Cooperative Regulation of Cell Polarity and Growth by Drosophila
... localized protein required for polarization of embryonic and, as demonstrated here, imaginal disc and follicular epithelia. We show that the tumor suppressors lethal giant larvae (lgl) and discs-large (dlg) have identical effects on all three epithelia, and that scrib also acts as a tumor suppressor ...
... localized protein required for polarization of embryonic and, as demonstrated here, imaginal disc and follicular epithelia. We show that the tumor suppressors lethal giant larvae (lgl) and discs-large (dlg) have identical effects on all three epithelia, and that scrib also acts as a tumor suppressor ...
DEFINING THE ROLE OF THE SHP2 PROTEIN TYROSINE
... into mature mucosal or connective tissue mast cells (with specialized granule contents, etc.) in response to factors released by the local tissue5. The two varieties of mast cells are differentiated by their tissue of residence and can be identified by their differential histological staining proper ...
... into mature mucosal or connective tissue mast cells (with specialized granule contents, etc.) in response to factors released by the local tissue5. The two varieties of mast cells are differentiated by their tissue of residence and can be identified by their differential histological staining proper ...
Control of alternative splicing in immune responses: many
... AS events are enriched in genes involved in many aspects of T-cell biology and effector functions (6, 7). Enriched activities include canonical T-cell signaling pathways, such as nuclear factor-jB (NF-jB) and c-Jun N-terminal kinase and mitogen-activated protein kinase signaling, Rho-mediated change ...
... AS events are enriched in genes involved in many aspects of T-cell biology and effector functions (6, 7). Enriched activities include canonical T-cell signaling pathways, such as nuclear factor-jB (NF-jB) and c-Jun N-terminal kinase and mitogen-activated protein kinase signaling, Rho-mediated change ...
The Evolution of SMC Proteins: Phylogenetic Analysis and Structural
... assumption that each of the individual eukaryotic SMC sequences shares the same vertical pattern of inheritance and therefore should follow the same branching order. As these trees using concatenated alignments had bootstrap values of 100% at all nodes (online supplementary figure) and in turn led t ...
... assumption that each of the individual eukaryotic SMC sequences shares the same vertical pattern of inheritance and therefore should follow the same branching order. As these trees using concatenated alignments had bootstrap values of 100% at all nodes (online supplementary figure) and in turn led t ...
Biochemistry of saliva and tooth tissues
... hydroxyapatite), water and organic material initially composed of high amount of protein; during tooth matures proteins are removed and the voids are backfilled with HAP Remineralisation of teeth - repairing damages of the tooth only to a certain degree The maintenance and repair of human tooth enam ...
... hydroxyapatite), water and organic material initially composed of high amount of protein; during tooth matures proteins are removed and the voids are backfilled with HAP Remineralisation of teeth - repairing damages of the tooth only to a certain degree The maintenance and repair of human tooth enam ...
ANISOTROPIC EXPANSION OF THE PLANT CELL WALL
... are three dimensional but methods for observing growth, such as photography, are inherently two dimensional. Furthermore, growth within a volume can be spatially heterogeneous, but usually only the surface is accessible. Thus the velocities at which elements inside the organ move are obscure. Both o ...
... are three dimensional but methods for observing growth, such as photography, are inherently two dimensional. Furthermore, growth within a volume can be spatially heterogeneous, but usually only the surface is accessible. Thus the velocities at which elements inside the organ move are obscure. Both o ...
Print
... Expression and Function of Laminins in the Embryonic and Mature Vasculature. Physiol Rev 85: 979 –1000, 2005; doi:10.1152/physrev.00014.2004.—Endothelial cells of the blood and lymphatic vasculature are polarized cells with luminal surfaces specialized to interact with inflammatory cells upon the ap ...
... Expression and Function of Laminins in the Embryonic and Mature Vasculature. Physiol Rev 85: 979 –1000, 2005; doi:10.1152/physrev.00014.2004.—Endothelial cells of the blood and lymphatic vasculature are polarized cells with luminal surfaces specialized to interact with inflammatory cells upon the ap ...
Determination and Quantification of Molecular Interactions in Protein
... The properties of proteins make them excellent starting materials for films and coatings. Intrinsic properties of the film components and extrinsic processing factors affect the final properties of the film [30]. The amino acid composition of the proteins is one crucial factor for intrinsic properti ...
... The properties of proteins make them excellent starting materials for films and coatings. Intrinsic properties of the film components and extrinsic processing factors affect the final properties of the film [30]. The amino acid composition of the proteins is one crucial factor for intrinsic properti ...
