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The Nervous System
The Nervous System

... • Canadian born Michael J. Fox was Diagnosed with Parkinson's disease at the age of 30. • In 1998 he began his public crusade for this disease. • In 2008, he receive an honourary degree from the University of British Columbia: an honour that he said made him feel deeply humbled and honoured. • Fox w ...
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Spinal cord and reflexes

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Genetic dissection of neural circuits underlying sexually dimorphic
Genetic dissection of neural circuits underlying sexually dimorphic

... valuable resource for research as recent advances in the application of CRISPR-Cas systems for gene editing have greatly increased the speed and efficiency of generating genetic knockouts [68–70]. The use of targeted gene knockouts has made it possible to study the contributions of contact-based VNO ...
Spinal cord and reflexes
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...  Stimulating inhibitory neurons  Creating IPSPs at reflex motor neurons  Suppressing postsynaptic neurons ...
Amygdala oscillations and the consolidation of
Amygdala oscillations and the consolidation of

... synaptic plasticity and memory. For instance, slow-wave sleep (SWS) enhances cortical reorganization of ocular dominance columns in developing visual cortex following monocular deprivation [a]. Moreover, it has been shown that sleep is essential after visual training for the consolidation of some fo ...
The impact of continuity editing in narrative film on event segmentation
The impact of continuity editing in narrative film on event segmentation

... An alternative reason that cuts are not perceptually salient stems from the nature of continuity editing. The purpose of continuity editing is to tell a story by creating a spatially and temporally coherent sequence of events and actions (Bordwell, 1985; Bordwell & Thompson, 2006) with the end resul ...
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Anterior Cingulate Conflict Monitoring and Adjustments in Control
Anterior Cingulate Conflict Monitoring and Adjustments in Control

... the subsequent trial, as predicted by the conflict hypothesis. Finally, we examined a closely related set of predictions of the conflict hypothesis, that ACC error-related activity should also be followed by an increase in PFC activity and corresponding adjustments in performance (18, 19). According ...
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fluctuations in somatosensory responsiveness and baseline firing
fluctuations in somatosensory responsiveness and baseline firing

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Crocodilian Forebrain: Evolution and Development
Crocodilian Forebrain: Evolution and Development

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Chapter 18: Control and Coordination
Chapter 18: Control and Coordination

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new insights into the functions of the superior temporal cortex
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... Superior temporal cortex and neglect. Experimental lesions of the monkey posterior parietal cortex failed to elicit the complex behavioural abnormalities typically seen with spatial neglect in humans (for reviews, see REFS 15,16). This led to controversy about the anatomical and functional homology ...
Experimental Brain Research 221(1)
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... TUNEL staining APOPTOSIS in situ Detection Kit (WAKO, Osaka, Japan) was used for TUNEL staining, according to the manufacturer’s instruction. After deparaVinization and hydration, sections were incubated with protein digestion enzyme solution for 5 min at 37°C, The sections were treated with TdT sol ...
$doc.title

... The   course   will   provide   you   with   a   detailed   knowledge   of   some   specific   areas   of   neuroscience,   and   equip   you   with   the   tools   to   extrapolate   this   knowledge   into   areas   that   are  not  cover ...
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Experimental Models of Parkinson`s Disease: Insights from Many

... the brain, however, if administered systemically in the neonatal animal, because the blood-brain barrier is not fully developed. Because all catecholaminergic neurons are affected by 6-OHDA, several strategies can be used to specifically target the dopaminergic system. The uptake of 6-OHDA into nore ...
pdf - Olin Neuropsychiatry Research Center
pdf - Olin Neuropsychiatry Research Center

... increased relative to the Go stimulus. Similarly, interpretation of the findings of Braver et al (2001), who also employed a task in which Go and NoGo trials were equally probable, is complicated by the inclusion of multiple Go stimulus variants (i.e., any letter that was not an ‘X’) versus only a s ...
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... We have previously shown that picrotoxin (PCT) applied to the locust antennal lobe selectively blocks the fast inhibitory synapse between local and projection neurons and abolishes their oscillatory synchronization: this manipulation altered neither the response profiles of projection neurons to odo ...
The subtle body: an interoceptive map of central nervous system
The subtle body: an interoceptive map of central nervous system

... practices,6–8 and the subtle body may prove more useful than current maps, because it categorizes contemplative practices not on the basis of phenomenological or procedural factors but on underlying neural mechanisms.4 (2) Given the brain’s complexity, current efforts to make sense of the explosion ...
Dopamine`s Actions in Primate Prefrontal Cortex
Dopamine`s Actions in Primate Prefrontal Cortex

... VIII. Future Challenges . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Physiology of Gonadotropin-Releasing Hormone (GnRH): Beyond
Physiology of Gonadotropin-Releasing Hormone (GnRH): Beyond

... could be mediated by a possible intervention on local synthesis of estrogen, known to affect synaptogenesis and expression of both spinophilin and synaptophisin [29]. This observation also suggests that estrus cycle - dependent synaptogenesis, occurring in the rat female hippocampus, may be regulate ...
Increased prefrontal activity and reduced motor cortex
Increased prefrontal activity and reduced motor cortex

... within the scanner because of difficulties having equipment in the magnetic field. Simple movements, such as wrist flexions, are easily made. However, maximum contractions are more difficult as well as more likely to result in movements of the head, which then can lead to poor quality of the data. N ...
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Cognitive neuroscience



Cognitive neuroscience is an academic field concerned with the scientific study of biological substrates underlying cognition, with a specific focus on the neural substrates of mental processes. It addresses the questions of how psychological/cognitive functions are produced by neural circuits in the brain. Cognitive neuroscience is a branch of both psychology and neuroscience, overlapping with disciplines such as physiological psychology, cognitive psychology, and neuropsychology. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neuropsychology, and computational modeling.Due to its multidisciplinary nature, cognitive neuroscientists may have various backgrounds. Other than the associated disciplines just mentioned, cognitive neuroscientists may have backgrounds in neurobiology, bioengineering, psychiatry, neurology, physics, computer science, linguistics, philosophy, and mathematics.Methods employed in cognitive neuroscience include experimental paradigms from psychophysics and cognitive psychology, functional neuroimaging, electrophysiology, cognitive genomics, and behavioral genetics. Studies of patients with cognitive deficits due to brain lesions constitute an important aspect of cognitive neuroscience. Theoretical approaches include computational neuroscience and cognitive psychology.Cognitive neuroscience can look at the effects of damage to the brain and subsequent changes in the thought processes due to changes in neural circuitry resulting from the ensued damage. Also, cognitive abilities based on brain development is studied and examined under the subfield of developmental cognitive neuroscience.
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