Title Soybean extracts increase cell surface ZIP4 abundance and
... increase ZIP4 could potentially enhance zinc absorption by the intestine. In this study, we used mouse Hepa cells, which regulate mouse Zip4 (mZip4) in a manner indistinguishable from that in intestinal enterocytes, to screen for suitable food components able to increase the abundance of ZIP4. Using ...
... increase ZIP4 could potentially enhance zinc absorption by the intestine. In this study, we used mouse Hepa cells, which regulate mouse Zip4 (mZip4) in a manner indistinguishable from that in intestinal enterocytes, to screen for suitable food components able to increase the abundance of ZIP4. Using ...
Control of cell pattern in the neural tube: regulation of cell
... To identify signals that might regulate cell differentiation within the neural tube, we have searched for genes encoding secreted factors that are expressed in a restricted manner along the dorsoventral axis of the neural tube. We have focused on the transforming growth factor 8 (TGF8) family since ...
... To identify signals that might regulate cell differentiation within the neural tube, we have searched for genes encoding secreted factors that are expressed in a restricted manner along the dorsoventral axis of the neural tube. We have focused on the transforming growth factor 8 (TGF8) family since ...
PDF
... Many aspects of glial development are intimately tied to neurongenerated signals through either direct cell-cell contact or secreted factors (Newbern and Birchmeier, 2010). Other than neurons, regulatory signals are also provided to glia by the extracellular matrix (ECM) and adjacent glia. Integrins ...
... Many aspects of glial development are intimately tied to neurongenerated signals through either direct cell-cell contact or secreted factors (Newbern and Birchmeier, 2010). Other than neurons, regulatory signals are also provided to glia by the extracellular matrix (ECM) and adjacent glia. Integrins ...
Myosin-Powered Membrane Compartment Drives Cytoplasmic
... How molecules and large macromolecular complexes are properly distributed and positioned is one of the central problems of cell biology. In relatively small prokaryotic cells, which lack endomembrane compartments, diffusion modulated by the cell’s metabolic status is a major mechanism at work for tr ...
... How molecules and large macromolecular complexes are properly distributed and positioned is one of the central problems of cell biology. In relatively small prokaryotic cells, which lack endomembrane compartments, diffusion modulated by the cell’s metabolic status is a major mechanism at work for tr ...
Actin branching in the initiation and maintenance of lamellipodia
... that single cells could repair wounds inflicted in the cytoplasm by a microneedle and that wound closure involved the induction of lamellipodia like structures, containing both actin and Arp2/3 complex components. We have adapted the same assay to vertebrate cells and have exploited this model syste ...
... that single cells could repair wounds inflicted in the cytoplasm by a microneedle and that wound closure involved the induction of lamellipodia like structures, containing both actin and Arp2/3 complex components. We have adapted the same assay to vertebrate cells and have exploited this model syste ...
Full-Text PDF
... inflammation enhances the susceptibility of pneumonia in the elderly populations. A previous study reported that elevated tumor necrosis factor (TNF)-α and interleukin (IL)-6 levels positively correlated with the incidence of pneumonia in healthy elderly individuals [17]. Other studies demonstrated ...
... inflammation enhances the susceptibility of pneumonia in the elderly populations. A previous study reported that elevated tumor necrosis factor (TNF)-α and interleukin (IL)-6 levels positively correlated with the incidence of pneumonia in healthy elderly individuals [17]. Other studies demonstrated ...
Comparison of Polysaccharides Produced by
... mgalactose were determined using the appropriate oxidase-based procedures on material after hydrolysis in 0.5 M-H,SO, (100"C for 4 h) and neutralization with Amberlite resin I Q I Oin the bicarbonate form. Total amino sugar was assayed in hydrolysates (6 M-HCl at IOO "Cfor 6 h) after evaporation of ...
... mgalactose were determined using the appropriate oxidase-based procedures on material after hydrolysis in 0.5 M-H,SO, (100"C for 4 h) and neutralization with Amberlite resin I Q I Oin the bicarbonate form. Total amino sugar was assayed in hydrolysates (6 M-HCl at IOO "Cfor 6 h) after evaporation of ...
FURTHER STUDIES ON THE THETA CELL OF THE MOUSE
... Theta cells show dense aggregations of the endoplasmic reticulum at the cell periphery corresponding with the basophilic region observed by light microscopy (Fig. 1). In this area, membranebounded cavities of the endoplasmic reticulum are very flattened and extend to distant areas. The contents of t ...
... Theta cells show dense aggregations of the endoplasmic reticulum at the cell periphery corresponding with the basophilic region observed by light microscopy (Fig. 1). In this area, membranebounded cavities of the endoplasmic reticulum are very flattened and extend to distant areas. The contents of t ...
Hox11 genes are required for regional patterning
... integration of muscles, tendons and bones. The molecular mechanisms involved in the differentiation of each of these tissues have been the focus of significant research; however, much less is known about how these tissues are integrated into a functional unit appropriate for each body position and r ...
... integration of muscles, tendons and bones. The molecular mechanisms involved in the differentiation of each of these tissues have been the focus of significant research; however, much less is known about how these tissues are integrated into a functional unit appropriate for each body position and r ...
Ion-channel blocker sensitivity of voltage-gated
... subunits, overall amino acid sequence identity between Cch1 and a1 subunits is low: e.g. 24 % for Cch1 versus an L-type mammalian VGCC (Paidhungat & Garrett, 1997). It is noteworthy that one of the four S4 segments of Cch1 lacks most of the positively charged residues crucial for voltage sensing. In ...
