A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila. Nature Cell Biology 3, 848-851. pdf
... membrane proteins, so they can influence chromosome organization and possibly gene expression6,10,16. gurken transcripts are synthesized in the oocyte nucleus and must interact with the Squid hnRNP protein and possibly K10, a putative RNA-binding protein, in order to localize properly after export i ...
... membrane proteins, so they can influence chromosome organization and possibly gene expression6,10,16. gurken transcripts are synthesized in the oocyte nucleus and must interact with the Squid hnRNP protein and possibly K10, a putative RNA-binding protein, in order to localize properly after export i ...
Syndecan-1 regulates αvß5 integrin activity in B82L fibroblasts
... ectodomain (Yamashita et al., 1999). Thus, antibody ligation of syndecans can trigger signaling leading to cell spreading, although the mechanisms of signaling are not clear. Some studies demonstrate that the cellular response to the extracellular matrix involves engagement and cooperative signaling ...
... ectodomain (Yamashita et al., 1999). Thus, antibody ligation of syndecans can trigger signaling leading to cell spreading, although the mechanisms of signaling are not clear. Some studies demonstrate that the cellular response to the extracellular matrix involves engagement and cooperative signaling ...
PersPeCTIves
... (barbed end or plus end (+)) is localized adjacent to the membrane — this means that the insertion of while being attached to the membrane new monomers occurs at this site. Of the different mechanisms and processes shown, only two can be surface, providing a force that contributes to considered to b ...
... (barbed end or plus end (+)) is localized adjacent to the membrane — this means that the insertion of while being attached to the membrane new monomers occurs at this site. Of the different mechanisms and processes shown, only two can be surface, providing a force that contributes to considered to b ...
Microtubules do not promote mitotic slippage when the spindle
... Several factors influence the rate of slippage including the species the cell is from and its genotype. In general, cells from rodents are more resistant to spindle poisons and slip through an active SAC more rapidly than those from primates (Kung et al., 1990). For example, when spindle assembly is ...
... Several factors influence the rate of slippage including the species the cell is from and its genotype. In general, cells from rodents are more resistant to spindle poisons and slip through an active SAC more rapidly than those from primates (Kung et al., 1990). For example, when spindle assembly is ...
4)Cell wall
... 1-They are heterotrophs. That is, they cannot manufacture their own food from simple compounds as plants are able to do. So they are dependent on other organisms to produce their foods, e.g., sugars, starches, proteins, fats, etc. Fungi can be further divided into saprobes, parasites, symbionts, fac ...
... 1-They are heterotrophs. That is, they cannot manufacture their own food from simple compounds as plants are able to do. So they are dependent on other organisms to produce their foods, e.g., sugars, starches, proteins, fats, etc. Fungi can be further divided into saprobes, parasites, symbionts, fac ...
Learning about the Importance of Mutation
... translated to clinical oncology, probably in the patients with an early breast or prostate cancer, their sera still favor the patients’ health by containing cancer cell specific killing or inhibiting components released from the normal cells. These data dovetail with the so-called “neighboring suppr ...
... translated to clinical oncology, probably in the patients with an early breast or prostate cancer, their sera still favor the patients’ health by containing cancer cell specific killing or inhibiting components released from the normal cells. These data dovetail with the so-called “neighboring suppr ...
Identification of Amino Acid Residues within GABAA Receptor
... expression of homomeric b subunits. Live A293 cells were labeled by immunofluorescence using FL AG antibody followed by an Alexa 488-conjugated secondary antibody and analyzed by FACS. Figure 4 A shows typical results for mock-transfected A293 cells or cells expressing (FL AG)b2 or (FL AG)b3. E xpre ...
... expression of homomeric b subunits. Live A293 cells were labeled by immunofluorescence using FL AG antibody followed by an Alexa 488-conjugated secondary antibody and analyzed by FACS. Figure 4 A shows typical results for mock-transfected A293 cells or cells expressing (FL AG)b2 or (FL AG)b3. E xpre ...
Surface modified poly(β amino ester)
... The use of biodegradable polymers provides a potentially safe and effective alternative to viral and liposomal vectors for the delivery of plasmid DNA to cells for gene therapy applications. In this work we describe the formulation of a novel nanoparticle (NP) system containing a blend of poly(lacti ...
... The use of biodegradable polymers provides a potentially safe and effective alternative to viral and liposomal vectors for the delivery of plasmid DNA to cells for gene therapy applications. In this work we describe the formulation of a novel nanoparticle (NP) system containing a blend of poly(lacti ...
