Genetic Architecture of Maize Kernel Composition in the Nested
... (NAM) population (McMullen et al., 2009) and the 282 inbred line association panel (FlintGarcia et al., 2005) were developed for high-power, high-resolution QTL analysis. The NAM population was developed by crossing 25 diverse founder inbred lines to the reference inbred B73, and producing 25 recomb ...
... (NAM) population (McMullen et al., 2009) and the 282 inbred line association panel (FlintGarcia et al., 2005) were developed for high-power, high-resolution QTL analysis. The NAM population was developed by crossing 25 diverse founder inbred lines to the reference inbred B73, and producing 25 recomb ...
Twinning and Embryonic Left-Right Asymmetry
... body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exhibits when viewed from the outside. Interestingly though, the internal organs of most animals reveal an individually and evolutionarily conserved asymme ...
... body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exhibits when viewed from the outside. Interestingly though, the internal organs of most animals reveal an individually and evolutionarily conserved asymme ...
Improvement of Aspergillus nidulans penicillin production by
... Aspergillus nidulans is able to synthesize penicillin and serves as a model to study the regulation of its biosynthesis. Only three enzymes are required to form the beta lactam ring tripeptide, which is comprised of L-cysteine, L-valine and L-aminoadipic acid. Whereas two enzymes, AcvA and IpnA loca ...
... Aspergillus nidulans is able to synthesize penicillin and serves as a model to study the regulation of its biosynthesis. Only three enzymes are required to form the beta lactam ring tripeptide, which is comprised of L-cysteine, L-valine and L-aminoadipic acid. Whereas two enzymes, AcvA and IpnA loca ...
The Biology of Aging
... • Mutations can accelerate or delay aging • Pathways that control aging are conserved across 1 billion years of evolution • Drugs that target these pathways may someday be used to treat diseases of aging and extend life ...
... • Mutations can accelerate or delay aging • Pathways that control aging are conserved across 1 billion years of evolution • Drugs that target these pathways may someday be used to treat diseases of aging and extend life ...
PPT - Altogen Biosystems
... 3. Prepare transfection complexes by mixing 40 µl of serum-free medium, 5.5 µl of transfection reagent, and • 750 ng DNA (or mRNA), or • 30 nM - 50 nM of siRNA (or microRNA) *Referred to a final volume including growth medium 4. Incubate transfection complexes at RT for 15 - 30 minutes 5. Optional: ...
... 3. Prepare transfection complexes by mixing 40 µl of serum-free medium, 5.5 µl of transfection reagent, and • 750 ng DNA (or mRNA), or • 30 nM - 50 nM of siRNA (or microRNA) *Referred to a final volume including growth medium 4. Incubate transfection complexes at RT for 15 - 30 minutes 5. Optional: ...
Unbalanced Translocation Breakout
... • Missing genetic material (5p deletion) and added genetic material (partial duplication of another chromosome). • The amount of protein synthesized is often proportional to the number of gene copies present • Extra genes can lead to excess protein and deletions can also affect gene dosage ...
... • Missing genetic material (5p deletion) and added genetic material (partial duplication of another chromosome). • The amount of protein synthesized is often proportional to the number of gene copies present • Extra genes can lead to excess protein and deletions can also affect gene dosage ...
Ana Maria da Silva Esteves Dissertation presented to obtain
... better suited for osmoprotection. This is one more illustration of solute replacement, a strategy generally used by organisms that rely on solute accumulation for osmoregulation. The patterns of compatible solute accumulation by Pyrococcus furiosus in response to heat stress are known, but the effec ...
... better suited for osmoprotection. This is one more illustration of solute replacement, a strategy generally used by organisms that rely on solute accumulation for osmoregulation. The patterns of compatible solute accumulation by Pyrococcus furiosus in response to heat stress are known, but the effec ...
Hereditary hemorrhagic telangiectasia: genetics and molecular
... 85% of cases submitted to clinical molecular genetics laboratories for clinical suspicion of HHT. Over 750 pathogenic ENG and ACVRL1 mutations have been described to date (HHT mutation databases1, 2 ). The HHT mutation database3 is the most comprehensive database for endoglin and ACVRL1 mutations de ...
