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Activation of different myogenic pathways: myf-5 is
Activation of different myogenic pathways: myf-5 is

... absence of the neural tube. A quantitative analysis, summarizing more than 20 experiments is reported in Fig. 3. It is clear from the data that the axial structures are required for optimal differentiation of UPM or newly formed somite(s), but that differentiation can also be induced by dorsolateral ...
Activation of different myogenic pathways: myf
Activation of different myogenic pathways: myf

... absence of the neural tube. A quantitative analysis, summarizing more than 20 experiments is reported in Fig. 3. It is clear from the data that the axial structures are required for optimal differentiation of UPM or newly formed somite(s), but that differentiation can also be induced by dorsolateral ...
Respiration Webquest
Respiration Webquest

... Fermentation – A Pathway Without Oxygen: Go to Cellular Respiration. Scroll down the article until you reach the section on fermentation. Read that section. 10. Explain the difference between ethanol fermentation and lactic acid fermentation. ...
From spores to antibiotics via the cell cycle
From spores to antibiotics via the cell cycle

Pausing of Golgi Bodies on Microtubules Regulates
Pausing of Golgi Bodies on Microtubules Regulates

... Plant growth and organ formation depend on the oriented deposition of load-bearing cellulose microfibrils in the cell wall. Cellulose is synthesized by plasma membrane–bound complexes containing cellulose synthase proteins (CESAs). Here, we establish a role for the cytoskeleton in intracellular traf ...
Cellular Respiration Webquest (word)
Cellular Respiration Webquest (word)

... Fermentation – A Pathway Without Oxygen: Go to Cellular Respiration. Scroll down the article until you reach the section on fermentation. Read that section. 10. Explain the difference between ethanol fermentation and lactic acid fermentation. ...
Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO
Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO

... Pex5p and affecting Pex14p stability. We also address a novel role for Pex5p in Pex14p stability via the fifth pentapeptide motif. ...
Rat maf related genes: specific expression in chondrocytes
Rat maf related genes: specific expression in chondrocytes

... Ets-1, a transcription factor containing a helix ± turn ± helix DNA binding domain, inhibits Ets-1 activity, thus interrupting erythroid di€erentiation (Sieweke et al., 1996). Maf-family transcription factors heterodimerize not only with bZip proteins, but also with helix ± turn ± helix proteins. Th ...
The Epithelial Glycoprotein 2 (EGP-2) Promoter
The Epithelial Glycoprotein 2 (EGP-2) Promoter

2009-2010 Course Syllabus for Intro to Biology
2009-2010 Course Syllabus for Intro to Biology

... Importance of ions in biological processes b. Develop a logical argument defending water as an essential component of living systems (e.g., unique bonding and properties including polarity, high specific heat, surface tension, hydrogen bonding, adhesion, cohesion, and expansion upon freezing). (DOK ...
Wood Chemistry - Fundamentals and Application
Wood Chemistry - Fundamentals and Application

... of cellulose, hemicellulose, and lignin found in their biomass and, further, important differences in the types of hemicelluloses and/or the ratios of monomers in lignin. ...
Morphology and physiology of the marine straminipilan fungi, the
Morphology and physiology of the marine straminipilan fungi, the

... the equatorial Indian Ocean. None of the samples yielded thraustochytrids in culture, suggesting that aplanochytrids might be more prevalent in the zooplankton samples of these waters than thraustochytrids. Fourteen isolates of aplanochytrids were studied with reference to their colony and cell morp ...
Agrin is required for survival and function of
Agrin is required for survival and function of

... isoforms but carry a transgene that increases Musk expression selectively in skeletal muscle.11 Musk expression in skeletal muscle allows agrin knockout mice to live longer, but still most Musk-L; Agrn⫺/⫺ mice die between postnatal day (P) 7 and P10 for unknown reasons11 and our experiments were the ...
Author`s personal copy
Author`s personal copy

