Prescribing Information for BiDil
... A meta-analysis of randomized controlled trials comparing hydralazine hydrochloride with other antihypertensive agents for severe hypertension in pregnancy found that hydralazine hydrochloride was associated with significantly more maternal hypotension, placental abruption, caesarean sections and ol ...
... A meta-analysis of randomized controlled trials comparing hydralazine hydrochloride with other antihypertensive agents for severe hypertension in pregnancy found that hydralazine hydrochloride was associated with significantly more maternal hypotension, placental abruption, caesarean sections and ol ...
Morphine - Waitemata District Health Board
... ladder3. It is appropriate for patients with moderate to severe pain which is opioid responsive. Before prescribing morphine, a patient must have a pain assessment and the likely cause of pain determined so that the most effective management can be implemented. Not all pain responds to opioids. Gene ...
... ladder3. It is appropriate for patients with moderate to severe pain which is opioid responsive. Before prescribing morphine, a patient must have a pain assessment and the likely cause of pain determined so that the most effective management can be implemented. Not all pain responds to opioids. Gene ...
Topamax SPC
... Digoxin: In a single-dose study, serum digoxin area under plasma concentration curve (AUC) decreased 12% due to concomitant administration of Topamax. The clinical relevance of this observation has not been established. When Topamax is added or withdrawn in patients on digoxin therapy, careful atten ...
... Digoxin: In a single-dose study, serum digoxin area under plasma concentration curve (AUC) decreased 12% due to concomitant administration of Topamax. The clinical relevance of this observation has not been established. When Topamax is added or withdrawn in patients on digoxin therapy, careful atten ...
Valtrex - GlaxoSmithKline
... valacyclovir and acyclovir during late pregnancy, the steady-state daily acyclovir AUC (area under plasma concentration-time curve) following valacyclovir 1000 mg was approximately 2 times greater than that observed with oral acyclovir at 1200 mg daily. VALTREX® caplets should be used during pregnan ...
... valacyclovir and acyclovir during late pregnancy, the steady-state daily acyclovir AUC (area under plasma concentration-time curve) following valacyclovir 1000 mg was approximately 2 times greater than that observed with oral acyclovir at 1200 mg daily. VALTREX® caplets should be used during pregnan ...
Product Monograph
... As with other NSAIDs, borderline elevations of one or more liver enzyme tests (AST, ALT, alkaline phosphatase) may occur in up to 15% of patients. These abnormalities may progress, may remain essentially unchanged, or may be transient with continued therapy. Chronic alcoholic liver disease and proba ...
... As with other NSAIDs, borderline elevations of one or more liver enzyme tests (AST, ALT, alkaline phosphatase) may occur in up to 15% of patients. These abnormalities may progress, may remain essentially unchanged, or may be transient with continued therapy. Chronic alcoholic liver disease and proba ...
Module III
... Opioid Addiction A synthetic opioid Described as a mixed opioid agonistantagonist (or partial agonist) Available for use by certified physicians outside traditionally licensed opioid treatment programs ...
... Opioid Addiction A synthetic opioid Described as a mixed opioid agonistantagonist (or partial agonist) Available for use by certified physicians outside traditionally licensed opioid treatment programs ...
Hydrocodone Bitartrate
... moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bitartrate is available in the United States only in fixed combinations with non-opiate drugs (e.g., acetamin ...
... moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bitartrate is available in the United States only in fixed combinations with non-opiate drugs (e.g., acetamin ...
Pharmacology
... Note: some advocate combination of ACEI and ARB Renal / DM / HTN / (and probably any form of) proteinuria renoprotective by at least 2 mechanisms reduction of glomerular pressure (by relaxing efferent constriction) blocking action and local formation of TGF-B1 (which causes mesangial proliferati ...
... Note: some advocate combination of ACEI and ARB Renal / DM / HTN / (and probably any form of) proteinuria renoprotective by at least 2 mechanisms reduction of glomerular pressure (by relaxing efferent constriction) blocking action and local formation of TGF-B1 (which causes mesangial proliferati ...
Systemic Therapy for Rosacea
... inflammatory response, is believed to be the rationale for its effectiveness in treating rosacea.5 Tetracyclines are highly effective for papulopustular rosacea, requiring only 3-4 weeks of treatment for substantial improvement. Tetracycline 250-1000mg q.d., doxycycline 100-200mg q.d., and minocycli ...
