Molecular Characterization of the Melanin
... ligand and the helical model of the human MCH receptor were constructed separately, then docked together as described in Materials and Methods. The receptor model contains two discrete hydrophilic pockets, one between transmembrane domains 3 and 7 and the other between transmembrane domains 4, 5, an ...
... ligand and the helical model of the human MCH receptor were constructed separately, then docked together as described in Materials and Methods. The receptor model contains two discrete hydrophilic pockets, one between transmembrane domains 3 and 7 and the other between transmembrane domains 4, 5, an ...
The ARP2/3 complex: giving plant cells a leading edge
... (locomotion).(1) However, when a cell becomes encased in an exocyst or a cell wall, as occurs in many fungi and plant cells, it loses both its flexibility of form as well as the capacity for locomotion. Walled cells, therefore, unless equipped with special locomotor organs, can only grow towards or ...
... (locomotion).(1) However, when a cell becomes encased in an exocyst or a cell wall, as occurs in many fungi and plant cells, it loses both its flexibility of form as well as the capacity for locomotion. Walled cells, therefore, unless equipped with special locomotor organs, can only grow towards or ...
The Antiallergic Mast Cell Stabilizers Lodoxamide and Bufrolin as
... signals obtained using GPR35b were substantially lower than when using GPR35a. ...
... signals obtained using GPR35b were substantially lower than when using GPR35a. ...
The epidermal intermediate filament proteins of
... epidermal keratin diseases (Fuchs and Cleveland, 1998). The common structural principle of all IF proteins is a central alpha helical rod domain, able to form double stranded coiled coils, Prof. Dr. Klaus Weber, Max Planck Institute for Biophysical Chemistry, Department of Biochemistry, Am Fassberg ...
... epidermal keratin diseases (Fuchs and Cleveland, 1998). The common structural principle of all IF proteins is a central alpha helical rod domain, able to form double stranded coiled coils, Prof. Dr. Klaus Weber, Max Planck Institute for Biophysical Chemistry, Department of Biochemistry, Am Fassberg ...
Gene Expression Profiling During Asexual Development of the Late
... modulation is greater because numerous genes exhibit incremental changes. For example, the abundance of some mRNAs is very low in hyphae, intermediate in sporangia, and high during zoosporogenesis. When maximum fold changes over the entire life cycle are calculated, 14% of genes or 1,608 vary >128-f ...
... modulation is greater because numerous genes exhibit incremental changes. For example, the abundance of some mRNAs is very low in hyphae, intermediate in sporangia, and high during zoosporogenesis. When maximum fold changes over the entire life cycle are calculated, 14% of genes or 1,608 vary >128-f ...
Cell wall-deficient, L-form bacteria in the 21st century: a personal
... [18]) and began investigating its properties. Working with the strain was frustrating because it was tricky to grow (e.g. requiring osmotically supportive medium) but also because our attempts to introduce fluorescent (GFP) markers or other genetic changes that would help us to study its properties c ...
... [18]) and began investigating its properties. Working with the strain was frustrating because it was tricky to grow (e.g. requiring osmotically supportive medium) but also because our attempts to introduce fluorescent (GFP) markers or other genetic changes that would help us to study its properties c ...
Going from where to why—interpretable
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
The Antiallergic Mast Cell Stabilizers Lodoxamide and Bufrolin as
... signals obtained using GPR35b were substantially lower than when using GPR35a. ...
... signals obtained using GPR35b were substantially lower than when using GPR35a. ...
Fulltext PDF - Indian Academy of Sciences
... Characterization of the ppGpp0 strain showed it to filament upon nutritional down shift, suggesting a role for (p)ppGpp in the process of cell division (Xiao et al. 1991). Insights of its role in cell division came from the studies carried out in the D’Ari lab to understand the function of PBP2 (pen ...
... Characterization of the ppGpp0 strain showed it to filament upon nutritional down shift, suggesting a role for (p)ppGpp in the process of cell division (Xiao et al. 1991). Insights of its role in cell division came from the studies carried out in the D’Ari lab to understand the function of PBP2 (pen ...
