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... DON interferes with the synthesis of GAG and glycoproteins by inhibiting the glutamine dependent conversion of fructose-6-phosphate to glucosaminophosphate (Ghosh et ah 1960; Telser et ah 1965). DON also combines irreversibly with the enzyme necessary for purine nucleoside synthesis (Buchanan, 1973) ...
... DON interferes with the synthesis of GAG and glycoproteins by inhibiting the glutamine dependent conversion of fructose-6-phosphate to glucosaminophosphate (Ghosh et ah 1960; Telser et ah 1965). DON also combines irreversibly with the enzyme necessary for purine nucleoside synthesis (Buchanan, 1973) ...
The L5 epitope: an early marker for neural induction in the chick
... Hensen's node from a donor embryo. As controls, we used either: two other IgM-secreting hybridoma cell lines, whose antibodies recognise cell surface antigens that are also present at the same stages of development in all cells (4B5; Norris, 1989) or in subsets of cells (HNK1; Canning and Stern, 198 ...
... Hensen's node from a donor embryo. As controls, we used either: two other IgM-secreting hybridoma cell lines, whose antibodies recognise cell surface antigens that are also present at the same stages of development in all cells (4B5; Norris, 1989) or in subsets of cells (HNK1; Canning and Stern, 198 ...
Plasmodesmata-Mediated Cell-to-Cell Communication in the Shoot
... specify their fates [18]. Around twenty years ago, the first mobile signal moving between cells via PD, the homeodomain (HD) TF KNOTTED1 (KN1), was discovered in maize. KN1 is expressed in the L2 layers of the maize SAM, but KN1 protein moves into the L1 [19]. The KN1 homologs in Arabidopsis, SHOOT ...
... specify their fates [18]. Around twenty years ago, the first mobile signal moving between cells via PD, the homeodomain (HD) TF KNOTTED1 (KN1), was discovered in maize. KN1 is expressed in the L2 layers of the maize SAM, but KN1 protein moves into the L1 [19]. The KN1 homologs in Arabidopsis, SHOOT ...
Basophils are inept at promoting human Th17 responses
... Quentin Yvelines, France). Results are expressed in kU/L and the admitted ...
... Quentin Yvelines, France). Results are expressed in kU/L and the admitted ...
A Model for Cell Proliferation in a Developing Organism
... Proliferation. A cell is selected uniformly at random. If the cell at site i is selected, it moves to site i + 1 pushing all cells to the right of it up by one. A new unmarked cell now occupies site i. Times between proliferation events are iid exp(λ). Equivalently. You can think of independent homo ...
... Proliferation. A cell is selected uniformly at random. If the cell at site i is selected, it moves to site i + 1 pushing all cells to the right of it up by one. A new unmarked cell now occupies site i. Times between proliferation events are iid exp(λ). Equivalently. You can think of independent homo ...
Monitoring metabolic responses to chemotherapy initiator mass spectrometry (NIMS) imaging
... micro-dissection/extraction methods, adding a new dimension for tracking both substrates and metabolic products [19-21]. NIMS can also be used to measure metabolites in single cells [15], raising the possibility that this method might be useful for characterizing tumor drug responses with high resol ...
... micro-dissection/extraction methods, adding a new dimension for tracking both substrates and metabolic products [19-21]. NIMS can also be used to measure metabolites in single cells [15], raising the possibility that this method might be useful for characterizing tumor drug responses with high resol ...
New type of snRNP containing nuclear bodies in plant cells
... The introduction of immunodetection and in situ hybridization techniques has contributed to a better understanding of intracellular distribution of macromolecules involved in pre-mRNA splicing. In animal cell nuclei the splicing system machinery has been found to be linked to at least several struct ...
... The introduction of immunodetection and in situ hybridization techniques has contributed to a better understanding of intracellular distribution of macromolecules involved in pre-mRNA splicing. In animal cell nuclei the splicing system machinery has been found to be linked to at least several struct ...
Superparamagnetic nanoparticles for biomedical applications
... the further use of nanoparticles in-vivo and in-vitro. The potential toxicity of such material is not only related to their nanosize nature but especially to their surface properties, which is the determining factor for cellular uptake and cytotoxicity, whereas the type of particle does not seem to ...
... the further use of nanoparticles in-vivo and in-vitro. The potential toxicity of such material is not only related to their nanosize nature but especially to their surface properties, which is the determining factor for cellular uptake and cytotoxicity, whereas the type of particle does not seem to ...
Induction of somatic embryogenesis as an example of stress
... review of the signal transduction during oxidative stress, Vranová et al. (2002) inferred that while cell-cycle progression is under negative control of ROS, H2O2 stimulates SE. According these authors, the role of ROS in plant growth and development requires further investigation. H2O2 is a well-kn ...
... review of the signal transduction during oxidative stress, Vranová et al. (2002) inferred that while cell-cycle progression is under negative control of ROS, H2O2 stimulates SE. According these authors, the role of ROS in plant growth and development requires further investigation. H2O2 is a well-kn ...
multiple functions The ADAMs family of metalloproteases
... 19, 22, 23, 28, and 33) show a more broad somatic distribution. Yet, there are clear differences in the pattern of expression of these enzymes (Table 1). ADAMs 9, 12, and 19 were originally cloned from myoblasts (Yagami-Hiromasa et al. 1995), but have been shown subsequently to be more broadly expre ...
... 19, 22, 23, 28, and 33) show a more broad somatic distribution. Yet, there are clear differences in the pattern of expression of these enzymes (Table 1). ADAMs 9, 12, and 19 were originally cloned from myoblasts (Yagami-Hiromasa et al. 1995), but have been shown subsequently to be more broadly expre ...
