Activating the DNA damage checkpoint in a developmental context
... syncytial cycles delays not the entry into mitosis but the segregation of sister chromosomes during mitosis [7]. The mechanistic basis for this response remains to be understood. Syncytial cycles are followed by cellularization and maternal-to-zygotic transition of cell cycle control (MZT; similar t ...
... syncytial cycles delays not the entry into mitosis but the segregation of sister chromosomes during mitosis [7]. The mechanistic basis for this response remains to be understood. Syncytial cycles are followed by cellularization and maternal-to-zygotic transition of cell cycle control (MZT; similar t ...
Decreased Lysosomal Dipeptidyl Aminopeptidase I Fibroblasts
... A B S T R A C T Several lysosomal enzymes were assayed in cultured human skin fibroblasts from patients with Duchenne's muscular dystrophy (DMD) and age- and sex-matched control patients (N). The activity of four glycosidases, cathepsin B, and total autoproteolysis at pH 4.0 were unchanged between t ...
... A B S T R A C T Several lysosomal enzymes were assayed in cultured human skin fibroblasts from patients with Duchenne's muscular dystrophy (DMD) and age- and sex-matched control patients (N). The activity of four glycosidases, cathepsin B, and total autoproteolysis at pH 4.0 were unchanged between t ...
Bone marrow contribution to skeletal muscle: A physiological
... However, whether the participation of these cells is part of the normal response to injury remains a matter of debate. Using parabiotically joined pairs of genetically labeled and wildtype mice, we show here that irradiation-induced damage of the target tissue, injection of bone marrow into the circ ...
... However, whether the participation of these cells is part of the normal response to injury remains a matter of debate. Using parabiotically joined pairs of genetically labeled and wildtype mice, we show here that irradiation-induced damage of the target tissue, injection of bone marrow into the circ ...
Leaf epidermal studies of three species of Acalypha Linn.
... al., 2000). The leaf poultice is deam good for headache, swellings and cold in trinidad. Its leaf extract is active against Gram +ve bacteria, the extracts of seed have Immunomodulating properties that work against some tumors (Bussing et al. 1999). Cooked leaves of some other species of Acalypha ar ...
... al., 2000). The leaf poultice is deam good for headache, swellings and cold in trinidad. Its leaf extract is active against Gram +ve bacteria, the extracts of seed have Immunomodulating properties that work against some tumors (Bussing et al. 1999). Cooked leaves of some other species of Acalypha ar ...
as Adobe PDF - Edinburgh Research Explorer
... MSC lines have already been isolated from human placenta and amnionic and chorionic fetal membranes (reviewed in 36). At the developmental stages tested, ranging from week 3 to term, human MSC lines express classical mesenchymal markers as well as markers of pericytes, CD146 and NG2 22, 37, and afte ...
... MSC lines have already been isolated from human placenta and amnionic and chorionic fetal membranes (reviewed in 36). At the developmental stages tested, ranging from week 3 to term, human MSC lines express classical mesenchymal markers as well as markers of pericytes, CD146 and NG2 22, 37, and afte ...
Submembraneous microtubule cytoskeleton: biochemical and
... which becomes especially apparent under microtubules depolymerising conditions such as presence of nocodazol or increased Ca2+ concentrations [28]. TRPV1 channels are nonselective cation channels. Therefore, the role of increased concentration of Ca2+ on the properties of TRPV1–tubulin and ⁄ or TRPV ...
... which becomes especially apparent under microtubules depolymerising conditions such as presence of nocodazol or increased Ca2+ concentrations [28]. TRPV1 channels are nonselective cation channels. Therefore, the role of increased concentration of Ca2+ on the properties of TRPV1–tubulin and ⁄ or TRPV ...
SPECIAL HISTOLOGY Part 1
... centers for control and regulation of all nervous system function have become centralized in a process called encephalization. In lower animals the spinal cord has a great degree in independence from the brain, while in the human spinal cord function is directly under the regulation of the brain. Th ...
... centers for control and regulation of all nervous system function have become centralized in a process called encephalization. In lower animals the spinal cord has a great degree in independence from the brain, while in the human spinal cord function is directly under the regulation of the brain. Th ...
05 October 2000
... accumulation of S-RNases in pollen tubes germinated in vitro in solutions of purified SRNases has been previously reported14. However, in these studies, both pollen-tube RNA degradation14 and growth arrest15 were genotype-independent, and thus the genotype-independent S-RNase uptake was attributed t ...
... accumulation of S-RNases in pollen tubes germinated in vitro in solutions of purified SRNases has been previously reported14. However, in these studies, both pollen-tube RNA degradation14 and growth arrest15 were genotype-independent, and thus the genotype-independent S-RNase uptake was attributed t ...
as a PDF
... microtubules in Arabidopsis plants revealed that new microtubules initiated at the cell cortex and exhibited dynamics at both ends. Polymerization-biased dynamic instability at one end and slow depolymerization at the other resulted in sustained microtubule migration across the cell cortex by a hybr ...
... microtubules in Arabidopsis plants revealed that new microtubules initiated at the cell cortex and exhibited dynamics at both ends. Polymerization-biased dynamic instability at one end and slow depolymerization at the other resulted in sustained microtubule migration across the cell cortex by a hybr ...
- Wiley Online Library
... or amoeboid-based movement mediated by extension of plasma membrane protrusions—or blebs—into the extracellular matrix driven by local hydrodynamic changes in cytosolic pressure [17, 18]. We demonstrated that satellite cells move on their in vivo substrate using an amoeboid or bleb-dependent mechani ...
