• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
printable PDF - Edison Investment Research
printable PDF - Edison Investment Research

... on naturally occurring ‘endogenous’ ligands (such as peptide hormones), ie there are multiple potential starting points to develop safer and more effective compounds. This information is then used to design multiple molecules with better affinity and selectivity, from which a lead candidate, or inde ...
Prescription Drug Use Among Midlife and Older Americans
Prescription Drug Use Among Midlife and Older Americans

... representative of the targeted population. Weights were applied to the data to make sure that the sample reflects the U.S. Census statistics for adults age 50 years of age or older by age within sex and region criteria. The sampling error for the general population is +/3 percentage points at the 95 ...
Formulation and Evaluation of sustained release Pellets of
Formulation and Evaluation of sustained release Pellets of

... ratios. Also, resistance to the external factors such ...
The most important side effect of interferon gamma is
The most important side effect of interferon gamma is

... If a patient misses three doses of their daily drug, which is the best solution? a) Prescribe a higher dosage pill so missed doses will have less effect b) Setup an appointment to have the patient evaluated c) Do nothing and continue normal regimen d) Wait 3 more days (week total) then return to nor ...
12146039
12146039

... I would like to express my thanks and gratitude to the Department of Pharmacy, BRAC University for providing me the laboratory facilities for the completion of the project. I am also thankful to my supervisor, Mrs. Shahana Sharmin for her dedicated supervision and at the same time, I am grateful for ...
Evaluating Statin Drugs To Treat
Evaluating Statin Drugs To Treat

... Statins are used to lower high cholesterol to help prevent heart disease, which can lead to heart attacks, heart failure, and death. Heart disease is the leading cause of death in the U.S., accounting for more than 631,000 deaths in 2006, the most recent year for which figures are available, accordi ...
SEMINAR ON BUCCAL DRUG DELIVERY SYSTUM
SEMINAR ON BUCCAL DRUG DELIVERY SYSTUM

... -ORA-VESCENT :This drug delivery system have been designed to promote drug absorption through oral mucosa(buccal)  This may enable more rapid absorption of drug that have a long Tmax.  In case where the patient is vomiting frequently. Or in migraine gastric transit may be so severely compromised. ...
Enhancement of Dissolution Rate of Ritonavir: A Comparative
Enhancement of Dissolution Rate of Ritonavir: A Comparative

... demonstrating that the reaction became more favorable as the concentration of carrier increased. In vitro Dissolution Studies: All formulations of Ritonavir were subjected to in vitro dissolution studies using 0.1N HCl as the dissolution medium to assess various dissolution properties. All SD formul ...
STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 
STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 

... were  added  as  500:125,  1000:250  and  1500:375  µg/ml  of  Telmisartan and Ramipril respectively. The peak areas of these three  ...
A Systematic Review on Advanced Drug Delivery Technologies to
A Systematic Review on Advanced Drug Delivery Technologies to

... lymphoedema again classified into lymphedema congenita, lymphoedema praecox and lymphoedema tarda. Lymphedema congenita is a severe form of lymphoedema. Secondary lymphoedema is caused by acquired lymphatic obstruction which in turn is caused by infiltration of regional nodes by tumor, surgical exci ...
Pharmaceutical excipients and pediatric formulations
Pharmaceutical excipients and pediatric formulations

... Similarly, distribution of drugs can be severely impacted in pediatric reactions. The interactions thus produced due to drug-excipient, sub-population as the amount of body water is significantly higher excipient-excipient, or excipient-intracellular chemicals can be in neonates (85 percent) as comp ...
House Holds Hearing on FDA`s Authority over Compounding
House Holds Hearing on FDA`s Authority over Compounding

... Congressman Waxman of California echoed this concern, stating that Congress needs to “pass legislation that clearly delineates who is in charge of what.”28 Other Subcommittee members argued that FDA already has authority to act. Subcommittee Vice Chair Michael C. Burgess, M.D. (R-TX) stated that the ...
Protecting Public Health from Outside the Physician`s Office: A
Protecting Public Health from Outside the Physician`s Office: A

... highly regulated by the public sector. The United States Food and Drug Administration (FDA) is an agency of the United States Department of Health and Human Services, authorized by Congress to promote the safety and efficiency of prescription drugs and medical devices placed on the U.S. market.3 The ...
substance abuse - Nurses Learning Network
substance abuse - Nurses Learning Network

