Kohl_Final_after-renumbering_RG-SD-PK - Spiral
... junctional molecules such as cadherins and Cx43. These cells also have important roles in the active secretion and turnover of collagen and other ECM molecules10 and are responsive to hypoxia, cytokines and signalling molecules associated with the inflammatory milieu, such as TGF, tumor necrosis fa ...
... junctional molecules such as cadherins and Cx43. These cells also have important roles in the active secretion and turnover of collagen and other ECM molecules10 and are responsive to hypoxia, cytokines and signalling molecules associated with the inflammatory milieu, such as TGF, tumor necrosis fa ...
Zhang YA, Okada A, Lew CH, McConnell SK
... main, was deleted (GFP–⌬N97, –⌬N250, and –⌬N309: Figs. 4D– 4F) adopted a distribution identical to that of GFP alone, with protein visible in both the cytoplasm and the nucleus. These results are consistent with the hypothesis that the RKQRRER sequence within the homeodomain plays an important role ...
... main, was deleted (GFP–⌬N97, –⌬N250, and –⌬N309: Figs. 4D– 4F) adopted a distribution identical to that of GFP alone, with protein visible in both the cytoplasm and the nucleus. These results are consistent with the hypothesis that the RKQRRER sequence within the homeodomain plays an important role ...
biology and medicine Embryonic stem cell differentiation
... consist of an inner cluster of maturing erythrocytes surrounded by a layer of developing endothelial cells (Haar and Ackerman 1971). The erythroid cells within these blood islands, known as primitive erythrocytes, are distinct from fetal and adult erythrocytes in that they are large, circulate in th ...
... consist of an inner cluster of maturing erythrocytes surrounded by a layer of developing endothelial cells (Haar and Ackerman 1971). The erythroid cells within these blood islands, known as primitive erythrocytes, are distinct from fetal and adult erythrocytes in that they are large, circulate in th ...
Experimental taphonomy of giant sulphur bacteria: implications for
... mucous sheath, in which microbial filaments are still present. Eventually, the sheath disintegrates and diffuses into the surrounding sea water, though sheaths can remain intact for months or years before degradation. ...
... mucous sheath, in which microbial filaments are still present. Eventually, the sheath disintegrates and diffuses into the surrounding sea water, though sheaths can remain intact for months or years before degradation. ...
UVB induced cell cycle checkpoints in an early stage
... was detected within 12 h in the control non-irradiated cells. Cells irradiated in early G1, 4 h after release from G0, showed no S phase entrance for up to 20 h postirradiation (Figure 2). Recovery of G1-to-S phase progression was detected by 24 ± 36 h post irradiation (not shown). To determine the ...
... was detected within 12 h in the control non-irradiated cells. Cells irradiated in early G1, 4 h after release from G0, showed no S phase entrance for up to 20 h postirradiation (Figure 2). Recovery of G1-to-S phase progression was detected by 24 ± 36 h post irradiation (not shown). To determine the ...
Taxol-stabilized Microtubules Can Position the
... positioning, with a subpopulation of relatively stable microtubules interacting with the equatorial cortex to promote furrow formation, and dynamic microtubules at the polar regions helping to suppress ectopic furrowing (Canman et al., 2003). Therefore, microtubule dynamics, rather than their locati ...
... positioning, with a subpopulation of relatively stable microtubules interacting with the equatorial cortex to promote furrow formation, and dynamic microtubules at the polar regions helping to suppress ectopic furrowing (Canman et al., 2003). Therefore, microtubule dynamics, rather than their locati ...
Phospholamban Is Present in Endothelial Cells and Modulates
... vascular tissues.10 –12 Consistent with this observation, we also measured a significant increase in sensitivity to forskolin in endothelium-intact aortas from WT mice. Importantly, this difference in forskolin-mediated relaxation between endothelium-intact and denuded vessels was blunted in aortas ...
... vascular tissues.10 –12 Consistent with this observation, we also measured a significant increase in sensitivity to forskolin in endothelium-intact aortas from WT mice. Importantly, this difference in forskolin-mediated relaxation between endothelium-intact and denuded vessels was blunted in aortas ...
Activation of Lymphocyte Signaling by the R1 Protein of Rhesus
... Expression of a CD8 chimera protein containing the extracellular and transmembrane domains of CD8 fused to the cytoplasmic domain of R1 mobilized intracellular calcium and induced cellular tyrosine phosphorylation in B cells upon stimulation with anti-CD8 antibody. None of the CD8-R1 cytoplasmic del ...
