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RNA Interference of Signal Peptide-binding Protein SRP54 Elicits
RNA Interference of Signal Peptide-binding Protein SRP54 Elicits

... and Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8022 ...
Developing a `thick skin`: a paradoxical role for
Developing a `thick skin`: a paradoxical role for

... the root epidermis plays a very different mechanical role than the shoot epidermis. The developmental ontogeny of root epidermal cells is also rather different to that of shoot epidermal cells, and their function in absorbing water and nutrients, notably through specific epidermal structures called ...
Solubilization and Analysis of Mannoprotein Molecules from The
Solubilization and Analysis of Mannoprotein Molecules from The

... Bartnicki-Garcia & Lippman, 1972), but the contribution of some wall material seems to be continuous as time progresses at any region of the mycelium, thus resulting in increased thickness and higher stratification of walls in older regions of hyphae than at the zones near the apex (Trinci & Cooling ...
The centrosome orientation checkpoint is germline stem cell specific
The centrosome orientation checkpoint is germline stem cell specific

... divisions to generate distinct cellular lineages is achieved by stereotypical spindle orientation, some of which are mediated by the programmed rotation of spindles (Goldstein, 2000; Sawa, 2012). In these examples, it is predicted that cell division without the establishment of correct orientation w ...
A Dictyostelium mutant with defective aggregate size
A Dictyostelium mutant with defective aggregate size

... However, factors other than phosphodiesterase must be involved in aggregate size regulation, since some mutants with increased numbers of small fruiting bodies have normal phosphodiesterase and phosphodiesterase inhibitor levels (Riedel et al., 1973). Hohl and Raper (1964) examined several small-agg ...
SASEC2015 Third Southern African Solar Energy Conference 11 – 13 May 2015
SASEC2015 Third Southern African Solar Energy Conference 11 – 13 May 2015

... manufacturing process so their presence in only module 5 points to a different manufacturing batch, supported by the slightly different appearance of module 5 in the EL image. There are also micro-cracks that contribute to lower current. As the micro-cracks and poorly contacted cell occur in the sam ...
Commentary in EMBO Journal
Commentary in EMBO Journal

... waste items from which useful materials can be recovered and reused. Cells engage in analogous activities, and autophagy is an integral part of the larger waste recycling strategy. Autophagy, the process of cellular “self-digestion”, was initially described by Christian de Duve, was outlined in mole ...
Annotation Extension (col 16)
Annotation Extension (col 16)

... 3. Use of has_input or in_presence_of to specify the chemical in the BP response_to_chemical’ 4. What relationship to use to specify the gene which is a target of a transcription factor? 5. Would more relationships in this area be useful? ...
PDF
PDF

... suggesting that the axis of the asymmetric cell division of P3 is determined by extracellular signals from endodermal precursors. In the absence of an E cell, the C daughter cell may have a marginal ability to affect the axis of the P3 division. Next, to reveal whether contact with endodermal precur ...
Human Systems and Homeostasis
Human Systems and Homeostasis

... from other neurons. Humans, like almost all multicellular organisms, are collections of specialized cells that work together. These cells arise from a single cell, the zygote, which is formed by the union of an egg and sperm. The zygote divides and differentiates into more than 200 different types ...
Cell cycle progression in response to oxygen levels | SpringerLink
Cell cycle progression in response to oxygen levels | SpringerLink

... but p53 independent. In addition, loss of HIF1α leads to progression of cells into S phase and a loss of the induction of p21 and p27 [65]. In this way, it is proposed that the expression of p27 is dependent on HIF1α. Conversely, additional studies have shown that p27 is regulated independent of HIF ...
The Plant Extracellular Matrix: News from the Cell`s
The Plant Extracellular Matrix: News from the Cell`s

... 1996), are also being sought. Candace Haiger (Texas Tech University) and Delmer's group showed recently that sucrose synthase (SuSy) is associated with the plasma membrane and may supply UDP-Glc directly to cellulose synthase (Amor et al., 1995). They have been examining immunolabeling patterns of m ...
Tissue-specific Distribution and Dynamic Changes of 5
Tissue-specific Distribution and Dynamic Changes of 5