Glucose transporters in the mammalian blood cells
... Glucose is the main source of metabolic energy for various cellular functions, and thus plays a central role in supporting intermediary metabolism and cellular homeostasis. Since plasma membrane is impermeable to glucose, its cellular uptake is mediated by two distinct processes via specific glucose ...
... Glucose is the main source of metabolic energy for various cellular functions, and thus plays a central role in supporting intermediary metabolism and cellular homeostasis. Since plasma membrane is impermeable to glucose, its cellular uptake is mediated by two distinct processes via specific glucose ...
Site directed mutagenesis of Drosophila flightin disrupts
... relies on a pronounced stretch activation response to produce oscillatory work. Recombinant flightin binds to myosin in vitro and to a recombinant fragment of the myosin rod that include the COOH-terminal 600 amino acids (28 amino acid-repeat zone 19 to tailpiece) (Ayer and Vigoreaux 2003). The inte ...
... relies on a pronounced stretch activation response to produce oscillatory work. Recombinant flightin binds to myosin in vitro and to a recombinant fragment of the myosin rod that include the COOH-terminal 600 amino acids (28 amino acid-repeat zone 19 to tailpiece) (Ayer and Vigoreaux 2003). The inte ...
Identification of Genes Involved in the Assembly and Biosynthesis of... N
... List of Figures Figure 1.1: Tree of life for the Bacteria, Archaea and Eukarya domains ........................................ 5 Figure 1.2: Arrangements of flagella on a bacterial cell .................................................................. 7 Figure 1.3: Assembly of the bacterial fla ...
... List of Figures Figure 1.1: Tree of life for the Bacteria, Archaea and Eukarya domains ........................................ 5 Figure 1.2: Arrangements of flagella on a bacterial cell .................................................................. 7 Figure 1.3: Assembly of the bacterial fla ...
XTalkDB: a database of signaling pathway crosstalk
... a well-defined set of regulatory and physical interactions among receptors, intermediate signaling proteins, transcription factors and target genes. The perception of an external signal by receptors causes the activities of intermediate proteins to change and ultimately results in the regulation of ...
... a well-defined set of regulatory and physical interactions among receptors, intermediate signaling proteins, transcription factors and target genes. The perception of an external signal by receptors causes the activities of intermediate proteins to change and ultimately results in the regulation of ...
Article Title Authors Author affiliation Correspondence information
... of nutrition deficiency, cytokines and growth factors decreases and neurotoxic drugs [13-16]. Therefore, a clear understanding of how the MAPK/JNK signal pathway influences autophagy can lead to characterization of the underlying molecular mechanisms. Elucidation of the signaling cascades that the r ...
... of nutrition deficiency, cytokines and growth factors decreases and neurotoxic drugs [13-16]. Therefore, a clear understanding of how the MAPK/JNK signal pathway influences autophagy can lead to characterization of the underlying molecular mechanisms. Elucidation of the signaling cascades that the r ...
Polypeptide Composition of Chlamydia trachomatis
... major polypeptide is the principal outer membrane protein, and the 29000 dalton polypeptide is the type-specific antigen. INTRODUCTION ...
... major polypeptide is the principal outer membrane protein, and the 29000 dalton polypeptide is the type-specific antigen. INTRODUCTION ...
www.iplantcollaborative.org
... • Longer cell cycle • Dependent on protein products • DNA doesn’t matter, proteins do ...
... • Longer cell cycle • Dependent on protein products • DNA doesn’t matter, proteins do ...
Processing Synthesis of Cellulase from Ripening
... Cellulase has been shown to be induced to a high level during ripening of avocado fruit (4, 30). Recent work has demonstrated, using a cellulase cDNA probe, that the increase in cellulase protein results from an increase in cellulase mRNA at the onset of ripening ( 14). Although the induction of cel ...
... Cellulase has been shown to be induced to a high level during ripening of avocado fruit (4, 30). Recent work has demonstrated, using a cellulase cDNA probe, that the increase in cellulase protein results from an increase in cellulase mRNA at the onset of ripening ( 14). Although the induction of cel ...
The Type B Phosphatidylinositol-4-Phosphate 5
... 5-kinases, including amino acid sequences deduced from putative and uncharacterized genes, can be classified into types A and B (Mueller-Roeber and Pical, 2002). The smaller type A enzymes (isoforms 10 and 11) exhibit a domain structure similar to that of animal and human PI4P 5-kinases, whereas typ ...
... 5-kinases, including amino acid sequences deduced from putative and uncharacterized genes, can be classified into types A and B (Mueller-Roeber and Pical, 2002). The smaller type A enzymes (isoforms 10 and 11) exhibit a domain structure similar to that of animal and human PI4P 5-kinases, whereas typ ...
