Histone H3 Phosphorylation Is Coupled to Poly-(ADP
... which they interact with cellular constituents, as well as the consequences of such interactions, are important fundamental goals of biomedical research. Renal proximal tubule epithelial cells are particularly sensitive to oxidant-mediated injury. Using a well-established in vitro model of renal pro ...
... which they interact with cellular constituents, as well as the consequences of such interactions, are important fundamental goals of biomedical research. Renal proximal tubule epithelial cells are particularly sensitive to oxidant-mediated injury. Using a well-established in vitro model of renal pro ...
Like-acetylglucosaminyltransferase (LARGE)
... our results demonstrate that the ligand-binding activity resides at the extreme N terminus of mature α-dystroglycan and is crucial for α-dystroglycan to coordinate the assembly of extracellular matrix proteins and to bind arenaviruses on the cell surface. ...
... our results demonstrate that the ligand-binding activity resides at the extreme N terminus of mature α-dystroglycan and is crucial for α-dystroglycan to coordinate the assembly of extracellular matrix proteins and to bind arenaviruses on the cell surface. ...
Adducin-1 is essential for mitotic spindle assembly through its
... are shown, which were from a single experiment out of three repeats (n > 160). (right) Graphs show the relative fluorescence intensity (F.I.) of the lines that were scanned by confocal microscopy. a.u., arbitrary unit. Bar, 5 µm. (B) The percentage of FLAG-ADD1 association with mitotic spindles in t ...
... are shown, which were from a single experiment out of three repeats (n > 160). (right) Graphs show the relative fluorescence intensity (F.I.) of the lines that were scanned by confocal microscopy. a.u., arbitrary unit. Bar, 5 µm. (B) The percentage of FLAG-ADD1 association with mitotic spindles in t ...
Aggresomes: A Cellular Response to Misfolded Proteins
... chains being able to mature beyond the ER. Newly synthesized CFTR and DF508 molecules that fail to fold productively are rapidly eliminated from cells by a process requiring covalent modification with ubiquitin and degradation by the proteasome (Jensen et al., 1995; Ward et al., 1995). Inhibition of ...
... chains being able to mature beyond the ER. Newly synthesized CFTR and DF508 molecules that fail to fold productively are rapidly eliminated from cells by a process requiring covalent modification with ubiquitin and degradation by the proteasome (Jensen et al., 1995; Ward et al., 1995). Inhibition of ...
The Heliothis Virescens Cadherin Protein Expressed in Drosophila
... medium (HyQ SFX-Insect, Hyclone) and transfected as previously described (23). Plasmid DNA used for transfections was prepared using a Plasmid Maxi Kit (Sigma). Approximately 2 × 106 S2 cells from a confluent culture were suspended in 5 mL of fresh medium and allowed to adhere to 60 mm × 15 mm polys ...
... medium (HyQ SFX-Insect, Hyclone) and transfected as previously described (23). Plasmid DNA used for transfections was prepared using a Plasmid Maxi Kit (Sigma). Approximately 2 × 106 S2 cells from a confluent culture were suspended in 5 mL of fresh medium and allowed to adhere to 60 mm × 15 mm polys ...
Cell Structure/Function
... 15. Plants are unable to move to a new location in response to changes in their environment. Which of the following organelles plays a role in maintaining homeostasis in a plant? Your Answer: ...
... 15. Plants are unable to move to a new location in response to changes in their environment. Which of the following organelles plays a role in maintaining homeostasis in a plant? Your Answer: ...
Animal Cell and Tissue Culture: From Basic Principles to Advanced
... P5: Preparation and observation of neurospheres cultures P6: Differentiation protocols and immunocytochemistry for the identification of neurons, astrocytes and oligodendrocytes ...
... P5: Preparation and observation of neurospheres cultures P6: Differentiation protocols and immunocytochemistry for the identification of neurons, astrocytes and oligodendrocytes ...
