Temporal and spatial mRNA expression of bone sialoprotein and
... point. The fibroblast-like cells of the PDL also expressed a lower level of both mRNAs. The fibroblasts in the PDL are more similar to osteoblasts than to fibroblasts in other tissues (Kawase et al., 1988). These similarities between fibroblasts and osteoblasts also exist in the PDL. Function of ost ...
... point. The fibroblast-like cells of the PDL also expressed a lower level of both mRNAs. The fibroblasts in the PDL are more similar to osteoblasts than to fibroblasts in other tissues (Kawase et al., 1988). These similarities between fibroblasts and osteoblasts also exist in the PDL. Function of ost ...
Roles of vaccinia virus EEV-specific proteins in intracellular actin tail
... syncytium formation after low pH shock was examined (Fig. 6). BS-C-1 cells infected with WR, ∆A34R or ∆A36R developed the usual cytopathic effect and did not fuse if incubated at pH 7 (Fig. 6 a–c). However, if these cultures were briefly exposed to pH 5, cells infected with WR and ∆A36R fused (Fig. ...
... syncytium formation after low pH shock was examined (Fig. 6). BS-C-1 cells infected with WR, ∆A34R or ∆A36R developed the usual cytopathic effect and did not fuse if incubated at pH 7 (Fig. 6 a–c). However, if these cultures were briefly exposed to pH 5, cells infected with WR and ∆A36R fused (Fig. ...
review cell division from a genetic perspective
... mentioned above has been shown to be defective in thymidylate synthetase (5). In some cases, however, the execution point for a particular mutant occurs considerably before the mutant cell exhibits any observable defect in its progress through the cell cycle. For example, mutants of S. cerevisiae we ...
... mentioned above has been shown to be defective in thymidylate synthetase (5). In some cases, however, the execution point for a particular mutant occurs considerably before the mutant cell exhibits any observable defect in its progress through the cell cycle. For example, mutants of S. cerevisiae we ...
Minus End-Directed Kinesin-Like Motor Protein
... undergo a profound transformation during mitosis. In Haemanthus endosperm, the metaphase spindle is predominantly barrel-shaped, but usually becomes convergent in anaphase [Smirnova and Bajer, 1994]. The change of spindle shape in anaphase is an important feature of mitosis, preventing formation of ...
... undergo a profound transformation during mitosis. In Haemanthus endosperm, the metaphase spindle is predominantly barrel-shaped, but usually becomes convergent in anaphase [Smirnova and Bajer, 1994]. The change of spindle shape in anaphase is an important feature of mitosis, preventing formation of ...
rapid communication - AJP
... 2001.—Mice lacking the 80-kDa CD2-associated protein (CD2AP) develop progressive renal failure that starts soon after birth with proteinuria and foot process effacement by unknown mechanisms. CD2AP has been identified and cloned independently by virtue of its interaction with the T cell protein CD2 ...
... 2001.—Mice lacking the 80-kDa CD2-associated protein (CD2AP) develop progressive renal failure that starts soon after birth with proteinuria and foot process effacement by unknown mechanisms. CD2AP has been identified and cloned independently by virtue of its interaction with the T cell protein CD2 ...
Dynamical patterning modules in plant development and evolution
... factors and other molecules through plasmodesmata (channels traversing cell walls and enabling transport and communication between cells), plays a central role during plant developmental processes (Kim and Zambryski, 2005). Although intercellular transport of developmental transcription factors is n ...
... factors and other molecules through plasmodesmata (channels traversing cell walls and enabling transport and communication between cells), plays a central role during plant developmental processes (Kim and Zambryski, 2005). Although intercellular transport of developmental transcription factors is n ...
Analyzing Red Blood Cell-Deformability Distributions
... J. G. G. Dobbe,1 M. R. Hardeman,2 G. J. Streekstra,3 J. Strackee,3 C. Ince,2 and C. A. Grimbergen1,3 ABSTRACT: Background. Red blood cells (RBCs) must deform to pass the smallest capillaries of the microcirculation. Available techniques for measuring RBC deformability often provide an indication of ...
... J. G. G. Dobbe,1 M. R. Hardeman,2 G. J. Streekstra,3 J. Strackee,3 C. Ince,2 and C. A. Grimbergen1,3 ABSTRACT: Background. Red blood cells (RBCs) must deform to pass the smallest capillaries of the microcirculation. Available techniques for measuring RBC deformability often provide an indication of ...
The syndapin protein family: linking membrane trafficking with the
... The formation and movement of vesicles, as well as the organization of different pools of vesicles within distinct compartments of cells, are thought to involve cytoskeletal elements; however, how the different molecular machineries involved are interconnected is mostly unclear (Qualmann et al., 200 ...
... The formation and movement of vesicles, as well as the organization of different pools of vesicles within distinct compartments of cells, are thought to involve cytoskeletal elements; however, how the different molecular machineries involved are interconnected is mostly unclear (Qualmann et al., 200 ...
functional differentiation of enterocytes in the follicle
... Tritiated valine at a concentration of 1 mM was presented to the luminal surface of rat mid-jejunum for a period of 45 s, as described in the previous section. A typical autoradiograph of sectioned tissue taken in the region of a Peyer's patch is shown in Fig. 1 A. Radioactivity is seen to be concen ...
