Misc topic, Medicine and Drugs
... cells by binding to specific receptor molecules (the "lock"), which are often located in the cell membrane. This binding "unlocks" the cell's response, so that the hormone or neurotransmitter can exert its effects. Many drugs work by mimicking a naturally occurring hormone or neurotransmitter in the ...
... cells by binding to specific receptor molecules (the "lock"), which are often located in the cell membrane. This binding "unlocks" the cell's response, so that the hormone or neurotransmitter can exert its effects. Many drugs work by mimicking a naturally occurring hormone or neurotransmitter in the ...
AstraZeneca Crestor citizen petition 05 31 2016
... C. Background On The Development Of Rosuvastatin For Use In The Treatment Of The Pediatric Orphan HoFH Population In 2014, AstraZeneca initiated a trial of rosuvastatin in pediatric patients with HoFH ages 6 to 17 to address unmet medical needs of pediatric HoFH patients. Among other things, the stu ...
... C. Background On The Development Of Rosuvastatin For Use In The Treatment Of The Pediatric Orphan HoFH Population In 2014, AstraZeneca initiated a trial of rosuvastatin in pediatric patients with HoFH ages 6 to 17 to address unmet medical needs of pediatric HoFH patients. Among other things, the stu ...
Drug situation in Georgia
... positive changes achieved within the framework of the programme. The National Focal Point on Drug Information is just such an important institutional coordination unit set up within the framework of the Southern Caucasus Anti Drug Programme. This service has been regularly monitoring the drug situat ...
... positive changes achieved within the framework of the programme. The National Focal Point on Drug Information is just such an important institutional coordination unit set up within the framework of the Southern Caucasus Anti Drug Programme. This service has been regularly monitoring the drug situat ...
formulation and evalution of medicated chewing gum of
... Chewing Gum has been used for centuries to clean the mouth and freshen breath. Medicated Chewing Gums are solid, single dose preparations with a base consisting mainly of gum that is intended to be chewed but not swallowed. They contain one or more active substance which released by chewing and are ...
... Chewing Gum has been used for centuries to clean the mouth and freshen breath. Medicated Chewing Gums are solid, single dose preparations with a base consisting mainly of gum that is intended to be chewed but not swallowed. They contain one or more active substance which released by chewing and are ...
local drug delivery systems in the treatment of
... Periodontitis, a disease involving supportive structures of the teeth prevails in all groups, ethnicities, races and both genders. It is a localised inflammatory response caused by bacterial infection of a periodontal pocket associated with subgingival plaque. Periodontal diseases include conditions ...
... Periodontitis, a disease involving supportive structures of the teeth prevails in all groups, ethnicities, races and both genders. It is a localised inflammatory response caused by bacterial infection of a periodontal pocket associated with subgingival plaque. Periodontal diseases include conditions ...
scheme of examination - Guru Gobind Singh Indraprastha University
... Significance of quantitative analysis in quality control, Different techniques of analysis, Preliminaries and definitions, Significant figures, Rules for retaining significant digits, Types of errors, Mean deviation, Standard deviation, Statistical treatment of small data sets, Selection of sample ...
... Significance of quantitative analysis in quality control, Different techniques of analysis, Preliminaries and definitions, Significant figures, Rules for retaining significant digits, Types of errors, Mean deviation, Standard deviation, Statistical treatment of small data sets, Selection of sample ...
Drug Regulation: History, Present and Future
... demand for drugs. In many countries, relevant provisions regarding such control measures have been stipulated in legislation. For example, only product information approved during the registration process can be included in the package inserts, leaflets or promotional materials. Regulatory or legal ...
... demand for drugs. In many countries, relevant provisions regarding such control measures have been stipulated in legislation. For example, only product information approved during the registration process can be included in the package inserts, leaflets or promotional materials. Regulatory or legal ...
OVERVIEW OF CHIRALITY AND CHIRAL DRUGS
... and therefore affords superior atom economy. It has become the most powerful and commonly employed method for preparation of chiral drugs. Since the 1980s, there has been progress in many new technologies, in particular, the technology related to catalytic asymmetric synthesis, that allow the prepar ...
... and therefore affords superior atom economy. It has become the most powerful and commonly employed method for preparation of chiral drugs. Since the 1980s, there has been progress in many new technologies, in particular, the technology related to catalytic asymmetric synthesis, that allow the prepar ...
A c a d
... Conventional eye drops currently account for more than 90% of the marketed ophthalmic formulations1. However, after instillation of an eye drop, typically less than 5% of the applied drug penetrates the cornea and reaches the intraocular tissues. This is due to the rapid and extensive precorneal los ...