... Expression of a CD8 chimera protein containing the extracellular and transmembrane domains of CD8 fused to the cytoplasmic domain of R1 mobilized intracellular calcium and induced cellular tyrosine phosphorylation in B cells upon stimulation with anti-CD8 antibody. None of the CD8-R1 cytoplasmic del ...
effect of antimetabolite immunosuppressants on flaviviridae
... The decrease in cell growth caused by AZA at higher concen(18, 20), and, because high concentrations of AZA without trations can be prevented by high concentrations of thymi- thymidine does affect Huh7 cell confluency (data not shown), dine (1 mM) . Under these conditions, DNA synthesis is lim- we a ...
... The decrease in cell growth caused by AZA at higher concen(18, 20), and, because high concentrations of AZA without trations can be prevented by high concentrations of thymi- thymidine does affect Huh7 cell confluency (data not shown), dine (1 mM) . Under these conditions, DNA synthesis is lim- we a ...
Gram stain reagents - Bakersfield College
... for staining is important to ensure good results. Remember, you cannot see the material you are working with so you must develop good technique based upon principles. Always start with clean slides using lens paper to clean them. Slides can be made from direct clinical material (a wound, sputum, kne ...
... for staining is important to ensure good results. Remember, you cannot see the material you are working with so you must develop good technique based upon principles. Always start with clean slides using lens paper to clean them. Slides can be made from direct clinical material (a wound, sputum, kne ...
Human Placenta-Derived Adherent Cells: Angiogenic
... Invitrogen, Carlsbad, CA) for 24 hours in order to prepare CM containing factors secreted by PDAC cells. The following day, medium was removed from the HUVEC cultures and replaced with PDAC CM. Additionally, the PDAC cells transwell inserts were placed into the HUVEC multiwell plates to produce a ...
... Invitrogen, Carlsbad, CA) for 24 hours in order to prepare CM containing factors secreted by PDAC cells. The following day, medium was removed from the HUVEC cultures and replaced with PDAC CM. Additionally, the PDAC cells transwell inserts were placed into the HUVEC multiwell plates to produce a ...
to the complete text
... remarkable features of this cell type. As new materials are added to the plasma membrane and the cell wall, work must be done to expand the cell surface. Logic demands that the power for this process must come from turgor because this is the only known source of mechanical stress within the wall tha ...
... remarkable features of this cell type. As new materials are added to the plasma membrane and the cell wall, work must be done to expand the cell surface. Logic demands that the power for this process must come from turgor because this is the only known source of mechanical stress within the wall tha ...
Molecular authenticity of neoplastic and normal lymphocytic leukemia patients
... factors in the microenvironment, multiple experimental models have been reported. However, none of these animal or co-culture systems completely mirrors the in vivo scenario [6]. Nevertheless, the importance of pro-survival influences from stromal-cell derived thioredoxin 1 (Trx1) [7-10], stem-cell ...
... factors in the microenvironment, multiple experimental models have been reported. However, none of these animal or co-culture systems completely mirrors the in vivo scenario [6]. Nevertheless, the importance of pro-survival influences from stromal-cell derived thioredoxin 1 (Trx1) [7-10], stem-cell ...
Polarity and endocytosis: reciprocal regulation
... indicates that the process of endocytosis per se is not completely blocked, and that mutant cells have alternative pathways through which membrane can be internalized. While these alternative pathways are capable of allowing sufficient function for viable cell physiology and division, what is lackin ...
... indicates that the process of endocytosis per se is not completely blocked, and that mutant cells have alternative pathways through which membrane can be internalized. While these alternative pathways are capable of allowing sufficient function for viable cell physiology and division, what is lackin ...
Two-dimensional numerical study of flow
... is used to represent the tether length. θc is the angle between Lc and the x-axis, Fig. 1b. For simplicity, Lc, θc, t, FD and FL shown in later discussions are non-dimensionalized by R, π, 1/k, ρ0k2R4 and ρ0k2R4, respectively. Parameter values used in this study are listed in Table 1. From the data ...
... is used to represent the tether length. θc is the angle between Lc and the x-axis, Fig. 1b. For simplicity, Lc, θc, t, FD and FL shown in later discussions are non-dimensionalized by R, π, 1/k, ρ0k2R4 and ρ0k2R4, respectively. Parameter values used in this study are listed in Table 1. From the data ...
