Cell Differentiation for the Regulation of Thymocyte and Th2 Distinct
... GATA-3 is a transcription factor, with two N-terminal transactivation domains and two C2-C2 C-terminal zinc fingers (11). The family of GATA transcription factors includes six mammalian members, GATA-1 through GATA-6, which bind a canonical GATA motif (12, 13). Although the zinc finger regions of al ...
... GATA-3 is a transcription factor, with two N-terminal transactivation domains and two C2-C2 C-terminal zinc fingers (11). The family of GATA transcription factors includes six mammalian members, GATA-1 through GATA-6, which bind a canonical GATA motif (12, 13). Although the zinc finger regions of al ...
Primordial germ cells in the mouse embryo during
... Embryos from which the cluster area has been removed at the 7-day stage are devoid of PGCs after culture for 48 h, whereas the excised tissue is rich in PGCs. We argue that the cells in the cluster are indeed primordial germ cells, at a stage significantly earlier than any reported previously. This ...
... Embryos from which the cluster area has been removed at the 7-day stage are devoid of PGCs after culture for 48 h, whereas the excised tissue is rich in PGCs. We argue that the cells in the cluster are indeed primordial germ cells, at a stage significantly earlier than any reported previously. This ...
Biology inside cover Mod2.indd
... These materials have been published jointly by the Commonwealth of Learning and the partner Ministries and institutions. All rights are reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form, or by any means, electronic or mechanical, includ ...
... These materials have been published jointly by the Commonwealth of Learning and the partner Ministries and institutions. All rights are reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form, or by any means, electronic or mechanical, includ ...
The differentiation in vitro of the neural crest cells of the
... by 6 days in culture were particularly CA-positive (Fig. 7A, B). As culture proceeded, the number of CA-positive clumps increased. Some of the clumps possessed axon-like processes. The ganglion-like structures randomly distributed on the epithelial sheet and in the surrounding outgrowth. The differe ...
... by 6 days in culture were particularly CA-positive (Fig. 7A, B). As culture proceeded, the number of CA-positive clumps increased. Some of the clumps possessed axon-like processes. The ganglion-like structures randomly distributed on the epithelial sheet and in the surrounding outgrowth. The differe ...
3 - Rudner Lab - Harvard University
... to become activated. A similar conclusion was reached from molecular genetic studies of the gene that is responsible for the characteristic brown pigment of spores. Sporulation mutants were classically identified by their failure to produce this brown pigment. When it emerged that the appearance of ...
... to become activated. A similar conclusion was reached from molecular genetic studies of the gene that is responsible for the characteristic brown pigment of spores. Sporulation mutants were classically identified by their failure to produce this brown pigment. When it emerged that the appearance of ...
BE WHEN THEY GROW UP? Lessons from Epidermal Patterning in
... transcription factors. Second, the timing and location of differentiation is often regulated by both long-range hormonal signals and local cell-cell signaling. Third, differentiating cells often either stop cycling mitotically or enter a modified cell cycle. The plant epidermis is an excellent tissu ...
... transcription factors. Second, the timing and location of differentiation is often regulated by both long-range hormonal signals and local cell-cell signaling. Third, differentiating cells often either stop cycling mitotically or enter a modified cell cycle. The plant epidermis is an excellent tissu ...
AP Bio Summer Assignment 2016
... As you clean your room up, what happens to the entropy of the universe? ...
... As you clean your room up, what happens to the entropy of the universe? ...
DNA-protein interactions in T. annulata
... a differentiation step that is common to different apicomplexan life cycles. We have studied this event in Theileria annulata, an apicomplexan parasite of bovines. In vivo the macroschizont stage of Theileria resides within the bovine leukocyte and induces host cell proliferation (Hulliger, 1965). F ...
... a differentiation step that is common to different apicomplexan life cycles. We have studied this event in Theileria annulata, an apicomplexan parasite of bovines. In vivo the macroschizont stage of Theileria resides within the bovine leukocyte and induces host cell proliferation (Hulliger, 1965). F ...
Transfer of vesicles from Schwann cells to axons: a novel
... in axons by endocytosis. Nevertheless, the molecular mechanism for ribosomal transfer after axonal damage and during axonal regeneration has not been disclosed yet. Considering that SC exosomes diameter varies between 50 and 120 nm (Lopez-Verrilli M. A., and Court F. A., unpublished results), only a ...
