
In vitro study of chorionic and ectoplacental
... origin has been assigned to the syncytial layer, which would then arise from the Langhans cells (Carter, 1964; Enders, 19656; Kemnitz, 1970). Midgley, Pierce, Deneau & Gosling (1963), Tao & Hertig (1965) and Gerbie, Hathaway & Brewer (1968), using [3Hlthymidine as a cell tracer, have obtained data i ...
... origin has been assigned to the syncytial layer, which would then arise from the Langhans cells (Carter, 1964; Enders, 19656; Kemnitz, 1970). Midgley, Pierce, Deneau & Gosling (1963), Tao & Hertig (1965) and Gerbie, Hathaway & Brewer (1968), using [3Hlthymidine as a cell tracer, have obtained data i ...
interaction between tumor and immune system: the role of tumor cell
... signals received from tumor cells. The role of DNAМ1 and CD155 interaction for lysis of metastazing cells is determined by the activation of perforin system. Receptors of killer cells, for example, NK, often vary by recognition of different ligands, while tumor cells significantly vary by ligand exp ...
... signals received from tumor cells. The role of DNAМ1 and CD155 interaction for lysis of metastazing cells is determined by the activation of perforin system. Receptors of killer cells, for example, NK, often vary by recognition of different ligands, while tumor cells significantly vary by ligand exp ...
NutriStem hESC XF Serum
... Storage & Handling Precautions and Disclaimer: For in vitro research use only. The product should be stored at -20°C. The product should not be left in the light for prolonged periods as it is light-sensitive. When stored in the dark under ideal conditions, the product is stable until the expiry dat ...
... Storage & Handling Precautions and Disclaimer: For in vitro research use only. The product should be stored at -20°C. The product should not be left in the light for prolonged periods as it is light-sensitive. When stored in the dark under ideal conditions, the product is stable until the expiry dat ...
Non-Flagellar Swimming in Marine Synechococcus
... membrane and create thrust such that the cell moves in the direction of the wave. The observed rotation of the cell body during swimming can be explained by waves that are not axially symmetric. Although there is yet no experimental evidence for this model, aspects of it are certainly testable. Thes ...
... membrane and create thrust such that the cell moves in the direction of the wave. The observed rotation of the cell body during swimming can be explained by waves that are not axially symmetric. Although there is yet no experimental evidence for this model, aspects of it are certainly testable. Thes ...
Cajal 88 Trends
... other authors, such as Schiefferdecker, had not seen nuclei, and had referred to such formations as 'kernlose concentrische Zellen' ('anucleate concentric cells'). Cajal actually admitted that fusiform formations without a clear appearance of a cell body were sometimes seen, but he concluded that th ...
... other authors, such as Schiefferdecker, had not seen nuclei, and had referred to such formations as 'kernlose concentrische Zellen' ('anucleate concentric cells'). Cajal actually admitted that fusiform formations without a clear appearance of a cell body were sometimes seen, but he concluded that th ...
Pods and Nods: a new look at symbiotic nitrogen fixing
... rhizobial strains are analysed by standard taxonomic criteria based on gene sequence comparisons, it is clear that these bacteria do not form part of a homogeneous evolutionary clade. The Rhizobiaceae as a distinct taxonomic group does not exist (Spaink et al., 1998). The clear implication is that n ...
... rhizobial strains are analysed by standard taxonomic criteria based on gene sequence comparisons, it is clear that these bacteria do not form part of a homogeneous evolutionary clade. The Rhizobiaceae as a distinct taxonomic group does not exist (Spaink et al., 1998). The clear implication is that n ...
Regulation of Transcription in Eukaryotes
... while the other helices lie across the complex to stabilize the interaction. In eukaryotic cells, helix-turnhelix proteins include the homeodomain proteins, which play critical roles in the regulation of gene expression during embryonic development. The genes encoding these proteins were first disc ...
... while the other helices lie across the complex to stabilize the interaction. In eukaryotic cells, helix-turnhelix proteins include the homeodomain proteins, which play critical roles in the regulation of gene expression during embryonic development. The genes encoding these proteins were first disc ...
Primary cilia and polycystic kidney disease
... would ensue which would be amplified through Ca2+-induced Ca2+ release via ryanodine receptors. The changes in intracellular Ca2+ concentrations may modulate various cellular functions such as gene expression, growth, differentiation and apoptosis. Loss or dysfunction of polycystin-1 and polycystin- ...
... would ensue which would be amplified through Ca2+-induced Ca2+ release via ryanodine receptors. The changes in intracellular Ca2+ concentrations may modulate various cellular functions such as gene expression, growth, differentiation and apoptosis. Loss or dysfunction of polycystin-1 and polycystin- ...