Protein Kinase C Activators Inhibit Receptor
... within closed caveolae. After the caveolae seal off from the extracellular space, the folate dissociates from the receptor and diffuses through a membrane carder into the cytoplasm (21). The vitamin becomes polyglutamylated as soon as it reaches the cytoplasm, which prevents diffusion out of the cel ...
... within closed caveolae. After the caveolae seal off from the extracellular space, the folate dissociates from the receptor and diffuses through a membrane carder into the cytoplasm (21). The vitamin becomes polyglutamylated as soon as it reaches the cytoplasm, which prevents diffusion out of the cel ...
BSC-110 Biology
... A. Define these basic terms: atom, atomic number, atomic mass, element, ion, isotope, and molecule B. Use the periodic table to identify the elements found in a living system C. Recognize energy levels, electron capacities of an energy level and how stability of atoms is determined D. ...
... A. Define these basic terms: atom, atomic number, atomic mass, element, ion, isotope, and molecule B. Use the periodic table to identify the elements found in a living system C. Recognize energy levels, electron capacities of an energy level and how stability of atoms is determined D. ...
Protein Kinase A Activation Down-Regulates, Whereas Extracellular
... has been demonstrated in specific brain areas of methamphetamine- or cocaine-sensitized rats (Itzhak, 1993; Liu et al., 2005). We found that Sig-1Rs were up-regulated by 50% in the midbrain of rats self-administering methamphetamine in a response-contingent manner (Stefanski et al., 2004). Up-regula ...
... has been demonstrated in specific brain areas of methamphetamine- or cocaine-sensitized rats (Itzhak, 1993; Liu et al., 2005). We found that Sig-1Rs were up-regulated by 50% in the midbrain of rats self-administering methamphetamine in a response-contingent manner (Stefanski et al., 2004). Up-regula ...
Intracellular pH
... late eNOS activity.2 At the level of gene expression, eNOS levels may be influenced by direct binding of transcription factors to the eNOS promoter or by affecting mRNA stability. The subcellular location may also modulate eNOS activity. Within the cell, eNOS targets the Golgi complex and plasmalemm ...
... late eNOS activity.2 At the level of gene expression, eNOS levels may be influenced by direct binding of transcription factors to the eNOS promoter or by affecting mRNA stability. The subcellular location may also modulate eNOS activity. Within the cell, eNOS targets the Golgi complex and plasmalemm ...
Overexpression of a truncated cyclin B gene arrests Dictyostelium
... Total RNA was extracted from cells by the acid guanidinium thiocyanate method (Chomczynski and Sacchi, 1987). In order to reduce the hybridization background caused by the presence of the high copy number of the transgene in the transformants, the RNA preparations were resuspended in 500 µl of RES-1 ...
... Total RNA was extracted from cells by the acid guanidinium thiocyanate method (Chomczynski and Sacchi, 1987). In order to reduce the hybridization background caused by the presence of the high copy number of the transgene in the transformants, the RNA preparations were resuspended in 500 µl of RES-1 ...
Manipulating Mammalian Genome by Gene Targeting
... anterior commissure, resulting in a failure of neurons to link the temporal lobes (7). However, Nuk is a ...
... anterior commissure, resulting in a failure of neurons to link the temporal lobes (7). However, Nuk is a ...
Analysis of tissue flow patterns during primitive streak formation in
... cell displacements; the cells in labelled patches stayed close together. Closer inspection of the groups of labelled cells revealed that cells from individual patches split up into several smaller units, but we could not determine whether these splits were due to adjacent cells moving apart or cells ...
... cell displacements; the cells in labelled patches stayed close together. Closer inspection of the groups of labelled cells revealed that cells from individual patches split up into several smaller units, but we could not determine whether these splits were due to adjacent cells moving apart or cells ...
THE PLANT CELL CYCLE Walter Dewitte and James A.H. Murray
... Differentiating plant cells often display an alternative cycle known as endoreduplication, characterized by an increase in the nuclear ploidy level that results from repeated S phases with no intervening mitosis (61). In some species, such as Arabidopsis, this produces ploidy levels up to 32C in the ...
... Differentiating plant cells often display an alternative cycle known as endoreduplication, characterized by an increase in the nuclear ploidy level that results from repeated S phases with no intervening mitosis (61). In some species, such as Arabidopsis, this produces ploidy levels up to 32C in the ...
Cell-A-Brate - 6.LS.1 - Columbus City Schools
... CCSS.ELA-Literacy.RST.6-8.1 Cite specific textual evidence to support analysis of science and technical texts. CCSS.ELA-Literacy.RST.6-8.2 Determine the central ideas or conclusions of a text; provide an accurate summary of the text distinct from prior knowledge or opinions. CCSS.ELA-Literacy.RST.6- ...
