Cleavage furrow formation and ingression during animal cytokinesis
... Cytokinesis is the final act of cell division. In a typical animal mitosis, a cleavage furrow forms at the equatorial cortex after anaphase. This furrow then advances inwards to separate the two daughter cells. Since the early studies of Rappaport more than forty years ago (Rappaport, 1961), it has ...
... Cytokinesis is the final act of cell division. In a typical animal mitosis, a cleavage furrow forms at the equatorial cortex after anaphase. This furrow then advances inwards to separate the two daughter cells. Since the early studies of Rappaport more than forty years ago (Rappaport, 1961), it has ...
Regulation of erythropoiesis
... production of EPO under hypoxia condition by osteoblasts in bone marrow microenvironment is sufficient to drive erythropoiesis; Small molecules that inhibit PHD could pharmacologically activate HIF pathway and rescue anemia (in trial). In patients with renal failure, in addition to hepatocytes, os ...
... production of EPO under hypoxia condition by osteoblasts in bone marrow microenvironment is sufficient to drive erythropoiesis; Small molecules that inhibit PHD could pharmacologically activate HIF pathway and rescue anemia (in trial). In patients with renal failure, in addition to hepatocytes, os ...
Localization of Laminin B1 mRNA in Retinal Ganglion Cells by In
... labeled cells are found in several structures in the eye (Fig. 2, A and B). The lens is strongly labeled. The pigment epithelium also shows intense labeling. The retina itself appears to have no labeled cells (Fig. 2, A-C). Interestingly, many cells located between the lens and retina show strong la ...
... labeled cells are found in several structures in the eye (Fig. 2, A and B). The lens is strongly labeled. The pigment epithelium also shows intense labeling. The retina itself appears to have no labeled cells (Fig. 2, A-C). Interestingly, many cells located between the lens and retina show strong la ...
CASK (LIN2) interacts with Cx43 in wounded skin and their
... In vertebrates, connexin proteins assemble into tightly packed gap junctional channels to connect the cytoplasms of adjacent cells via an aqueous-filled channel. Gap junctions allow the passive diffusion of molecules lower than 1000 Da in size such as ions, amino acids, nutrients and secondary messe ...
... In vertebrates, connexin proteins assemble into tightly packed gap junctional channels to connect the cytoplasms of adjacent cells via an aqueous-filled channel. Gap junctions allow the passive diffusion of molecules lower than 1000 Da in size such as ions, amino acids, nutrients and secondary messe ...
Rebamipide Delivered by Brushite Cement Enhances Osteoblast and Macrophage Proliferation
... resulting in a 73% increase in proliferation at low concentrations, but no additional enhancement in ALP activity compared to control composite leach (group 0). However, the leach from drug loaded composites appears to reduce proliferation with higher Rebamipide concentrations (Group 2–4). This bi ...
... resulting in a 73% increase in proliferation at low concentrations, but no additional enhancement in ALP activity compared to control composite leach (group 0). However, the leach from drug loaded composites appears to reduce proliferation with higher Rebamipide concentrations (Group 2–4). This bi ...
What is bad in cancer is good in the embryo: Importance of EMT in
... explants treated with Rho inhibitors [14]. Although originally shown to be essential for NC delamination and thus the loss of epithelial polarity, a more recent paper indicates that both RhoB and RhoA, through ROCK signaling, act to maintain apicobasal polarity and stabilize N-cadherin in a vinculin ...
... explants treated with Rho inhibitors [14]. Although originally shown to be essential for NC delamination and thus the loss of epithelial polarity, a more recent paper indicates that both RhoB and RhoA, through ROCK signaling, act to maintain apicobasal polarity and stabilize N-cadherin in a vinculin ...
Gelatin fragments block adherence of Candida
... yeast cells to immobilized ECM proteins and to subendothelial ECM is also inhibited by peptides derived from fibronectin, such as RGD, or from collagen, such as GRGESP (Klotz & Smith, 1991). Gelatin is a protein available in large quantities which is tolerated by humans even when given intravenously ...
... yeast cells to immobilized ECM proteins and to subendothelial ECM is also inhibited by peptides derived from fibronectin, such as RGD, or from collagen, such as GRGESP (Klotz & Smith, 1991). Gelatin is a protein available in large quantities which is tolerated by humans even when given intravenously ...
Regulatory roles of cyclin dependent kinase phosphorylation in cell
... on Cdc25 that are recognized by the mpm2 monoclonal antibody. Mpm2-binding phosphoepitopes are generated during mitosis on a number of proteins, including not only Cdc25 but also Weel, suggesting that Plxl may also contribute to Weel hyperphosphorylation in mitosis [23]. These observations reveal th ...
