PDF - Impact Journals
... expression levels of galectin-1 vary in different kinds of tumors. Some cancerous cells with high levels of endogenous galectin-1 expression, such as nonsmall cell lung cancer (NSCLC) cells, have relative high potentials of anti-chemotherapy. Suppression of galectin-1 sensitizes the NSCLC cells to p ...
... expression levels of galectin-1 vary in different kinds of tumors. Some cancerous cells with high levels of endogenous galectin-1 expression, such as nonsmall cell lung cancer (NSCLC) cells, have relative high potentials of anti-chemotherapy. Suppression of galectin-1 sensitizes the NSCLC cells to p ...
Calcium channel dynamics limit synaptic release in response to prosthetic... sinusoidal waveforms
... that the passive membrane properties of bipolar cells may act to lowpass filter the applied stimulus (Gerhardt et al 2010). This suggests that membrane potential is modulated more strongly at low stimulus frequencies. In addition, while several different types of voltage-gated ion channels have been ...
... that the passive membrane properties of bipolar cells may act to lowpass filter the applied stimulus (Gerhardt et al 2010). This suggests that membrane potential is modulated more strongly at low stimulus frequencies. In addition, while several different types of voltage-gated ion channels have been ...
Anion homeostasis is important for non
... of the major capsid protein VP1, as well as the two minor capsid proteins VP2 and VP3. VP1 forms 72 pentamers, with one copy of either VP2 or VP3 located on the inside of each pentamer. The orthopolyomaviruses also encode agnoprotein, a small hydrophobic multifunctional protein [6,7,22]. While many ...
... of the major capsid protein VP1, as well as the two minor capsid proteins VP2 and VP3. VP1 forms 72 pentamers, with one copy of either VP2 or VP3 located on the inside of each pentamer. The orthopolyomaviruses also encode agnoprotein, a small hydrophobic multifunctional protein [6,7,22]. While many ...
Stamen Structure and Function
... 1998; Amagai et al., 2003; Zik and Irish, 2003). Some of these studies have manipulated B and/or C class genes themselves to help identify their targets; these experiments are discussed in more detail below. Proteomics analysis also has been used to compare and identify proteins extracted from rice ...
... 1998; Amagai et al., 2003; Zik and Irish, 2003). Some of these studies have manipulated B and/or C class genes themselves to help identify their targets; these experiments are discussed in more detail below. Proteomics analysis also has been used to compare and identify proteins extracted from rice ...
Here - Dipartimento di Scienze Chimiche e Farmaceutiche
... absorbing near-infrared (NIR) light, that we have recently developed and characterized as viable solutions to critical issues in tissue repair and drug delivery applications. Laser-assisted tissue repair or laser welding has been proposed to close chronic accidental and surgical wounds. Typically, l ...
... absorbing near-infrared (NIR) light, that we have recently developed and characterized as viable solutions to critical issues in tissue repair and drug delivery applications. Laser-assisted tissue repair or laser welding has been proposed to close chronic accidental and surgical wounds. Typically, l ...
Phylogenomics demonstrates that breviate flagellates are related to
... that B. anathema is sister to the Amoebozoa with the ancyromonads sister to Opisthokonta þ apusomonads (OA) [21], but these results were again compromised by missing data for B. anathema. Most recently, a 30-protein phylogeny showed a BA clade with weak support that could not be conclusively placed ...
... that B. anathema is sister to the Amoebozoa with the ancyromonads sister to Opisthokonta þ apusomonads (OA) [21], but these results were again compromised by missing data for B. anathema. Most recently, a 30-protein phylogeny showed a BA clade with weak support that could not be conclusively placed ...
Cell-based therapies for amyotrophic lateral sclerosis/motor neuron
... When the person presents with both upper and lower motor neuron signs, the disease is known as ALS, which is the most common form of MND. The terms PLS and PMA are applied when the initial presentation reflects only upper motor neuron involvement or only lower motor neuron involvement, respectively. ...
... When the person presents with both upper and lower motor neuron signs, the disease is known as ALS, which is the most common form of MND. The terms PLS and PMA are applied when the initial presentation reflects only upper motor neuron involvement or only lower motor neuron involvement, respectively. ...
Neurogenesis in Postnatal Mouse Dorsal Root Ganglia
... All efforts were made to minimize animal suffering and to reduce the number of animals used. DRG from early postnatal (day 1 or 2) male/female CD1 mice were extracted, minced, and then enzymatically dissociated using 1% trypsin (Gibco) and DNase (10 mg/ml; Boehringer Mannheim) added to Ham’s F14 med ...
