Microtechnologies for Cell Microenvironment Control and
... The term “cell microenvironment” involves those factors that directly or indirectly affect cell behavior, by biophysical, biochemical or other pathways. As previously stated, those factors can be classified in: ECM, cells surrounding a single cell, soluble factors, topography or physical properties ...
... The term “cell microenvironment” involves those factors that directly or indirectly affect cell behavior, by biophysical, biochemical or other pathways. As previously stated, those factors can be classified in: ECM, cells surrounding a single cell, soluble factors, topography or physical properties ...
Lamin proteins form an internal nucleoskeleton as well as a
... sibility can be increased by removing chromatin. Knobs and nodes on an internal skeleton can then be immunolabelled using fluorescein- or gold-conjugated anti-lamin A antibodies. These results suggest that the lamins are misnamed as they are also found internally. ...
... sibility can be increased by removing chromatin. Knobs and nodes on an internal skeleton can then be immunolabelled using fluorescein- or gold-conjugated anti-lamin A antibodies. These results suggest that the lamins are misnamed as they are also found internally. ...
Direct interaction of two polarity complexes implicated in epithelial
... result in the mis-localization of PALS1. In summary, our results identify an unexpected direct interaction between PALS1 and Par6 that links two protein complexes important for epithelial cell polarity. Crb is localized to the apical surface of mammalian and fly epithelia and colocalizes at the tigh ...
... result in the mis-localization of PALS1. In summary, our results identify an unexpected direct interaction between PALS1 and Par6 that links two protein complexes important for epithelial cell polarity. Crb is localized to the apical surface of mammalian and fly epithelia and colocalizes at the tigh ...
Apoptosis induced by prolonged exposure to odorants in cultured
... Fig. 4 – Single-cell [Ca2+]i measurements on Fluo-3 loaded olfactory EC continuously exposed to odorants for 3 h. (A) No odorant addition (control), (B) vehicle, (C) ethyl vanillin (EV), (D) LY83583 + ethyl vanillin, (E) isobutyrate (Isob), (F) LY83583 + Isob, (G) camptothecin (positive control). Co ...
... Fig. 4 – Single-cell [Ca2+]i measurements on Fluo-3 loaded olfactory EC continuously exposed to odorants for 3 h. (A) No odorant addition (control), (B) vehicle, (C) ethyl vanillin (EV), (D) LY83583 + ethyl vanillin, (E) isobutyrate (Isob), (F) LY83583 + Isob, (G) camptothecin (positive control). Co ...
UNDERSTANDING THE INTRACELLULAR NICHE IN CNIDARIAN
... The nature and mechanisms of interactions of apicomplexan parasites with their hosts cells has been an active area of research and a SCOPUS search for publications on just one of the apicomplexans (Plasmodium) returns over 38 780 hits, whereas a search for “Symbiodinium OR zooxanthella” returns 1337 ...
... The nature and mechanisms of interactions of apicomplexan parasites with their hosts cells has been an active area of research and a SCOPUS search for publications on just one of the apicomplexans (Plasmodium) returns over 38 780 hits, whereas a search for “Symbiodinium OR zooxanthella” returns 1337 ...
Ciliary neurotrophic factor maintains the pluripotentiality of
... ES cells express functional CNTF receptors LIF is thus far the only factor known that can maintain ES cells, which are derived from the inner cell mass of a preimplantation mouse blastocyst, in an undifferentiated state capable of contributing to all cell lineages upon reintroduction into the embryo ...
... ES cells express functional CNTF receptors LIF is thus far the only factor known that can maintain ES cells, which are derived from the inner cell mass of a preimplantation mouse blastocyst, in an undifferentiated state capable of contributing to all cell lineages upon reintroduction into the embryo ...
Homeostatic maintenance of pathogen
... nisms (Appelberg, 2006). However, many intracellular pathogens have evolved mechanisms by which they can survive and replicate within the vacuolar environment. During infection, bacterial factors that mediate virulence, including pore-forming proteins, can damage vacuolar membranes (Aroian and van d ...
... nisms (Appelberg, 2006). However, many intracellular pathogens have evolved mechanisms by which they can survive and replicate within the vacuolar environment. During infection, bacterial factors that mediate virulence, including pore-forming proteins, can damage vacuolar membranes (Aroian and van d ...