... on Cdc25 that are recognized by the mpm2 monoclonal antibody. Mpm2-binding phosphoepitopes are generated during mitosis on a number of proteins, including not only Cdc25 but also Weel, suggesting that Plxl may also contribute to Weel hyperphosphorylation in mitosis [23]. These observations reveal th ...
Cell Based Therapy for Ocular Surface Reconstruction
... cells (Cultivated Limbal Epithelial TransplantationCLET): The concerns regarding donor site complications prompted the possibility of obtaining smaller biopsy and expanding the cells ex-vivo on a suitable substrate before transplanting them onto the affected eye. Since Pellegrini and co-workers54 fi ...
... cells (Cultivated Limbal Epithelial TransplantationCLET): The concerns regarding donor site complications prompted the possibility of obtaining smaller biopsy and expanding the cells ex-vivo on a suitable substrate before transplanting them onto the affected eye. Since Pellegrini and co-workers54 fi ...
Cryptic O2 –-generating NADPH oxidase in
... and the cells were disrupted by sonication four times for 30 seconds at 10 W output. After a 5 minute centrifugation at 10,000 g, the supernatant fraction was withdrawn and centrifuged at 300,000 g for 30 minutes at 4°C in a TL-100 centrifuge. The supernatant was referred to as cytosol, and the memb ...
... and the cells were disrupted by sonication four times for 30 seconds at 10 W output. After a 5 minute centrifugation at 10,000 g, the supernatant fraction was withdrawn and centrifuged at 300,000 g for 30 minutes at 4°C in a TL-100 centrifuge. The supernatant was referred to as cytosol, and the memb ...
Formulation and Evaluation of Bioadhesive Gels Containing Miconazole Nitrate
... enhancers were shown to increase the amount of miconazole released at an optimum concentration specific for each vehicle, as shown by 1% tween 80 which proved to be superior when incorporated with sodium alginate and carbopol 934 while 3% taurocholic acid was found also to be effective with sodium a ...
... enhancers were shown to increase the amount of miconazole released at an optimum concentration specific for each vehicle, as shown by 1% tween 80 which proved to be superior when incorporated with sodium alginate and carbopol 934 while 3% taurocholic acid was found also to be effective with sodium a ...
Sepsis is a common condition, and more than 19 million cases of
... therapeutic interventions for sepsis (e.g.7,8,9). Attempts to target (and antagonise) single molecules implicated in sepsis have proved futile in clinical trials, reinforcing the notion that therapies that modulate the body’s innate immune response, such as MPLA, may be more likely to demonstrate cl ...
... therapeutic interventions for sepsis (e.g.7,8,9). Attempts to target (and antagonise) single molecules implicated in sepsis have proved futile in clinical trials, reinforcing the notion that therapies that modulate the body’s innate immune response, such as MPLA, may be more likely to demonstrate cl ...
distribution of microtubules in the golgi apparatus of euglena gracilis
... which they belong. The presence of microtubules in the Golgi apparatus is of particular interest since they possibly play a role in the functional processes of the Golgi apparatus. Microtubules would surely add an element of structural rigidity or anisotropy to the Golgi apparatus and could act to p ...
... which they belong. The presence of microtubules in the Golgi apparatus is of particular interest since they possibly play a role in the functional processes of the Golgi apparatus. Microtubules would surely add an element of structural rigidity or anisotropy to the Golgi apparatus and could act to p ...
Low and High Nucleic Acid Content Bacteria: Reality or
... (SSC) and green fluorescence is taken into account. One cluster shows low SSC as well as low green fluorescence and the other one shows high SSC and fluorescence. Based on these observations these two clusters have been given names LNA and HNA bacteria respectively. The majority of studies carried o ...
... (SSC) and green fluorescence is taken into account. One cluster shows low SSC as well as low green fluorescence and the other one shows high SSC and fluorescence. Based on these observations these two clusters have been given names LNA and HNA bacteria respectively. The majority of studies carried o ...
The recovery and purification of fermentation products
... 3. Precise timing of harvesting. 4. pH control after harvesting. 5. Temperature treatment after harvesting. 6. Addition of flocculating agents. 7. Use of enzymes to attack cell walls. It must be remembered that the fermentation and product recovery are integral parts of an overall process. Beca ...
... 3. Precise timing of harvesting. 4. pH control after harvesting. 5. Temperature treatment after harvesting. 6. Addition of flocculating agents. 7. Use of enzymes to attack cell walls. It must be remembered that the fermentation and product recovery are integral parts of an overall process. Beca ...
