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Daily Telegraph - Medicines for Malaria Venture
Daily Telegraph - Medicines for Malaria Venture

... In the sad task of getting to grips with a global Aids epidemic, the world’s second most deadly disease has been overshadowed. The World Health Organisation (WHO) estimates that 38 million people worldwide were living with HIV in 2003; almost three million were killed by Aids the same year. Malaria, ...
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... 4/8/2009 1:23:26 PM ...
ANALYSIS  OF COMPARTMENT  MODELS, KINETICS  OF
ANALYSIS OF COMPARTMENT MODELS, KINETICS OF

... 1st order elimination, excretion & absorption rate constants & fractions excreted unchanged can be computed from such data. 1st order metabolism or extra renal excretion rate constant can also be calculated subsequently from the difference [KE-Ke] = Km Direct measurement of bioavailability can also ...
Stable drug encapsulation in micelles and microemulsions
Stable drug encapsulation in micelles and microemulsions

... dissolution step. Micellar and microemulsion systems, being the most dispersed of all, appear the most promising. While these systems show high drug entrapment and release under sink conditions, the improvement in oral drug bioavailability is often unpredictable. The formulation and drug-related bio ...
Pharmaceuticals: Focussing on Appropriate Utilization
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... This Repository is unique in terms of its comprehensiveness, degree of integration, and orientation around an anonymized population registry. Members of MCHP consult extensively with government officials, health care administrators, and clinicians to develop a research agenda that is topical and rel ...
Full Article - Pharmascope.org
Full Article - Pharmascope.org

... of the skin. As indicative by the wide range in this reported value, there are considerable differences in permeability between different regions of the oral cavity because of the diverse structures and functions of the different oral mucosa. In general, the permeabilities of the oral mucosae decrea ...
Bossong et al 2005 proefprint AB-2
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... antidepressant drugs trazodone, nefazodone and etoperidone and of the minor tranquillizer mepiprazole (Rotzinger et al., 1998). Its chemical name is 1-(3-chlorophenyl)piperazine and the chemical formula is C10H13ClN2 (Reynolds, 1996). From September 2004 until April 2005, DIMS registered mCPP 25 tim ...
Clinical pharmacology of anti-infectives and nonsteroidal_англ
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A Mechanistic Approach to Understanding the Factors Affecting

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A Warning on Gemcitabine Generics Used For

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Successful cases of Traceability in the Healthcare Sector in
Successful cases of Traceability in the Healthcare Sector in

... terms established by the regulations in force in each particular case. Thus, it is guaranteed that the product distribution chain develops the necessary steps to achieve the final objective, which is to reach the community with a controlled product during all its process, from the manufacture to its ...
POLIGUGUL COMPLEX
POLIGUGUL COMPLEX

... molecular weight alcohols isolated from sugar cane, helps reduce cholesterol levels by inhibiting its synthesis within the body. In test tube studies, scientists observed that policosanol also enhanced processing of LDL cholesterol. A review of scientific literature published in the February 2002 ed ...
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Liposome- A Versatile Drug Delivery System
Liposome- A Versatile Drug Delivery System

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13274025
13274025

... The sincere and relentless effort of the R& D team has taken the company a step further through introduction of high tech Anti-AIDS and Anti-cancer products in the recent years. A good number of APLs are also in the development pipeline to ensure availability of raw materials in the post WTO era. Wi ...
Situation Report National Drug Intelligence Center Synthetic Cathinones (Bath Salts):
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Interactive Association of Drugs Binding to Human
Interactive Association of Drugs Binding to Human

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ADHD drugs compared - Consumer Health Choices
ADHD drugs compared - Consumer Health Choices

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Chemistry, Drugs and Clandestine Laboratories
Chemistry, Drugs and Clandestine Laboratories

... pseudoephedrine with hydriodic acid and red phosphorus , commonly known as “HI/Red P”, and is relatively simple. • In New Zealand the most routinely encountered method is the reduction of pseudoephedrine with hypophosphorous acid and iodine or red phosphorus with iodine and water. These are variatio ...
Factors that affect mass transport from drug eluting stents into the
Factors that affect mass transport from drug eluting stents into the

... infarction and death are lower when DES are used [42,43] while other studies suggest that DES and BMS perform similarly [44]. The contrasting outcomes from such trials raise questions regarding the effectiveness of DES which has resulted in an increased effort by researchers to develop a means of pr ...
Population Pharmacokinetics
Population Pharmacokinetics

... subject to ethical research of high quality  ensure that medicines for children are appropriately authorised  improve the information available on the use of medicinal products in the various paediatric populations  The above objectives should be achieved without subjecting the paediatric populat ...
American Geriatrics Society 2015 Updated Beers Criteria for
American Geriatrics Society 2015 Updated Beers Criteria for

... A panel with expertise in geriatric medicine, nursing, pharmacy practice, research, and quality measures was convened comprising members of the previous panel and new members. Other factors that influenced selection of panel members were the desire to have interdisciplinary representation, a range o ...
MODERN TASTE CONCEALING TECHNIQUES IN
MODERN TASTE CONCEALING TECHNIQUES IN

... B) Core material phase –The process consists of depositing the liquid polymer coating upon the core material. This is accomplished by controlled, physical mixing of the coating material and the core material in the manufacturing vehicle. Deposition of the liquid polymer coating around the core mater ...
10.4103-0975-1483.93570
10.4103-0975-1483.93570

... Preparation of standard Dissolved an accurately weighed quantity 20 mg of USP cephalexin reference standard with water in a 100 ml standard ask. The solution was sonicated and ltered to obtain the standard solution. Assay preparation and procedure Twenty tablets were weighed and nely powdered. An ac ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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