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THERAPEUTIC AGENTS
THERAPEUTIC AGENTS

... Chloride delivery - activate other chloride carriers ...
The Plasma Membrane
The Plasma Membrane

... is responsible for much of the movement of fluids into and out of cells. ...
Synaptic Potentials
Synaptic Potentials

The Connexin46 mutant (V44M)
The Connexin46 mutant (V44M)

CN Theveneau
CN Theveneau

... migration was based on the fact that NC cells were mesenchymal and highly migratory cells facing permissive areas containing extracellular matrix (ECM) and restrictive areas defined by negative cues present in the local environment. Consequently, NC cells would explore their direct surroundings and i ...
research article Numerical study of the electroporation pulse shape
research article Numerical study of the electroporation pulse shape

... world and for this reason it has drawn the attention of many researchers. Chemotherapy has been used for many years and is one of the most common treatments for cancer. Cytotoxic chemotherapeutic drugs are usually hydrophilic with very low transport through the cell membrane and thus high doses of t ...
Rapid analysis of the extracellular matrix protein decorin using the
Rapid analysis of the extracellular matrix protein decorin using the

... is a member of the small leucine-rich family of proteoglycans, which are prominent constituents of both the ECM and the cell surface. Decorin is post-translationally modified by polymerization of a single glycosaminoglycan (GAG) chain onto a site near the N-terminus of the core protein and by N-glyc ...
Identification of Diphtheria Toxin Receptor and a
Identification of Diphtheria Toxin Receptor and a

Session 362 Corneal tissue engineering and molecular
Session 362 Corneal tissue engineering and molecular

... Translational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD. Purpose: Collagen fibrillogenesis can be controlled by pH, temperature, and ionic strength. Using these factors, we have previously developed a type I collagen based ‘vitrigel’ biomaterial with cornea mimetic fibril al ...
The Dictyostelium LvsA Protein is Localized on the Contractile
The Dictyostelium LvsA Protein is Localized on the Contractile

... charge resembled wild-type discharge as the phase lucent vacuoles contracted within 3–4 s (Figure 7C, arrows). In the second type of mutant discharge, vacuoles appeared to fuse suddenly with the surface of the cell and a bleb formed at the same site, suggesting rapid addition of new membrane (Figure ...
Model Questions 1
Model Questions 1

... Adipocytes Melanocytes Lymphocytes Mast cells 6- Name the different types of cartilage and give examples, location and the function of each. There are three types of cartilages: 1- hyaline 2- elastic 3- fibrocartilage ...
Embryonic development of the human hematopoietic system
Embryonic development of the human hematopoietic system

... occasional presence of macrophages and primitive megakaryocytes has been also described (Fukuda, 1973). Although studies on hematopoietic cell emergence at these early stages still remain scarce, our own observations from day 19 of development have suggested that the sequence described in animal emb ...
Role of Cytoskeleton Changes and Expression
Role of Cytoskeleton Changes and Expression

... effected by a single exposure to a low dose of carcinogen that by itself causes no (or few) tumors. In contrast, for tumors to develop from initiated cells, repeated treatment with tumor promoters is necessary, and it has been suggested that, during this time span, initiated cells are induced to giv ...
Zygotic expression of the pebble locus is required for cytokinesis
Zygotic expression of the pebble locus is required for cytokinesis

... growth of membranes from the periphery of the embryo to enclose the nuclei, resulting in the formation of the cellular blastoderm. The 14th mitoses are radically different from all preceding mitoses. They are the first cellular mitoses and they occur asynchronously, groups of cells dividing in a com ...
Angiotensin AT1-Receptors Depolarize Neonatal Spinal
Angiotensin AT1-Receptors Depolarize Neonatal Spinal

... voltage clamp (VH ⫺65 mV), 7/22 motoneurons displayed an ANG-IIinduced tetrodotoxin-resistant inward current (⫺128 ⫾ 31 pA) with a similar time course, an associated reduction in membrane conductance and net current reversal at ⫺98.8 ⫾ 3.9 mV. Losartan-sensitive ANG II responses were also evoked in ...
CL_review-RS - The OBO Foundry
CL_review-RS - The OBO Foundry

... research community to flesh out the hematopoietic cell branch. The end result has been a major improvement in both the content and the structure of this branch. Similar outreach to other relevant communities is encouraged. 9. Tracker for submissions of new terms and errors - yes, through Sourceforge ...
(a) (i) the three features correctly labelled on cheek cell
(a) (i) the three features correctly labelled on cheek cell

... where energy released ecf from leaf cell labelling accept chloroplasts make sugar or glucose accept vacuole contains sap accept if cell wall mis labelled on cheek cell, support or hold ...
Vemurafenib resistance selects for highly
Vemurafenib resistance selects for highly

Fifty Ways to Make a Neuron:* Shifts in Stem Cell Hierarchy and
Fifty Ways to Make a Neuron:* Shifts in Stem Cell Hierarchy and

... signals (86, 87). This model, which would require generation of at least 2 germ layers for neural induction, has been challenged by a recent report of Tropepe et al (88). In their study, they provide evidence for a direct conversion of ES cells into primitive neural stem cells. When plated at low de ...
Tracheary Element Differentiation Uses a Novel Mechanism
Tracheary Element Differentiation Uses a Novel Mechanism

... to identify and distinguish central morphological or molecular PCD events from confounding concurrent developmental events, and no basal PCD machinery has yet been identified in plants analogous to the well-defined caspase pathway for apoptosis in animals (Cohen, 1997). Although the evolutionary rel ...
Characterization of Organelles in the Vacuolar
Characterization of Organelles in the Vacuolar

... We have shown the localization and mobilization of modified green fluorescent proteins (GFPs) with various signals in different compartments in a vacuolar-sorting system of tobacco BY-2 cells. In contrast to the efficient secretion of GFP from the transformed cells expressing SP-GFP composed of a si ...
Mitochondrial inheritance is mediated by microtubules in
Mitochondrial inheritance is mediated by microtubules in

... apoptosis and autophagy. Mitochondria are essential for cell viability and therefore must be accurately inherited during cell division in order to generate viable daughter cells. Therefore, the dividing cell employs partitioning strategies to ensure that each daughter cell inherits equal complements ...
topic #4: angiosperm anatomy and selected aspects
topic #4: angiosperm anatomy and selected aspects

... sap ascent, one that is sufficient to explain this process in tall plants. At another time, I will discuss an auxiliary mechanism operative in some plants at some times. Although the cohesion theory has come under attack periodically,8 supporters rally and provide counterbalancing evidence.) An unde ...
- Wiley Online Library
- Wiley Online Library

Presence of exposed phospholipids in the outer membrane of Vibrio
Presence of exposed phospholipids in the outer membrane of Vibrio

... Membrane preparation. Isolation of crude cell envelope and its fractionation into outer and inner membrane with 4wurea for the analysis of phospholipids and LPS, and with 1% Sarkosyl for the assay of membrane proteins, were carried out as described previously (Lohia et al., 1984, 1985; Filip et al., ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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