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Molecular evolution of the melanocortin 1-receptor - Funpec-RP
Molecular evolution of the melanocortin 1-receptor - Funpec-RP

... melanic phenotypes in addition to the most common phenotype [e.g., the gray squirrel (Sciurus carolinensis)] (McRobie et al., 2009). The main candidate locus targeted was melanocortin 1-receptor (MC1R), a member of the G protein-coupled superfamily that acts as a pigment switch in the production of ...
IMPROVED PEPPER PLANT
IMPROVED PEPPER PLANT

... exogenous agents such as dead pollen extract, or of applying growth regulating substances, either natural or synthetic. In fact, in protected cultivation such as, for example, in the greenhouse, exogenous applications of growth regulators are frequently used in order to induce the formation of seedl ...
Powerpoint template for scientific posters (Swarthmore College)
Powerpoint template for scientific posters (Swarthmore College)

... The deficiency screens have candidate regions that consist genes that interact with runt. Two regions (556, 9715) most like they affect maintenance step. Preliminary experiments suggest their specificity. The systematic and comprehensive screen of 3L have confirmed 9 regions that are interacting wit ...
Focus Issue on Plastid Biology Update Novel
Focus Issue on Plastid Biology Update Novel

... cellular components against oxidative damage by ROS. These are unavoidable by-products of oxygenic photosynthesis and are generated by uncontrolled electron leakage mainly at PSI. ROS can generate deleterious effects and must be detoxified. Thereby, ROS function as important sinks for reducing power ...
Protein and Amino Acid Metabolism During and After Exercise
Protein and Amino Acid Metabolism During and After Exercise

... The effects of bouts of resistance exercise upon muscle amino acid intermediary metabolism have not been studied in detail, partly because the periods of work are too short to result in more than bursts of increased rates of ATP utilization and glycogenolysis, with little oxidative metabolism being ...
Polymorphic Variation in the Structure of Aerial
Polymorphic Variation in the Structure of Aerial

... mutation in the scl-1 gene could have occurred during the subsequent years of vegetative culture, it seems far more likely that the varient alleles existed at the time the monokaryons were first isolated. Thus three different alleles of the scl-1 gene were recovered from the same carpophore: scl-I+ ...
Nucleotide sequence of the Tn10 encoded tetracycline resistance
Nucleotide sequence of the Tn10 encoded tetracycline resistance

... Figure 5 Comparison of the Shine-Dalgarno sequences preceeding three possible reading frames. Homologies of three or more nucleotides are underlined [18]. In addition, the start and stop codons are shown, of a second hairpin structure in the transcript ahead of the terminator. The stem and loop size ...
Bacterial evolution and the cost of antibiotic resistance
Bacterial evolution and the cost of antibiotic resistance

... thereby causing detrimental side-effects. In the case of plasmidencoded resistance functions, bacteria must synthesize additional nucleic acids and proteins; this synthesis imposes an energetic burden [7] and the products that are synthesized may interfere with the cell’s physiology [12]. Resistant ...
Vincristine, Vincent Ting - UC Davis Department of Chemistry
Vincristine, Vincent Ting - UC Davis Department of Chemistry

... colon that move stool, which means that the patient will experience constipation. Toxic effects may include numbness, pain, tingling, headaches, rashes, a change in blood pressure, dizziness, nausea, vomiting, hearing problems, and hair loss. Effects are more common to those with poor liver function ...
[7] Semisynthesis of Proteins Containing Selenocysteine
[7] Semisynthesis of Proteins Containing Selenocysteine

... turns from yellow to colorless), glacial acetic acid is added dropwise until the pH is near 6.0. p-MethoxybenzyI chloride (1.44 ml; 10.64 mmol) is then added dropwise to the solution. The reaction proceeds quickly and is complete in 30 min. White crystals of selenium-benzylated selenocysteine are ap ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Preeclampsia is a potentially life-threatening disease that occurs exclusively in pregnant women during late gestation (>20 weeks). The two hallmark symptoms are hypertension and proteinuria, complicating at least 5% of pregnancies and are usually resolved upon delivery of the placenta (Lain and Rob ...
GIBBERELLIN BIOSYNTHESIS: Enzymes, Genes and Their
GIBBERELLIN BIOSYNTHESIS: Enzymes, Genes and Their