Protein secretion and surface display in Gram
... The cell wall peptidoglycan of Gram-positive bacteria functions as a surface organelle for the transport and assembly of proteins that interact with the environment, in particular, the tissues of an infected host. Signal peptide-bearing precursor proteins are secreted across the plasma membrane of G ...
... The cell wall peptidoglycan of Gram-positive bacteria functions as a surface organelle for the transport and assembly of proteins that interact with the environment, in particular, the tissues of an infected host. Signal peptide-bearing precursor proteins are secreted across the plasma membrane of G ...
1 MB - Columbia University
... et al., 2005; Takashima et al., 2007) but not in hot nociceptors (Kobayashi et al., 2005), these results suggest that the coding of temperature may be orchestrated by the activity of dedicated cell types, each tuned to respond to a defined temperature range (Lumpkin and Caterina, 2007). ...
... et al., 2005; Takashima et al., 2007) but not in hot nociceptors (Kobayashi et al., 2005), these results suggest that the coding of temperature may be orchestrated by the activity of dedicated cell types, each tuned to respond to a defined temperature range (Lumpkin and Caterina, 2007). ...
A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila. Nature Cell Biology 3, 848-851. pdf
... membrane proteins, so they can influence chromosome organization and possibly gene expression6,10,16. gurken transcripts are synthesized in the oocyte nucleus and must interact with the Squid hnRNP protein and possibly K10, a putative RNA-binding protein, in order to localize properly after export i ...
... membrane proteins, so they can influence chromosome organization and possibly gene expression6,10,16. gurken transcripts are synthesized in the oocyte nucleus and must interact with the Squid hnRNP protein and possibly K10, a putative RNA-binding protein, in order to localize properly after export i ...
PDF
... morphogenetic behaviors that includes epithelial-mesenchymal transition, directional cell migration and cell-cell fusion (Wilt and Ettensohn, 2007; Ettensohn, 2009). These cellular behaviors have been analyzed in remarkable detail, largely owing to the optical transparency of the sea urchin embryo a ...
... morphogenetic behaviors that includes epithelial-mesenchymal transition, directional cell migration and cell-cell fusion (Wilt and Ettensohn, 2007; Ettensohn, 2009). These cellular behaviors have been analyzed in remarkable detail, largely owing to the optical transparency of the sea urchin embryo a ...
A Nascent Membrane Protein Is Located Adjacent to ER Membrane
... membrane was investigated by photocrosslinking. Nascent polypeptides of different lengths, each containing a single IgM transmembrane sequence that functions either as a stop-transfer or a signal-anchor sequence, were synthesized by in vitro translation of truncated mRNAs in the presence of N~-(5-az ...
... membrane was investigated by photocrosslinking. Nascent polypeptides of different lengths, each containing a single IgM transmembrane sequence that functions either as a stop-transfer or a signal-anchor sequence, were synthesized by in vitro translation of truncated mRNAs in the presence of N~-(5-az ...
The nucleolus and herpesviral usurpation
... CSIG), and B23 (Pederson & Tsai, 2009). N-acetyltransferase 10 (NAT10), which has been shown to play a role in maintaining or enhancing the stability of a-tubulin, also influences the cell cycle. The depletion of NAT10 induces defects in nucleolar assembly and cytokinesis and decreases acetylated a- ...
... CSIG), and B23 (Pederson & Tsai, 2009). N-acetyltransferase 10 (NAT10), which has been shown to play a role in maintaining or enhancing the stability of a-tubulin, also influences the cell cycle. The depletion of NAT10 induces defects in nucleolar assembly and cytokinesis and decreases acetylated a- ...
Reddy, Kirthi: Analysis of Caenorhabditis elegans protein T09E8.2
... with the BLOCKS search, and the biological significance of this hit was discussed above. The second hit found, GTP-binding nuclear protein Ran family, had a probability of 9.88e-9. The expect value calculated for this is 0.33 which, again, is not statistically significant. This domain has been found ...
... with the BLOCKS search, and the biological significance of this hit was discussed above. The second hit found, GTP-binding nuclear protein Ran family, had a probability of 9.88e-9. The expect value calculated for this is 0.33 which, again, is not statistically significant. This domain has been found ...