Origin of Cancer: An Information, Energy, and Matter Disease
... can irreversibly disturb molecular mechanisms, leading to increased local entropy of cellular functions and structures. In terms of physics, changes to these normally highly ordered reaction probabilities lead to a state that is irreversibly biologically imbalanced, but that is thermodynamically mor ...
... can irreversibly disturb molecular mechanisms, leading to increased local entropy of cellular functions and structures. In terms of physics, changes to these normally highly ordered reaction probabilities lead to a state that is irreversibly biologically imbalanced, but that is thermodynamically mor ...
Preview for 2/6/02 – Dr
... Three shapes are especially common among bacteria – spheres, rods and spirals Most are unicellular, some aggregate transiently, some form permanent aggregations of identical cells;some show division of labor between two or more specialized cell times ...
... Three shapes are especially common among bacteria – spheres, rods and spirals Most are unicellular, some aggregate transiently, some form permanent aggregations of identical cells;some show division of labor between two or more specialized cell times ...
BLM 2-30, Compare the Events of Meiosis and Mitosis Key Meiosis I
... the centromere pulls apart, and the sister chromatids separate and are pulled to opposite poles by the spindle ...
... the centromere pulls apart, and the sister chromatids separate and are pulled to opposite poles by the spindle ...
1 Breast Cancer Cell Line Development and Authentication
... 2.1 Establishment of the HeLa cell line and cell line production Indoubtedly, the most important factor to change biomedical research and our understanding of disease at the cellular and molecular levels was the establishment of the first continuously growing human cell line, the HeLa cell (Gey et a ...
... 2.1 Establishment of the HeLa cell line and cell line production Indoubtedly, the most important factor to change biomedical research and our understanding of disease at the cellular and molecular levels was the establishment of the first continuously growing human cell line, the HeLa cell (Gey et a ...
A Piscine Birnavirus Induces Inhibition of Protein Synthesis in CHSE
... Cells employ inhibition of protein synthesis as a defensive mechanism in response to virus invasion, the aim being to limit the production of virus progeny and consequently arrest the spread within the organism. In higher vertebrates, there are mainly three well-known mechanisms by which inhibition ...
... Cells employ inhibition of protein synthesis as a defensive mechanism in response to virus invasion, the aim being to limit the production of virus progeny and consequently arrest the spread within the organism. In higher vertebrates, there are mainly three well-known mechanisms by which inhibition ...
Clear Cell Tumors of the Head and Neck: An
... The rich glycogen content of the cytoplasm gives a clear cell appearance in remnants of dental lamina,4 rests of malassez 5 and eccrine sweat glands. 6 Neutral polysaccharide-glycogen is negatively charged and does not take up the stain with eosin which is also negatively charged hence giving a clea ...
... The rich glycogen content of the cytoplasm gives a clear cell appearance in remnants of dental lamina,4 rests of malassez 5 and eccrine sweat glands. 6 Neutral polysaccharide-glycogen is negatively charged and does not take up the stain with eosin which is also negatively charged hence giving a clea ...
Female Gametophyte Development in Flowering Plants
... AGOs in Drosophila. This implies that MEL1 is required for female germline development, most likely by regulating cell division of pre-meiotic germline cells, modification of meiotic chromosomes, and progression of meiosis; but it does not affect the initiation, establishment, and early mitotic divis ...
... AGOs in Drosophila. This implies that MEL1 is required for female germline development, most likely by regulating cell division of pre-meiotic germline cells, modification of meiotic chromosomes, and progression of meiosis; but it does not affect the initiation, establishment, and early mitotic divis ...
Summer 2012
... Lucia™. QUANTI-Luc™ contains coelenterazine with stabilizing agents that limits substrate auto-oxidation and allows for the reconstituted reagent to be stored. When used in combination with Lucia™, the bioluminescent flash signal generated is longer-lasting, providing flexibility for taking readings ...
... Lucia™. QUANTI-Luc™ contains coelenterazine with stabilizing agents that limits substrate auto-oxidation and allows for the reconstituted reagent to be stored. When used in combination with Lucia™, the bioluminescent flash signal generated is longer-lasting, providing flexibility for taking readings ...
pulsatile shear stress and high glucose concentrations induced
... mitochondrion during oxidative phosphorylation, which involves the electron transport chain. In the chain, electrons are passed through several proteins by different oxidation–reduction reactions. However, a small percentage of the electrons are leaked out from the mitochondrion electron transport c ...
... mitochondrion during oxidative phosphorylation, which involves the electron transport chain. In the chain, electrons are passed through several proteins by different oxidation–reduction reactions. However, a small percentage of the electrons are leaked out from the mitochondrion electron transport c ...
