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Active gel physics
Active gel physics

... expansion, this velocity is proportional to �µ. Note that other terms specific to polar systems—but not associated with irreversibility— link the fluxes to hydrodynamic shear. For the dynamics of orientational order, active terms for nematic and polar systems are different. The dynamic equation of th ...
HGF and TGFβ1 differently influenced Wwox regulatory function on
HGF and TGFβ1 differently influenced Wwox regulatory function on

... from squamous cell carcinoma [13]. Although EMT seems a transient process, present at least only at the invasive front of carcinomas, while MET being the driving force for metastatic colonization [7], the molecular regulators that promote MET transition, critical for the formation of bone metastasis ...
Bacterial chromosome segregation
Bacterial chromosome segregation

... XerCD recombinases bound to the dif sites that become trapped in the closing septum. In the presence of chromosome dimers FtsK can load onto DNA close to the dif locus and cause a conformational switch in turn activating Xer recombination. The C-terminal domain of FtsK, which functions as a hexameri ...
(4) staining
(4) staining

... - In a routine histological technique, stained tissue sections are mounted in a mounting medium soluble in an organic solvent, such as xylene. - So tissue sections must be dehydrated in a serious of gradually increasing concentration of alcohol before passing to xylene. - If tissue does not cleared ...
Thesis Reference - Archive ouverte UNIGE
Thesis Reference - Archive ouverte UNIGE

... Leishmaniasis is a parasitic disease transmitted to humans through sand fly bites. Clinical symptoms vary from self-healing cutaneous lesions to death. Cutaneous leishmaniasis is particularly studied in mice inoculated with Leishmania major. In this model, some strains (e.g. C57BL/6) are resistant d ...
mast cells and basophils
mast cells and basophils

... consists of a tetrameric complex of α-, β- and two γchains [60–62]. The α-chain has a long extracellular domain, which contains two immunoglobulin-like loops. The evidence suggests that the second of these loops binds a region of the Cε3 on the IgE molecule, and that the IgE molecule takes up a conv ...
High-Performance Exosome Purification
High-Performance Exosome Purification

... When isolating vesicles, it is crucial to use systems that are able to separate them, to avoid cross-contamination. At the same time, there is a need for increased size and concentration accuracy, as well as enhanced workflow. Exosomes are membrane vesicles (~ 30–120 nm in diameter) released by almo ...
Structure-Function Relationships of Stem Cell Factor
Structure-Function Relationships of Stem Cell Factor

... cytokines as diverse as growth hormone, GM-CSF, and interleukin (IL)-4, our resultssuggest that cytokinesof multiple classes share a common functional organization. 0 1996 by The American Society of Hematology. ...
Microtubules Regulate Dynamic Organization of Vacuoles in
Microtubules Regulate Dynamic Organization of Vacuoles in

... actin microfilaments, rather than microtubules, and that their maintenance and distribution are actin dependent (Ovecka et al. 2005, Higaki et al. 2006). To investigate vacuolar morphology and its regulatory mechanisms, we have, in this study, established a new visualization system using the moss, Ph ...
Monolignol glucosides as intermediate compounds in
Monolignol glucosides as intermediate compounds in

... synthesis of coniferin and a slow turnover of this compound (Marcinowski and Grisebach 1977). The concentration of coniferin in differentiating xylem of Japanese black pine (Pinus thunbergii Parl.) is highest at the beginning of May, before the most active lignifying season, June and July, and there ...
Drac1 and Crumbs in amnioserosa morphogenesis
Drac1 and Crumbs in amnioserosa morphogenesis

... dorsal closure through effecting cell shape change in the epidermis. Studies in mammalian cells and model organisms have demonstrated the involvement of the Rho subfamily of Ras-related small GTPases in regulation of the actin cytoskeleton and cell shape, and we and others have characterized the inv ...
- Wiley Online Library
- Wiley Online Library

... Protoderm formation is one of the earliest patterning events during Arabidopsis embryogenesis, taking place at the transition from the octant to the dermatogen stage, when the eight cells of the embryo proper divide tangentially (Figure 2a). The outer cell layer thus formed is designated the protode ...
Conditional lethality of a yeast strain expressing human RHOA in place of RHO1 .
Conditional lethality of a yeast strain expressing human RHOA in place of RHO1 .