Plasma Membrane Depolarization Induced by
... et al., 1999; Zingarelli et al., 1999; Kurkdjian et al., 2000). These depolarizations are due to modifications of plasma membrane ion channel activities. Blue light and cold stress activate anion channels following a Ca21-dependent pathway (Cho and Spalding, 1996; Lewis et al., 1997). Nod factors in ...
... et al., 1999; Zingarelli et al., 1999; Kurkdjian et al., 2000). These depolarizations are due to modifications of plasma membrane ion channel activities. Blue light and cold stress activate anion channels following a Ca21-dependent pathway (Cho and Spalding, 1996; Lewis et al., 1997). Nod factors in ...
Thesis - KI Open Archive
... fight of prolonging a patient’s life the quality of life is to some extent put aside. It is important not to forget that we are dealing with patients who desire a better quality of life above all. The dream of personalized medicine is to adjust therapy so that the right drug is given to the right pa ...
... fight of prolonging a patient’s life the quality of life is to some extent put aside. It is important not to forget that we are dealing with patients who desire a better quality of life above all. The dream of personalized medicine is to adjust therapy so that the right drug is given to the right pa ...
regulates cortical cell migration out of the
... along actin stress fibres, except at their ends, suggesting colocalization with F-actin (fibre-like); second, a punctate distribution in the cytoplasm was observed, which was distinct from that of F-actin (punctate). Some cells had a mixture of both patterns. These patterns were dependent largely on ...
... along actin stress fibres, except at their ends, suggesting colocalization with F-actin (fibre-like); second, a punctate distribution in the cytoplasm was observed, which was distinct from that of F-actin (punctate). Some cells had a mixture of both patterns. These patterns were dependent largely on ...
Cells 1.2
... • The Golgi apparatus gathers simple molecules and combines them to make molecules that are more complex. • It then takes those big molecules, packages them in vesicles, and either stores them for later use or sends them out of the cell. • It is also the organelle that builds lysosomes (cell ...
... • The Golgi apparatus gathers simple molecules and combines them to make molecules that are more complex. • It then takes those big molecules, packages them in vesicles, and either stores them for later use or sends them out of the cell. • It is also the organelle that builds lysosomes (cell ...
Conservation of inner nuclear membrane targeting sequences in
... European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, Netherlands; bDepartments of Biochemistry and Pediatric Oncology, Erasmus MC/Sophia, 3015 CN Rotterdam, Netherlands; cDepartment of Experimental Hematology, Univers ...
... European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, Netherlands; bDepartments of Biochemistry and Pediatric Oncology, Erasmus MC/Sophia, 3015 CN Rotterdam, Netherlands; cDepartment of Experimental Hematology, Univers ...
Genetic Block of Outer Plaque Morphogenesis at the Second Meiotic
... outer plaques were detected at both poles at stage I, may correspond to a minor fraction producing three-spored asci. Therefore, we conclude that the genetic block caused by the hfdl-1 mutation at 29 OC affects the morphogenesis of outer plaques and prospore wall membranes at the non-sister poles of ...
... outer plaques were detected at both poles at stage I, may correspond to a minor fraction producing three-spored asci. Therefore, we conclude that the genetic block caused by the hfdl-1 mutation at 29 OC affects the morphogenesis of outer plaques and prospore wall membranes at the non-sister poles of ...
cellular and subcellular mechanisms of cardiac pacemaker oscillations
... tonus changes and the local potentials are probably manifestations of a more fundamental process, a fluctuation in resting metabolism. The mechanical changes are weak and hardly play any role as such. Their chief interest lies in their relation to the automaticity and rhythmicity of the muscle. It m ...
... tonus changes and the local potentials are probably manifestations of a more fundamental process, a fluctuation in resting metabolism. The mechanical changes are weak and hardly play any role as such. Their chief interest lies in their relation to the automaticity and rhythmicity of the muscle. It m ...
Progression Liver Modulates Severe Malaria Disease in the
... a Plasmodium-specific apicoplast protein (17). However, unlike vaccine-like sterilizing immunity induced by attenuated strains, few studies have examined very early cellular immune responses associated with parasite attenuation and their roles in protection from cerebral pathology. One study demonst ...
... a Plasmodium-specific apicoplast protein (17). However, unlike vaccine-like sterilizing immunity induced by attenuated strains, few studies have examined very early cellular immune responses associated with parasite attenuation and their roles in protection from cerebral pathology. One study demonst ...
Regulated protein degradation controls PKA function and cell
... However, at later times, multiple domains partially fuse, leading to the formation of the large, aberrant aggregation streams and aggregates (Fig. 2D; data not shown). In wild-type strains, the mounds initiate a rotary movement, which leads to tip formation after ∼1 h (Rietdorf et al. 1996; Sukumara ...
... However, at later times, multiple domains partially fuse, leading to the formation of the large, aberrant aggregation streams and aggregates (Fig. 2D; data not shown). In wild-type strains, the mounds initiate a rotary movement, which leads to tip formation after ∼1 h (Rietdorf et al. 1996; Sukumara ...
zjawisko oddzia*ywania allelopatycznego sinic i glonów w
... on target organisms. In this work we have shown for the first time that the addition of cellfree filtrate from Baltic N. spumigena and Synechococcus sp. cultures had negative impact on growth and cell morphology of O. submarina. The greatest decrease of growth of O. submarina was observed after the ...
... on target organisms. In this work we have shown for the first time that the addition of cellfree filtrate from Baltic N. spumigena and Synechococcus sp. cultures had negative impact on growth and cell morphology of O. submarina. The greatest decrease of growth of O. submarina was observed after the ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.