The Early Interaction of the Outer Membrane Protein PhoE with
... cross-linking approach, the latter protein was found to interact with nascent PhoE chains as short as 57 amino acids (1–3). Subsequently, at a late co-translational or early post-translational stage the precursor protein interacts with SecB (4 – 6). This SecB䡠precursor complex is then targeted to Se ...
... cross-linking approach, the latter protein was found to interact with nascent PhoE chains as short as 57 amino acids (1–3). Subsequently, at a late co-translational or early post-translational stage the precursor protein interacts with SecB (4 – 6). This SecB䡠precursor complex is then targeted to Se ...
PDF
... primary mesenchyme cell (PMC) lineage (reviewed by Oliveri et al., 2008; Ettensohn, 2009). The PMC gene network is currently one of the most complete developmental GRNs and is being used to elucidate GRN architecture, the evolution of developmental programs, and developmental plasticity. For example ...
... primary mesenchyme cell (PMC) lineage (reviewed by Oliveri et al., 2008; Ettensohn, 2009). The PMC gene network is currently one of the most complete developmental GRNs and is being used to elucidate GRN architecture, the evolution of developmental programs, and developmental plasticity. For example ...
Non-Targeted and Targeted Protein Movement
... Plant cells rely on plasmodesmata for intercellular transport of small signaling molecules as well as larger informational macromolecules such as proteins. A green fluorescent protein (GFP) reporter and low-pressure microprojectile bombardment were used to quantify the degree of symplastic continuit ...
... Plant cells rely on plasmodesmata for intercellular transport of small signaling molecules as well as larger informational macromolecules such as proteins. A green fluorescent protein (GFP) reporter and low-pressure microprojectile bombardment were used to quantify the degree of symplastic continuit ...
Norton J Nutr 2006
... The effects of leucine are, at least in part, associated with the absence of the branched-chain aminotransferase (BCAT) enzyme in liver (15). Absence of BCAT in liver results in an enriched supply of the three BCAAs channeled to skeletal muscle. Dietary BCAA reach the blood virtually unaltered from ...
... The effects of leucine are, at least in part, associated with the absence of the branched-chain aminotransferase (BCAT) enzyme in liver (15). Absence of BCAT in liver results in an enriched supply of the three BCAAs channeled to skeletal muscle. Dietary BCAA reach the blood virtually unaltered from ...
Author`s personal copy
... In Caenorhabditis elegans the cell cycle is also remodeled but much earlier at the two cell stage. This reflects the fact that zygotic transcription starts at the 4-cell stage and gastrulation begins at the 20-cell stage in C. elegans (Baugh et al., 2003). Interestingly, the mechanism employed in C. ...
... In Caenorhabditis elegans the cell cycle is also remodeled but much earlier at the two cell stage. This reflects the fact that zygotic transcription starts at the 4-cell stage and gastrulation begins at the 20-cell stage in C. elegans (Baugh et al., 2003). Interestingly, the mechanism employed in C. ...
Cellular localization of the potassium channel Kir7.1 in guinea pig
... the partial Kir7.1 gene (KCNJ13), including two thirds of the coding region split by a 2094 bp intron (GenBank accession number AF200714; Fig. 1B). A comparison of guinea pig and human genomic structure revealed that the position and length of the intron are strongly conserved, although sequence con ...
... the partial Kir7.1 gene (KCNJ13), including two thirds of the coding region split by a 2094 bp intron (GenBank accession number AF200714; Fig. 1B). A comparison of guinea pig and human genomic structure revealed that the position and length of the intron are strongly conserved, although sequence con ...
Amyloid-b Acts as a Regulator of Neurotransmitter Release
... Alzheimer’s disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-b peptide (Ab42). However, the underlying molecular and cellular mechanisms behind these deficits are not fully understood. Here we provide evidence of a mechanism by which Ab42 affects synaptic tra ...
... Alzheimer’s disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-b peptide (Ab42). However, the underlying molecular and cellular mechanisms behind these deficits are not fully understood. Here we provide evidence of a mechanism by which Ab42 affects synaptic tra ...
A cap `n` collar protein isoform contains a selective Hox repressor
... The third class of cDNAs from the locus corresponded to cncC transcripts. These cDNAs have identical sequence to the cncB cDNAs, except that exon B1 is absent, and five additional exons (C1-C5) are spliced onto the 5′ end of exon B2. A probe containing the C1-C4 exons detects the 6.6 kb cncC transcr ...
... The third class of cDNAs from the locus corresponded to cncC transcripts. These cDNAs have identical sequence to the cncB cDNAs, except that exon B1 is absent, and five additional exons (C1-C5) are spliced onto the 5′ end of exon B2. A probe containing the C1-C4 exons detects the 6.6 kb cncC transcr ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.