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cholesterol and lipo..
cholesterol and lipo..

... Cholesterol synthesis (structures not required) cytoplasmic H MG-CoA synthase (different from that responsible for ketogenesis) ...
8 BOWEL CANCER AND INHERITED PREDISPOSITION—Cancer
8 BOWEL CANCER AND INHERITED PREDISPOSITION—Cancer

... Everyone is born with two copies of an APC gene. Most people are born with two working copies of their APC gene; a few people are born with a working copy and a faulty copy of their APC gene. About one third of people with FAP have no known family history of the condition. There are two possible exp ...
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14_chapter 4

... genetic, taxon, and ecosystem levels (McNeely et al., 1990). Importance of biodiversity in this era of global climate change is recognized and hence United Nations declared 2010 as the International year of biodiversity. India is recognized as one of the 12 mega diversity regions of the world for it ...
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Iron mediated methylthiolation of tRNA as a regulator of operon

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Tetrahymena Contain Two Distinct and Unusual High Mobility Group

phenotype describes a new mutation affecting
phenotype describes a new mutation affecting

... maturity, characterized by an increase in size, synthesis of seed storage products and the acquisition of a dormant state preventing precocious germination (Sheridan and Clark, 1987). Abscisic acid (ABA) plays an important role during the maturation stage of embryogenesis. For example, it prevents p ...
Identifying the genomic determinants of aging and longevity in
Identifying the genomic determinants of aging and longevity in

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... other mitochondrial uncoupling proteins) which are activated by calcium coming in through the calcium uniporter. Also note that electron carriers can autooxidize directly to oxygen, creating oxygen radicals (Co-Q is the major site of autooxidation) with as much as 5% of resting oxygen use due to thi ...
Protein for Athletes
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View PDF - OSU Biochemistry and Molecular Biology
View PDF - OSU Biochemistry and Molecular Biology

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... The genes reside in a long molecule called deoxyribonucleic acid (DN'A). The DNA, in conjunction with a protein matrix, forms nucleoprotein and becomes organized into structures with distinctive staining properties called chromosomes found in the nucleus of the cell. The behavior of genes is thus pa ...
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Gene Section CYP2A6 (cytochrome P450, family 2, subfamily A, polypeptide 6)

... CYP2A6 shows large interindividual and interethnic variations in its expression levels and conversion activities, which are mainly attributed to CYP2A6 genetic polymorphisms. These alleles are derived from single nucleotide polymorphisms in the regulatory and coding regions, deletion mutations and c ...
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Genetics Questions - G. Holmes Braddock

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Modifying effects of phenotypic plasticity on interactions among

... once induced by an environmental cue becomes canalized, so that it is expressed even when the environmental cue is removed (reviewed by West-Eberhard, 2003; Crispo, 2007). Plasticity could be lost due to neutral processes (i.e. drift) if populations are located in homogeneous environments (i.e. plas ...
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... chiasmate bivalents. If sister chromatids were nondisjoining, we would have recovered progeny homozygous for centromere proximal markers like pr or cn, and these were not found. These data show that, like the X chromosome, autosomal nondisjunction in a mei-38 female occurs predominantly at meiosis I ...
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How cohesin and CTCF cooperate in regulating gene expression

... of these ‘CTCF only’ sites was analyzed by quantitative polymerase chain reactions (qPCR) of ChIP samples, cohesin could also be detected at these sites. Many of the ‘CTCF only’ sites may therefore also be bound by cohesin. CTCF sites have also been identified in a number of other studies (see below ...
Molecular Identification of Nematodes Manual
Molecular Identification of Nematodes Manual

... to their specific “binding sites.” We use this particular form of PCR where two primers are used in the reaction. They were specifically designed from a DNA template sequence (previously obtained from the literature or personal DNA sequencing) to be complimentary to that specific sequence, they are ...
Genetics - York University
Genetics - York University

... How was evolution possible if Mendel’ Mendel’s conception was correct? Darwin required that subsequent generations of a species exhibit a set of characteristics that varied, but around a different center. • Answer: Mutations. ...
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... Fig. 2. Disruption of the PbATPβ gene locus to generate the PbATPβKO line, which lacks PbATPβ protein production. (A) The plasmid pL-βKO with a selectable marker (hDHFR) flanked by 5′ and 3′ integration sequences amplified from the PbATPβ gene locus (5′ and 3′ black boxes) undergoes double cross-ove ...
Direct control of shoot meristem activity by a cytokinin
Direct control of shoot meristem activity by a cytokinin

... decarboxylation of L-lysine to generate cadaverine, a kind of polyamine (http://rapdb.dna.affrc.go.jp/). However, we were not able to detect lysine decarboxylase activity with purified recombinant LOG protein (data not shown). Genes homologous to LOG are found in a wide range of organisms including ...
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An Update on the Hereditary Spastic Paraplegias: New Genes and

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Maintenance of genomic integrity by p53: complementary

... preventing ®xation of DNA damage as mutations. This function of p53 led to the now famous coining of p53 as the `guardian of the genome' by Lane (1992). Although the main features of p53's role in maintaining the integrity of the genome seem to be outlined, there is still a lot to be learned as to h ...
Molecular Cloning of Dog Mast Cell Tryptase and a Related Protease
Molecular Cloning of Dog Mast Cell Tryptase and a Related Protease

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Analytical approaches to RNA profiling data for

... hybridization(ISH) data from the Allen Brain Atlas (ABA)(11). Since it is often difficult to establish cell identity by ISH data alone, we chose for this first comparative study four cell types that are relatively simple to identify by size and localization in colormetric ISH (brainstem motor neuron ...
review article
review article

... including those of biological warfare, quorum sensing, intercellular signalling and regulation of gene expression. It is therefore not surprising that several transporter families have evolved to control and facilitate exchange of these substances between cells and their environment, between cells a ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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