TLR-Dependent Th17 Activation Psoriasis
... of the copy number variation in the b-defensin gene locus (8). These findings suggest that an altered innate defense mechanism and the resulting enhanced IL-23 signaling might initiate psoriasis. Lysosomal cysteine proteases, generally known as the cathepsins (CTSs), exert enzymatic activity under l ...
... of the copy number variation in the b-defensin gene locus (8). These findings suggest that an altered innate defense mechanism and the resulting enhanced IL-23 signaling might initiate psoriasis. Lysosomal cysteine proteases, generally known as the cathepsins (CTSs), exert enzymatic activity under l ...
THYMIC REQUIREMENT FOR CYCLICAL IDIOTYPIC AND
... BALB/c mice. Ascites fluid containing the relevant myeloma protein was obtained by injecting mice intraperitoneally with 0.5 ml of mineral oil (Diamond Drug Incorporated, Westhaven, Conn.) at least 1 wk before an intraperitoneal inoculation of tumor cells. The resulting ascitic fluid was recovered, ...
... BALB/c mice. Ascites fluid containing the relevant myeloma protein was obtained by injecting mice intraperitoneally with 0.5 ml of mineral oil (Diamond Drug Incorporated, Westhaven, Conn.) at least 1 wk before an intraperitoneal inoculation of tumor cells. The resulting ascitic fluid was recovered, ...
B-chronic lymphocytic leukemia (B-CLL) is the most
... miRNAs a role of miR-15a and miR-16 in CLL pathogenesis was also proposed through the upregulation of bcl-2. However, recent reports revealed that significant reduction in miR-15 and/or miR-16 expression levels in CLL was not paralleled by any significant change in bcl-2 . In another recent study us ...
... miRNAs a role of miR-15a and miR-16 in CLL pathogenesis was also proposed through the upregulation of bcl-2. However, recent reports revealed that significant reduction in miR-15 and/or miR-16 expression levels in CLL was not paralleled by any significant change in bcl-2 . In another recent study us ...
Expression of the nidogen-binding site of the laminin γ1 chain
... production of the basement membrane (Smyth et al., 1999), a structure crucial for the normal development of many epithelia (Murray and Edgar, 2000). Results from a multitude of sources (Paulsson et al., 1987; Mann et al., 1988; Aumailley et al., 1989; Fox et al., 1991; Aumailley et al., 1993) sugges ...
... production of the basement membrane (Smyth et al., 1999), a structure crucial for the normal development of many epithelia (Murray and Edgar, 2000). Results from a multitude of sources (Paulsson et al., 1987; Mann et al., 1988; Aumailley et al., 1989; Fox et al., 1991; Aumailley et al., 1993) sugges ...
machen2006
... In contrast to these studies showing apparent intrinsic hyperinflammation in CF cells, Dakin et al. (32) showed that early infection in CF was the likely explanation for the enhanced inflammatory responses in CF lungs. This result was consistent with other in vivo measurements of inflammatory mediat ...
... In contrast to these studies showing apparent intrinsic hyperinflammation in CF cells, Dakin et al. (32) showed that early infection in CF was the likely explanation for the enhanced inflammatory responses in CF lungs. This result was consistent with other in vivo measurements of inflammatory mediat ...
Facultad de Ciencias Tráfico de células dendríticas a través
... 1.2 Morphological characteristics of the lymphatic endothelium The morphological differences that discriminate lymphatic capillaries from their blood counterparts have been reviewed by Mihaela Skobe (Skobe and Detmar, 2000). In summary, the lymphatic vessels present an irregular lumen that is wider ...
... 1.2 Morphological characteristics of the lymphatic endothelium The morphological differences that discriminate lymphatic capillaries from their blood counterparts have been reviewed by Mihaela Skobe (Skobe and Detmar, 2000). In summary, the lymphatic vessels present an irregular lumen that is wider ...
The Cell Membrane - Libreria Universo
... mechanism for transporting ions, certain microbes synthesize small organic molecules called ionophores that transport ions by actually traveling across the membrane. These iono- ...
... mechanism for transporting ions, certain microbes synthesize small organic molecules called ionophores that transport ions by actually traveling across the membrane. These iono- ...
Roles of FGFs as adipokines in adipose tissue development
... and metabolism (Wang et al., 2008; Galic et al., 2010). Although BAT also produces adipokines, the endocrine roles of BAT are needed to determine by further research (Villarroya et al., 2013). Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, ...
... and metabolism (Wang et al., 2008; Galic et al., 2010). Although BAT also produces adipokines, the endocrine roles of BAT are needed to determine by further research (Villarroya et al., 2013). Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.