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Profile Documents Logout
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PDF - Potter Lab
PDF - Potter Lab

... to be alleles of the gigas locus (Canal et al., 1994; Ito and Rubin, 1999). Strikingly, cells mutant for Tsc2 in the eye and wing increase cell size without affecting differentiation. It was suggested that the large cell phenotype may be caused by endoreplication (Ito and Rubin, 1999). Moreover, org ...
Characterization of the effects of antiepileptic drugs on bone
Characterization of the effects of antiepileptic drugs on bone

Full Text  - The International Journal of Developmental Biology
Full Text - The International Journal of Developmental Biology

Platelet granule exocytosis: a comparison with chromaffin cells
Platelet granule exocytosis: a comparison with chromaffin cells

... to distinct compartments and were differentially released by different agonists (Italiano et al., 2008). The molecular mechanisms that mediate differential release are unclear. Differential distribution of SNAREs among subpopulations of α-granules may account for differential release. For example, P ...
Tissues
Tissues

... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Cytostatic factor: an activity that puts the cell cycle on hold
Cytostatic factor: an activity that puts the cell cycle on hold

... fertilization, the egg quickly completes the second meiotic division to generate a haploid pronucleus that can then fuse with the male pronucleus to form a diploid zygote. In their classic study, more than three decades ago, Masui and Markert found that the cytoplasm of mature eggs contains two diff ...
The plant Golgi apparatus—Going with the flow
The plant Golgi apparatus—Going with the flow

... a family of sugar transporters needed for complex polysaccharide synthesis has been described and located to the GA [33]. Lipid modifications are also important, many tasks taking place at the Golgi level, leading to a plant specific plasma membrane composition [34 – 36]. Mature cargo molecules (mem ...
RCAI Annual Report 2006 (PDF 5.6M)
RCAI Annual Report 2006 (PDF 5.6M)

... research funding. RIKEN’s budget is set to shrink rather than increase. This annual reduction in base funding allocations is not particular to RIKEN or RCAI. Rather, it is motivated by the fact that most research organizations, including RIKEN, also fall under legislation which requests a minimum an ...
Did trypanosomatid parasites have photosynthetic
Did trypanosomatid parasites have photosynthetic

... whether or not the researcher is versed in the basic biology of the organisms, and when the breadth of phylogenetic questions increases, so does the level of difficulty that is associated with trying to integrate all of the available information known about diverse groups. Consequently, as the focus ...
Flow-through electroporation based on constant voltage
Flow-through electroporation based on constant voltage

... 3.1. Effects of the low field in the wide sections on transfection One important advantage of our flow-through electroporation technique is that the sequence of the electric field variations (equivalent to the pulse pattern in electropulsation) can be conveniently adjusted by altering the geometry of t ...
Antibody Binding to Cryptococcus neoformans Impairs Budding by
Antibody Binding to Cryptococcus neoformans Impairs Budding by

Influence of Bacillus subtilis Cell Walls and EDTA on Calcite
Influence of Bacillus subtilis Cell Walls and EDTA on Calcite

... laboratory and field studies have demonstrated that the presence of certain bacteria influences the rate of mineral dissolution (1-4), but the dissolution mechanisms in aqueous solutions remain poorly characterized, even in abiotic systems. Bacteria are a common component in weathering environments. ...
Characterization of Type I and IV Collagens by Raman
Characterization of Type I and IV Collagens by Raman

... License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract. Type I and IV collagens are important constituents of the skin. Type I collagen is found in all dermal layers in high proportion, while type IV collagen is l ...
Early development of the zebrafish pronephros and analysis of
Early development of the zebrafish pronephros and analysis of

... 4656 I. A. Drummond and others to kidneys in higher vertebrates, as evidenced by the cellular architecture of the pronephric glomerulus and in the specialized transport functions of pronephric tubular epithelial cells (Tytler, 1988). These features make the zebrafish pronephros a simple and accessi ...
Skeletal Muscle
Skeletal Muscle

... The two terminal cistemae of the SR together with their associated T tubule are known as a triad. Inside the muscle fibre, the T-tubules lie next to the terminal cisternae of an internal membrane system derived from the endoplasmic reticulum, called the sarcoplasmic reticulum (SR), which is a store ...
Direct detection of ligand–protein interaction using AFM
Direct detection of ligand–protein interaction using AFM

The viability assessment of Microcystis aeruginosa cells after co-culturing
The viability assessment of Microcystis aeruginosa cells after co-culturing

... such a method and has been used to assess viability of Microcystis spp. following exposure to different environmental stress factors such as nutrient limitation (Brookes et al., 2000), nutrient enrichment (Latour et al., 2004), copper toxicity (Franklin et al., 2004; Hadjoudja et al., 2009), turbule ...
Amyloplasts and Vacuolar Membrane Dynamics in
Amyloplasts and Vacuolar Membrane Dynamics in

The twin arginine protein transport pathway exports multiple
The twin arginine protein transport pathway exports multiple

... links.html). However, both of these programmes generate a degree of false positive and false negative predictions; for example, when applied to the genome sequence of E. coli, both programmes overpredict Tat substrates by 20–25% (Dilks et al., 2003; Bendtsen et al., 2005). In general, the sets of ca ...
Suppressor analysis of the protein kinase Elm1p, an enzyme
Suppressor analysis of the protein kinase Elm1p, an enzyme

... bud neck during the budded phase of the cell cycle. Overexpression of Sel2p results in a growth arrest late in mitosis that is suppressed by mutations in Clb2p, and an allele of CDC28, suggesting that Sel2p degradation may be required for the telophase to G1 cell cycle transition. ...
Kratsch, H.A . and R.R. Wise.  2000.  The ultrastructure of chilling stress.  Plant, Cell Environment 23: 337-350.
Kratsch, H.A . and R.R. Wise.  2000.  The ultrastructure of chilling stress.  Plant, Cell Environment 23: 337-350.

... are less susceptible to chilling injury. Organellar development and ontogeny may also be disrupted. The inherent chilling sensitivity of a plant, as well as the ability of some species to acclimate to chilling, influence the timing and appearance of ultrastructural injury with the resulting outcome ...
The ultrastructure of chilling stress
The ultrastructure of chilling stress

... are less susceptible to chilling injury. Organellar development and ontogeny may also be disrupted. The inherent chilling sensitivity of a plant, as well as the ability of some species to acclimate to chilling, influence the timing and appearance of ultrastructural injury with the resulting outcome ...
Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts,...
Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts,...

... Notch 2, as a binding partner of APP (Fassa et al. 2005; Fischer et al. 2005; Oh et al. 2005; Chen et al. 2006). Notch receptors are type I transmembrane proteins playing a critical role in both vertebrates and invertebrates during embryonic development and throughout the adult life. Notch proteins ...
Slow axonal transport and the genesis of neuronal morphology
Slow axonal transport and the genesis of neuronal morphology

... probably already identified motors such as cytoplasmic dynein and members of the myosin and kinesin families. In fact, it has already been demonstrated that such motors, when adhered to glass coverslips, can support the rapid movement of cytoskeletal polymers along the surface of the glass (for revi ...
Genetic modification of wood quality for second
Genetic modification of wood quality for second

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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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