... CCSS.ELA-Literacy.RST.6-8.1 Cite specific textual evidence to support analysis of science and technical texts. CCSS.ELA-Literacy.RST.6-8.2 Determine the central ideas or conclusions of a text; provide an accurate summary of the text distinct from prior knowledge or opinions. CCSS.ELA-Literacy.RST.6- ...
Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells
... Lineage-depleted BM cells were further analyzed for the expression of CD34, c-Kit, Sca-1, and Endomucin. Most CD34KSL cells (71%) strongly expressed Endomucin (Fig. 3 A). Although the expression level of Endomucin on CD34KSL cells was relatively low compared with that on CD34KSL cells, Endomucin ...
... Lineage-depleted BM cells were further analyzed for the expression of CD34, c-Kit, Sca-1, and Endomucin. Most CD34KSL cells (71%) strongly expressed Endomucin (Fig. 3 A). Although the expression level of Endomucin on CD34KSL cells was relatively low compared with that on CD34KSL cells, Endomucin ...
Ploidy of Bacillus subtilis exfusants: the haploid nature of cells
... prokaryotic cell is its permanently haploid state. The presence of two genomes in spores of some spore-forming bacillisuch as Bacillus megateriumor Bacillus cereus is not paralleled by permanent diploidy during exponential growth. The quantity of DNA per cell varies during the cell cycle and it has ...
... prokaryotic cell is its permanently haploid state. The presence of two genomes in spores of some spore-forming bacillisuch as Bacillus megateriumor Bacillus cereus is not paralleled by permanent diploidy during exponential growth. The quantity of DNA per cell varies during the cell cycle and it has ...
Expression of truncated Sek-1 receptor tyrosine kinase
... they do with cells from r2, r4 and r6 (Guthrie et al., 1993). Similarly, cells from r2, r4 and r6 are more miscible with each other than they are with r3 or r5. Cell adhesion properties that alternate between rhombomeres may therefore restrict cell movement across boundaries, and cell sorting could ...
... they do with cells from r2, r4 and r6 (Guthrie et al., 1993). Similarly, cells from r2, r4 and r6 are more miscible with each other than they are with r3 or r5. Cell adhesion properties that alternate between rhombomeres may therefore restrict cell movement across boundaries, and cell sorting could ...
Phenotypic Heterogeneity Affects
... Gerdes, 2014). The persister phenotype depends on various factors such as the level of signaling nucleotide (p)ppGpp, and various metabolic activities (Maisonneuve et al., 2013; Amato et al., 2014). Thereby it is well accepted that toxin–antitoxin (TA) systems play a key role in the regulatory netwo ...
... Gerdes, 2014). The persister phenotype depends on various factors such as the level of signaling nucleotide (p)ppGpp, and various metabolic activities (Maisonneuve et al., 2013; Amato et al., 2014). Thereby it is well accepted that toxin–antitoxin (TA) systems play a key role in the regulatory netwo ...
Targeted expression of SV40 T antigen in the hair follicle of
... of novel consensus sequences in the 5′ flanking regions of these genes is useful as an indicator of the possible involvement of transcription factors and the complexity of transcriptional regulation. However, the functional importance of these proposed regulatory sequences must now be confirmed. The ...
... of novel consensus sequences in the 5′ flanking regions of these genes is useful as an indicator of the possible involvement of transcription factors and the complexity of transcriptional regulation. However, the functional importance of these proposed regulatory sequences must now be confirmed. The ...
The TOR signalling network from yeast to man
... TORC2 substrates include SLM1 and SLM2, a homologous pair of PH domain containing proteins, and the AGC kinase YPK2 (Levin, 2005). SLM1/2 and YPK2 are all required for polarization of the actin cytoskeleton but the mechanisms by which these yTORC2 substrates impinge upon ROM2 have not yet been eluci ...
... TORC2 substrates include SLM1 and SLM2, a homologous pair of PH domain containing proteins, and the AGC kinase YPK2 (Levin, 2005). SLM1/2 and YPK2 are all required for polarization of the actin cytoskeleton but the mechanisms by which these yTORC2 substrates impinge upon ROM2 have not yet been eluci ...
Biology I Syllabus
... Unit 9: Animals and Relationships Among Organisms (Weeks 27-30) This unit addresses how organisms are classified into a hierarchy or groups and subgroups based on similarities that reflect their evolutionary relationships and the identification the major types of animal cells and tissues. Additional ...
... Unit 9: Animals and Relationships Among Organisms (Weeks 27-30) This unit addresses how organisms are classified into a hierarchy or groups and subgroups based on similarities that reflect their evolutionary relationships and the identification the major types of animal cells and tissues. Additional ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.