Nanodimension artificial cells containing a
... to the in vivo system, thus allowing us to confirm the effects and verify the suitable dose for the animal study. In the following in vivo research, the tumor-bearing mice model was established based on B16F10 cells injection, and results showed the artificial cell’ effectiveness in suppressing the ...
... to the in vivo system, thus allowing us to confirm the effects and verify the suitable dose for the animal study. In the following in vivo research, the tumor-bearing mice model was established based on B16F10 cells injection, and results showed the artificial cell’ effectiveness in suppressing the ...
Amyloplasts and Vacuolar Membrane Dynamics in
... Higher plants cannot escape from the place where they germinate and settle, even if the environmental conditions drastically change. Plants have developed many mechanisms during the course of evolution to survive in such circumstances by changing growth direction or architecture of their body shape. ...
... Higher plants cannot escape from the place where they germinate and settle, even if the environmental conditions drastically change. Plants have developed many mechanisms during the course of evolution to survive in such circumstances by changing growth direction or architecture of their body shape. ...
Document
... gliomas, often harboring histone H3K27M mutations and most frequently observed in childhood.47 These tumors have very high mortality and morbidity as effective treatment strategies still do not exist,18,26 despite significant progress in understanding the biological processes that play a role in the ...
... gliomas, often harboring histone H3K27M mutations and most frequently observed in childhood.47 These tumors have very high mortality and morbidity as effective treatment strategies still do not exist,18,26 despite significant progress in understanding the biological processes that play a role in the ...
isolation and characterization of membranes from the cells of maize
... The endomembrane system of eukaryotic cells includes the nuclear envelope, rough and smooth endoplasmic reticulum, Golgi apparatus, plasma membrane and various cytoplasmic vesicles (Northcote, 1971, 1974). Some of the components of the system are joined by structural connexions and they all have a f ...
... The endomembrane system of eukaryotic cells includes the nuclear envelope, rough and smooth endoplasmic reticulum, Golgi apparatus, plasma membrane and various cytoplasmic vesicles (Northcote, 1971, 1974). Some of the components of the system are joined by structural connexions and they all have a f ...
ErbB2/HER2: Its Contribution to Basic Cancer Biology and the
... however, for simplicity, we will use one term “ErbB2” in this article. 2.1 Neu, an oncogene cloned from murine brain tumors The origin of ErbB2/HER2/neu research can be traced back to the 1980s, when virtually all cancer researchers were hunting for novel oncogenes. Cancer researchers, using the too ...
... however, for simplicity, we will use one term “ErbB2” in this article. 2.1 Neu, an oncogene cloned from murine brain tumors The origin of ErbB2/HER2/neu research can be traced back to the 1980s, when virtually all cancer researchers were hunting for novel oncogenes. Cancer researchers, using the too ...
the diversity of plastid - University of Wisconsin Oshkosh
... glaucophyte line of chloroplasts is represented by the muroplasts, primitive walled chloroplasts found in the glaucocystophytic algae. Rhodoplasts represent the red lineage and are the chloroplasts of the red algae. The green lineage gave rise to the plastids of the green algae and members of the Ki ...
... glaucophyte line of chloroplasts is represented by the muroplasts, primitive walled chloroplasts found in the glaucocystophytic algae. Rhodoplasts represent the red lineage and are the chloroplasts of the red algae. The green lineage gave rise to the plastids of the green algae and members of the Ki ...
Cells Producing - The Journal of Immunology
... the Thy1a (Thy1.1) allele and can be recognized easily by flow cytometric analysis using a Thy1.1-specific Ab. Naive Tconv and Treg populations used in this study were confirmed by assessing Foxp3 expression (data not shown). Culture of Tconvs with antiCD3 mAb and APCs did not induce IL-17–producing ...
... the Thy1a (Thy1.1) allele and can be recognized easily by flow cytometric analysis using a Thy1.1-specific Ab. Naive Tconv and Treg populations used in this study were confirmed by assessing Foxp3 expression (data not shown). Culture of Tconvs with antiCD3 mAb and APCs did not induce IL-17–producing ...
Elevated Level of Nuclear Protein Kinase C in
... specific for the o, ß,and 7 isotypes of PKC prepared as described in "Materials and Methods." In intact MCF-7 cells, multidrug-resistant MCF-7/ADR cells showed a markedly en hanced immunoreactivity to PKC compared to that of drugsensitive MCF-7/WT cells (Fig. 1). The most pronounced difference was ...
... specific for the o, ß,and 7 isotypes of PKC prepared as described in "Materials and Methods." In intact MCF-7 cells, multidrug-resistant MCF-7/ADR cells showed a markedly en hanced immunoreactivity to PKC compared to that of drugsensitive MCF-7/WT cells (Fig. 1). The most pronounced difference was ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.