... or amoeboid-based movement mediated by extension of plasma membrane protrusions—or blebs—into the extracellular matrix driven by local hydrodynamic changes in cytosolic pressure [17, 18]. We demonstrated that satellite cells move on their in vivo substrate using an amoeboid or bleb-dependent mechani ...
Directional Gravity Sensing in Gravitropism
... grass pulvini contain developed thylakoid membranes (47, 79). Chlorophyll autofluorescence is observed in amyloplasts in endodermal cells as well as in chloroplasts in the neighboring cortical cells in Arabidopsis inflorescence stems (48). The chloroplasts in cortical cells occasionally contain small ...
... grass pulvini contain developed thylakoid membranes (47, 79). Chlorophyll autofluorescence is observed in amyloplasts in endodermal cells as well as in chloroplasts in the neighboring cortical cells in Arabidopsis inflorescence stems (48). The chloroplasts in cortical cells occasionally contain small ...
General principles of cellular communication
... change in cellular behaviour. The fidelity, accuracy and appropriateness of these cellular communication processes are critically important for the cell and for the organism. It is well known that aberrant cellular communication leads to conditions such as cancer, diabetes, heart failure and neurolo ...
... change in cellular behaviour. The fidelity, accuracy and appropriateness of these cellular communication processes are critically important for the cell and for the organism. It is well known that aberrant cellular communication leads to conditions such as cancer, diabetes, heart failure and neurolo ...
The measurement of exocytosis in plant cells
... plasma membrane growth and for its differentiation during the life of the cell is incorporated from the secretory vesicle membrane during exocytosis. For each of these processes (polysaccharide, protein and phospholipid delivery) there may be alternative routes, but the available evidence suggests t ...
... plasma membrane growth and for its differentiation during the life of the cell is incorporated from the secretory vesicle membrane during exocytosis. For each of these processes (polysaccharide, protein and phospholipid delivery) there may be alternative routes, but the available evidence suggests t ...
Ultrastructural immunocytochemical localization of
... much denser deposit than that overlying the endoblast (Figs 12 and 13). It is unlikely that the variability of this region was due to impaired accessibility of the reagents, since equally inaccessible regions showed ample deposit. As the basal lamina enters the region of the primitive streak or Hens ...
... much denser deposit than that overlying the endoblast (Figs 12 and 13). It is unlikely that the variability of this region was due to impaired accessibility of the reagents, since equally inaccessible regions showed ample deposit. As the basal lamina enters the region of the primitive streak or Hens ...
System approaches to study root hairs as a single cell plant model
... proportion of non-responding cells. For example, if a gene is expressed at a low level, does this mean that it is indeed lowly expressed or is it highly expressed, but only in a few cells? In order to avoid these issues, we adopted the soybean root hair cell, derived from a single, differentiated ro ...
... proportion of non-responding cells. For example, if a gene is expressed at a low level, does this mean that it is indeed lowly expressed or is it highly expressed, but only in a few cells? In order to avoid these issues, we adopted the soybean root hair cell, derived from a single, differentiated ro ...
GSK-3 Promotes Cell Survival, Growth, and PAX3 Levels in Human
... phosphorylation and increased levels of PAX3. Mol Cancer Res; 10(8); 1065–76. 2012 AACR. ...
... phosphorylation and increased levels of PAX3. Mol Cancer Res; 10(8); 1065–76. 2012 AACR. ...
Tetramer Staining T Cells with Optimized HLA Class II + CD4
... CD4⫹ T cells in PBMC remained difficult, mainly because the cells are rare in peripheral blood (17–20). Virtually all studies reporting MHCII tetramer staining used high concentrations of tetramer (20 g/ml or more), long incubation times (1–5 h) and temperatures of 23 or 37°C (8 –10, 13–17, 21–27). ...
... CD4⫹ T cells in PBMC remained difficult, mainly because the cells are rare in peripheral blood (17–20). Virtually all studies reporting MHCII tetramer staining used high concentrations of tetramer (20 g/ml or more), long incubation times (1–5 h) and temperatures of 23 or 37°C (8 –10, 13–17, 21–27). ...
The impact of abiotic factors on cellulose synthesis
... Kang et al., 2008). Interestingly, this rsw2-1 mutant genetically interacted with both complex glycan1 (cgl1) and staurosporin and temperature sensitive 3a (stt3a) mutants, which are defective in the production of complex-type N-glycans and in the unfolded protein response, respectively. Both rsw2- ...
... Kang et al., 2008). Interestingly, this rsw2-1 mutant genetically interacted with both complex glycan1 (cgl1) and staurosporin and temperature sensitive 3a (stt3a) mutants, which are defective in the production of complex-type N-glycans and in the unfolded protein response, respectively. Both rsw2- ...
PDF
... 1991) or phytohemagglutinin (Höfte et al., 1991). Thus, a picture of the Golgi apparatus as the central processing/targeting compartment of the plant cell is slowly being constructed (Harris and Watson, 1991). However, there are still many questions to be answered as to the exact organisation of fun ...
... 1991) or phytohemagglutinin (Höfte et al., 1991). Thus, a picture of the Golgi apparatus as the central processing/targeting compartment of the plant cell is slowly being constructed (Harris and Watson, 1991). However, there are still many questions to be answered as to the exact organisation of fun ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).