UNIT 1 – FORCE AND MOTION (SEPUP Force and
... B-1.3 Use scientific instruments to record measurement data in appropriate metric units that reflect the precision and accuracy of each particular instrument. B-1.4 Design a scientific investigation with appropriate methods of control to test a hypothesis (including independent and dependent variabl ...
... B-1.3 Use scientific instruments to record measurement data in appropriate metric units that reflect the precision and accuracy of each particular instrument. B-1.4 Design a scientific investigation with appropriate methods of control to test a hypothesis (including independent and dependent variabl ...
in Murine Mast Cells by Recombinant Stem Cell Factor
... to cellular membranes in response to nanomolar calcium concentrations (21-24). There also exists a family of low molecular weight PLA2 (- 14 kD in size, called group II PLA2) that is released from cells during activation (25-28). Group II PLA2 are present in high quantities in inflammatory sites suc ...
... to cellular membranes in response to nanomolar calcium concentrations (21-24). There also exists a family of low molecular weight PLA2 (- 14 kD in size, called group II PLA2) that is released from cells during activation (25-28). Group II PLA2 are present in high quantities in inflammatory sites suc ...
Comparative assessment of heavy metal removal by
... 1992; Hussein et al., 2001; Hussein et al., 2003). Feasibility studies for large-scale applications demonstrated that, biosorptive processes are more applicable than the bioaccumulative processes, because living systems (active uptake) often require the addition of nutrients and hence increase biolo ...
... 1992; Hussein et al., 2001; Hussein et al., 2003). Feasibility studies for large-scale applications demonstrated that, biosorptive processes are more applicable than the bioaccumulative processes, because living systems (active uptake) often require the addition of nutrients and hence increase biolo ...
... might mediate the P. aeruginosa binding to mucin [24]. The presence of chemotactic factors for P. aeruginosa in mucins from CF patients has been reported by NELSON et aL [25]. However, the observation that both nonmotile and nonchemotactic mutants of P. aeruginosa also adhered to mucin, suggests tha ...
Innate response to human cytomegalovirus pathogenesis of atherosclerosis
... receptors, phosphatidyl serine receptors, thrombospondin receptors, integrins and complement receptors [9]. By contrast, debris generated during necrosis lead to the production of cytokines and pro-inflammatory mediators. MΦ identificate danger signals through Toll-like receptors (TLRs) and other in ...
... receptors, phosphatidyl serine receptors, thrombospondin receptors, integrins and complement receptors [9]. By contrast, debris generated during necrosis lead to the production of cytokines and pro-inflammatory mediators. MΦ identificate danger signals through Toll-like receptors (TLRs) and other in ...
Functional characterization of dI6 interneurons in the neonatal
... genetically defined cell populations play specific roles in the production of locomotor behavior. Clear deficits in the fictive locomotor pattern have been observed in the absence of the V0 (Lanuza et al. 2004) and V1 (Gosgnach et al. 2006) populations, and subsequent experiments have demonstrated c ...
... genetically defined cell populations play specific roles in the production of locomotor behavior. Clear deficits in the fictive locomotor pattern have been observed in the absence of the V0 (Lanuza et al. 2004) and V1 (Gosgnach et al. 2006) populations, and subsequent experiments have demonstrated c ...
circular of information
... information regarding requirements that the donor has not met is included in the summary of records/information provided to the transplant center. The cellular therapy products from such donors are also labeled accordingly. (See Table 2.) Cellular therapy products from a donor with abnormal screenin ...
... information regarding requirements that the donor has not met is included in the summary of records/information provided to the transplant center. The cellular therapy products from such donors are also labeled accordingly. (See Table 2.) Cellular therapy products from a donor with abnormal screenin ...
BIM1 Encodes a Microtubule-binding Protein in Yeast.
... also was found to have more subtle defects in spindle morphology (Trueheart et al., 1987). However, bik1 mutants display synthetic lethality with tubulin mutations (Berlin et al., 1990) as well as mutations in other genes. A particularly interesting genetic characteristic of BIK1 is that overexpress ...
