Cdk1 regulates centrosome separation by restraining proteolysis of
... yet fail to assemble a spindle (Lim et al, 1996). Hence, failure to separate SPBs is specifically due to the inability to dephosphorylate Tyrosine 19. cdc28-as1 allele carries an F88G substitution that alters the ATP-binding pocket and confers sensitivity to a bulky ATP analog, 1NM-PP1 (Bishop et al, ...
... yet fail to assemble a spindle (Lim et al, 1996). Hence, failure to separate SPBs is specifically due to the inability to dephosphorylate Tyrosine 19. cdc28-as1 allele carries an F88G substitution that alters the ATP-binding pocket and confers sensitivity to a bulky ATP analog, 1NM-PP1 (Bishop et al, ...
PDF
... anterior blast cell clones. This interdigitation is most pronounced for the m blast cell clones, whose definitive progeny span 3 segments in the mid-body of the animal (Weisblat and Shankland, 1985). Does the embryo compensate for the lack of the normal mesodermal complement in the anteriormost segme ...
... anterior blast cell clones. This interdigitation is most pronounced for the m blast cell clones, whose definitive progeny span 3 segments in the mid-body of the animal (Weisblat and Shankland, 1985). Does the embryo compensate for the lack of the normal mesodermal complement in the anteriormost segme ...
Role of plectin in cytoskeleton organization and dynamics
... conspicuous accumulation at focal contacts of cultured cells and its colocalization with their actin stress fibers, most noticeable in cells at stationary phase, strongly supported this view. The partial colocalization of plectin, microfilaments and intermediate filaments, as revealed in these studi ...
... conspicuous accumulation at focal contacts of cultured cells and its colocalization with their actin stress fibers, most noticeable in cells at stationary phase, strongly supported this view. The partial colocalization of plectin, microfilaments and intermediate filaments, as revealed in these studi ...
Lecture 19. secondary phloem-2
... • It is a complex tissue which contains Sieve Elements. – Sieve Cells (SC) are characteristic for Gymnosperms, – while Angiosperms produce Sieve Tube Members (STM). (STM). The latter form Sieve Tubes when joined end to end. • Sieve Tube Members have Sieve Plates on their end walls. These contain con ...
... • It is a complex tissue which contains Sieve Elements. – Sieve Cells (SC) are characteristic for Gymnosperms, – while Angiosperms produce Sieve Tube Members (STM). (STM). The latter form Sieve Tubes when joined end to end. • Sieve Tube Members have Sieve Plates on their end walls. These contain con ...
Transfected Connexin45 Alters Gap Junction Permeability in Cells
... between cells. Gap junction channels allow the passage of ions and small aqueous molecules from the cytoplasm of one cell to another (for reviews see references 2, 13, 31). A functional gap junction channel consists of two plasma membrane hemichannels, one in each cell, composed of hexamers of trans ...
... between cells. Gap junction channels allow the passage of ions and small aqueous molecules from the cytoplasm of one cell to another (for reviews see references 2, 13, 31). A functional gap junction channel consists of two plasma membrane hemichannels, one in each cell, composed of hexamers of trans ...
Modeling Pharmacology in Cardiac Myocytes
... patients on a routine basis. These results serve as a proof of concept that side effects as well as therapeutic outcomes can be predicted from models of normal cardiac electrophysiology. Unfortunately as was demonstrated with the Nobel ventricular myocyte, models do not need to be accurate to mimic ...
... patients on a routine basis. These results serve as a proof of concept that side effects as well as therapeutic outcomes can be predicted from models of normal cardiac electrophysiology. Unfortunately as was demonstrated with the Nobel ventricular myocyte, models do not need to be accurate to mimic ...
Associative learning increases adult neurogenesis during a critical
... GA, USA) in physiological saline solution. BrdU can be incorporated into replicating DNA in the S phase of the cell cycle and thereby marks cells that are actively proliferating. BrdU is available in the brain for a period of approximately 2 h after a systemic injection (Cameron & McKay, 2001). Grou ...