... involves using illegal as well as legal mind-changing Asocial@ drugs that lead to ill effects and undesirable consequences. It also includes the use of legal medicines by health people for social convenience or personal pleasure, and the use of typically nondrug substances, such as gasoline, to prod ...
Pharmacovigilance of drug allergy and hypersensitivity using
Pharmacovigilance of drug allergy and hypersensitivity using

... drug allergy/hypersensitivity and the allergological examination includes in vivo and in vitro tests selected on the basis of clinical features (18). Prick, intradermal and patch tests are the most readily available forms of allergy testing but, for many drugs, have not been standardized. The determ ...
Current Drugs for Antimalarial Chemoprophylaxis: A Review of
Current Drugs for Antimalarial Chemoprophylaxis: A Review of

... drug-resistant malaria strains contribute to the current recommendations concerning malaria chemoprophylaxis. Chloroquine (e.g., Aralen), the former standard for malaria prevention and treatment, is now effective only in limited areas, and multidrug resistance has made chemoprophylaxis with mefloqui ...
Interactions between Grapefruit Juice and Calcium Channel
Interactions between Grapefruit Juice and Calcium Channel

... The extent of interaction between calcium channel antagonists and grapefruit juice varies widely among drugs. Coadministration of calcium channel antagonists with grapefruit juice can elevate the bioavailability of drugs and alter pharmacokinetic parameters of the drug. A calcium channel antagonist ...
sustained and controlled drug delivery system - as a part
sustained and controlled drug delivery system - as a part

... formulations. Oral controlled release drug delivery is a drug delivery system that provides the continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specif ...
www.ijpbs.com Rishikesh S Deshmukh*et al Int J Pharm Bio Sci
www.ijpbs.com Rishikesh S Deshmukh*et al Int J Pharm Bio Sci

... use of these metallic compounds. The synthetic dyes were much brighter, cheaper, more uniform, more stable (in their reactions to high processing temperatures, acids, carbon dioxide, storage and light) and more potent (i.e., less could be used to gain the same effect) than anything seen before, and ...
university of california student prescription drug plan
university of california student prescription drug plan

... pharmacy, where available (students only), a retail program with network retail pharmacies (“Network Pharmacy”), out-of-network retail pharmacies (”Out-of-Network Pharmacy”) and, where available, a mail order option. A Network Pharmacy has a contract with the Claims Administrator to dispense drugs t ...
DEPARTMENT OF HEALTH AND HUMAN SERVICES Jul - ~ ~~0;1n
DEPARTMENT OF HEALTH AND HUMAN SERVICES Jul - ~ ~~0;1n

... Mandates Reform Act of 1995 (Public LatitiF 104-4) . Executive Order 12d66 directs agencies to assess all,_costs ,and benefits of available regulatory alternatives and, when regulation is necessary, to select regulatory approaches that maximize net benefits (including potential economic, environment ...
The effects of herbal teas on drug permeability
The effects of herbal teas on drug permeability

... Inhibition and induction of the metabolic enzyme CYP can also affect the pharmacokinetics of treatment with these medications. This should be of concern since CYP3A4 is associated with the metabolism of many drugs. It is well known that there is overlap in the substrate specificities of CYP3A4 and P ...
From Molecule to Dose Form – Accelerated Bioavailability
From Molecule to Dose Form – Accelerated Bioavailability

... very often applied. Eventually, the aim might also be to keep the concentration of dissolved drug in the surrounding bulk fluid low, e.g. by facilitating the subsequent drug transport away from its site of dissolution. On the other hand, the thickness of the liquid, unstirred boundary layer as well ...
Asthma Medications
Asthma Medications

... Corticosteroids for asthma are typically available as handheld inhalers containing liquid or powder. Many inhaled products have specific devices, and you should be thoroughly informed on how to use the inhaler prescribed for you. Frequency of administration (how often you use the inhaler) depends on ...
PREPARATION AND COMPARATIVE EVALUATIONOF LIQUISOLID COMPACT AND SOLID
PREPARATION AND COMPARATIVE EVALUATIONOF LIQUISOLID COMPACT AND SOLID

... produces cough, adversely affect lipid profile and rebound hypertension after discontinuation. These adverse effects can be overcome by using angiotensin II receptor antagonists[2].Clinical trials indicates that candesartan cilexetilis effective and safe in the treatment of hypertension[3].The solub ...
< 1 ... 9 10 11 12 13 14 15 16 17 ... 161 >

Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report