Breast Chemotherapy Regimen v 3.5 Oct 2015
... after the start of subsequent doses. If the patient tolerates the previous cycles then cycles 2 and 3 may be monitored for 30 minutes post infusion and cycle 4 onwards does not require monitoring however this is unlicensed and the patient needs to be informed and consented Cycle Frequency: Loading d ...
... after the start of subsequent doses. If the patient tolerates the previous cycles then cycles 2 and 3 may be monitored for 30 minutes post infusion and cycle 4 onwards does not require monitoring however this is unlicensed and the patient needs to be informed and consented Cycle Frequency: Loading d ...
new zealand data sheet
... acute pain, and in those with mental depression. They should be given cautiously to patients with impaired hepatic, renal, or respiratory function and may be contraindicated when the impairment is severe. They are also contra-indicated in patients with acute porphyrias. Care is required when withdra ...
... acute pain, and in those with mental depression. They should be given cautiously to patients with impaired hepatic, renal, or respiratory function and may be contraindicated when the impairment is severe. They are also contra-indicated in patients with acute porphyrias. Care is required when withdra ...
butorphanol tartrate injection usp
... In human studies involving individuals without significant respiratory dysfunction, 2 mg of butorphanol IV and 10 mg of morphine sulfate IV depressed respiration to a comparable degree. At higher doses, the magnitude of respiratory depression with butorphanol is not appreciably increased; however, t ...
... In human studies involving individuals without significant respiratory dysfunction, 2 mg of butorphanol IV and 10 mg of morphine sulfate IV depressed respiration to a comparable degree. At higher doses, the magnitude of respiratory depression with butorphanol is not appreciably increased; however, t ...
How can one be sure to get a good quality Pregnenolone product
... What Does Pregnenolone Do? Clinical research has shown Pregnenolone to be important for nerve and brain health, having also been found to be a potent memory and learning skill enhancer – maybe the most important so far discovered. It is also known to relieve arthritis. Pregnenolone has been used in ...
... What Does Pregnenolone Do? Clinical research has shown Pregnenolone to be important for nerve and brain health, having also been found to be a potent memory and learning skill enhancer – maybe the most important so far discovered. It is also known to relieve arthritis. Pregnenolone has been used in ...
New Zealand Datasheet Name of Medicine Presentation CIPROFLOXACIN
... ciprofloxacin beginning 24 hours post-exposure was significantly lower (1/9), compared to the placebo group (9/10) [p = 0.001]. The one ciprofloxacin-treated animal that died of anthrax did so following the 30-day drug administration period. ...
... ciprofloxacin beginning 24 hours post-exposure was significantly lower (1/9), compared to the placebo group (9/10) [p = 0.001]. The one ciprofloxacin-treated animal that died of anthrax did so following the 30-day drug administration period. ...
Ketorolac Tromethamine Injection, USP
... Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. The mechanism of action of ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. The biological activity ...
... Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. The mechanism of action of ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. The biological activity ...
![[FDA Approved Labeling for Zoloft® for the Treatment of Social... Attachment to FDA Approval Letter for NDA 19-839/S-045]](http://s1.studyres.com/store/data/007848075_2-b414df0c18881254f6b13983cc9df393-300x300.png)
[FDA Approved Labeling for Zoloft® for the Treatment of Social... Attachment to FDA Approval Letter for NDA 19-839/S-045]
... been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of sertraline was found in animals to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the tre ...
... been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of sertraline was found in animals to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the tre ...
Ketorolac Tromethamine
... Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. The mechanism of action of ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. The biological activity ...
... Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. The mechanism of action of ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. The biological activity ...
PRODUCT MONOGRAPH OFLOXACIN TABLETS 200, 300 and 400 mg
... were similar to those found in plasma. Because of the potential for serious adverse reactions from ofloxacin in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. (See WARNINGS and ADVERS ...
... were similar to those found in plasma. Because of the potential for serious adverse reactions from ofloxacin in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. (See WARNINGS and ADVERS ...
product information
... receiving anti-epileptic drugs and patients with chronic pain. Absorption Pregabalin is rapidly absorbed when administered in the fasted state, with peak plasma concentrations occurring within 1 hour following both single and multiple dose administration. Pregabalin oral bioavailability is estimated ...
... receiving anti-epileptic drugs and patients with chronic pain. Absorption Pregabalin is rapidly absorbed when administered in the fasted state, with peak plasma concentrations occurring within 1 hour following both single and multiple dose administration. Pregabalin oral bioavailability is estimated ...
zenhale
... to ZENHALE®, because deaths due to adrenal insufficiency have occurred in asthmatic patients during and after transfer from systemic corticosteroids to less systemically available inhaled corticosteroids. After withdrawal from systemic corticosteroids, a number of months are required for recovery of ...
... to ZENHALE®, because deaths due to adrenal insufficiency have occurred in asthmatic patients during and after transfer from systemic corticosteroids to less systemically available inhaled corticosteroids. After withdrawal from systemic corticosteroids, a number of months are required for recovery of ...
Ciprofloxacin Mylan 500 mg film
... Ciprofloxacin should generally not be used in patients with a history of tendon disease/disorder related to quinolone treatment. Nevertheless, in very rare instances, after microbiological documentation of the causative organism and evaluation of the risk/benefit balance, ciprofloxacin may be prescr ...
... Ciprofloxacin should generally not be used in patients with a history of tendon disease/disorder related to quinolone treatment. Nevertheless, in very rare instances, after microbiological documentation of the causative organism and evaluation of the risk/benefit balance, ciprofloxacin may be prescr ...