... All efforts were made to minimize animal suffering and to reduce the number of animals used. DRG from early postnatal (day 1 or 2) male/female CD1 mice were extracted, minced, and then enzymatically dissociated using 1% trypsin (Gibco) and DNase (10 mg/ml; Boehringer Mannheim) added to Ham’s F14 med ...
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1
... mRNA levels in DFO-treated cells was statistically significant, another experiment was performed in which cells were treated for 20 hours with either 100 M DFO or sterile water as a control. The mean FPN1 mRNA level in DFO-treated cells was 23%⫾ 5% (⫾ SE, n ⫽ 4) lower than control (P ⫽ .012). For c ...
... mRNA levels in DFO-treated cells was statistically significant, another experiment was performed in which cells were treated for 20 hours with either 100 M DFO or sterile water as a control. The mean FPN1 mRNA level in DFO-treated cells was 23%⫾ 5% (⫾ SE, n ⫽ 4) lower than control (P ⫽ .012). For c ...
08_Nasal Drug Delivery
... The epithelial tissue within the nasal cavity is relatively highly vascularized, and thus provides a potential conduit for drug delivery The cellular makeup of the nasal epithelial tissue consists mainly of ciliated columnar cells, non-ciliated columnar cells, goblet cells and basal cells, with the ...
... The epithelial tissue within the nasal cavity is relatively highly vascularized, and thus provides a potential conduit for drug delivery The cellular makeup of the nasal epithelial tissue consists mainly of ciliated columnar cells, non-ciliated columnar cells, goblet cells and basal cells, with the ...
Humoral Immune Responses to Epstein-Barr virus encoded Tumor Associated Proteins and
... different techniques, such as ELISA, immunoblot, and migration inhibition assays (4, 26, 30, 31, 36, 42, 45). Previous studies indicated that LMP1 is a protein with a low immunogenicity for the humoral immune response in humans. In NPC only 7.5% (3/40) patients had low serum levels of LMP1 directed ...
... different techniques, such as ELISA, immunoblot, and migration inhibition assays (4, 26, 30, 31, 36, 42, 45). Previous studies indicated that LMP1 is a protein with a low immunogenicity for the humoral immune response in humans. In NPC only 7.5% (3/40) patients had low serum levels of LMP1 directed ...
The Vacuolar Proton-Cation Exchanger EcNHX1
... wall-localized proteins, and other defense constituents (Tsunezuka et al., 2005; Truman et al., 2007). This complexity is based on widely ramified signal cascades that use ubiquitous intermediates such as jasmonates (Blechert et al., 1995; Memelink et al., 2001), calcium ions, and salicylates and are ...
... wall-localized proteins, and other defense constituents (Tsunezuka et al., 2005; Truman et al., 2007). This complexity is based on widely ramified signal cascades that use ubiquitous intermediates such as jasmonates (Blechert et al., 1995; Memelink et al., 2001), calcium ions, and salicylates and are ...
The origins, function, and regulation of T follicular helper cells
... Downloaded from on May 2, 2017 ...
... Downloaded from on May 2, 2017 ...
Mast cells and basophils in acquired immunity
... mature mast cells can be very long-lived and can retain their ability to proliferate under certain conditions7'14. Mast cells are found particularly around blood vessels, in close proximity to peripheral nerves, and beneath epithelial surfaces that are exposed to the external environment, such as th ...
... mature mast cells can be very long-lived and can retain their ability to proliferate under certain conditions7'14. Mast cells are found particularly around blood vessels, in close proximity to peripheral nerves, and beneath epithelial surfaces that are exposed to the external environment, such as th ...
Derivation of naïve human embryonic stem cells
... hESCs will likely allow increased developmental potential and a more accurate correlation to mESC data. It has been reported that human induced pluripotent cells (h-iPSCs) can be maintained in the naïve state if the pluripotency-inducing transgenes are not silenced (5). Only recently have hESCs been ...
... hESCs will likely allow increased developmental potential and a more accurate correlation to mESC data. It has been reported that human induced pluripotent cells (h-iPSCs) can be maintained in the naïve state if the pluripotency-inducing transgenes are not silenced (5). Only recently have hESCs been ...
Evaluation of cell membrane integrity as a potential antimicrobial
... Bacterial cell membranes can be used as a target for the development of new antibacterial drugs. Many plants produce secondary metabolites which contain a steroid or triterpernoid aglycon attached to one or more sugar chains that exhibit cell membrane permeabilizing properties [11]. Permeability enh ...
