Pepcid - Transplant Companions
... Famotidine exhibits a linear pharmacokinetic profile for AUC and gastric pH in the 5- to 40-mg range. In this same range, associations have been demonstrated between mean plasma famotidine concentrations and mean inhibition of meal-stimulated acid secretion. However “area under the gastric pH-time c ...
... Famotidine exhibits a linear pharmacokinetic profile for AUC and gastric pH in the 5- to 40-mg range. In this same range, associations have been demonstrated between mean plasma famotidine concentrations and mean inhibition of meal-stimulated acid secretion. However “area under the gastric pH-time c ...
Antidote–Opioids
... restricted because of its poor lipid solubility and inability to cross the blood–brain barrier.79 After SC administration, peak serum concentrations occur in about 30 minutes. The drug has a Vd of 1.1 L/kg and is minimally protein bound (11%–15%). Although there are several metabolites, 85% of the d ...
... restricted because of its poor lipid solubility and inability to cross the blood–brain barrier.79 After SC administration, peak serum concentrations occur in about 30 minutes. The drug has a Vd of 1.1 L/kg and is minimally protein bound (11%–15%). Although there are several metabolites, 85% of the d ...
Amitriptyline Hydrochloride 10mg/5ml Oral Solution PL 29831/0460
... conditions of use. It is not intended to provide practical advice on how to use Amitriptyline Hydrochloride 10mg/5ml Oral Solution. For practical information about using Amitriptyline Hydrochloride 10mg/5ml Oral Solution, patients should read the package leaflet or contact their doctor or pharmacist ...
... conditions of use. It is not intended to provide practical advice on how to use Amitriptyline Hydrochloride 10mg/5ml Oral Solution. For practical information about using Amitriptyline Hydrochloride 10mg/5ml Oral Solution, patients should read the package leaflet or contact their doctor or pharmacist ...
Cardizem LA
... keratosis and hyperpigmentation at sun-exposed skin areas), purpura, retinopathy, myopathy, and thrombocytopenia. In addition, events such as myocardial infarction have been observed which are not readily distinguishable from the natural history of the disease in these patients. A number of well-doc ...
... keratosis and hyperpigmentation at sun-exposed skin areas), purpura, retinopathy, myopathy, and thrombocytopenia. In addition, events such as myocardial infarction have been observed which are not readily distinguishable from the natural history of the disease in these patients. A number of well-doc ...
ramelteon
... minutes prior to the start of the dark period to characterize their effects on sleep and wakefulness (light NREM [Non-rapid eye movement] sleep [Stage 1 and Stage 2, Light Sleep: LS], slow wave sleep [Stage 3 and Stage 4, Slow Wave Sleep: SWS], REM [Rapid eye movement] sleep). Ramelteon (0.3 mg/kg) ...
... minutes prior to the start of the dark period to characterize their effects on sleep and wakefulness (light NREM [Non-rapid eye movement] sleep [Stage 1 and Stage 2, Light Sleep: LS], slow wave sleep [Stage 3 and Stage 4, Slow Wave Sleep: SWS], REM [Rapid eye movement] sleep). Ramelteon (0.3 mg/kg) ...
VetyFormula2009
... pints etc). SI stands for Systeme Internationale and it is now recognized as the standard system for measurement in most disciplines around the world. The SI system defines a base unit for a particular measurement (for example the gram for measuring weight) and a prefix (e.g. kilo, milli) when the a ...
... pints etc). SI stands for Systeme Internationale and it is now recognized as the standard system for measurement in most disciplines around the world. The SI system defines a base unit for a particular measurement (for example the gram for measuring weight) and a prefix (e.g. kilo, milli) when the a ...
Warfarin Management - Adult - Ambulatory Clinical Practice Guideline
... 5. Initial dosing should be tailored based on patient bleed risk, potential sensitivity to warfarin, indication for anticoagulation, goal INR range and if potential drug interactions are present3 (Class I, Level C) 6. A baseline INR should be resulted prior to initiating warfarin therapy3 (Class I, ...
... 5. Initial dosing should be tailored based on patient bleed risk, potential sensitivity to warfarin, indication for anticoagulation, goal INR range and if potential drug interactions are present3 (Class I, Level C) 6. A baseline INR should be resulted prior to initiating warfarin therapy3 (Class I, ...
Pharmacology of anabolic steroids
... Athletes and bodybuilders have recognized for several decades that the use of anabolic steroids can promote muscle growth and strength but it is only relatively recently that these agents are being revisited for clinical purposes. Anabolic steroids are being considered for the treatment of cachexia ...
... Athletes and bodybuilders have recognized for several decades that the use of anabolic steroids can promote muscle growth and strength but it is only relatively recently that these agents are being revisited for clinical purposes. Anabolic steroids are being considered for the treatment of cachexia ...