... Tritiated valine at a concentration of 1 mM was presented to the luminal surface of rat mid-jejunum for a period of 45 s, as described in the previous section. A typical autoradiograph of sectioned tissue taken in the region of a Peyer's patch is shown in Fig. 1 A. Radioactivity is seen to be concen ...
Target Predictions using LINCS Data
... Specifically, the dataset contains experiments profiling the effects of 20,143 small-molecule compounds (including known drugs and pathway-specific tool compounds). In addition, there are 22,119 genetic constructs for over-expressing genes (gain-of-function) or knocking-down (KD) genes (lossof-funct ...
... Specifically, the dataset contains experiments profiling the effects of 20,143 small-molecule compounds (including known drugs and pathway-specific tool compounds). In addition, there are 22,119 genetic constructs for over-expressing genes (gain-of-function) or knocking-down (KD) genes (lossof-funct ...
Single-molecule super-resolution microscopy (STORM)
... myosin based intracellular transport, cell division, cell surface based movement and the ability of cells to adopt a variety of shapes. The actin cytoskeleton is made up of actin filaments decorated by a variety of actinbinding proteins. Actin-binding proteins play a fundamental role in the architec ...
... myosin based intracellular transport, cell division, cell surface based movement and the ability of cells to adopt a variety of shapes. The actin cytoskeleton is made up of actin filaments decorated by a variety of actinbinding proteins. Actin-binding proteins play a fundamental role in the architec ...
Regulatory role of rpL3 in cell response to nucleolar stress induced
... this aim, Calu-6 and HCT 116 p53-/- cells were transiently cotransfected with the full-length p21 promoter luciferase reporter plasmid and siRNA specific for rpL3 (rpL3-siRNA) or scrambled siRNA (Src-siRNA). Then, cells were treated with 5nM of Act D for 24 h or untreated and analyzed by western blot ...
... this aim, Calu-6 and HCT 116 p53-/- cells were transiently cotransfected with the full-length p21 promoter luciferase reporter plasmid and siRNA specific for rpL3 (rpL3-siRNA) or scrambled siRNA (Src-siRNA). Then, cells were treated with 5nM of Act D for 24 h or untreated and analyzed by western blot ...
Engineering Myocardial Tissue
... Two other, principally different tissue engineering approaches were developed in parallel. One originated from the material sciences field and can be viewed as an adaptation of “classical” tissue engineering principles36 to cardiac cells. One of the pioneering groups (VunjakNovakovic and colleagues ...
... Two other, principally different tissue engineering approaches were developed in parallel. One originated from the material sciences field and can be viewed as an adaptation of “classical” tissue engineering principles36 to cardiac cells. One of the pioneering groups (VunjakNovakovic and colleagues ...
The Connexin46 mutant (V44M)
... including gap junction channels to maintain lens homeostasis. Gap junctions in lens are mainly composed of three members of the connexins (Cx43, Cx46, and Cx50) as channel proteins. These channels facilitate intercellular communication between cells (Mathias et al. 2010). The intercellular communica ...
... including gap junction channels to maintain lens homeostasis. Gap junctions in lens are mainly composed of three members of the connexins (Cx43, Cx46, and Cx50) as channel proteins. These channels facilitate intercellular communication between cells (Mathias et al. 2010). The intercellular communica ...
Mesophyll structure during leaf development in Ballota acetabulosa
... Ballota acetabulosa is a common herbaceous, xerophytic species in south and east Greece (HeyThe regulation of COg transfer from the ambient air wood & Richardson, 1990). Adaptations of xerointo the leaf and concomitant loss of water from the phytes involve small and thick leaves, with high leaf is a ...
... Ballota acetabulosa is a common herbaceous, xerophytic species in south and east Greece (HeyThe regulation of COg transfer from the ambient air wood & Richardson, 1990). Adaptations of xerointo the leaf and concomitant loss of water from the phytes involve small and thick leaves, with high leaf is a ...
Length and Amino Acid Composition Complementarity
... Evidence is accumulating that the ⌯C is assessed for its ability to functionally associate with a LC before LC rearrangement, with the SLC functioning as the assessor (8, 11, 12). The presence of the SLC before LC rearrangement as well as its structural similarity to a conventional Ig LC make it an ...
... Evidence is accumulating that the ⌯C is assessed for its ability to functionally associate with a LC before LC rearrangement, with the SLC functioning as the assessor (8, 11, 12). The presence of the SLC before LC rearrangement as well as its structural similarity to a conventional Ig LC make it an ...
The Molecular Basis of Self-Avoidance
... Isoform-Specific Homophilic Recognition Dscam1 encodes a family of cell surface receptors, each of which comprises an ectodomain with 10 Ig domains, 6 fibronectin type III repeats, a transmembrane domain, and an intracellular C-terminal tail. Alternative splicing of three large blocks of alternative ...
... Isoform-Specific Homophilic Recognition Dscam1 encodes a family of cell surface receptors, each of which comprises an ectodomain with 10 Ig domains, 6 fibronectin type III repeats, a transmembrane domain, and an intracellular C-terminal tail. Alternative splicing of three large blocks of alternative ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).