... 85% of cases submitted to clinical molecular genetics laboratories for clinical suspicion of HHT. Over 750 pathogenic ENG and ACVRL1 mutations have been described to date (HHT mutation databases1, 2 ). The HHT mutation database3 is the most comprehensive database for endoglin and ACVRL1 mutations de ...
Pultz, M. A., and Baker, B. S.
... effects. We have also taken advantage of the herl(2)mat allele (Redfield, 1926), which is severely defective in maternal her functions but comparable to wild-type in zygotic her functions (Pultz et al., 1994). Maternal effects of her on female viability The maternal function of her is needed for the ...
... effects. We have also taken advantage of the herl(2)mat allele (Redfield, 1926), which is severely defective in maternal her functions but comparable to wild-type in zygotic her functions (Pultz et al., 1994). Maternal effects of her on female viability The maternal function of her is needed for the ...
BT314 Virology
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
University of Groningen Mutants and homologs of
... active site residues of E. coli PGA increased the fraction of the new acyl side chain that is coupled to the β-lactam nucleus (i.e. the synthesis to hydrolysis ratio Vs/Vh), thereby increasing the yield of ampicillin and cephalexin synthesis two to four-fold [96]. In a different approach, the Vs/Vh ...
... active site residues of E. coli PGA increased the fraction of the new acyl side chain that is coupled to the β-lactam nucleus (i.e. the synthesis to hydrolysis ratio Vs/Vh), thereby increasing the yield of ampicillin and cephalexin synthesis two to four-fold [96]. In a different approach, the Vs/Vh ...
Nanotechnology for the Delivery of Therapeutic Nucleic Acids
... function. Despite the promise, developing any NA as therapeutics has proven challenging. Like most drug development, there is no quick fix. Although many of the hurdles to developing NA-based drugs have been easily addressed, the main obstacle is figuring out how to deliver these molecules into cell ...
... function. Despite the promise, developing any NA as therapeutics has proven challenging. Like most drug development, there is no quick fix. Although many of the hurdles to developing NA-based drugs have been easily addressed, the main obstacle is figuring out how to deliver these molecules into cell ...
Introduction to Genetics
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
... preceding biology course. We begin by considering the importance of genetics to each of us, to society at large, and to students of biology. We then turn to the history of genetics, how the field as a whole developed. The final part of the chapter reviews some fundamental terms and principles of gen ...
Complex cocktails: the evolutionary novelty of venoms
... supplement the venom immunization mixture. An alternative genebased approach to developing toxin-specific antivenom has also been pioneered [83,84], which utilizes gene sequence data to distinguish venom toxins from nontoxins [85,86] and bioinformatic tools to identify regions (epitopes) common to r ...
... supplement the venom immunization mixture. An alternative genebased approach to developing toxin-specific antivenom has also been pioneered [83,84], which utilizes gene sequence data to distinguish venom toxins from nontoxins [85,86] and bioinformatic tools to identify regions (epitopes) common to r ...
Imprinting of the Y Chromosome Influences Dosage Compensation
... C(1)DX y1f1; [w14D4.3] females. To obtain males with maternal and paternal roX1 roX2 chromosomes from the same mothers, roX1ex6 roX2/Df(1)nod FM7a; [w14D4.3]/1 females were generated. These females have nonexchange X chromosomes, lack nod, and display .50% nondisjunction of their X chromosomes, cons ...
... C(1)DX y1f1; [w14D4.3] females. To obtain males with maternal and paternal roX1 roX2 chromosomes from the same mothers, roX1ex6 roX2/Df(1)nod FM7a; [w14D4.3]/1 females were generated. These females have nonexchange X chromosomes, lack nod, and display .50% nondisjunction of their X chromosomes, cons ...
Introduction to Carbohydrates
... B. Synthesis of bile acids • Bile acids are synthesized in the liver by a multistep, multiorganelle pathway in which hydroxyl groups are inserted at specific positions on the steroid structure, the double bond of the cholesterol B ring is reduced, and the hydrocarbon chain is shortened by three car ...