TARKA - RxAbbVie
... The terminal half-life of verapamil is 6-11 hours. Steady-state plasma concentrations of the two components are achieved after about a week of once-daily dosing of TARKA. At steady-state, plasma concentrations of verapamil and trandolaprilat are up to two-fold higher than those observed after a sin ...
... The terminal half-life of verapamil is 6-11 hours. Steady-state plasma concentrations of the two components are achieved after about a week of once-daily dosing of TARKA. At steady-state, plasma concentrations of verapamil and trandolaprilat are up to two-fold higher than those observed after a sin ...
data sheet
... phenobarbital showed synergistic anticonvulsant activity, while combination with phenytoin showed additive anticonvulsant activity. In well controlled add-on trials, no correlation has been demonstrated between trough plasma concentrations of topiramate and its clinical efficacy. No evidence of tole ...
... phenobarbital showed synergistic anticonvulsant activity, while combination with phenytoin showed additive anticonvulsant activity. In well controlled add-on trials, no correlation has been demonstrated between trough plasma concentrations of topiramate and its clinical efficacy. No evidence of tole ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Table – 7 shows comparison of time taken and total antihypertensive doses required to control BP between two groups, i.e. to achieve BP 150/90mm of Hg. The mean time required were 47.2 ± 13.5 mins in the Labetalol groups and 45.6 ± 14.5 minutes in the Nifedipine group. This comparison showed no diff ...
... Table – 7 shows comparison of time taken and total antihypertensive doses required to control BP between two groups, i.e. to achieve BP 150/90mm of Hg. The mean time required were 47.2 ± 13.5 mins in the Labetalol groups and 45.6 ± 14.5 minutes in the Nifedipine group. This comparison showed no diff ...
icrs2015 programme - The International Cannabinoid Research
... Symposium Programming by Cortical Systematics LLC ...
... Symposium Programming by Cortical Systematics LLC ...
Buprenorphine Bluefish sublingual tablet ENG SmPC
... As buprenorphine is an opioid, pain as a symptom of a disease, may be inhibited. Buprenorphine may cause drowsiness, which may be exacerbated by concurrent use of other centrally acting substances, such as alcohol, sedatives and hypnotics (see section 4.5). Orthostatic hypotension may occur. Studies ...
... As buprenorphine is an opioid, pain as a symptom of a disease, may be inhibited. Buprenorphine may cause drowsiness, which may be exacerbated by concurrent use of other centrally acting substances, such as alcohol, sedatives and hypnotics (see section 4.5). Orthostatic hypotension may occur. Studies ...
- Wiley Online Library
... actorrhoea or symptoms of thyroid dysfunction should be investigated because hyperprolactinaemia can be accompanied by increased adrenal androgens (7,15). Acromegaly is suggested by the coarsening of facial features or by hand enlargement (4). Acne, seborrhoea, temporal balding and acanthosis nigric ...
... actorrhoea or symptoms of thyroid dysfunction should be investigated because hyperprolactinaemia can be accompanied by increased adrenal androgens (7,15). Acromegaly is suggested by the coarsening of facial features or by hand enlargement (4). Acne, seborrhoea, temporal balding and acanthosis nigric ...
product information - cardizem® cd
... therapy with diltiazem produces no change or an increase in plasma catecholamines. No increased activity of the renin-angiotensin-aldosterone axis has been observed. Diltiazem reverses the renal and peripheral effects of angiotensin II. Hypertensive animal models respond to diltiazem with reductions ...
... therapy with diltiazem produces no change or an increase in plasma catecholamines. No increased activity of the renin-angiotensin-aldosterone axis has been observed. Diltiazem reverses the renal and peripheral effects of angiotensin II. Hypertensive animal models respond to diltiazem with reductions ...
evaluation of antidepressant like activity of curcumin and its
... FST in glass jar was performed as described by Porsolt et al. with few modifications (13). This test consists of two parts, an initial training period of 15 min followed by actual test for 5 min duration 24 h later. Mice were individually forced to swim inside a vertical borosilicate glass cylinder ...
... FST in glass jar was performed as described by Porsolt et al. with few modifications (13). This test consists of two parts, an initial training period of 15 min followed by actual test for 5 min duration 24 h later. Mice were individually forced to swim inside a vertical borosilicate glass cylinder ...
Triumeq - ViiV Healthcare
... patients aware that a hypersensitivity reaction can occur with reintroduction of TRIUMEQ or any other abacavir-containing product and that reintroduction of TRIUMEQ or introduction of any other abacavir-containing product needs to be undertaken only if medical care can be readily accessed by the pat ...