... GA, USA) in physiological saline solution. BrdU can be incorporated into replicating DNA in the S phase of the cell cycle and thereby marks cells that are actively proliferating. BrdU is available in the brain for a period of approximately 2 h after a systemic injection (Cameron & McKay, 2001). Grou ...
Studies of vacuolar trafficking pathways regulated by RAB5 and
... daughter cells in mutant roots further divided periclinally (Figure 4). These results indicate that VPS9a is required to repress middle cortex formation at the premature stage in root development. It has been shown that middle cortex formation is under regulation of a plant hormone, gibberellin (Paq ...
... daughter cells in mutant roots further divided periclinally (Figure 4). These results indicate that VPS9a is required to repress middle cortex formation at the premature stage in root development. It has been shown that middle cortex formation is under regulation of a plant hormone, gibberellin (Paq ...
Cytoskeletal control of plant cell shape: getting the fine points
... conical shapes of petal epidermal cells affect their optical properties so as to enhance coloration. The shapes of plant cells are de®ned by their walls, and are acquired during development according to the patterns in which walls expand during organ and cell growth. Cell expansion depends on the ab ...
... conical shapes of petal epidermal cells affect their optical properties so as to enhance coloration. The shapes of plant cells are de®ned by their walls, and are acquired during development according to the patterns in which walls expand during organ and cell growth. Cell expansion depends on the ab ...
Impedance technology reveals correlations between cytotoxicity and
... The study of drug-like or absorption, distribution, metabolism, excretion and toxicity (ADMET) properties of new chemicals early in drug discovery has gained significant importance over the last decade due to the high rate of late drug failures during clinical trials (Hamid et al, 2004), in addition ...
... The study of drug-like or absorption, distribution, metabolism, excretion and toxicity (ADMET) properties of new chemicals early in drug discovery has gained significant importance over the last decade due to the high rate of late drug failures during clinical trials (Hamid et al, 2004), in addition ...
LESSON—19 THE EXTERIOR OP THE CELL. A. Objectives
... Examples of molecules to which cell surface receptors respond include all of the following EXCEPT A. ...
... Examples of molecules to which cell surface receptors respond include all of the following EXCEPT A. ...
Synthesis of a Callosic Substance during Rhizoid Differentiation in
... with rhizoid differentiation was eliminated by observation of unstained rhizoids. Blue autofluorescence was not observed in unstained cells (data not shown). In general, a rhizoid forms only from the terminal cell, suggesting that the terminal cell recognizes its own position in the filament. Upon c ...
... with rhizoid differentiation was eliminated by observation of unstained rhizoids. Blue autofluorescence was not observed in unstained cells (data not shown). In general, a rhizoid forms only from the terminal cell, suggesting that the terminal cell recognizes its own position in the filament. Upon c ...
Cell Cycle Regulation of the Activity and Subcellular Localization of
... phenylmethylsulfonyl phosphate, 1 p,g/ml each of soybean trypsin inhibitor, leupeptin and pepstatin, and 30 ~g/ml of DNase I and RNase A. Subsequently, samples were passed five times through a 27-gauge needle and centrifuged for 5 min at 10,000 g (4°C). Supernatants were stored at - 8 0 ° C until us ...
... phenylmethylsulfonyl phosphate, 1 p,g/ml each of soybean trypsin inhibitor, leupeptin and pepstatin, and 30 ~g/ml of DNase I and RNase A. Subsequently, samples were passed five times through a 27-gauge needle and centrifuged for 5 min at 10,000 g (4°C). Supernatants were stored at - 8 0 ° C until us ...
Full Text - The International Journal of Developmental Biology
... the way, was well aware of the shaky ground he was treading, but he felt a strong anti-teleological urge and saw his speculations justified by their heuristic value. In his words, they offer "the advantage that one can form certain ideas on organismic processes. which is always necessary if one want ...
... the way, was well aware of the shaky ground he was treading, but he felt a strong anti-teleological urge and saw his speculations justified by their heuristic value. In his words, they offer "the advantage that one can form certain ideas on organismic processes. which is always necessary if one want ...