Cell polarity and tissue patterning in plants - Development
... An advantage of the "canalization hypothesis' is that it suggests various experimental approaches to cellular patterning (Sachs, 1981) and the one to be followed here is to search for additional cellular expressions of the same canalized controls of polarization. The 'canalization hypothesis' consid ...
... An advantage of the "canalization hypothesis' is that it suggests various experimental approaches to cellular patterning (Sachs, 1981) and the one to be followed here is to search for additional cellular expressions of the same canalized controls of polarization. The 'canalization hypothesis' consid ...
Selective Binding of the Scavenger Receptor C
... region encoding the dihydrofolate reductase gene (13). The resulting plasmid was transfected into DXB11 Chinese hamster ovary cells (which are deficient in dihydrofolate reductase) using the calcium phosphate method (14). Transfectants were selected by growth in minimal essential ␣ medium without nu ...
... region encoding the dihydrofolate reductase gene (13). The resulting plasmid was transfected into DXB11 Chinese hamster ovary cells (which are deficient in dihydrofolate reductase) using the calcium phosphate method (14). Transfectants were selected by growth in minimal essential ␣ medium without nu ...
how death shapes life during development
... autophagy seems to involve vacuolar proteolysis. During autophagic cell death, this proteolysis presumably serves to degrade the cell and plays the part of the phagocyte lysosome during apoptosis. Although autophagic vacuoles containing organelles such as mitochondria were observed in dying animal c ...
... autophagy seems to involve vacuolar proteolysis. During autophagic cell death, this proteolysis presumably serves to degrade the cell and plays the part of the phagocyte lysosome during apoptosis. Although autophagic vacuoles containing organelles such as mitochondria were observed in dying animal c ...
Tumor Microenvironment in Head and Neck Squamous Cell
... found low stromalsitotoksik CD8+ T-lymphocyte counts and a high number of stromal T regulatory cells to be associated with low survival, but they determined that the total number of T regulatory cells did not have an impact. Besides, it was revealed that the worst prognosis was in the group where th ...
... found low stromalsitotoksik CD8+ T-lymphocyte counts and a high number of stromal T regulatory cells to be associated with low survival, but they determined that the total number of T regulatory cells did not have an impact. Besides, it was revealed that the worst prognosis was in the group where th ...
CycD1, a Putative G1 Cyclin from Antirrhinum majus
... The Arath;CycD1;1 mutant plants have no obvious phenotype (O. Koroleva and J. Doonan, unpublished data). However, overexpression of selected D cyclin genes indicates that two of the three main groups have different functions. Thus, Arath;CycD2;1 appears to be rate limiting for progression through G1 ...
... The Arath;CycD1;1 mutant plants have no obvious phenotype (O. Koroleva and J. Doonan, unpublished data). However, overexpression of selected D cyclin genes indicates that two of the three main groups have different functions. Thus, Arath;CycD2;1 appears to be rate limiting for progression through G1 ...
Break of symmetry in regenerating tobacco protoplasts is
... Linda Brochhausen*, Jan Maisch and Peter Nick Molecular Cell Biology, Botanical Institute, Karlsruhe Institute of Technology, Kaiserstr. 2, D-76133 Karlsruhe, Germany. *Correspondence: Linda.Aimee@Brochhausen.com ...
... Linda Brochhausen*, Jan Maisch and Peter Nick Molecular Cell Biology, Botanical Institute, Karlsruhe Institute of Technology, Kaiserstr. 2, D-76133 Karlsruhe, Germany. *Correspondence: Linda.Aimee@Brochhausen.com ...
Bacillus globigii cell size is influenced by
... E. coli. In the MazEF system, the MazF toxin is a sequence-specific endoribonuclease (Zhang et al. 2003) and the MazE antitoxin an unstable dimeric protein which is sensitive to degradation by the ClpAP serine protease system (Aizenman et al. 1996). Both MazF and MazE form dimers, whereupon one MazE ...