RISPERDAL CONSTA
... Co-administration of carbamazepine and other CYP 3A4 enzyme inducers (e.g., phenytoin, rifampin, phenobarbital) with risperidone would be expected to cause decreases in the plasma concentrations of the sum of risperidone and 9-hydroxyrisperidone combined, which could lead to decreased efficacy of RI ...
... Co-administration of carbamazepine and other CYP 3A4 enzyme inducers (e.g., phenytoin, rifampin, phenobarbital) with risperidone would be expected to cause decreases in the plasma concentrations of the sum of risperidone and 9-hydroxyrisperidone combined, which could lead to decreased efficacy of RI ...
Valproate Learning Objectives Outline Indications
... • Because the protein binding is saturable, the relationship between dose and total VPA concentration is nonlinear: concentration does not ↑ proportionally with the dose, but rather ↑ to a lesser extent • However, the kinetics of unbound VPA are linear ...
... • Because the protein binding is saturable, the relationship between dose and total VPA concentration is nonlinear: concentration does not ↑ proportionally with the dose, but rather ↑ to a lesser extent • However, the kinetics of unbound VPA are linear ...
If this leaflet is difficult to see or read please contact the following
... Consideration should be given to official guidance on the appropriate use of antibacterial agents. 4.2 Posology and method of administration For intravenous infusion and oral use only and not for intramuscular administration. Infusion-related adverse events are related to both concentration and rate ...
... Consideration should be given to official guidance on the appropriate use of antibacterial agents. 4.2 Posology and method of administration For intravenous infusion and oral use only and not for intramuscular administration. Infusion-related adverse events are related to both concentration and rate ...
ranitidine oral
... period in any patient. Median peak and trough plasma bismuth concentrations were 105 and 68% of predicted steady-state peak and trough concentrations, respectively, on day 28.11 In a study in which ranitidine bismuth citrate 400 mg twice daily was administered for 12 weeks (3 times the recommended d ...
... period in any patient. Median peak and trough plasma bismuth concentrations were 105 and 68% of predicted steady-state peak and trough concentrations, respectively, on day 28.11 In a study in which ranitidine bismuth citrate 400 mg twice daily was administered for 12 weeks (3 times the recommended d ...
WARNINGS - Boehringer Ingelheim
... approximately 5% of the albumin binding sites. Thus, the unbound fraction for each enantiomer will be constant over the therapeutic range. A decrease in serum albumin, however, will result in increased free drug concentrations. Ketorolac tromethamine is excreted in human milk (see PRECAUTIONS: Nursi ...
... approximately 5% of the albumin binding sites. Thus, the unbound fraction for each enantiomer will be constant over the therapeutic range. A decrease in serum albumin, however, will result in increased free drug concentrations. Ketorolac tromethamine is excreted in human milk (see PRECAUTIONS: Nursi ...
1. Clinical Pharmacology
... Side effects of buprenorphine are similar to other opioids Under certain circumstances, buprenorphine may precipitate opioid withdrawal symptoms one to four hours after the first dose. It has a higher affinity and lower intrinsic activity than full agonists such as methadone, morphine or heroin. Con ...
... Side effects of buprenorphine are similar to other opioids Under certain circumstances, buprenorphine may precipitate opioid withdrawal symptoms one to four hours after the first dose. It has a higher affinity and lower intrinsic activity than full agonists such as methadone, morphine or heroin. Con ...
... gm.day-1, there were a mean increase in FEV1 of 13.4%, a decrease in b-agonist usage by 24%, an improvement in morning peak expiratory flow rate of 10%, a decrease in overall symptom scores of 37%, and a decrease in urinary leukotriene excretion by 39% [72]. There were no significant side-effects re ...
- Boehringer Ingelheim (Canada)
... In rats, co-administration of a Vitamin E derivative increased the bleeding effects of tipranavir (see Toxicology section). However, analyses of stored plasma from adults treated with APTIVUS capsules plus low-dose ritonavir, and from paediatric patients treated with APTIVUS capsules or tipranavir ...
... In rats, co-administration of a Vitamin E derivative increased the bleeding effects of tipranavir (see Toxicology section). However, analyses of stored plasma from adults treated with APTIVUS capsules plus low-dose ritonavir, and from paediatric patients treated with APTIVUS capsules or tipranavir ...
ASAM: Safe Methadone Induction and Stabilization
... Despite its proven efficacy, methadone’s relatively short duration of analgesic effect, coupled with its long elimination half-life and potential for interactions with multiple drugs, increases the risk of toxicity and adverse events (FDA, 2007). As a result, methadone-related visits to emergency de ...
... Despite its proven efficacy, methadone’s relatively short duration of analgesic effect, coupled with its long elimination half-life and potential for interactions with multiple drugs, increases the risk of toxicity and adverse events (FDA, 2007). As a result, methadone-related visits to emergency de ...
Methylphenidate Hydrochloride Oral Solution
... Know the medicines that you or your child takes. Keep a list of your medicines with you to show your doctor and pharmacist. Do not start any new medicine while taking methylphenidate hydrochloride oral solution without talking to your doctor first. How should methylphenidate hydrochloride oral solut ...
... Know the medicines that you or your child takes. Keep a list of your medicines with you to show your doctor and pharmacist. Do not start any new medicine while taking methylphenidate hydrochloride oral solution without talking to your doctor first. How should methylphenidate hydrochloride oral solut ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.