... in axons by endocytosis. Nevertheless, the molecular mechanism for ribosomal transfer after axonal damage and during axonal regeneration has not been disclosed yet. Considering that SC exosomes diameter varies between 50 and 120 nm (Lopez-Verrilli M. A., and Court F. A., unpublished results), only a ...
BDV
... Gene ontology (GO) categories ---Membrane proteins and immune response BDV enters cells by plasma membrane fusion. Remarkably, it replicates in the nucleus of the infected cell, requiring nucleocytoplasmic trafficking of BDV macromolecules. As these processes intimately involve the plasma and nucl ...
... Gene ontology (GO) categories ---Membrane proteins and immune response BDV enters cells by plasma membrane fusion. Remarkably, it replicates in the nucleus of the infected cell, requiring nucleocytoplasmic trafficking of BDV macromolecules. As these processes intimately involve the plasma and nucl ...
Head-tail patterning of the vertebrate embryo: one, two or many
... the primordium of the notochord and other axial structures and with specific positional identity. It is crucial to bear this distinction only then acquire positional identities along the axis as a result of in mind when trying to understand the mechanisms responsible cell interactions. On the other ...
... the primordium of the notochord and other axial structures and with specific positional identity. It is crucial to bear this distinction only then acquire positional identities along the axis as a result of in mind when trying to understand the mechanisms responsible cell interactions. On the other ...
Functions of LIM proteins in cell polarity and chemotactic motility
... of two zinc atoms via the conserved cysteine, histidine and aspartate residues of the LIM consensus (Perez-Alvarado et al., 1994). Despite their ability to bind zinc ions and their structural similarity to zinc ®ngers, evidence available to date implicates LIM domains in protein±protein interactions ...
... of two zinc atoms via the conserved cysteine, histidine and aspartate residues of the LIM consensus (Perez-Alvarado et al., 1994). Despite their ability to bind zinc ions and their structural similarity to zinc ®ngers, evidence available to date implicates LIM domains in protein±protein interactions ...
PDF
... pallidum can be transformed with plasmid vectors, and genes of interest can be altered or knocked out by homologous recombination (Box 2). When required, multiple genes can be disrupted in potentially endless succession by excising the selectable marker after gene disruption with the Cre-loxP system ...
... pallidum can be transformed with plasmid vectors, and genes of interest can be altered or knocked out by homologous recombination (Box 2). When required, multiple genes can be disrupted in potentially endless succession by excising the selectable marker after gene disruption with the Cre-loxP system ...
chapter 9 telomeres and telomerase in adult stem cells and
... One of the best‑known cell‑intrinsic events associated with aging is the progressive shortening of telomeres, the natural ends of chromosomes. The speed at which telomeres shorten with aging seems to vary between men and women and can be influenced by factors considered to accelerate aging and to be ...
... One of the best‑known cell‑intrinsic events associated with aging is the progressive shortening of telomeres, the natural ends of chromosomes. The speed at which telomeres shorten with aging seems to vary between men and women and can be influenced by factors considered to accelerate aging and to be ...
A level Biology Summer Homework - North Bristol Post
... This work is set to help you make the transition from Year 11 to your Post-16 studies. It is very important that you complete it to a high standard as it will help you start to build to the skills you will need to do well at the North Bristol Post-16 Centre. 1. Complete the questions attached and br ...
... This work is set to help you make the transition from Year 11 to your Post-16 studies. It is very important that you complete it to a high standard as it will help you start to build to the skills you will need to do well at the North Bristol Post-16 Centre. 1. Complete the questions attached and br ...
(From the Section on Experimental Therapeutics, Laboratory of
... were of the same order of magnitude (Table II); and when the cells were grown on Cl*-labelled glutamic acid, both the glutamine and glutamic acid residues of the cell protein were found to have the same specific activity (13). Studies with other cells in primary culture will be necessary to determin ...
... were of the same order of magnitude (Table II); and when the cells were grown on Cl*-labelled glutamic acid, both the glutamine and glutamic acid residues of the cell protein were found to have the same specific activity (13). Studies with other cells in primary culture will be necessary to determin ...
Chapter 22: The Living Cell - Follow “Ironmtn.wordpress.com”
... 58. At the cellular and molecular level, in what key ways are plants and animals the same? In what essential ways are they different? How do these differences give the organism an advantage in its life strategies? Ans: Cellular respiration is the same; plants have chloroplasts, which allows them to ...
... 58. At the cellular and molecular level, in what key ways are plants and animals the same? In what essential ways are they different? How do these differences give the organism an advantage in its life strategies? Ans: Cellular respiration is the same; plants have chloroplasts, which allows them to ...