... E. coli. In the MazEF system, the MazF toxin is a sequence-specific endoribonuclease (Zhang et al. 2003) and the MazE antitoxin an unstable dimeric protein which is sensitive to degradation by the ClpAP serine protease system (Aizenman et al. 1996). Both MazF and MazE form dimers, whereupon one MazE ...
interaction between tumor and immune system: the role of tumor cell
... discussed. The presented data show that it tumor cell biology that in many cases determines tumor antigen recognition and realization of cytotoxic action of killer cells. Here also we discuss own data obtained with the use of experimental tumor models (transplantable MC-rhabdomyosarcoma, B16 melanom ...
... discussed. The presented data show that it tumor cell biology that in many cases determines tumor antigen recognition and realization of cytotoxic action of killer cells. Here also we discuss own data obtained with the use of experimental tumor models (transplantable MC-rhabdomyosarcoma, B16 melanom ...
Stem cells in the light of evolution
... Regeneration has received renewed research interest in recent years. Stem cells have been extensively studied due to their regeneration potential. First, this property was shown by histologists in the 19th century who introduced an abstract term for cells which can specifically repair or regenerat ...
... Regeneration has received renewed research interest in recent years. Stem cells have been extensively studied due to their regeneration potential. First, this property was shown by histologists in the 19th century who introduced an abstract term for cells which can specifically repair or regenerat ...
CycD1, a Putative G1 Cyclin from Antirrhinum majus, Accelerates
... The Arath;CycD1;1 mutant plants have no obvious phenotype (O. Koroleva and J. Doonan, unpublished data). However, overexpression of selected D cyclin genes indicates that two of the three main groups have different functions. Thus, Arath;CycD2;1 appears to be rate limiting for progression through G1 ...
... The Arath;CycD1;1 mutant plants have no obvious phenotype (O. Koroleva and J. Doonan, unpublished data). However, overexpression of selected D cyclin genes indicates that two of the three main groups have different functions. Thus, Arath;CycD2;1 appears to be rate limiting for progression through G1 ...
An Introduction to the Reference Module in Life Sciences
... first are traditionally mainly treated by microbiologists whereas plant cells are purview of botanists, so here we mainly focus on the eukaryotic world, in particular on human cells, and limit the articles on other organisms to those that either are model organisms or are paradigmatic for various re ...
... first are traditionally mainly treated by microbiologists whereas plant cells are purview of botanists, so here we mainly focus on the eukaryotic world, in particular on human cells, and limit the articles on other organisms to those that either are model organisms or are paradigmatic for various re ...
Diel patterns of growth and division
... and Synechococcus (strains ALMO 03, ROS 04, WH 7803, and WH 8103) and five picoeukaryotes (Bathycoccus prasinos Eikrem et Throndsen, Bolidomonas pacifica Guillou et Chrétiennot-Dinet, Micromonas pusilla Manton et Parke, Pelagomonas calceolata Andersen et Saunders, and Pycnococcus provasolii Guillard ...
... and Synechococcus (strains ALMO 03, ROS 04, WH 7803, and WH 8103) and five picoeukaryotes (Bathycoccus prasinos Eikrem et Throndsen, Bolidomonas pacifica Guillou et Chrétiennot-Dinet, Micromonas pusilla Manton et Parke, Pelagomonas calceolata Andersen et Saunders, and Pycnococcus provasolii Guillard ...
Megf10 regulates the progression of the satellite cell myogenic
... factors such as Pax7 and Foxk1/myocite nuclear factor and cell surface markers such as c-Met/scatter factor receptor, syndecan 3 and 4, and M-cadherin, have been shown to be expressed in quiescent satellite cells, which allows for easy immunological identification (Holterman and Rudnicki, 2005). In ...
... factors such as Pax7 and Foxk1/myocite nuclear factor and cell surface markers such as c-Met/scatter factor receptor, syndecan 3 and 4, and M-cadherin, have been shown to be expressed in quiescent satellite cells, which allows for easy immunological identification (Holterman and Rudnicki, 2005). In ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).