... inflammatory response, is believed to be the rationale for its effectiveness in treating rosacea.5 Tetracyclines are highly effective for papulopustular rosacea, requiring only 3-4 weeks of treatment for substantial improvement. Tetracycline 250-1000mg q.d., doxycycline 100-200mg q.d., and minocycli ...
Update on Azole Antifungals
... Cryptococcus neoformans, Blastomyces dermatitidis, Coccidioides spp., Histoplasma capsulatum, Sporothrix schenckii, and ringworm. It is first-choice treatment for certain Candida and cryptococcal infections as well as nonmeningeal coccidioidal infections. Fluconazole as a single dose of 150 mg is ef ...
... Cryptococcus neoformans, Blastomyces dermatitidis, Coccidioides spp., Histoplasma capsulatum, Sporothrix schenckii, and ringworm. It is first-choice treatment for certain Candida and cryptococcal infections as well as nonmeningeal coccidioidal infections. Fluconazole as a single dose of 150 mg is ef ...
SUMMARY OF PRODUCT CHARACTERISTICS
... Fertility studies to assess the reproductive toxicity of cytarabine have not been conducted. Gonadal suppression, resulting in amenorrhea or azoospermia, may occur in patient taking cytarabine therapy, especially in combination with the alkylating agents. In general, these effects appear to be relat ...
... Fertility studies to assess the reproductive toxicity of cytarabine have not been conducted. Gonadal suppression, resulting in amenorrhea or azoospermia, may occur in patient taking cytarabine therapy, especially in combination with the alkylating agents. In general, these effects appear to be relat ...
Macrolids
... isolate is susceptible), streptococci, or pneumococci. Emergence of erythromycin resistance in strains of group A streptococci and pneumococci (penicillin-resistant pneumococci in particular) has made macrolides less attractive as first-line agents for treatment of pharyngitis, skin and soft tissue ...
... isolate is susceptible), streptococci, or pneumococci. Emergence of erythromycin resistance in strains of group A streptococci and pneumococci (penicillin-resistant pneumococci in particular) has made macrolides less attractive as first-line agents for treatment of pharyngitis, skin and soft tissue ...
Anabolic steroid-induced hypogonadism – Towards a unified
... ure to AAS, with the signs and symptoms after AAS cessation indications of AAS withdrawal [33–37]. Upon nonprescription AAS cessation, psychological disturbances include aggressiveness, depression, anxiousness, potency problems (libido), sleep disorders, violent behavior, rage, and suicidal ideation ...
... ure to AAS, with the signs and symptoms after AAS cessation indications of AAS withdrawal [33–37]. Upon nonprescription AAS cessation, psychological disturbances include aggressiveness, depression, anxiousness, potency problems (libido), sleep disorders, violent behavior, rage, and suicidal ideation ...
DRUG ABSORPTION BY SUBLINGUAL AND RECTAL ROUTES
... FIG. 2. Plasma concentrations of lignocaine following 200mgi.v. (Q), 300 mg rectal ( • ) and 300 mg oral (O) administration to subject G.M. (After De Boer et al., 1979; reproduced with permission.) ...
... FIG. 2. Plasma concentrations of lignocaine following 200mgi.v. (Q), 300 mg rectal ( • ) and 300 mg oral (O) administration to subject G.M. (After De Boer et al., 1979; reproduced with permission.) ...
Imitrex - GlaxoSmithKline
... symptoms have been identified as being the likely result of coronary vasospasm or myocardial ischemia. Rare cases of serious coronary events or arrhythmia have occurred following use of IMITREX®. IMITREX DF® and IMITREX® should not be given to patients who have documented ischemic or vasospastic cor ...
... symptoms have been identified as being the likely result of coronary vasospasm or myocardial ischemia. Rare cases of serious coronary events or arrhythmia have occurred following use of IMITREX®. IMITREX DF® and IMITREX® should not be given to patients who have documented ischemic or vasospastic cor ...
for meta-analysis
... 1. Atherosclerosis, and its attendant complication of thrombosis (atherothrombosis), is the leading cause of cardiovascular mortality and morbidity 2. Antiplatelet therapy post percutaneous coronary intervention (PCI) is a must 3. Aspirin is imperfect, relatively weak (COX-1 inhibitor), and associat ...