SQA Higher Biology Unit 1 Cell Biology
... ¯ Some organisms are unicellular. ¯ Unicellular organisms can be either plant or animal cells. ¯ Some organisms are multicellular. ¯ Multicellular organisms can be either plants or animals. ¯ Multicellular organisms are organised into tissues, organs and systems, to function more effectively. ...
... ¯ Some organisms are unicellular. ¯ Unicellular organisms can be either plant or animal cells. ¯ Some organisms are multicellular. ¯ Multicellular organisms can be either plants or animals. ¯ Multicellular organisms are organised into tissues, organs and systems, to function more effectively. ...
A Nascent Membrane Protein Is Located Adjacent to
... membrane was investigated by photocrosslinking. Nascent polypeptides of different lengths, each containing a single IgM transmembrane sequence that functions either as a stop-transfer or a signal-anchor sequence, were synthesized by in vitro translation of truncated mRNAs in the presence of N~-(5-az ...
... membrane was investigated by photocrosslinking. Nascent polypeptides of different lengths, each containing a single IgM transmembrane sequence that functions either as a stop-transfer or a signal-anchor sequence, were synthesized by in vitro translation of truncated mRNAs in the presence of N~-(5-az ...
Dynamin as a mover and pincher during cell migration and invasion
... Expression of the GTPase-deficient DynK44A mutant or a Dyn⌬PRD mutant inhibits the formation, growth and speed of these comets. Interestingly, Dyn2 is concentrated at the actin–vesicle-membrane interface but also extends along the length of the comet tails. This suggests a direct structurefunction r ...
... Expression of the GTPase-deficient DynK44A mutant or a Dyn⌬PRD mutant inhibits the formation, growth and speed of these comets. Interestingly, Dyn2 is concentrated at the actin–vesicle-membrane interface but also extends along the length of the comet tails. This suggests a direct structurefunction r ...
Plant Phosphoglycerolipids: The Gatekeepers of Vascular Cell
... In higher plants, the plant vascular system has evolved as an inter-organ communication network essential to deliver a wide range of signaling factors among distantly separated organs. To become conductive elements, phloem and xylem cells undergo a drastic differentiation program that involves the d ...
... In higher plants, the plant vascular system has evolved as an inter-organ communication network essential to deliver a wide range of signaling factors among distantly separated organs. To become conductive elements, phloem and xylem cells undergo a drastic differentiation program that involves the d ...
Expression of the nidogen-binding site of the laminin γ1 chain
... homologous recombination does not result in any gross changes in development, and the basement membranes in these animals appear to be structurally normal. However, it could be shown that the related protein (nidogen-2) was redistributed and/or upregulated in certain tissues in the nidogen-1-null an ...
... homologous recombination does not result in any gross changes in development, and the basement membranes in these animals appear to be structurally normal. However, it could be shown that the related protein (nidogen-2) was redistributed and/or upregulated in certain tissues in the nidogen-1-null an ...
Bovine Peptidoglycan Recognition Protein
... nnate immunity provides the first line of antimicrobial defense in animals (1), and many components of this system are evolutionarily conserved from insects to humans (2). Pattern recognition molecules, encoded in the germ line, are essential components of innate immunity, because they distinguish i ...
... nnate immunity provides the first line of antimicrobial defense in animals (1), and many components of this system are evolutionarily conserved from insects to humans (2). Pattern recognition molecules, encoded in the germ line, are essential components of innate immunity, because they distinguish i ...
Yantar, a conserved arginine-rich protein is involved in Drosophila
... of these mutations (5E24, 5K29, and 3A8) were selected because of their reproducible and fairly penetrant melanotic tumor phenotype, and we named their corresponding genes yantar (ytr), polka dots (pkdt), and splotchy (splo). Hemocytes from these mutants were visualized after immunostaining using tw ...
... of these mutations (5E24, 5K29, and 3A8) were selected because of their reproducible and fairly penetrant melanotic tumor phenotype, and we named their corresponding genes yantar (ytr), polka dots (pkdt), and splotchy (splo). Hemocytes from these mutants were visualized after immunostaining using tw ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.