Molecular identification of 26 syntaxin genes and
... frames are interrupted by one to seven short introns, which all display the characteristics of Paramecium introns, i.e. bordering by 50 -GT and AG-30 and a size of 20–31 nucleotides (28,29). However, two genes, Ptsyx6-2 and Ptsyx13-1, appear to be pseudogenes because, if translated, both would produ ...
... frames are interrupted by one to seven short introns, which all display the characteristics of Paramecium introns, i.e. bordering by 50 -GT and AG-30 and a size of 20–31 nucleotides (28,29). However, two genes, Ptsyx6-2 and Ptsyx13-1, appear to be pseudogenes because, if translated, both would produ ...
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies
... cells. In both studies, the implicated gene sets were highly enriched for developmental transcription factors (TFs), many of which become de-repressed upon ES cell differentiation or in a PRC2deficient background. Concurrent studies of histone methylation in ES cells led to the unexpected finding th ...
... cells. In both studies, the implicated gene sets were highly enriched for developmental transcription factors (TFs), many of which become de-repressed upon ES cell differentiation or in a PRC2deficient background. Concurrent studies of histone methylation in ES cells led to the unexpected finding th ...
Cell Surface Membrane Remodelling and Mitochondrial
... To reduce complications associated with cell overlap, PC12 cells and primary neurons are plated at low density (5×104 cells/ 35 mm dish). Undifferentiated PC12 cells are treated with NGF for 4-6 days to induce differentiation or can be are differentiated in tissue culture flasks for up to 10 days pr ...
... To reduce complications associated with cell overlap, PC12 cells and primary neurons are plated at low density (5×104 cells/ 35 mm dish). Undifferentiated PC12 cells are treated with NGF for 4-6 days to induce differentiation or can be are differentiated in tissue culture flasks for up to 10 days pr ...
Mathematical models of radiation action on living cells: From the
... analyzed the data and all these authors proposed the basis of the so-called quantum radiobiology: “to destroy a bacillus it is necessary that its sensitive zone absorbs a minimal number s of quantas” (Curie, 1929). From all these pioneering applications of the target theory, three important comments ...
... analyzed the data and all these authors proposed the basis of the so-called quantum radiobiology: “to destroy a bacillus it is necessary that its sensitive zone absorbs a minimal number s of quantas” (Curie, 1929). From all these pioneering applications of the target theory, three important comments ...
PDF
... B). The brushin-positive cells appeared to be primitive endoderm cells. In order to confirm that brushin is expressed in primitive endoderm cells, the following experiments were performed. ICMs were immunosurgically isolated from late blastocysts, and were cultured for 1 day. After culture, a monola ...
... B). The brushin-positive cells appeared to be primitive endoderm cells. In order to confirm that brushin is expressed in primitive endoderm cells, the following experiments were performed. ICMs were immunosurgically isolated from late blastocysts, and were cultured for 1 day. After culture, a monola ...
Minireview: Global Regulation and Dynamics of Ribonucleic Acid
... Gene expression starts with transcription and is followed by multiple posttranscriptional processes that carry out the splicing, capping, polyadenylation, and export of each mRNA. Interest in posttranscriptional regulation has increased recently with explosive discoveries of large numbers of noncodi ...
... Gene expression starts with transcription and is followed by multiple posttranscriptional processes that carry out the splicing, capping, polyadenylation, and export of each mRNA. Interest in posttranscriptional regulation has increased recently with explosive discoveries of large numbers of noncodi ...
mechanotransduction in lymphatic endothelial cells
... FAK phosphorylation is a critical event also in stretching of cells (29,30). It induces the activation of ERK1/2 and p38 suggesting that mechanotransduction occurs at focal adhesions. Traditionally mechanotransduction differs from other types of signal transduction in that it is thought to occur ind ...
... FAK phosphorylation is a critical event also in stretching of cells (29,30). It induces the activation of ERK1/2 and p38 suggesting that mechanotransduction occurs at focal adhesions. Traditionally mechanotransduction differs from other types of signal transduction in that it is thought to occur ind ...
Document
... Answer ALL 50 questions by marking your answers on your scantron. Take your time and understand each question before you answer. Good Luck! Please keep this document when finished. Just return your scantron to me. As you leave I will check to see that you are enrolled in this class. To save on paper ...
... Answer ALL 50 questions by marking your answers on your scantron. Take your time and understand each question before you answer. Good Luck! Please keep this document when finished. Just return your scantron to me. As you leave I will check to see that you are enrolled in this class. To save on paper ...
Cellular differentiation

In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.