Beta cell restoration
... into developing an antigenspecific T1D vaccine, may also be applicable in the restoration field. JDRF is seeking to accomplish something never before done in biomedical research: reverse an autoimmune attack and restore the body to normal function. Understandably, this will raise ...
... into developing an antigenspecific T1D vaccine, may also be applicable in the restoration field. JDRF is seeking to accomplish something never before done in biomedical research: reverse an autoimmune attack and restore the body to normal function. Understandably, this will raise ...
DLG5 in Cell Polarity Maintenance and Cancer Development
... like DLG1 and ZO1, DLG5 plays important roles in epithelial cell polarity maintenance, precursor cell division, cell proliferation, cell migration and invasion, and transmission of extracellular signals to the membrane and cytoskeleton. Numerous researchers have focused on the study of the roles of ...
... like DLG1 and ZO1, DLG5 plays important roles in epithelial cell polarity maintenance, precursor cell division, cell proliferation, cell migration and invasion, and transmission of extracellular signals to the membrane and cytoskeleton. Numerous researchers have focused on the study of the roles of ...
The VirE3 protein of Agrobacterium mimics a host cell function
... of GFP (YFP) is split into two parts, N-terminal (nYFP) and C-terminal (cYFP), neither of which fluoresces on its own. However, when nYFP and cYFP are brought together as fusions with interacting proteins, the fluorescence is restored (Hu et al, 2002). Here, we used BiFC in two different plant speci ...
... of GFP (YFP) is split into two parts, N-terminal (nYFP) and C-terminal (cYFP), neither of which fluoresces on its own. However, when nYFP and cYFP are brought together as fusions with interacting proteins, the fluorescence is restored (Hu et al, 2002). Here, we used BiFC in two different plant speci ...
The MHC I immunopeptidome conveys to the cell surface an
... et al, 2011). Therefore, further systematic studies based on high-throughput technologies and integrative approaches are needed in order to elucidate the mechanisms that mould the immunopeptidome. In-depth mechanistic understanding of the immunopeptidome biogenesis would allow prediction of its mole ...
... et al, 2011). Therefore, further systematic studies based on high-throughput technologies and integrative approaches are needed in order to elucidate the mechanisms that mould the immunopeptidome. In-depth mechanistic understanding of the immunopeptidome biogenesis would allow prediction of its mole ...
Final Draft
... A first investigation of C. capillata medusae regarding their neurotoxic activity was carried out by Lassen et al. (2010). They showed a blocking activity on voltage-gated sodium (Nav) channels expressed by mouse neuronal cells in partially purified fishing tentacle venom. Nav channels play an essen ...
... A first investigation of C. capillata medusae regarding their neurotoxic activity was carried out by Lassen et al. (2010). They showed a blocking activity on voltage-gated sodium (Nav) channels expressed by mouse neuronal cells in partially purified fishing tentacle venom. Nav channels play an essen ...
Liquid-Tissue Mechanics in Amphibian Gastrulation: Germ
... quite loosely, to other cells on all sides. By contrast, the outer faces of the surface cell populations appear to be shiny—"coated" in Holtfreter's terminology. We find, as he did (op. cit.), that the shiny sides of these surface cells are non-adhesive with respect to blastula and gastrula cells of ...
... quite loosely, to other cells on all sides. By contrast, the outer faces of the surface cell populations appear to be shiny—"coated" in Holtfreter's terminology. We find, as he did (op. cit.), that the shiny sides of these surface cells are non-adhesive with respect to blastula and gastrula cells of ...
Chapter 3
... • hyaluronic acid is thick, viscous and slippery • chondroitin sulfate is jellylike substance providing support • adhesion proteins (fibronectin) binds collagen fibers to ground substance ...
... • hyaluronic acid is thick, viscous and slippery • chondroitin sulfate is jellylike substance providing support • adhesion proteins (fibronectin) binds collagen fibers to ground substance ...
Chapter 3
... • hyaluronic acid is thick, viscous and slippery • chondroitin sulfate is jellylike substance providing support • adhesion proteins (fibronectin) binds collagen fibers to ground substance ...
... • hyaluronic acid is thick, viscous and slippery • chondroitin sulfate is jellylike substance providing support • adhesion proteins (fibronectin) binds collagen fibers to ground substance ...
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... Myeloperoxidase Deficiency – more common, defect in hyperchlorous acid (HOCl), usually clinically silent, although bacterial killing takes longer than norm Monocytes/Macrophages RES – the reticuloendothelial system is the monocyte/macrophage system Maturation – again involves proliferation, matu ...
... Myeloperoxidase Deficiency – more common, defect in hyperchlorous acid (HOCl), usually clinically silent, although bacterial killing takes longer than norm Monocytes/Macrophages RES – the reticuloendothelial system is the monocyte/macrophage system Maturation – again involves proliferation, matu ...
Epithelial differentiation and intercellular junction
... 1985; Levy et al., 1986). Cell contact signalling at the time of compaction appears to regulate the orientation and spatial features of polarisation in blastomeres that are already in a permissive state for this cue (Ziomek and Johnson, 1980; Johnson and Ziomek, 1981a). The cell contact signal is mo ...