... B. Synthesis of bile acids • Bile acids are synthesized in the liver by a multistep, multiorganelle pathway in which hydroxyl groups are inserted at specific positions on the steroid structure, the double bond of the cholesterol B ring is reduced, and the hydrocarbon chain is shortened by three car ...
The zebrafish as a model for muscular dystrophy and congenital
... a transmembrane link between the cytoskeleton and the extracellular matrix. This complex also acts as an anchor for certain signalling components such as nitric oxide synthase (4–6). The complex consists of several sub-complexes of a few proteins, with the main structural axis being provided by a se ...
... a transmembrane link between the cytoskeleton and the extracellular matrix. This complex also acts as an anchor for certain signalling components such as nitric oxide synthase (4–6). The complex consists of several sub-complexes of a few proteins, with the main structural axis being provided by a se ...
View/Open - VUW research archive - Victoria University of Wellington
... Bede Busby, Peter Birchirm, Katie Zeier, and Dr Christine Stockholm. Thank you for sharing your time and friendship. Lastly, to my family, you have been such a great support group. Thank you all so much!!! ...
... Bede Busby, Peter Birchirm, Katie Zeier, and Dr Christine Stockholm. Thank you for sharing your time and friendship. Lastly, to my family, you have been such a great support group. Thank you all so much!!! ...
DESIGN, SYNTHESIS AND ANTIMICROBIAL SCREENING OF AMINO ACIDS CONJUGATED 2 AMINO4ARYLTHIAZOLE DERIVATIVES
... classes of ‘thiopeptide antibiotics’, a macrocyclic arrays of thiazole bearing amino acid/peptidic residues have been discovered from both microbial and marine origin. 6 They display a very promising antimicrobial activity and were recognized as one of the most ...
... classes of ‘thiopeptide antibiotics’, a macrocyclic arrays of thiazole bearing amino acid/peptidic residues have been discovered from both microbial and marine origin. 6 They display a very promising antimicrobial activity and were recognized as one of the most ...
Functional characterisation of the TUP5 gene in - diss.fu
... arginine content was reduced in tup5-1 compared to the wild type and root growth was restored in the mutant by exogenous supplementation of arginine. As an additional functional proof, a yeast mutant lacking ACOAT which was auxotrophic for arginine could restore its arginine autotrophy after transfo ...
... arginine content was reduced in tup5-1 compared to the wild type and root growth was restored in the mutant by exogenous supplementation of arginine. As an additional functional proof, a yeast mutant lacking ACOAT which was auxotrophic for arginine could restore its arginine autotrophy after transfo ...
Development of prokaryotic cell-free systems for synthetic
... efficiently produce protein without interference from cellular growth and metabolism. In addition, many systems are driven by T7 RNA polymerase expression (Krieg & Melton, 1987) to encourage as much protein production as possible. Completely “synthetic” cellfree systems from purified components (Shi ...
... efficiently produce protein without interference from cellular growth and metabolism. In addition, many systems are driven by T7 RNA polymerase expression (Krieg & Melton, 1987) to encourage as much protein production as possible. Completely “synthetic” cellfree systems from purified components (Shi ...
and Athletic Performance - Department of Mechanical Engineering
... like any cell in the body— must have a “blueprint” to specify the order in which amino acids should be put together to make the protein— in other words, to indicate which protein will be created. This blueprint is a gene in the cell’s nucleus, and the process by which the information gets out of th ...
... like any cell in the body— must have a “blueprint” to specify the order in which amino acids should be put together to make the protein— in other words, to indicate which protein will be created. This blueprint is a gene in the cell’s nucleus, and the process by which the information gets out of th ...
Leaf shape: genetic controls and environmental factors
... and is represented by leaves of most model plants, including Arabidopsis, Antirrhinum majus L. and Zea mays L. Simple leaves show more or less serration in the margin but are not separated into several units. On the other hand, tomato, rose and white clover are typical species with compound leaves, ...
... and is represented by leaves of most model plants, including Arabidopsis, Antirrhinum majus L. and Zea mays L. Simple leaves show more or less serration in the margin but are not separated into several units. On the other hand, tomato, rose and white clover are typical species with compound leaves, ...