... Bacterial cell membranes can be used as a target for the development of new antibacterial drugs. Many plants produce secondary metabolites which contain a steroid or triterpernoid aglycon attached to one or more sugar chains that exhibit cell membrane permeabilizing properties [11]. Permeability enh ...
PDF
... restricted area of extraordinarily rapid cell proliferation within the primary ectoderm (proliferative zone or centre) generates cells which, by expansion forces cause a considerable mass of cells to migrate through the primitive streak (Snow, 1976A, b, 1977). The primitive streak can be regarded as ...
... restricted area of extraordinarily rapid cell proliferation within the primary ectoderm (proliferative zone or centre) generates cells which, by expansion forces cause a considerable mass of cells to migrate through the primitive streak (Snow, 1976A, b, 1977). The primitive streak can be regarded as ...
Plastid degeneration in Tillandsia (Bromeliaceae) provides
... cells are present in the cytoplasm, at the interface of cytoplasm and vacuole, and inside vacuoles. This suggests that they become transported from the cytoplasm to the vacuole. The function of plant MLBs thus seems transfer of cellular membranes to the vacuole. Although it is often impossible to di ...
... cells are present in the cytoplasm, at the interface of cytoplasm and vacuole, and inside vacuoles. This suggests that they become transported from the cytoplasm to the vacuole. The function of plant MLBs thus seems transfer of cellular membranes to the vacuole. Although it is often impossible to di ...
Production of fibronectin and collagen types I and III by chick embryo
... embryonic organs have suggested that the extracellular matrix (ECM) might play an important role in epithelial-mesenchymal interactions (Grobstein, 1967; Slavkin and Greulich, 1975). Dermal-epidermal recombination experiments have shown that the development of skin and cutaneous appendages in the am ...
... embryonic organs have suggested that the extracellular matrix (ECM) might play an important role in epithelial-mesenchymal interactions (Grobstein, 1967; Slavkin and Greulich, 1975). Dermal-epidermal recombination experiments have shown that the development of skin and cutaneous appendages in the am ...
Allogeneic T regulatory cell–mediated
... Treg cells in patients undergoing human leukocyte antigen– matched allogeneic bone marrow transplantation.24 Thus, there is heightened interest in the basis by which allogeneic Treg cells mediate transplantation tolerance. ...
... Treg cells in patients undergoing human leukocyte antigen– matched allogeneic bone marrow transplantation.24 Thus, there is heightened interest in the basis by which allogeneic Treg cells mediate transplantation tolerance. ...
Dual mode of paraxial mesoderm formation during chick gastrulation
... mesoderm. In double- (Fig. 1d) or single-graft (Fig. 1 i and l) experiments analyzed after 24 h, cells from the 90% level of the streak mostly gave rise to cells in medial somites from the anterior level of the somitic region to the tail bud (SI Table 1; Fig. 1 e, g, and j). In contrast, grafts of m ...
... mesoderm. In double- (Fig. 1d) or single-graft (Fig. 1 i and l) experiments analyzed after 24 h, cells from the 90% level of the streak mostly gave rise to cells in medial somites from the anterior level of the somitic region to the tail bud (SI Table 1; Fig. 1 e, g, and j). In contrast, grafts of m ...
Neuron-to-Cell Spread of Pseudorabies Virus in a
... were carefully harvested by scraping the bottom of the dish using the pointed end of a gel-loading tip. The cells and medium were then pooled, freeze-thawed, and titered on PK15 cells. Studying axon-mediated infection of neuronal cell bodies. Briefly, neurons were grown and cultured as described in ...
... were carefully harvested by scraping the bottom of the dish using the pointed end of a gel-loading tip. The cells and medium were then pooled, freeze-thawed, and titered on PK15 cells. Studying axon-mediated infection of neuronal cell bodies. Briefly, neurons were grown and cultured as described in ...
Inhibition of Nitric Oxide Production Is Associated
... X lo6) with or without AKR spleen cells (20 X IO6) to assess the effect of L-NMA in a syngeneic transplant model. Sratisficat analysis. Data are reported as mean values -C 1 SD. Descriptive statistics for weight profilesare reported as group means. The group mean weights were based on decreasing num ...
... X lo6) with or without AKR spleen cells (20 X IO6) to assess the effect of L-NMA in a syngeneic transplant model. Sratisficat analysis. Data are reported as mean values -C 1 SD. Descriptive statistics for weight profilesare reported as group means. The group mean weights were based on decreasing num ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.