... Conventional eye drops currently account for more than 90% of the marketed ophthalmic formulations1. However, after instillation of an eye drop, typically less than 5% of the applied drug penetrates the cornea and reaches the intraocular tissues. This is due to the rapid and extensive precorneal los ...
CRS Newsletter. Volume 25, Number 2. 2008
... paediatric patients, generally considered a more vulnerable population, to an increased risk of adverse events. As such, paediatrics represents a neglected patient population, both in terms of clinical efficacy and safety data, as well as the availability of medical advances, including controlled re ...
... paediatric patients, generally considered a more vulnerable population, to an increased risk of adverse events. As such, paediatrics represents a neglected patient population, both in terms of clinical efficacy and safety data, as well as the availability of medical advances, including controlled re ...
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... more individuals - pilots, train engineers, and motor vehicle operators will be traveling more miles with greater exposure to the dangers of psychoacti ve drug use and misuse. The need to educate the public about drugs and vehicle operation is obvious. Alcohol is the most widely used psy<..:hoacti v ...
... more individuals - pilots, train engineers, and motor vehicle operators will be traveling more miles with greater exposure to the dangers of psychoacti ve drug use and misuse. The need to educate the public about drugs and vehicle operation is obvious. Alcohol is the most widely used psy<..:hoacti v ...
pdf
... main giant component was observed, which contained 258 targets. Within it, protein family members were mostly clustered in different neighborhoods: cholinergic nicotinic receptor subunits (CHRN), type A γ-aminobutyric acid receptor subunits (GABR), voltage-gated sodium channel subunits (SCN), voltag ...
... main giant component was observed, which contained 258 targets. Within it, protein family members were mostly clustered in different neighborhoods: cholinergic nicotinic receptor subunits (CHRN), type A γ-aminobutyric acid receptor subunits (GABR), voltage-gated sodium channel subunits (SCN), voltag ...
MULTIPLE UNIT EXTENDED RELEASE PELLETS OF PROPRANOLOL HYDROCHLORIDE: PREPARATION AND CHARACTERIZATION
... The purpose of the present study is to develop and investigate the invitro performance of multiple unit extended release pellets of a model drug, Propranolol Hydrochloride (PPNL HCl) with extreme water solubility , short half-life that provides an effective blood pressure control in hypertension and ...
... The purpose of the present study is to develop and investigate the invitro performance of multiple unit extended release pellets of a model drug, Propranolol Hydrochloride (PPNL HCl) with extreme water solubility , short half-life that provides an effective blood pressure control in hypertension and ...
PDF - World Journal of Pharmaceutical Sciences
... Ketorolac tromethamine is a potent non-steroidal drug with potent analgesic and anti-inflammatory activity. Its oral administration is associated with a high risk of adverse effects such as irritation, ulceration and bleeding of gastrointestinal tract. The present study focuses on the development of ...
... Ketorolac tromethamine is a potent non-steroidal drug with potent analgesic and anti-inflammatory activity. Its oral administration is associated with a high risk of adverse effects such as irritation, ulceration and bleeding of gastrointestinal tract. The present study focuses on the development of ...
protocol - Rajiv Gandhi University of Health Sciences
... dosage form. It opens the doors for new inventions and patents. Many techniques have been developed which not only improve the taste of molecule but also the formulation and performance of the molecule. The main objective of present review is to explore different method, technologies and evaluation ...
... dosage form. It opens the doors for new inventions and patents. Many techniques have been developed which not only improve the taste of molecule but also the formulation and performance of the molecule. The main objective of present review is to explore different method, technologies and evaluation ...
In vitro and in vivo evaluation of a new sublingual tablet system for
... (maximum 3 ml, corresponding to 150 g fentanyl base) was placed under the patient’s tongue; for most patients (82%), an analgesic effect was obtained after 10–15 min. However, some patients found it difficult to retain the solution under the tongue and swallowed it. Weinberg et al. (1988) used a so ...
... (maximum 3 ml, corresponding to 150 g fentanyl base) was placed under the patient’s tongue; for most patients (82%), an analgesic effect was obtained after 10–15 min. However, some patients found it difficult to retain the solution under the tongue and swallowed it. Weinberg et al. (1988) used a so ...
In the scientific literature, which countries first appeared term
... E. means that events occurring outside the living organism ANSWER: A What is meant when using the term physical state of drugs? A. amorphous B. form crystals C. nature of the crystals D. dispersion E. amorphous, form crystals, nature of the crystals ANSWER: E What is meant when using the term physic ...