The MHC I immunopeptidome conveys to the cell surface an
... the immune self, is plastic and moulded by cellular metabolic activity. By using a quantitative high-throughput mass spectrometry-based approach, we found that altering cellular metabolism via the inhibition of the mammalian target of rapamycin results in dynamic changes in the cell surface MIPs lan ...
... the immune self, is plastic and moulded by cellular metabolic activity. By using a quantitative high-throughput mass spectrometry-based approach, we found that altering cellular metabolism via the inhibition of the mammalian target of rapamycin results in dynamic changes in the cell surface MIPs lan ...
Ch. 3 - SBCC Biological Sciences Department
... the cell membrane, the nuclear envelope, and other organelles. The ER provides a vast tubular network that transports molecules from one cell part to another. It winds from the nucleus out toward the cell membrane. The endoplasmic reticulum participates in the synthesis of protein and lipid molecule ...
... the cell membrane, the nuclear envelope, and other organelles. The ER provides a vast tubular network that transports molecules from one cell part to another. It winds from the nucleus out toward the cell membrane. The endoplasmic reticulum participates in the synthesis of protein and lipid molecule ...
traffic jams affect plant development and signal transduction
... system also has unique components. In mammals and yeast, each cell has only one type of vacuole, whereas in plants, different types of vacuole — lytic and protein storage — frequently coexist in one cell97. It is possible that this complex vacuolar system requires a more-sophisticated transport mach ...
... system also has unique components. In mammals and yeast, each cell has only one type of vacuole, whereas in plants, different types of vacuole — lytic and protein storage — frequently coexist in one cell97. It is possible that this complex vacuolar system requires a more-sophisticated transport mach ...
Multiple mediators of plant programmed cell death: interplay of
... that are different from the fragments that remain after cleavage by an animal caspase.(9) As the proteolytic activity detected in plants may have some different specificities to animal caspases, interpretation of these data requires some caution. In animals, the IAP protein family has been postulate ...
... that are different from the fragments that remain after cleavage by an animal caspase.(9) As the proteolytic activity detected in plants may have some different specificities to animal caspases, interpretation of these data requires some caution. In animals, the IAP protein family has been postulate ...
Mary Ann Thompson Arildsen, M
... previously identified as having altered expression in leukemias and lymphomas.. We have performed functional assays to identify targets of miRNA-155, which we have previously shown to be over-expressed in all AML cases that we have studied. One target gene to which miR-155 binds is C/EBPbeta, a tr ...
... previously identified as having altered expression in leukemias and lymphomas.. We have performed functional assays to identify targets of miRNA-155, which we have previously shown to be over-expressed in all AML cases that we have studied. One target gene to which miR-155 binds is C/EBPbeta, a tr ...
OPEN - Cherry Hill Tuition
... total mark for this paper is 80. • The marks for each question are shown in brackets • The – use this as a guide as to how much time to spend on each question. labelled with an asterisk (*) are ones where the quality of your • Questions written communication will be assessed ...
... total mark for this paper is 80. • The marks for each question are shown in brackets • The – use this as a guide as to how much time to spend on each question. labelled with an asterisk (*) are ones where the quality of your • Questions written communication will be assessed ...
Identification of fat-cell enhancer regions in Drosophila melanogaster
... Figure 4. A7.1 ES-lacZ reporter recapitulates a portion of the srp expression pattern. (A) Lateral view of a stage-10 embryo. Reporter activity is first detected in the cephalic mesoderm and in PS13 in a dorsal cluster of cells, which eventually gives rise to the dorsal fat-cell projection and the p ...
... Figure 4. A7.1 ES-lacZ reporter recapitulates a portion of the srp expression pattern. (A) Lateral view of a stage-10 embryo. Reporter activity is first detected in the cephalic mesoderm and in PS13 in a dorsal cluster of cells, which eventually gives rise to the dorsal fat-cell projection and the p ...
Provisional PDF - BioMed Central
... can be identified from gene expression information. However, this is not the case for exons. Complicated species of alternative isoforms with small numbers of nucleotide changes can be predicted compared with genes. Thus, the quantitative credibility of an exon’s information is generally much less t ...
