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Genespring FAQ - UNC Center for Bioinformatics
Genespring FAQ - UNC Center for Bioinformatics

... tabs will allow you to set which data each axis represents. Once these are set to the two samples or conditions you are interested in comparing, click on the “Lines to Graph” tab. Here you can set the fold change lines to any value you wish. Click OK. Right-Click on the region you are interested in: ...
Insights into three whole-genome duplications gleaned
Insights into three whole-genome duplications gleaned

... substitution rates on the branches leading to the two paralogs. Expression data from RNA sequencing were used to determine whether the faster evolving ...
Prospective diagnostic analysis of copy number variants using SNP
Prospective diagnostic analysis of copy number variants using SNP

... which have important roles in neurodevelopment and/or neurotransmission.3,14–17 However, most CNVs and variants in genes involved in autism so far are also found in other neurodevelopmental disorders such as ID without autistic features and/or schizophrenia.12,18 Recent studies point to polygenic or ...
Popped Secret: The Mysterious Origin of Corn HHMI BioInteractive
Popped Secret: The Mysterious Origin of Corn HHMI BioInteractive

... 2. Dr. Beadle crossed teosinte and maize to produce F1 offspring. He then crossed those plants to produce an F2 generation. Dr. Beadle planted 50,000 F2 seeds. When the offspring of these F2 seeds grew, about 100 looked like teosinte and about 100 looked like maize. Based on this result, how many ge ...
Sequence Heterogeneities Among 16s
Sequence Heterogeneities Among 16s

... different but closely related genera (enterobacteria) and for different species or strains within a single genus (Escherichia or Salmonella), and finally how similar are the ribosomal operons within a single organism (Escherichia coli). These sequences have been analyzed by neighbor-joining, maximum ...
Linkage Analysis
Linkage Analysis

...  Good families for linkage studies: Large and informative  Small families: more difficult (eg. Cystic Fibrosis) ...
Mendelian genetics
Mendelian genetics

... of separable factors (now called alleles of a gene), one inherited from each parent, and when an individual produces an egg or sperm cell, only one or the other of this gene pair is randomly transmitted (alleles segregate randomly) (Figs. 14.5, 14.9, and 14.14 (7th) (Figs. 14.4, 14.8, and 14.14 (6th ...
Indinavir inhibits sterol-regulatory element-binding protein
Indinavir inhibits sterol-regulatory element-binding protein

... increases the risk of cardiovascular complications [5,6]. Recent studies revealed that HAART-related adverse effects are common and persist in patients remaining on ...
Linear Dominance Relationship among Four Class
Linear Dominance Relationship among Four Class

... enzyme, resulting in a wrinkled-seed character (Bhattacharyya et al. 1990). To date, dominant/recessive alleles have been isolated and characterized for many genes related to several phenomena in various plant species (Glazebrook 1999, Szymanski et al. 2000, Theisen 2001). The biological phenomena r ...
special - Microbiology
special - Microbiology

... To address this question, high-copy-number plasmids that contained either afsR or afsS were made and both were shown to be capable of stimulating Act production in both S. coelicolor and S.lividans; however, the degree of stimulation mediated by afxR was significantly greater than that produced by a ...
H 2
H 2

... – Are O type good recipients? – Because people with type O blood produce both A and B antibodies, they can receive blood only from other type O donors • Their antibodies would attack any donated blood cells bearing A or B glycoproteins ...
PopCycle Tutorial
PopCycle Tutorial

... in the upper left corner of the window, with eggs and sperm floating and swimming around in it. The darker gametes carry allele A; the lighter ones carry allele a. The allele frequencies in the default gene pool are 0.5 for A and 0.5 for a. We want to simulate a population in which the frequencies a ...
Adaptive Evolution of 5#HoxD Genes in the
Adaptive Evolution of 5#HoxD Genes in the

... Shubin and Marshall 2000). In mammals, the ancestral amniote manus is typically characterized by five separate digits (pentadactyly), with each digit consisting of carpals, metacarpals, and phalanges running from proximal to distal axes. In general, each digit ray consists of one metacarpal and eith ...
Detection of mutation status of IgVH genes and minimal residual
Detection of mutation status of IgVH genes and minimal residual