... E. means that events occurring outside the living organism ANSWER: A What is meant when using the term physical state of drugs? A. amorphous B. form crystals C. nature of the crystals D. dispersion E. amorphous, form crystals, nature of the crystals ANSWER: E What is meant when using the term physic ...
INVITRO TARTRATE Research Article
... The moisture uptake studies give an indication about the relative moisture absorption capacities of polymers and an idea whether the formulations maintain their integrity after absorption of moisture. The study was carried out as per procedure reported earlier (Velmuruga ...
... The moisture uptake studies give an indication about the relative moisture absorption capacities of polymers and an idea whether the formulations maintain their integrity after absorption of moisture. The study was carried out as per procedure reported earlier (Velmuruga ...
Read "FDA Violation of the Rule of Law"
... Kefauver-Harris Drug Amendments became law in 1962. Under the 1938 Act, NDAs were approved unless FDA acted to deny them. Under the 1962 Act, NDAs were denied unless FDA acted to approve them. For an NDA to be granted, FDA had to conclude that the new drug was safe and effective. With the support of ...
... Kefauver-Harris Drug Amendments became law in 1962. Under the 1938 Act, NDAs were approved unless FDA acted to deny them. Under the 1962 Act, NDAs were denied unless FDA acted to approve them. For an NDA to be granted, FDA had to conclude that the new drug was safe and effective. With the support of ...
under Modified BVoc Regulations 2014
... a) Antihypertensives b) Anti-anginal drugs c) Anti-arrhythmic drugs d) Drugs used for therapy of Congestive Heart Failure e, Antilipidermic drugs f) Cardiotonic drugs (discuss only general action,eg,therapeutic use,dose and mode of administration and adverse effect ) ...
... a) Antihypertensives b) Anti-anginal drugs c) Anti-arrhythmic drugs d) Drugs used for therapy of Congestive Heart Failure e, Antilipidermic drugs f) Cardiotonic drugs (discuss only general action,eg,therapeutic use,dose and mode of administration and adverse effect ) ...
Polysaccharides Based Colon Specific Drug delivery: A
... biodegradable hydrogel formation, which was able to retain poorly water-soluble drug. Krishnaiah etal,61 studied the influence of metronidazole and tinidazole on the usefulness of guar gum, a colon-specific drug carrier. Compression coated tablets62 of 5-ASA and matrix tablets of mebendazole have be ...
... biodegradable hydrogel formation, which was able to retain poorly water-soluble drug. Krishnaiah etal,61 studied the influence of metronidazole and tinidazole on the usefulness of guar gum, a colon-specific drug carrier. Compression coated tablets62 of 5-ASA and matrix tablets of mebendazole have be ...
Nomenclature Guideline Outline
... FDCA 502(e)(3) specifies how “established names” for drugs are created. FDA may designate such names by regulation under FDCA 508, but rarely does so. Instead, in the absence of a name specifically designated in a 508 rulemaking, the law recognizes the official title of a drug in USP-NF as the estab ...
... FDCA 502(e)(3) specifies how “established names” for drugs are created. FDA may designate such names by regulation under FDCA 508, but rarely does so. Instead, in the absence of a name specifically designated in a 508 rulemaking, the law recognizes the official title of a drug in USP-NF as the estab ...
Nomenclature Guideline Outline
... FDCA 502(e)(3) specifies how “established names” for drugs are created. FDA may designate such names by regulation under FDCA 508, but rarely does so. Instead, in the absence of a name specifically designated in a 508 rulemaking, the law recognizes the official title of a drug in USP-NF as the estab ...
... FDCA 502(e)(3) specifies how “established names” for drugs are created. FDA may designate such names by regulation under FDCA 508, but rarely does so. Instead, in the absence of a name specifically designated in a 508 rulemaking, the law recognizes the official title of a drug in USP-NF as the estab ...
Drug action
... Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. Some material was previously published. ...
... Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. Some material was previously published. ...
A Review on Benzylpiperazine and Trifluoromethylphenypiperazine
... to metabolize BZP according to Gee and Fountain (2007) (Gee and Fountain 2007), supported by Staack et al. (2002) who did a research on the metabolism and toxicological detection of the Nbenzylpiperazine metabolites in human and rat urine, and found out that 4-hydroxy-BZP, 3‟hydroxy-BZP, piperazine, ...
... to metabolize BZP according to Gee and Fountain (2007) (Gee and Fountain 2007), supported by Staack et al. (2002) who did a research on the metabolism and toxicological detection of the Nbenzylpiperazine metabolites in human and rat urine, and found out that 4-hydroxy-BZP, 3‟hydroxy-BZP, piperazine, ...