Akt blocks ligand binding and protects against expanded
Akt blocks ligand binding and protects against expanded

... (S792) of the AR, which conform to the Akt consensus site (RXRXXS/T ), shows that the two serines are conserved in mammals, with the exception of S215 in Canis familiaris. (B) Cos1 cells were transfected with pCMV-AR65Q or pCMV-AR65Q with alanine substitutions at S215 and S792. Phosphorylation of S ...
Cotyledon cells of Vigna mungo seedlings use at least two distinct
Cotyledon cells of Vigna mungo seedlings use at least two distinct

... Ultrastructural analyses of the cotyledon cells of normally germinated V. mungo seeds were conducted to observe how SG interacts with vacuoles to be degraded by -amylase. A cotyledon of a day 3 seedling is composed of heterologous cells with respect to the amount of reserves in the cells. Cells pos ...
The NK2.1 receptor is encoded by Ly-49C and its
The NK2.1 receptor is encoded by Ly-49C and its

... and Fab fragments increased lysis of NK susceptible target cells by resting or IL-2-activated cells (27). These results are thus consistent with NK2.1 being a relevant activation receptor for natural killing. Similar to Ly-49 receptors characterized thus far, NK2.1 is expressed by a subpopulation ra ...
Tomato LeAGP-1 is a plasma membrane-bound
Tomato LeAGP-1 is a plasma membrane-bound

... Arabinogalactan-proteins (AGPs) are a class of highly glycosylated, hydroxyproline-rich glycoproteins that function in plant growth and development. Tomato LeAGP-1 represents a major AGP expressed in cultured cells and plants. Based on cDNA and amino acid sequence analyses along with carbohydrate an ...
Secondary Antibody Responses Immune Complex
Secondary Antibody Responses Immune Complex

... these cells are not numerous enough to account for the observed population. One possible explanation for this population is that some or all of these non-germinal center-derived cells are naive B cells that have been activated only upon secondary Ag exposure. If this were true (i.e., that a large po ...
here - ScienceA2Z.com
here - ScienceA2Z.com

... Genetic material Two different kinds of genetic material exist: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Most organisms use DNA for their long-term information storage, but some viruses (e.g., retroviruses) have RNA as their genetic material. The biological information contained in an ...
Future research leaders
Future research leaders

... mass spectrometry to develop a framework that can be used to locate the mechanism of any disease. In his method, called kinetic metabolomics, small molecules are extracted from a cell culture sample, creating what Dr Nord­ ström refers to as a “molecular soup”. By adding a marking agent to the soup ...
Gastrulation in the sea anemone Nematostella
Gastrulation in the sea anemone Nematostella

... Abstract The sea anemone Nematostella vectensis has recently been established as a new model system for the understanding of the evolution of developmental processes. In particular, the evolutionary origin of gastrulation and its molecular regulation are the subject of intense investigation. However ...
Structure, expression and chromosomal localization of human p80
Structure, expression and chromosomal localization of human p80

... CBs recognize an 80-kD nuclear protein highly enriched in CBs, and this protein has been named p80-coilin. CBs are known to assemble and disassemble during the cell cycle, with the highest number of CBs occurring at mid to late G 1 where p80-coilin is assembled into several small nuclear body-like s ...
Cotyledon cells of Vigna mungo seedlings use at
Cotyledon cells of Vigna mungo seedlings use at

... were intact (Fig. 4 B). The electron density of the PSV became low when the degradation of proteins started (Fig. 4 C). In the same cells, a membranous structure surrounding SGs was observed, and some regions with low electron density (LED) were found (Fig. 4 C). The LED area around the SG was enlar ...
Hyndman, I. (2016) Review: the contribution of both
Hyndman, I. (2016) Review: the contribution of both

... carcinogenesis are less well described; however, there are certain environmental factors which are likely to play a role throughout tumour development and progression. Until recently, the role of environmental agents in epigenetic change was unknown (it was thought that these agents acted exclusive ...
intracellular accumulations
intracellular accumulations

... Most common site: the liver and the heart. With increasing accumulation, the organ enlarges and becomes progressively yellow, soft, and greasy. ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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