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Mixing and compatibility guide for commonly used aerosolized
Mixing and compatibility guide for commonly used aerosolized

... therapy.1,2 On the other hand, compatibility information for inhaled aerosolized medications is limited.3,4 A compatibility chart can potentially save time by answering the most common questions about admixtures. A chart can provide a quick and easy reference for medical personnel about compatibilit ...
GHB - Center for Substance Abuse Research
GHB - Center for Substance Abuse Research

... As a result, there is no definitive way for users to know how strong a particular form of GHB is, thereby increasing the risk of an overdose. Powder forms of GHB are not as prevalent as liquid forms, yet the method of use is nearly identical. GHB and Date Rape GHB can be both an odorless, colorless ...
Pravin R - Pivot Pharmaceuticals
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... Build and enhance the pipeline value of the company through development of early-stage preclinical assets of the company across GI, diabetes and cancer areas Integrated all the scientific and operational activities of the company across multiple sites in the United States and in India Led the Joint ...
International Journal of Biomedical and Advance Research
International Journal of Biomedical and Advance Research

... Polymer matrix / Drug reservoir: Polymers are the backbone of TDDS, which control the release of the drug from the device. Polymer matrix can be prepared by dispersion of drug in liquid or solid state synthetic polymer base. Polymers used in TDDS should have biocompatibility and chemical compatibili ...
Alcohol and Other Drugs Alcohol and Other Drugs
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... The Club Champions program is a $2 million initiative of the Commonwealth Government’s National Binge Drinking Strategy to equip sportspeople to promote responsible attitudes and practices towards alcohol. A National Alcohol Code of Conduct underpins the Club Champions Program. In 2009, seven sporti ...
Controlling drug delivery chapter 1 Over view
Controlling drug delivery chapter 1 Over view

... and intraperitoneal administration. Usually aqueous solutions are used for intravenous delivery, but it is also possible that the dosage form contains a dispersed phase (solid or liquid), provided the dispersed particles are small enough (e.g. smaller than 100–150 nm) to avoid embolism. For other ro ...
Controlling drug delivery
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... sprays, to name a few. If drug delivery systems are designed to give a local drug effect and not systemic activity, they can be described as topical delivery systems. This is the case for many dermal dosage forms. ...
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Hatch-Waxman Turns 30 - Yale Law School Legal Scholarship
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Antimalarial Drug Combination Therapy
Antimalarial Drug Combination Therapy

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RECENT TECHNOLOGIES FOR THE TASTE MASKING OF BITTER
RECENT TECHNOLOGIES FOR THE TASTE MASKING OF BITTER

... obnoxious drugs has gained the importance as the most of them are administered orally. This reason is an initiative for the development of various taste masking technologies by which the characteristics of the dosage form is improved and good patient compliance is achieved. The main objective of thi ...
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amphetamines and other stimulants history

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IN VITRO MICROSPHERES
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... greatly limited the in vivo antitumor efficacy and clinical application of the drug. The current research work aimed to solve this problem by preparing sustained release microspheres where the drug encapsulated into bovine serum albumin, a biocompatible, nontoxic and non immunogenic drug carrier. Mi ...
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Drugs: Safety and Effectiveness
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... acts through its postmarket or post-approval regulatory procedures. This report is a primer on drug approval and regulation: it describes (1) how drugs are approved and come to market, including FDA’s role in that process and (2) FDA and industry roles once drugs are on the pharmacy shelves. ...
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... synthetic biology to reach its full potential, it is not enough to be able to synthesize whole genomes; it will also be necessary to program those genomes to perform some desired molecular function. Using single genes as modular units, synthetic biologists are in the process of creating component li ...
Registration process of API - International Journal of Pharma
Registration process of API - International Journal of Pharma

... intended to be used in the manufacture of a drug (medicinal) product and that, when used in the production of a drug, becomes an active ingredient of the drug product. Such substances are intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatmen ...
Metabolism and drug interactions of 3-hydroxy-3
Metabolism and drug interactions of 3-hydroxy-3

... and mortality was signi®cantly reduced [1, 2, 3, 4, 5]. Although these drugs are generally well tolerated, adverse events are associated with their short- and long-term use and especially with concomitant therapy leading to myopathy and potentially fatal rhabdomyolysis [6, 7, 8, 9, 10, 11]. Since th ...
Answer the following questions
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... 1- False negative results may be obtained in Brucella agglutination test. 2- Bacillus anthracis can be chosen as a weapon of bioterrorism. 3- Loss of certain antigen may be associated with loss of virulence. 4- Living attenuated vaccine is superior than inactivated vaccine. 5- L-forms of bacteria ar ...
SEMINAR ON - Pharmawiki.in
SEMINAR ON - Pharmawiki.in

... New and developing approach to deliver drugs to the brain. Improved delivery to the brain via the IN route has been reported for some low-mol.wt drugs as well as therapeutic peptides and proteins . Nose to brain delivery has been reported either in humans or animal models of Alzheimer’s disease, ...
estimation of percent purity of alprazolam tablet of different market
estimation of percent purity of alprazolam tablet of different market

... A drug can be defined as a natural or synthetic substance that is used to produce physiological effect in man. But in modern context drugs mean something different to each person. To some, drugs are necessity for sub staining and prolonging life; to others drugs provide an escape from the pressures ...
Demand reduction: A glossary of terms
Demand reduction: A glossary of terms

... UNITED NATIONS PUBLICATION Sales No. E.00.XI.9 ISBN: 92-1-148129-5 ...
BAOJ Pharmaceutical Sciences
BAOJ Pharmaceutical Sciences

... the gastrointestinal contents, poor membrane permeability, or presystemic metabolism. Compounds can have poor membrane permeation due to large-molecular weight, as is the case with proteins and other macromolecules, or insufficient lipophilicity to partition into biological membranes, as with many h ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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