... The last review of GA biosynthesis in this series, by Graebe (38), was followed by several reviews covering this topic (68, 75, 121). Graebe’s article focused on GA-biosynthetic pathways in cell-free systems, characteristics of biosynthetic enzymes, and factors affecting GA production. He predicted ...
Genome-wide analysis by SNP Array
Genome-wide analysis by SNP Array

... Case 3: Detection of genomic changes in patient with premature ovarian failure presenting a normal Karyotype Patients with premature ovarian failure (POF) show partial deletions on chromosome X and Xautosome translocations. Seventy per cent of the deletions in the terminal end of chromosome X are re ...
Document
Document

... A patient in the advanced stages of the disease showing involuntary movements of the head and face. Photos courtesy of Professor Peter Harper, Cardiff. (b) Post mortem sections comparing normal brain (left) with brain from Huntington disease patient (right); note the loss of tissue in the Huntington ...
PHI-Canto video tutorial slides - PHI-base
PHI-Canto video tutorial slides - PHI-base

Role of NAD+-Dependent Malate Dehydrogenase in the Metabolism
Role of NAD+-Dependent Malate Dehydrogenase in the Metabolism

... 5 mM), glycerate, lactate, α-ketoglutarate, citrate, serine, pyrophosphate (1 mM) or КH2PO4 (10 mM) were tested as potential effectors. To test the effect of divalent metals on the MDH activity, aquatic stock solutions of CuCl2, MgCl2, MnCl2, CoCl2, BaCl2, ZnCl2 or CaCl2 were added to a final concen ...
The Frequency Distribution of Nucleotide Variation in Drosophila
The Frequency Distribution of Nucleotide Variation in Drosophila

... 0.11). This dependence of the statistical results on period data could be indicative of locus effects or could be attributable to reduced power associated with removal of a large amount of data from the analysis. The conclusion of roughly equal numbers of preferred and unpreferred fixations is based ...
WS Procs 975 x 65
WS Procs 975 x 65

... representation to the Dependency Pattern Sets (DPS) representation. DPS representation is a generalized model of string representation, which can model adjacent nucleotide dependency. Although it has a lower descriptive power than SPSP representation, experimental results on real biological data sho ...
ARTICLES
ARTICLES

... The 32-38 pair controls misreading of GUC near-cognate codon As sequence variation in the 32-38 pair did not affect decoding efficiency, we turned our investigation toward its decoding fidelity. The wobble pairing at the second G35 in tRNAAla GGC to a near-cognate valine codon, GUC, would be expecte ...
Unit II presentation
Unit II presentation

... • Sometimes develop splenomegally but do not benefit from splenectomy. ...
Anterior-posterior patterning within the
Anterior-posterior patterning within the

... expressed relative to the ges-1 ATG codon. The ges-1∆B::GFP/lacZ transgene was constructed by inserting the 3.3 kb ges-1∆B upstream region (−3317 to −3) into the multiple cloning site (HindIII-SalI) of the vector pPD96.04 (kindly provided by A. Fire, Carnegie Institute of Washington). Transformation ...
- Wiley Online Library
- Wiley Online Library

... France). Cd tolerance was measured under controlled glasshouse conditions (13 h light d 1, 100 lmol photons m 2 s 1 irradiance, and 20°C : 17°C, day : night) at the Free University of Brussels. Vessels were randomly distributed in the chamber and moved around once a week during the change of nutrien ...
mic.sgmjournals.org
mic.sgmjournals.org

... analysed by injecting 5 ml of this extract into a Agilent 1100 series modular HPLC system (Agilent Technologies) equipped with a diode array detector and a mass spectrometer (Agilent XCT Plus Ion Trap). Whole-cell extracts were separated on a Luna C18(2) column (26150 mm, 5 mm, Phenomenex) using the ...
Genetic and epigenetic risks of intracytoplasmic sperm injection
Genetic and epigenetic risks of intracytoplasmic sperm injection

... CBAVD have been described and they are almost all related to defective CFTR protein processing [17]. In addition, the missence R117H mutation in exon 4 is also related to CBAVD in association with the 5T variant [20]). Thus, testing for R117H and 5T/7T/9T polymorphism is important in the infertility ...
LAZY1 controls rice shoot gravitropism through
LAZY1 controls rice shoot gravitropism through

... were first identified to participate in auxin transport because the phenotypes of pin1 and pin2 were similar to those of wild-type plants grown in the presence of auxin transport inhibitors [23, 24], and these two proteins are localized on plasma membranes in an asymmetric manner [25, 26]. PIN3, ano ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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