et al., 2005; Yamaguchi et al., 200 ...
... differentially from the very beginning of the specification process. Germ cells were thought to retain expression of genes associated with pluripotency such as Oct4, Nanog and Sox2 for much longer in embryogenesis than somatic cells (Scholer et al., 1989; Western et al., 2005; Yamaguchi et al., 200 ...
Author`s personal copy
... is transported out of the nucleus to the cytoplasm, where it is cleaved by RNase III endonuclease DICER to generate a mature miRNA. The double-stranded miRNA, which is 21–25 nt long with 5′-phosphorylated ends and 2-nt 3′ overhangs, incorporates into a ribonucleoprotein complex, the RNA-induced sile ...
... is transported out of the nucleus to the cytoplasm, where it is cleaved by RNase III endonuclease DICER to generate a mature miRNA. The double-stranded miRNA, which is 21–25 nt long with 5′-phosphorylated ends and 2-nt 3′ overhangs, incorporates into a ribonucleoprotein complex, the RNA-induced sile ...
In tobacco leaf epidermal cells, the integrity of protein export from
... apparatus in living plant cells has yet to emerge. It has been shown that Arf1 localizes at the Golgi apparatus (Takeuchi et al., 2002) with the coatomer (Movafeghi et al., 1999; Pimpl et al., 2000; Ritzenthaler et al., 2002). However, a distribution of Arf1 on non-Golgi structures has also been ver ...
... apparatus in living plant cells has yet to emerge. It has been shown that Arf1 localizes at the Golgi apparatus (Takeuchi et al., 2002) with the coatomer (Movafeghi et al., 1999; Pimpl et al., 2000; Ritzenthaler et al., 2002). However, a distribution of Arf1 on non-Golgi structures has also been ver ...
In tobacco leaf epidermal cells, the integrity of protein export from
... apparatus in living plant cells has yet to emerge. It has been shown that Arf1 localizes at the Golgi apparatus (Takeuchi et al., 2002) with the coatomer (Movafeghi et al., 1999; Pimpl et al., 2000; Ritzenthaler et al., 2002). However, a distribution of Arf1 on non-Golgi structures has also been ver ...
... apparatus in living plant cells has yet to emerge. It has been shown that Arf1 localizes at the Golgi apparatus (Takeuchi et al., 2002) with the coatomer (Movafeghi et al., 1999; Pimpl et al., 2000; Ritzenthaler et al., 2002). However, a distribution of Arf1 on non-Golgi structures has also been ver ...
Unleashing the potential of the root hair cell as a
... Plant root is an organ composed of multiple cell types with different functions. This multicellular complexity limits our understanding of root biology because -omics studies performed at the level of the entire root reflect the average responses of all cells composing the organ. To overcome this dif ...
... Plant root is an organ composed of multiple cell types with different functions. This multicellular complexity limits our understanding of root biology because -omics studies performed at the level of the entire root reflect the average responses of all cells composing the organ. To overcome this dif ...
SirA enforces diploidy by inhibiting the replication
... rounds of replication by targeting the highly conserved replication initiation factor DnaA. We show that SirA interacts with DnaA and displaces it from the replication origin. As a result, expression of SirA during growth rapidly blocks replication and causes cell death in a DnaA-dependent manner. F ...
... rounds of replication by targeting the highly conserved replication initiation factor DnaA. We show that SirA interacts with DnaA and displaces it from the replication origin. As a result, expression of SirA during growth rapidly blocks replication and causes cell death in a DnaA-dependent manner. F ...
Eph/ephrin signaling maintains the boundary of
... for GFP, we found that GFP-positive DFCs in control embryos were all positioned less than 60 µm away from the intersection of the midline and the marginal line (Fig. 3H), whereas GFP-positive cells in ephb4b morphants showed a wider dispersal pattern with some cells locating 120 µm away from the int ...
... for GFP, we found that GFP-positive DFCs in control embryos were all positioned less than 60 µm away from the intersection of the midline and the marginal line (Fig. 3H), whereas GFP-positive cells in ephb4b morphants showed a wider dispersal pattern with some cells locating 120 µm away from the int ...
Promoting central nervous system regeneration: Lessons from
... sustentacular and microvillar cells. The intermediate or middle compartment of the epithelium contains the OSNs, which are typical bipolar nerve cells. In addition to the apical dendrite that projects to the luminal surface of the OE, each OSN also gives rise to a single axon that leaves the epithel ...
... sustentacular and microvillar cells. The intermediate or middle compartment of the epithelium contains the OSNs, which are typical bipolar nerve cells. In addition to the apical dendrite that projects to the luminal surface of the OE, each OSN also gives rise to a single axon that leaves the epithel ...
Solid-Phase Synthesis, Characterization, and Cellular Activities of
... attachment methods are either not discriminatory in terms of where the ND binds the peptide or protein or are limited in the length and complexity of peptide that can be bound.24–27 Furthermore, characterization of the ND surface after biological molecule attachment is very challenging due to the in ...