... also was found to have more subtle defects in spindle morphology (Trueheart et al., 1987). However, bik1 mutants display synthetic lethality with tubulin mutations (Berlin et al., 1990) as well as mutations in other genes. A particularly interesting genetic characteristic of BIK1 is that overexpress ...
The Cell Membrane
... proteins serve as (1) channels, which permit the passage of selected ions through the membrane; (2) carriers (or trans porters), which translocate substances across the membrane by binding to them; (3) pumps, which are carriers that split adenosine triphosphate (ATP) and use the energy derived for ...
... proteins serve as (1) channels, which permit the passage of selected ions through the membrane; (2) carriers (or trans porters), which translocate substances across the membrane by binding to them; (3) pumps, which are carriers that split adenosine triphosphate (ATP) and use the energy derived for ...
Guanine Nucleotides Modulate the Effects of Brefeldin A in
... the detailed distribution of the protein in the Golgi region is yet to be defined. Within 30 s of addition of BFA the ll0-kD protein is redistributed from Golgi membrane into a diffuse cytoplasmic distribution. This effect precedes all other morphological changes in the distribution of integral memb ...
... the detailed distribution of the protein in the Golgi region is yet to be defined. Within 30 s of addition of BFA the ll0-kD protein is redistributed from Golgi membrane into a diffuse cytoplasmic distribution. This effect precedes all other morphological changes in the distribution of integral memb ...
Chapter 1 Literature Review
... operative technique, infection, and biological reactions to constituents of the implants. The biological reactions may be mediated by three distinct mechanisms: i) hypersensitivity to metals; ii) foreign body reactions to particulate debris, also known as particle disease, which is mediated by macro ...
... operative technique, infection, and biological reactions to constituents of the implants. The biological reactions may be mediated by three distinct mechanisms: i) hypersensitivity to metals; ii) foreign body reactions to particulate debris, also known as particle disease, which is mediated by macro ...
Anion homeostasis is important for non
... of the major capsid protein VP1, as well as the two minor capsid proteins VP2 and VP3. VP1 forms 72 pentamers, with one copy of either VP2 or VP3 located on the inside of each pentamer. The orthopolyomaviruses also encode agnoprotein, a small hydrophobic multifunctional protein [6,7,22]. While many ...
... of the major capsid protein VP1, as well as the two minor capsid proteins VP2 and VP3. VP1 forms 72 pentamers, with one copy of either VP2 or VP3 located on the inside of each pentamer. The orthopolyomaviruses also encode agnoprotein, a small hydrophobic multifunctional protein [6,7,22]. While many ...
Orthologs of Arabidopsis thaliana stomatal bHLH
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
electrophysiological investigations of the heart of squill a mantis
... The number of impulses in the burst fired by the g.n.t. was related to the interval between the bursts. In any one heart the number was fairly constant over a short time (several minutes) but over a longer period the heart slowed and the number of impulses per burst increased. Fig. 6 illustrates thi ...
... The number of impulses in the burst fired by the g.n.t. was related to the interval between the bursts. In any one heart the number was fairly constant over a short time (several minutes) but over a longer period the heart slowed and the number of impulses per burst increased. Fig. 6 illustrates thi ...
Chapter Two Line Title Here and Chapter Title Here and Here
... 1. The major functions of connective tissue are binding and support, protection, insulation, storing fuel, and transporting substances in the body. B. Common Characteristics of Connective Tissue (p. 127) 1. All connective tissue arises from an embryonic tissue called mesenchyme. 2. Connective tissue ...
... 1. The major functions of connective tissue are binding and support, protection, insulation, storing fuel, and transporting substances in the body. B. Common Characteristics of Connective Tissue (p. 127) 1. All connective tissue arises from an embryonic tissue called mesenchyme. 2. Connective tissue ...
Diazonamide A and a Synthetic Structural Analog
... Natural Products Branch, DTP, National Cancer Institute. The compound was evaluated in the DTP drug screen, and analysis by the COMPARE algorithm of the resulting differential cytotoxicity pattern (Paull et al., 1992) indicated that diazonamide A was probably a tubulin-active agent. Cells treated wi ...