... can be identified from gene expression information. However, this is not the case for exons. Complicated species of alternative isoforms with small numbers of nucleotide changes can be predicted compared with genes. Thus, the quantitative credibility of an exon’s information is generally much less t ...
Article Integrin-Dependent Organization and Bidirectional Vesicular Traffic at Cytotoxic Immune Synapses Immunity
... with NK cells stimulated by Phorbol 12-myristate 13-acetate (PMA) and ionomycin on a lipid bilayer carrying ICAM-1. Approximately 15 min after stimulation, NK cells acquired CD107a Fab staining (Figure S3A). Clusters of exocytosed LAMP-1 then appeared, and their distribution was dynamic and disperse ...
... with NK cells stimulated by Phorbol 12-myristate 13-acetate (PMA) and ionomycin on a lipid bilayer carrying ICAM-1. Approximately 15 min after stimulation, NK cells acquired CD107a Fab staining (Figure S3A). Clusters of exocytosed LAMP-1 then appeared, and their distribution was dynamic and disperse ...
Cell types
... Cell types Trichomes Trichomes can appear as singular "hairs" or they can be branched as seen in these two stellate trichomes. Trichome shape is indicative of a particular plant species and has been used in taxonomy to identify plants. ...
... Cell types Trichomes Trichomes can appear as singular "hairs" or they can be branched as seen in these two stellate trichomes. Trichome shape is indicative of a particular plant species and has been used in taxonomy to identify plants. ...
Antiproliferative and apoptotic effects of O
... in a time- and dose-dependent manner and with a higher efficiency than DFO. Mitotic index was also strongly decreased by TRX and, unexpectedly, DFO inhibited mitotic activity to the same extent as TRX, thus there is a discrepancy between the slight reduction in DNA synthesis and a large decrease in ...
... in a time- and dose-dependent manner and with a higher efficiency than DFO. Mitotic index was also strongly decreased by TRX and, unexpectedly, DFO inhibited mitotic activity to the same extent as TRX, thus there is a discrepancy between the slight reduction in DNA synthesis and a large decrease in ...
BOTANY FOLDABLES FOR CH 23
... INSIDE: open or indeterminate, type of growth. They grow and produce new cells at the _________________________________________ for as long as they live. These cells are produced in _________________________. OUTSIDE: Meristem INSIDE: (you provide the definition) OUTSIDE: New cells produced from ind ...
... INSIDE: open or indeterminate, type of growth. They grow and produce new cells at the _________________________________________ for as long as they live. These cells are produced in _________________________. OUTSIDE: Meristem INSIDE: (you provide the definition) OUTSIDE: New cells produced from ind ...
Review The Role of Laminin in Embryonic Cell Polarization and
... revealed that loss of either of them results in embryonic lethality, characterized by defects of cell polarity, cell adhesion, and tissue cohesion (Huang et al., 2003). In mammals, there are at least 15 laminins derived from five ␣, three , and three ␥ subunits, the ␣ subunits of which are thought ...
... revealed that loss of either of them results in embryonic lethality, characterized by defects of cell polarity, cell adhesion, and tissue cohesion (Huang et al., 2003). In mammals, there are at least 15 laminins derived from five ␣, three , and three ␥ subunits, the ␣ subunits of which are thought ...
secretion and endocytosis in insulin
... lanthanum, included in the fixative (35, 38, 70), gains access to very few such bodies, although it does reach the cell surface (Fig. 6). No obvious differences in morphology are encountered when cells from insulin-injected animals that have not received peroxidase are compared with those that have ...
... lanthanum, included in the fixative (35, 38, 70), gains access to very few such bodies, although it does reach the cell surface (Fig. 6). No obvious differences in morphology are encountered when cells from insulin-injected animals that have not received peroxidase are compared with those that have ...
Growth Factors Are Released by Mechanically Wounded
... Abstract. Growth factors may be required at sites of ...
... Abstract. Growth factors may be required at sites of ...
... Due to the lack of a complete urea cycle, uricotelic species, such as broilers, are not able to synthesize de novo arginine (Arg), thus depending exclusively on dietary Arg. High levels of dietary lysine (Lys) increase the demand for Arg because of the antagonistic relationship between these amino a ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.