Differentially Expressed Fibroblast Growth Factors Regulate Skeletal
... and FGF-9) that lack a classical secretory signal sequence, FGF-1 and FGF-2 are implicated in regulating skeletal muscle development. Although both have been proposed to be released from cells only under conditions of cell lysis and cell death (McNiel et al., 1989; D'Amore, 1990; Muthukrishnan et al ...
... and FGF-9) that lack a classical secretory signal sequence, FGF-1 and FGF-2 are implicated in regulating skeletal muscle development. Although both have been proposed to be released from cells only under conditions of cell lysis and cell death (McNiel et al., 1989; D'Amore, 1990; Muthukrishnan et al ...
Alteration of the Cytoplasmic Domain of the Membrane
... mann, 1982, 1983; Roth et al., 1983; Stephens et al., 1986; Zuniga et al., 1983; Zuniga and Hood, 1986). The expression of wild-type influenza hemagglutinin and VSV G-protein in MDCK cells has shown that the information necessary for polar transport to the cell surface is contained within the amino ...
... mann, 1982, 1983; Roth et al., 1983; Stephens et al., 1986; Zuniga et al., 1983; Zuniga and Hood, 1986). The expression of wild-type influenza hemagglutinin and VSV G-protein in MDCK cells has shown that the information necessary for polar transport to the cell surface is contained within the amino ...
Regulatory role of rpL3 in cell response to nucleolar stress induced
... findings revealed novel stress response pathways, which function independently of p53 and still lead to cell cycle arrest and/or apoptosis. Given that most cancers lack functional p53, it is of great importance to study these emerging molecular mechanisms. p53-independent pathways that require nucleo ...
... findings revealed novel stress response pathways, which function independently of p53 and still lead to cell cycle arrest and/or apoptosis. Given that most cancers lack functional p53, it is of great importance to study these emerging molecular mechanisms. p53-independent pathways that require nucleo ...
Checkpoint Responses in Cancer Therapy
... The cell cycle is tightly regulated by a number of molecular entities that maintain the genetic integrity of the cell and ensure that genetic information is passed correctly to the daughter cells. Starting in the 1980s, extensive research efforts have revealed the existence of evolutionarily conserv ...
... The cell cycle is tightly regulated by a number of molecular entities that maintain the genetic integrity of the cell and ensure that genetic information is passed correctly to the daughter cells. Starting in the 1980s, extensive research efforts have revealed the existence of evolutionarily conserv ...
Through the Cell Membrane
... repel each other, a positively charged channel protein repels positively charged ions and a negatively charged channel protein repels negatively charged ions. BIO ...
... repel each other, a positively charged channel protein repels positively charged ions and a negatively charged channel protein repels negatively charged ions. BIO ...
Supporting Online Material for
... 2) or Fbxl3 (lanes 3 and 4, each expressing a different shRNA to human Fbxl3). Lane 1 shows a cell extract from un-infected cells (UI). Twenty-four hours postinfection, cells were trypsinized, replated, and cultured for three additional days. Finally, cells were collected, and protein extracts were ...
... 2) or Fbxl3 (lanes 3 and 4, each expressing a different shRNA to human Fbxl3). Lane 1 shows a cell extract from un-infected cells (UI). Twenty-four hours postinfection, cells were trypsinized, replated, and cultured for three additional days. Finally, cells were collected, and protein extracts were ...
T. brucei basal body component - Journal of Cell Science
... During cell division this structure directs the assembly of the new axoneme and is involved in mitochondrial DNA (kinetoplast) segregation (Robinson and Gull, 1991). In addition, it is believed to play a role in the organisation of four particular microtubules from the corset which unlike other micr ...
... During cell division this structure directs the assembly of the new axoneme and is involved in mitochondrial DNA (kinetoplast) segregation (Robinson and Gull, 1991). In addition, it is believed to play a role in the organisation of four particular microtubules from the corset which unlike other micr ...
MS Word preprint
... culture medium. This was followed by three washings, 5 minute each, in dye free medium, all at 37ºC. Subsequently, the cells were fixed for 20 min with 4% paraformaldehyde at room temperature. Cell permeabilization with ethanol reduced the cytoplasmic background. The cells were dehydrated and then r ...
... culture medium. This was followed by three washings, 5 minute each, in dye free medium, all at 37ºC. Subsequently, the cells were fixed for 20 min with 4% paraformaldehyde at room temperature. Cell permeabilization with ethanol reduced the cytoplasmic background. The cells were dehydrated and then r ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.