... 1985; Levy et al., 1986). Cell contact signalling at the time of compaction appears to regulate the orientation and spatial features of polarisation in blastomeres that are already in a permissive state for this cue (Ziomek and Johnson, 1980; Johnson and Ziomek, 1981a). The cell contact signal is mo ...
Epithelia and Connective Tissue
... display more than one epithelium and more than one connective tissue type. Skin and GI tract are particularly useful to examine because of the variety of tissues and epithelium present. This laboratory exercise is about identifying 9 different epithelia and 5 different connective tissues. Try to exa ...
... display more than one epithelium and more than one connective tissue type. Skin and GI tract are particularly useful to examine because of the variety of tissues and epithelium present. This laboratory exercise is about identifying 9 different epithelia and 5 different connective tissues. Try to exa ...
Development of secretory cells and crystal cells in Eichhornia
... secretory cells are related to the secretion products. For examples, the secretion products of floral nectars contain sugar, which can attract insects to visit and pollinate the flowers. Mastroberti and Mariath (2008) suggested that a role of the secretory cells (also called mucilage cells) in young ...
... secretory cells are related to the secretion products. For examples, the secretion products of floral nectars contain sugar, which can attract insects to visit and pollinate the flowers. Mastroberti and Mariath (2008) suggested that a role of the secretory cells (also called mucilage cells) in young ...
Herpesvirus Glycoproteins Undergo Multiple Antigenic Changes
... G (VSV-G) [2,3]. gH/gL does not appear to be a typical fusogen [4], but has a conserved hydrophobic patch that could participate in fusion [5]. An additional virion glycoprotein often regulates gH/gL/gB. For example the Herpes simplex virus (HSV) gD brings together gH/gL and gB in transfected cells ...
... G (VSV-G) [2,3]. gH/gL does not appear to be a typical fusogen [4], but has a conserved hydrophobic patch that could participate in fusion [5]. An additional virion glycoprotein often regulates gH/gL/gB. For example the Herpes simplex virus (HSV) gD brings together gH/gL and gB in transfected cells ...
Genetic Regulation of Embryonic Pattern Formation
... Several observations suggest that the two parental gene copies contribute differentially to early plant embryogenesis as a result of parent-specific imprinting. For example, heterozygosity for mutations in the MEDEA (MEA) gene results in 50% aborted embryos that cannot be rescued by one or even two ...
... Several observations suggest that the two parental gene copies contribute differentially to early plant embryogenesis as a result of parent-specific imprinting. For example, heterozygosity for mutations in the MEDEA (MEA) gene results in 50% aborted embryos that cannot be rescued by one or even two ...
Cells 1.2
... • The Golgi apparatus gathers simple molecules and combines them to make molecules that are more complex. • It then takes those big molecules, packages them in vesicles, and either stores them for later use or sends them out of the cell. • It is also the organelle that builds lysosomes (cell ...
... • The Golgi apparatus gathers simple molecules and combines them to make molecules that are more complex. • It then takes those big molecules, packages them in vesicles, and either stores them for later use or sends them out of the cell. • It is also the organelle that builds lysosomes (cell ...
Higher-order chromatin structure: looping long molecules
... the answer to all these questions is a carefully qualified ‘yes’. However, these questions have not been answered sequentially or independently but, rather, as an understanding develops on one front, aspects of another fall into place, and previously unrelated features connect by extrapolation from ...
... the answer to all these questions is a carefully qualified ‘yes’. However, these questions have not been answered sequentially or independently but, rather, as an understanding develops on one front, aspects of another fall into place, and previously unrelated features connect by extrapolation from ...
Wnt Signaling Translocates Lys48-Linked
... et al., 2014), and lysed in the presence of Triton X-100 and 1% SDS to solubilize MVBs. Immunoprecipitation studies showed that the polyubiquitinated fractions of GFP-b-catenin (Figure 2K), FLAG-Smad1 (Figure 2L), and FLAG-Smad4 (Figure 2M) were indeed stabilized by Wnt3a treatment for 2–4 hr in the ...
... et al., 2014), and lysed in the presence of Triton X-100 and 1% SDS to solubilize MVBs. Immunoprecipitation studies showed that the polyubiquitinated fractions of GFP-b-catenin (Figure 2K), FLAG-Smad1 (Figure 2L), and FLAG-Smad4 (Figure 2M) were indeed stabilized by Wnt3a treatment for 2–4 hr in the ...
Human CHMP6, a myristoylated ESCRT-III protein, interacts directly
... often oriented closer to the nucleus. An MVB (multivesicular body) is defined as an endosome that contains a characteristic accumulation of vesicles in its lumen, as shown by morphological observation, and such bodies are often seen in late endosomes ...
... often oriented closer to the nucleus. An MVB (multivesicular body) is defined as an endosome that contains a characteristic accumulation of vesicles in its lumen, as shown by morphological observation, and such bodies are often seen in late endosomes ...
PDF
... A transcription factor network that is stabilized by positive and negative regulation between its components is a good mechanism for maintaining the stable gene expression patterns that determine a particular cell phenotype (von Dassow et al., 2000). Moreover, the application of systems biological v ...
... A transcription factor network that is stabilized by positive and negative regulation between its components is a good mechanism for maintaining the stable gene expression patterns that determine a particular cell phenotype (von Dassow et al., 2000). Moreover, the application of systems biological v ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).