... tools to evaluate genome wide parameters and defects. On the genomic level matrix CGH (comparative genomic hybridization against the matrix of defined DNA fragments) is a sensitive test allowing the detection of novel recurrent aberrations of potential pathogenic and prognostic importance[39]. On th ...
Primer on Molecular Genetics
Primer on Molecular Genetics

... Each DNA molecule contains many genes—the basic physical and functional units of heredity. A gene is a specific sequence of nucleotide bases, whose sequences carry the information required for constructing proteins, which provide the structural components of cells and tissues as well as enzymes for ...
Developmental Psychobiology - Champagne Lab
Developmental Psychobiology - Champagne Lab

... offspring development. This article shall review four major sources of such parentof-origin effects. Firstly, there is increasing evidence that genes inherited on the sex chromosomes including the nonpseudoautosomal part of the Y chromosome that is only inherited from fathers to sons, contribute to ...
Gradzial-Variety Development - California Cling Peach Board
Gradzial-Variety Development - California Cling Peach Board

... transferred as well. Over the last 6 years we have been involved in a rigorous, recurrent (generation-by-generation) selection for desirable genes and against undesirable traits as a way to purge out unwanted traits. This process, known as gene introgression, is relatively inefficient in tree crops ...
Applied and Environmental Microbiology
Applied and Environmental Microbiology

... Nitrogenase activity was measured by acetylene reduction 21 days after inoculation. Student’s t test was performed to analyze the differences between nodule numbers in the different treatments. Bacteroid isolation. Nodules from 6 to 10 plants harvested 23 and 28 days after inoculation were crushed i ...
GIN Transposons: Genetic Elements Linking Retrotransposons and
GIN Transposons: Genetic Elements Linking Retrotransposons and

... a large set of unknown sequences from a variety of vertebrates (just one sequence per species) formed a monophyletic group (fig. 1). Detailed analyses of the structure and chromosomal positions of these sequences indeed indicated that they correspond to a novel gene, a GIN1 paralog. First, no struct ...
Introduction: - Statistical Science
Introduction: - Statistical Science

... optimistic results when assessing significance. This may lead to too many sets passing an FDR cutoff of 0.25. For example, the table shows the differences between phenotype label and gene tag permutations for the Gender dataset example. The large number of gene sets passing the test using gene tag p ...
Analysis of expressed sequence tags from the Huperzia serrata leaf
Analysis of expressed sequence tags from the Huperzia serrata leaf

... nucleotide sequences from H . serrata available in the NCBI database. The limited information on the genetic contents of this plant triggered our efforts to construct a cDNA library from the H . serrata leaf. The objective of this study was to identify the functional genes in H . serrata, especially ...
Genetic Testing for Colorectal Cancer Susceptibility GENE.00028
Genetic Testing for Colorectal Cancer Susceptibility GENE.00028

... Anthem UM Services, Inc., a separate company, is the licensed utilization review agent that performs utilization management services on behalf of your health benefit plan or the administrator of your health benefit plan. ...
Polycomb Group silencers collaborate with Notch pathway to cause
Polycomb Group silencers collaborate with Notch pathway to cause

... HpaII will not cut at its recognition sequence if it contains a methylated cytosine (mCCGG), both MspI and HpaII digestion will be blocked if both cytosines are methylated (mCmCGG). ...
Fig. 4 - Cambridge University Press
Fig. 4 - Cambridge University Press

... known hamster sequences when other species were used to obtain primers for unpublished hamster gene sequences. Statistical analysis From each group of ten hamsters, we obtained a complete set of results for seven to eight hamsters. Although partial least square (PLS) statistical methods (see explana ...
Open access article
Open access article

... We have established tools for forward and reverse genetic analysis of the legume Lotus (Lotus japonicus). A structured population of M2 progeny of 4,904 ethyl methanesulfonate-mutagenized M1 embryos is available for single nucleotide polymorphism mutation detection, using a TILLING (for Targeting In ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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