... Natural Products Branch, DTP, National Cancer Institute. The compound was evaluated in the DTP drug screen, and analysis by the COMPARE algorithm of the resulting differential cytotoxicity pattern (Paull et al., 1992) indicated that diazonamide A was probably a tubulin-active agent. Cells treated wi ...
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... liver takes central position in the metabolization of xenobiotics and drugs, this organ most oftenly is subjected to injuries [2, 3]. The leading mechanisms of ...
... liver takes central position in the metabolization of xenobiotics and drugs, this organ most oftenly is subjected to injuries [2, 3]. The leading mechanisms of ...
MyoD as a gatekeeper to cell cycle progression
... Movement through the cell cycle is a highly coordinated process. A major mechanism of regulating this progression is the timely transcriptional activation of genes involved in each phase of the cell cycle. During development, MyoD directs cells fated for myoblast lineage to exit the cell cycle and b ...
... Movement through the cell cycle is a highly coordinated process. A major mechanism of regulating this progression is the timely transcriptional activation of genes involved in each phase of the cell cycle. During development, MyoD directs cells fated for myoblast lineage to exit the cell cycle and b ...
Mechanisms of convergence and extension by cell intercalation
... Keller 1984; Keller et al. 1991a,b). Convergence can be coupled directly to extension with conservation of tissue volume, the decrease in width accounted for by a proportional increase in length (¢gure 1a). More often, however, convergence produces thickening as well as lengthening, the proportion o ...
... Keller 1984; Keller et al. 1991a,b). Convergence can be coupled directly to extension with conservation of tissue volume, the decrease in width accounted for by a proportional increase in length (¢gure 1a). More often, however, convergence produces thickening as well as lengthening, the proportion o ...
Epithelial-Mesenchymal Transition in Pancreatic Carcinoma
... that the type I receptors ALK1, ALK2, and ALK5 have distinct and sometimes opposing functions: Whereas, for example, the principal ALK5 receptor mediates EMT, ALK1 can counteract this effect [17]. Moreover, the TGF signal can be relayed in a non-canonical, i.e., SMAD-independent pathway, which may ...
... that the type I receptors ALK1, ALK2, and ALK5 have distinct and sometimes opposing functions: Whereas, for example, the principal ALK5 receptor mediates EMT, ALK1 can counteract this effect [17]. Moreover, the TGF signal can be relayed in a non-canonical, i.e., SMAD-independent pathway, which may ...
The different shapes of cocci
... single site of centripetal septal synthesis, with gradual splitting of the septum feeding the peripheral growth (Higgins & Shockman, 1970). However, careful measurements of the septal and peripheral wall surface area showed that the latter was growing faster than allowed by septal splitting alone. A ...
... single site of centripetal septal synthesis, with gradual splitting of the septum feeding the peripheral growth (Higgins & Shockman, 1970). However, careful measurements of the septal and peripheral wall surface area showed that the latter was growing faster than allowed by septal splitting alone. A ...
The Analysis of Plant Growth - Plant Physiology and Development
... To characterize the local expansion rate, we must consider the growth velocities at the apical and basal ends of a small segment of tissue. If the apical end of the segment is moving faster than the basal end, the segment is elongating. The velocity difference, divided by the segment length, gives t ...
... To characterize the local expansion rate, we must consider the growth velocities at the apical and basal ends of a small segment of tissue. If the apical end of the segment is moving faster than the basal end, the segment is elongating. The velocity difference, divided by the segment length, gives t ...
Activation of protein phosphatase 2A in FLT3+ acute myeloid
... [8, 9], and therefore represent important therapeutic targets. Several tyrosine kinase inhibitors (TKIs) targeting FLT3 have been investigated in clinical trials, including CEP-701, PKC412, sorafenib and AC220. As single agents in AML trials these were disappointing with shortterm and/or partial rem ...
... [8, 9], and therefore represent important therapeutic targets. Several tyrosine kinase inhibitors (TKIs) targeting FLT3 have been investigated in clinical trials, including CEP-701, PKC412, sorafenib and AC220. As single agents in AML trials these were disappointing with shortterm and/or partial rem ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.