... attachment methods are either not discriminatory in terms of where the ND binds the peptide or protein or are limited in the length and complexity of peptide that can be bound.24–27 Furthermore, characterization of the ND surface after biological molecule attachment is very challenging due to the in ...
The Plasma Membrane of the Cyanobacterium
... development of the thylakoid membrane as an intracellular membrane compartment. Therefore, analyzing the cellular structure of G. violaceus may be valuable to define new concepts for the emergence of specialized membrane compartments and provide insights into structural and functional aspects of thy ...
... development of the thylakoid membrane as an intracellular membrane compartment. Therefore, analyzing the cellular structure of G. violaceus may be valuable to define new concepts for the emergence of specialized membrane compartments and provide insights into structural and functional aspects of thy ...
The Plasma Membrane of the Cyanobacterium
... development of the thylakoid membrane as an intracellular membrane compartment. Therefore, analyzing the cellular structure of G. violaceus may be valuable to define new concepts for the emergence of specialized membrane compartments and provide insights into structural and functional aspects of thy ...
... development of the thylakoid membrane as an intracellular membrane compartment. Therefore, analyzing the cellular structure of G. violaceus may be valuable to define new concepts for the emergence of specialized membrane compartments and provide insights into structural and functional aspects of thy ...
Vesicular transport of newly synthesized opsin from the Golgi
... min after light onset. Eye cups prepared by surgical removal of cornea, iris, and lens were fixed either in 2% paraformaldehyde and 2.5% glutaraldehyde in 0.1 M cacodylate buffer at pH 7.4 (tadpoles), the same aldehydes in 0.067 M cacodylate buffer (postmetamorphic juveniles), or 4% paraformaldehyde ...
... min after light onset. Eye cups prepared by surgical removal of cornea, iris, and lens were fixed either in 2% paraformaldehyde and 2.5% glutaraldehyde in 0.1 M cacodylate buffer at pH 7.4 (tadpoles), the same aldehydes in 0.067 M cacodylate buffer (postmetamorphic juveniles), or 4% paraformaldehyde ...
CFTR modulates lung secretory cell proliferation and - AJP-Lung
... technique for in utero transfer of genes via the amniotic fluid. This method results in sustained expression and high-efficiency adenovirus-mediated transfer to the fetus. Transfer to the developing epithelium is accomplished by direct injection of a replication-defective adenovirus into individual ...
... technique for in utero transfer of genes via the amniotic fluid. This method results in sustained expression and high-efficiency adenovirus-mediated transfer to the fetus. Transfer to the developing epithelium is accomplished by direct injection of a replication-defective adenovirus into individual ...
Morphine: CYP2D6 Modulation Human White Blood Cells Synthesize
... he immune-regulatory effects of opioid chemical messengers are well established (1, 2). Exogenously administered opiates are immunosuppressive, inhibiting both cellular and humoral responses via their cytokine-like effects in both the CNS and the periphery (2). In vitro exposure of human monocytes a ...
... he immune-regulatory effects of opioid chemical messengers are well established (1, 2). Exogenously administered opiates are immunosuppressive, inhibiting both cellular and humoral responses via their cytokine-like effects in both the CNS and the periphery (2). In vitro exposure of human monocytes a ...
Western et al., 2001 - UBC Blogs
... glutaraldehyde (unless otherwise stated) and stained with Toluidine blue. A, Mature wild-type ovule (0 d after pollination [DAP]). B, Wild-type seed coat at 4 DAP. Amyloplasts are visible (arrow) in the outermost two cell layers. C, Wild-type seed coat at 7 DAP. The amyloplasts are larger (arrow) an ...
... glutaraldehyde (unless otherwise stated) and stained with Toluidine blue. A, Mature wild-type ovule (0 d after pollination [DAP]). B, Wild-type seed coat at 4 DAP. Amyloplasts are visible (arrow) in the outermost two cell layers. C, Wild-type seed coat at 7 DAP. The amyloplasts are larger (arrow) an ...
Erythropoietin as an antiapoptotic, tissue
... EPO (EPOR) during specific phases in differentiation and unless EPO is present during the critical period, the progenitors will undergo apoptosis. EPO specifically augments the number of circulating erythrocytes by promoting the survival and therefore enabling the proliferation and differentiation o ...
... EPO (EPOR) during specific phases in differentiation and unless EPO is present during the critical period, the progenitors will undergo apoptosis. EPO specifically augments the number of circulating erythrocytes by promoting the survival and therefore enabling the proliferation and differentiation o ...
Lipopolysaccharide modulates neutrophil recruitment and
... activation and dyslipidemia resulting from the aberrant elevated postprandial chylomicron production in metabolic syndrome, as well as the dietary endotoxins, such as LPS associated with them (32, 37, 74). LPS, a critical cell wall component of most gram-negative bacteria, has been identified as the ...
... activation and dyslipidemia resulting from the aberrant elevated postprandial chylomicron production in metabolic syndrome, as well as the dietary endotoxins, such as LPS associated with them (32, 37, 74). LPS, a critical cell wall component of most gram-negative bacteria, has been identified as the ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.