... subunits, overall amino acid sequence identity between Cch1 and a1 subunits is low: e.g. 24 % for Cch1 versus an L-type mammalian VGCC (Paidhungat & Garrett, 1997). It is noteworthy that one of the four S4 segments of Cch1 lacks most of the positively charged residues crucial for voltage sensing. In ...
siRNA back - Santa Cruz Biotechnology
... (Fluorescein Conjugates): sc-36869, sc-44239, sc-44240 or sc-44241. Each contain a scrambled sequence that will not lead to the specific degradation of any known cellular mRNA. ...
... (Fluorescein Conjugates): sc-36869, sc-44239, sc-44240 or sc-44241. Each contain a scrambled sequence that will not lead to the specific degradation of any known cellular mRNA. ...
Germ cell loss in the XXY male mouse: Altered X
... testis. Although no such bias against XX Leydig cells has been reported, these cells have been suggested to be functionally defective and unable to support spermatogenesis (Patek et al., 1991; Singh et al., 1987). Thus the study of XX Sxr males and XX/XY chimeric testes has provided some insight int ...
... testis. Although no such bias against XX Leydig cells has been reported, these cells have been suggested to be functionally defective and unable to support spermatogenesis (Patek et al., 1991; Singh et al., 1987). Thus the study of XX Sxr males and XX/XY chimeric testes has provided some insight int ...
PIPing on lysosome tubes
... (Settembre et al, 2011; Efeyan et al, 2012). The membrane of the lysosome, protected from the degradative enzymes contained in the lumen by highly glycosylated lysosomal membrane proteins (LAMPs, LIMPs, etc.), contains the machinery for its acidification (V-ATPase), as well as a variety of transport ...
... (Settembre et al, 2011; Efeyan et al, 2012). The membrane of the lysosome, protected from the degradative enzymes contained in the lumen by highly glycosylated lysosomal membrane proteins (LAMPs, LIMPs, etc.), contains the machinery for its acidification (V-ATPase), as well as a variety of transport ...
Morphine Modulates Mouse Hippocampal Progenitor Cell Lineages
... putative downstream targets of NeuroD1 [16]. Meanwhile, as its most well known role, Notch1 maintains NPCs in the undifferentiated state by inhibiting neuronal differentiation. It was reported that Notch1 inhibits neurogenesis by turning CSL-SKIP into an activator and stimulating the transcription o ...
... putative downstream targets of NeuroD1 [16]. Meanwhile, as its most well known role, Notch1 maintains NPCs in the undifferentiated state by inhibiting neuronal differentiation. It was reported that Notch1 inhibits neurogenesis by turning CSL-SKIP into an activator and stimulating the transcription o ...
- University of East Anglia
... which express the heparan sulfate proteoglycan GPC4 (Serralbo and Marcelle, 2014). Overexpression of Wnt3a in half of the neural tube leads to an increase in the number of dorsal/dermomyotomal cells and a marked enlargement of the myotome (Galli et al., 2004). Consistent with this finding, retrovir ...
... which express the heparan sulfate proteoglycan GPC4 (Serralbo and Marcelle, 2014). Overexpression of Wnt3a in half of the neural tube leads to an increase in the number of dorsal/dermomyotomal cells and a marked enlargement of the myotome (Galli et al., 2004). Consistent with this finding, retrovir ...
Mechanisms of water-holding capacity of meat: The role
... made toward understanding the mechanisms that underlie the development of drip or purge. It is clear that early postmortem events including rate and extent of pH decline, proteolysis and even protein oxidation are key in influencing the ability of meat to retain moisture. Much of the water in the mus ...
... made toward understanding the mechanisms that underlie the development of drip or purge. It is clear that early postmortem events including rate and extent of pH decline, proteolysis and even protein oxidation are key in influencing the ability of meat to retain moisture. Much of the water in the mus ...
The Relation Between Scale and the Completeness of Pattern in
... dient profile in the signal, then each set of evolution have acquired mechanisms to asprocesses that has been postulated places sure them of this? its own constraints on the actual performance that would be expected on the part Experiments on the amphibian pattern of the regulatory system as studied ...
... dient profile in the signal, then each set of evolution have acquired mechanisms to asprocesses that has been postulated places sure them of this? its own constraints on the actual performance that would be expected on the part Experiments on the amphibian pattern of the regulatory system as studied ...
Cyclic AMP-Mediated Inhibition of Cell Growth Requires the Small G
... Cell culturing conditions and treatments. Hek293 and NIH 3T3 cells were cultured in Dulbecco modified Eagle medium (DMEM) plus 10% fetal calf serum at 37°C in 5% CO2. Cells were maintained in serum-free DMEM for 16 h at 37°C in 5% CO2 prior to treatment with various reagents for coimmunoprecipitatio ...
... Cell culturing conditions and treatments. Hek293 and NIH 3T3 cells were cultured in Dulbecco modified Eagle medium (DMEM) plus 10% fetal calf serum at 37°C in 5% CO2. Cells were maintained in serum-free DMEM for 16 h at 37°C in 5% CO2 prior to treatment with various reagents for coimmunoprecipitatio ...
Jasmonate Controls Leaf Growth by Repressing
... (student sponsorship to M.B.), and by the Japan Society for the Promotion of Science (to A.D.). ...
... (student sponsorship to M.B.), and by the Japan Society for the Promotion of Science (to A.D.). ...
PDF - Breast Cancer Research
... enzymatic activities of lysosomal hydrolases. Consequently, we determined the activities of three major lysosomal enzymes found in the mammary gland: cathepsin B, β-N-acetylhexosaminidase, and acid phosphatase. The activities of all of the enzymes investigated were statistically higher in day 4 invo ...
... enzymatic activities of lysosomal hydrolases. Consequently, we determined the activities of three major lysosomal enzymes found in the mammary gland: cathepsin B, β-N-acetylhexosaminidase, and acid phosphatase. The activities of all of the enzymes investigated were statistically higher in day 4 invo ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).