... patients aware that a hypersensitivity reaction can occur with reintroduction of TRIUMEQ or any other abacavir-containing product and that reintroduction of TRIUMEQ or introduction of any other abacavir-containing product needs to be undertaken only if medical care can be readily accessed by the pat ...
Frequently asked questions about CELEBREX
... ---------------------------WARNINGS AND PRECAUTIONS--------------------------• Serious and potentially fatal cardiovascular (CV) thrombotic events, myocardial infarction, and stroke. Patients with known CV disease/risk factors may be at greater risk (5.1, 14.6, 17.2). • Serious gastrointestinal (GI) ...
... ---------------------------WARNINGS AND PRECAUTIONS--------------------------• Serious and potentially fatal cardiovascular (CV) thrombotic events, myocardial infarction, and stroke. Patients with known CV disease/risk factors may be at greater risk (5.1, 14.6, 17.2). • Serious gastrointestinal (GI) ...
You May Pay Less for Brand-Name CELEBREX Than the Generic
... you have heart disease or risk factors for it, such as high blood pressure or when NSAIDs are taken for long periods. CELEBREX should not be used right before or after certain heart surgeries. Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers, can occur without wa ...
... you have heart disease or risk factors for it, such as high blood pressure or when NSAIDs are taken for long periods. CELEBREX should not be used right before or after certain heart surgeries. Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers, can occur without wa ...
TOPAMAX® - Janssen
... The tablet and capsule formulations of TOPAMAX are bioequivalent at equivalent doses. The pharmacokinetic profile of topiramate compared to other antiepileptic drugs shows a long plasma elimination half-life, linear pharmacokinetics, predominantly renal clearance, absence of significant protein bind ...
... The tablet and capsule formulations of TOPAMAX are bioequivalent at equivalent doses. The pharmacokinetic profile of topiramate compared to other antiepileptic drugs shows a long plasma elimination half-life, linear pharmacokinetics, predominantly renal clearance, absence of significant protein bind ...
AusPAR: Lisdexamfetamine dimesilate
... Lisdexamfetamine is a centrally acting sympathomimetic. It is a prodrug of dexamphetamine1 which is a central nervous system (CNS) stimulant. The lisdexamfetamine parent compound does not bind to the sites responsible for the reuptake of noradrenaline and dopamine in vitro and is not thought to cont ...
... Lisdexamfetamine is a centrally acting sympathomimetic. It is a prodrug of dexamphetamine1 which is a central nervous system (CNS) stimulant. The lisdexamfetamine parent compound does not bind to the sites responsible for the reuptake of noradrenaline and dopamine in vitro and is not thought to cont ...
AusPAR: Lisdexamfetamine dimesilate
... The drug products are Size 3 hard gelatine capsules, each containing LDX 30 mg, 50 mg or 70 mg (equivalent to 8.9 mg, 14.8 mg and 20.8 mg of dexamphetamine base, respectively). The philosophy in the choice of an immediate release capsule dosage form over other alternatives was not discussed. However ...
... The drug products are Size 3 hard gelatine capsules, each containing LDX 30 mg, 50 mg or 70 mg (equivalent to 8.9 mg, 14.8 mg and 20.8 mg of dexamphetamine base, respectively). The philosophy in the choice of an immediate release capsule dosage form over other alternatives was not discussed. However ...
Guidelines for warfarin management in the community
... greater than 2. Whilst the CHADS2 score is simple it does not include many common stroke risk factors. The CHA2DS2VASc score (see Table 3) is inclusive of the most common stroke risk factors in everyday clinical practice and has been validated in multiple cohorts; the accumulated evidence shows that ...
... greater than 2. Whilst the CHADS2 score is simple it does not include many common stroke risk factors. The CHA2DS2VASc score (see Table 3) is inclusive of the most common stroke risk factors in everyday clinical practice and has been validated in multiple cohorts; the accumulated evidence shows that ...
Antinociceptive effect of Ferula assa-foetida oleo-gum
... stimulus at 15 min time point in animals receiving 25 and 50 mg/kg asafoetida were statically similar to those who administrated by morphine sulfate (P>0.05). Acetic acid-induced writhing test The effect of different treatments on acetic acid induced writhing is presented in Table 2. The percentage ...
... stimulus at 15 min time point in animals receiving 25 and 50 mg/kg asafoetida were statically similar to those who administrated by morphine sulfate (P>0.05). Acetic acid-induced writhing test The effect of different treatments on acetic acid induced writhing is presented in Table 2. The percentage ...
essential veterinary drugs
... ii Table of contents PART-I-Estimation of body weight in Livestock ...................................................................................................... 1 PART-II ....................................................................................................................... ...
... ii Table of contents PART-I-Estimation of body weight in Livestock ...................................................................................................... 1 PART-II ....................................................................................................................... ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.