Possible new intranuclear symbionts of Paramecium caudatum
... of Proteobacteria. For well studied Enterobacteria (belonging to g-Proteobacteria) it was shown that the ability to penetrate host cell and thus become intracellular pathogen depends on a set of genes which are incorporated into the genome as a single block. These blocks were named “pathogenicity is ...
... of Proteobacteria. For well studied Enterobacteria (belonging to g-Proteobacteria) it was shown that the ability to penetrate host cell and thus become intracellular pathogen depends on a set of genes which are incorporated into the genome as a single block. These blocks were named “pathogenicity is ...
Capecchi - Nobel Lecture
... additional short viral DNA sequence(3). It seemed plausible to me that highly evolved viral genomes which, as part of their life cycle, resided in the host cell genome, might contain bits of DNA sequence that enhanced their ability to establish themselves within the host cell genome. I searched the ...
... additional short viral DNA sequence(3). It seemed plausible to me that highly evolved viral genomes which, as part of their life cycle, resided in the host cell genome, might contain bits of DNA sequence that enhanced their ability to establish themselves within the host cell genome. I searched the ...
Apoptosis induced by prolonged exposure to odorants in cultured
... neurons. Thus, our in vitro data provide good evidence that olfactory EC can be induced to undergo apoptosis by prolonged and continuous odorant exposure. Given the fact that LY83583 can decrease the odorant-, but not the campotheticin-induced apoptosis, our results can only be explained if an impor ...
... neurons. Thus, our in vitro data provide good evidence that olfactory EC can be induced to undergo apoptosis by prolonged and continuous odorant exposure. Given the fact that LY83583 can decrease the odorant-, but not the campotheticin-induced apoptosis, our results can only be explained if an impor ...
Differential roles for the low-affinity phosphate transporters Pho87
... the repression of the stress-responsive genes (Supplementary Figure S1A at http://www.BiochemJ.org/bj/434/bj4340243add.htm). Consequently, we observed that the pho84Δ and the pho4Δ pho87Δ mutants displayed retardation in growth resumption after addition of phosphate to Pi -starved cells when compare ...
... the repression of the stress-responsive genes (Supplementary Figure S1A at http://www.BiochemJ.org/bj/434/bj4340243add.htm). Consequently, we observed that the pho84Δ and the pho4Δ pho87Δ mutants displayed retardation in growth resumption after addition of phosphate to Pi -starved cells when compare ...
SC-Biology South Carolina Academic Standards 2005
... Evaluate a technological design or product on the basis of designated criteria (including cost, time, and materials). Compare the processes of scientific investigation and technological design. Lab: Measurement Lab: Diffusion Across a Semi-permeable Membrane Lab: Mouse Genetics (One Trait) Lab: Natu ...
... Evaluate a technological design or product on the basis of designated criteria (including cost, time, and materials). Compare the processes of scientific investigation and technological design. Lab: Measurement Lab: Diffusion Across a Semi-permeable Membrane Lab: Mouse Genetics (One Trait) Lab: Natu ...
8879.full - The Journal of Neuroscience
... blockade of this miRNA by antisense oligonucleotides only resulted in subtle phenotypes, with mild delays in differentiation and no detectable malformation (Cao et al., 2007; Visvanathan et al., 2007; Cheng et al., 2009). Based on these findings, it was concluded, that miR-124 regulates proliferatio ...
... blockade of this miRNA by antisense oligonucleotides only resulted in subtle phenotypes, with mild delays in differentiation and no detectable malformation (Cao et al., 2007; Visvanathan et al., 2007; Cheng et al., 2009). Based on these findings, it was concluded, that miR-124 regulates proliferatio ...
as a PDF
... responses to the envelope glycoprotein B (gB), which is a component of glycoprotein complex gcI (Gretch et al., 1988; Kari et al., 1990). Our laboratory and others have derived murine monoclonal antibodies (MAbs) which react with either the N-terminal gp93 subunit or the Cterminal gp55 subunit of gB ...
... responses to the envelope glycoprotein B (gB), which is a component of glycoprotein complex gcI (Gretch et al., 1988; Kari et al., 1990). Our laboratory and others have derived murine monoclonal antibodies (MAbs) which react with either the N-terminal gp93 subunit or the Cterminal gp55 subunit of gB ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.