... (RHOIN46s) that encodes a functional protein that cannot be ADP ribosylated to serve as a negative control; indeed, in such a strain (YOC724), the Rholp band was not observed (Fig. 4, lane 1). In cells expressing both the yeast RHOIN46s and human RHOA (YOC726), we found that levels of the RHOA prote ...
08-Inflammation and repair,hala
08-Inflammation and repair,hala

... by increased blood flow to the injured area, resulting mainly from arteriolar dilation and opening of capillary beds induced by mediators such as histamine. Increased vascular permeability results in the accumulation of protein-rich extravascular fluid, which forms the exudate. Plasma proteins leave ...
Structural and chemical differences in the cell wall regions in
Structural and chemical differences in the cell wall regions in

... that significant softening occurs in onion tissue during refrigerated storage.12 The composition of pectic polysaccharides may affect the texture of onion.10 Therefore it is possible that changes in firmness during storage could be affected by the activity of pectinases. Pectin methylesterase (PME) ...
Storage globulins pass through the Golgi apparatus and
Storage globulins pass through the Golgi apparatus and

... bodies (MVBs) in early stages of cotyledon development where neither dense vesicles (DVs) nor a PSV were recognizable. However, at later stages of cotyledon development, condensed globulins were visible in both DVs and distinct MVBs with a novel form of partitioning, with the internal vesicles being ...
Use of Phenylboronic Acids to Investigate Boron
Use of Phenylboronic Acids to Investigate Boron

... The only defined physiological role of boron in plants is as a cross-linking molecule involving reversible covalent bonds with cis-diols on either side of borate. Boronic acids, which form the same reversible bonds with cis-diols but cannot cross-link two molecules, were used to selectively disrupt ...
Evidence for land plant cell wall biosynthetic mechanisms in
Evidence for land plant cell wall biosynthetic mechanisms in

... enzyme-encoding genes responsible for their synthesis. Considerable research has focused on the investigation of cell wall structure and composition of terrestrial plants, in particular flowering plants. These studies underpin our current understanding that cell walls are fibre composite materials b ...
Autophagy and cell death in model organisms
Autophagy and cell death in model organisms

... programmed cell death (or apoptosis) is characterized by dependence on caspases, chromatin condensation and fragmentation and overall cell shrinkage. Blebbing of the plasma membrane leads to the formation of apoptotic bodies, which are ingested by phagocytes. Type 2 (or autophagic cell death) is cha ...
Autophagy and cell death in model organisms - IMBB
Autophagy and cell death in model organisms - IMBB

... programmed cell death (or apoptosis) is characterized by dependence on caspases, chromatin condensation and fragmentation and overall cell shrinkage. Blebbing of the plasma membrane leads to the formation of apoptotic bodies, which are ingested by phagocytes. Type 2 (or autophagic cell death) is cha ...
Lessons on longevity from budding yeast
Lessons on longevity from budding yeast

... The hypothesis that Sir2 activation accounts for RLS extension from dietary restriction has been controversial. Standard yeast medium contains 2% glucose, and the two most common methods of dietary restriction are to reduce glucose from 2% to either 0.5% (moderate dietary restriction) or 0.05% (extr ...
video slide
video slide

... Extracellular Matrix (ECM) of Animal Cells • Proteoglycan complexes and other macromolecules • Functions: – Support – Adhesion to other cells or surfaces – Movement – Regulation (influences binding of hormones or other factors to receptors on plasma membrane) ...
Wnt signaling: a common theme in animal development
Wnt signaling: a common theme in animal development

... DWnt-4 is too divergent to be assigned as an ortholog. ...
tubulin isotypes - Journal of Cell Science
tubulin isotypes - Journal of Cell Science

Title Soybean extracts increase cell surface ZIP4 abundance and
Title Soybean extracts increase cell surface ZIP4 abundance and

... increase ZIP4 could potentially enhance zinc absorption by the intestine. In this study, we used mouse Hepa cells, which regulate mouse Zip4 (mZip4) in a manner indistinguishable from that in intestinal enterocytes, to screen for suitable food components able to increase the abundance of ZIP4. Using ...
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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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