... 1. Atherosclerosis, and its attendant complication of thrombosis (atherothrombosis), is the leading cause of cardiovascular mortality and morbidity 2. Antiplatelet therapy post percutaneous coronary intervention (PCI) is a must 3. Aspirin is imperfect, relatively weak (COX-1 inhibitor), and associat ...
Pyridoxine hydrochloride attenuate and decrease the depressant
... Therefore; pyridoxine HCl showed in close proximity ...
... Therefore; pyridoxine HCl showed in close proximity ...
\\Appganim\Fda\Mt\Alonim\1921.doc PRAMIN INJECTION TABLETS
... There is some evidence that metoclopramide may cause depressive episodes. Decreasing the dose to enable resolution of depression, then increasing the dose gradually may obviate depressive symptoms. Metoclopramide should be given to patients with a prior history of depression only if the expected ben ...
... There is some evidence that metoclopramide may cause depressive episodes. Decreasing the dose to enable resolution of depression, then increasing the dose gradually may obviate depressive symptoms. Metoclopramide should be given to patients with a prior history of depression only if the expected ben ...
Metronidazole - American Academy of Veterinary Pharmacology
... fetal circulation.{R-1} No teratogenic effects were seen in the pups of rats that had received 250 mg per kg of body weight (mg/kg) a day for 1 to 12 days, or 100 mg/kg a day for 40 days. However, spermatogenesis in male rats was affected by the administration of 100 mg/kg a day. ...
... fetal circulation.{R-1} No teratogenic effects were seen in the pups of rats that had received 250 mg per kg of body weight (mg/kg) a day for 1 to 12 days, or 100 mg/kg a day for 40 days. However, spermatogenesis in male rats was affected by the administration of 100 mg/kg a day. ...
Acyclovir Tablets USP Acyclovir Tablets USP
... nephrotoxic agents since this may increase the risk of renal dysfunction and/or the risk of reversible central nervous system symptoms such as those that have been reported in patients treated with intravenous acyclovir. Adequate hydration should be maintained. ...
... nephrotoxic agents since this may increase the risk of renal dysfunction and/or the risk of reversible central nervous system symptoms such as those that have been reported in patients treated with intravenous acyclovir. Adequate hydration should be maintained. ...
Pain Anticoagulation Guidelines
... Aspirin’s (acetylsalicylic acid) Effects on Hemostasis Aspirin is rapidly absorbed from the gastrointestinal tract with peak levels occurring approximately 30 to 40 minutes following ingestion, resulting in platelet inhibition at one hour.37,38 The peak plasma levels for enteric-coated aspirin may b ...
... Aspirin’s (acetylsalicylic acid) Effects on Hemostasis Aspirin is rapidly absorbed from the gastrointestinal tract with peak levels occurring approximately 30 to 40 minutes following ingestion, resulting in platelet inhibition at one hour.37,38 The peak plasma levels for enteric-coated aspirin may b ...
Mark Jansen, M.D.
... Topical may be irritating. Prolonged use may predispose to fungal or bacterial superinfections including C. difficile. Warn to notify if patient develops diarrhea or bloody stool. Less likely than with oral form ...
... Topical may be irritating. Prolonged use may predispose to fungal or bacterial superinfections including C. difficile. Warn to notify if patient develops diarrhea or bloody stool. Less likely than with oral form ...
Thiazide and Thiazide
... • It is primarily used to treat congestive hear failure and HTN • Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart f ...
... • It is primarily used to treat congestive hear failure and HTN • Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart f ...
Fentanyl Buccal Lozenges (Actiq®)
... fentanyl buccal film dose has been determined, the patient should receive a prescription for the effective dosage strength and use or dispose of the remaining unused 200 mcg films. Fentanyl buccal films should not be torn or cut prior to use and will dissolve within 15 to 30 minutes following applic ...
... fentanyl buccal film dose has been determined, the patient should receive a prescription for the effective dosage strength and use or dispose of the remaining unused 200 mcg films. Fentanyl buccal films should not be torn or cut prior to use and will dissolve within 15 to 30 minutes following applic ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.