... cell cycle lengthening. For example, in Xenopus the nucleocytoplasmic (N/C) ratio increases with each round of cell division causing the titration of an as yet unidentified factor leading to a lengthening of S phase at the midblastula transition or MBT (Newport and Kirschner, 1982a; Vastag et al., 20 ...
Gene Section BTK (Bruton agammaglobulinemia tyrosine kinase) Atlas of Genetics and Cytogenetics
Gene Section BTK (Bruton agammaglobulinemia tyrosine kinase) Atlas of Genetics and Cytogenetics

... Btk as a tumor suppressor in pre-B cell leukemia in mice Expression of the pre-B cell receptor (pre-BCR) leads to activation of the adaptor molecule Slp65 (also termed Bash or Blnk) and Btk. Spontaneous pre-B cell leukemia development in Slp65-deficient mice demonstrate that Slp65 acts as a tumor su ...
Staphylococcal phenomics: metabolomic and proteomic responses
Staphylococcal phenomics: metabolomic and proteomic responses

... embedded in stress response regulatory mechanisms via complex pathways. In the presence of stress, chaperons and proteases assist by unfolding proteins and also help in monitoring the expression of many transcriptional factors [24]. In addition to chaperons and protease, proteolysis mechanisms are c ...
Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast.
Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast.

... form and motility to cilia and flagella. A central property of microtubules is that they are dynamic; at steady state, individual microtubules can independently alternate between periods of stability (lengthening) and instability (shrinking) (Mitchison and Kirschner, 1984). This dynamic instability ...
Evidence that Shh cooperates with a retinoic acid inducible co
Evidence that Shh cooperates with a retinoic acid inducible co

... cells. Overall, these results suggest that production and processing of Shh protein in P19 cells occurs in a similar fashion to that shown in a variety of other cell types as well as in vivo (Bumcrot et al., 1995 and Lopez Martinez et al., 1995). Retinoic acid and Sonic hedgehog are required for ZPA ...
Quantitative phase microscopy – a new tool for investigating
Quantitative phase microscopy – a new tool for investigating

... images by the QPM method can be used to emulate other contrast image modes (including DIC and HMC) for qualitative viewing. QPM achieves improved discrimination of cellular detail, which permits more rigorous image analysis procedures to be undertaken when compared with conventional optical methods. ...
ForC, a novel type of formin family protein lacking an FH1 domain, is
ForC, a novel type of formin family protein lacking an FH1 domain, is

... clustalW 1.8 and determined their FH2 and FH3 domains. A domain situated between FH2 and FH3 and containing multiple poly-proline stretches was designated as FH1. forA encodes a polypeptide of 1219 amino acids; its FH1, FH2 and FH3 domains are located between amino acid residues 650-765, 904-1039 an ...
The TACC proteins: TACC-ling microtubule dynamics and
The TACC proteins: TACC-ling microtubule dynamics and

... TACC3 has a role during cell division, in particular during development. Indeed, TACC3-deficient mice show embryonic lethality, associated with a greatly reduced cell number, widespread apoptotic cell death, and mitotic defects [36,37]. Interestingly, this phenotype was partially rescued in mice tha ...
Molecular mechanisms of Salmonella invasion
Molecular mechanisms of Salmonella invasion

... of Salmonella virulence provided by these studies are believed to be highly relevant to the understanding of the natural infection process [25, 28, 50]. The ability of S. typhimurium to invade ...
Heat Shock Responses for Understanding Diseases of
Heat Shock Responses for Understanding Diseases of

... and killing foreign microorganisms in phagocytic cells, have been extensively studied. The ROS defense system requires the NADPH oxidase complex (Nox), which generates H2O2 within the phagosome. Invasion by microorganisms leads to assembly of an active Nox complex, which comprises a catalytic subuni ...
Plant mitochondria move on F-actin, but their positioning in the
Plant mitochondria move on F-actin, but their positioning in the

... After complete disruption of the F-actin, the mitochondria parked themselves into conspicuous parallel arrays transverse or oblique to the cell axis or clustered around chloroplasts and around patches and strands of endoplasmic reticulum. Oryzalin inhibited all positioning of the mitochondria in par ...
Pausing of Golgi Bodies on Microtubules Regulates
Pausing of Golgi Bodies on Microtubules Regulates

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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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