 
									
								
									Genes for Two Mitochondrial Ribosomal Proteins in
									
... Mitochondrial genomes are derived from the genome of a bacterial endosymbiont, with many genes having been lost or transferred to the nucleus early in mitochondrial evolution (reviewed by Gray, 1992; Gray et al., 1999). The transfer of mitochondrial genes to the nucleus and functional activation has ...
                        	... Mitochondrial genomes are derived from the genome of a bacterial endosymbiont, with many genes having been lost or transferred to the nucleus early in mitochondrial evolution (reviewed by Gray, 1992; Gray et al., 1999). The transfer of mitochondrial genes to the nucleus and functional activation has ...
									Genome reduction as the dominant mode of evolution
									
... become clear already in the pre-genomic era [18]. Comparative genomics reinforced the complex relationships between the different levels of complexity in the most convincing manner by demonstrating the lack of a simple link between genomic and organismal complexities [19]. Suffice it to note that th ...
                        	... become clear already in the pre-genomic era [18]. Comparative genomics reinforced the complex relationships between the different levels of complexity in the most convincing manner by demonstrating the lack of a simple link between genomic and organismal complexities [19]. Suffice it to note that th ...
									Retina-Specific Expression of 5A11/Basigin-2, a
									
... cycling parameters listed earlier, found a clone containing a 500-bp insert that aligned within the exon 1 region, as well as the intron 1 region of the mouse Basigin gene after a BLAST search.20 A primer B6799 (5⬘-CTGGTTTCCTCAAGGCACCATGTC), which aligns within intron 1 starting at base 6799 of the ...
                        	... cycling parameters listed earlier, found a clone containing a 500-bp insert that aligned within the exon 1 region, as well as the intron 1 region of the mouse Basigin gene after a BLAST search.20 A primer B6799 (5⬘-CTGGTTTCCTCAAGGCACCATGTC), which aligns within intron 1 starting at base 6799 of the ...
									Replication studies in longevity: puzzling findings in Danish
									
... in Danes a significant gene–sex interaction relevant to Long alleles (more than 37 repeats). The different findings in Denmark and Italy suggest that gene\longevity associations are populationspecific, and heavily affected by the population-specific genetic and environmental history. ...
                        	... in Danes a significant gene–sex interaction relevant to Long alleles (more than 37 repeats). The different findings in Denmark and Italy suggest that gene\longevity associations are populationspecific, and heavily affected by the population-specific genetic and environmental history. ...
									The bHLH Class Protein pMesogenin1 Can Specify Paraxial
									
... A new bHLH gene from mouse that we call pMesogenin1 (referring to paraxial mesoderm-specific expression and regulatory capacities) and its candidate ortholog from Xenopus were isolated and studied comparatively. In both organisms the gene is specifically expressed in unsegmented paraxial mesoderm an ...
                        	... A new bHLH gene from mouse that we call pMesogenin1 (referring to paraxial mesoderm-specific expression and regulatory capacities) and its candidate ortholog from Xenopus were isolated and studied comparatively. In both organisms the gene is specifically expressed in unsegmented paraxial mesoderm an ...
									Biology Chapter 11: Homework Hmwrk 11
									
... 3. What is a trait? List all of the traits that Mendel looked at. 4. Define genes and alleles. 5. Draw out your family tree starting with your grandparents. Label the P generation, the F1 generation and the F2 generation. Hmwrk 11-2 1. Define probability. What is the probability if I flip a coin tha ...
                        	... 3. What is a trait? List all of the traits that Mendel looked at. 4. Define genes and alleles. 5. Draw out your family tree starting with your grandparents. Label the P generation, the F1 generation and the F2 generation. Hmwrk 11-2 1. Define probability. What is the probability if I flip a coin tha ...
									the Gene Ontology
									
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers.  necessary for high-throughput “omics” datasets  allows data sharing across databases ...
                        	... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers.  necessary for high-throughput “omics” datasets  allows data sharing across databases ...
									How is the biological information arranged in genome?
									
... Pho2p facilitates interaction with Pho4p in S. cerevisiae. Other interaction of proteins could be identified from the same way (Sequence Spectrum Method, described later, refs. [4,5]). The study for the entire genomic base sequences were not so much, because we carried a few effective tools, includi ...
                        	... Pho2p facilitates interaction with Pho4p in S. cerevisiae. Other interaction of proteins could be identified from the same way (Sequence Spectrum Method, described later, refs. [4,5]). The study for the entire genomic base sequences were not so much, because we carried a few effective tools, includi ...
									Selection at the Wobble Position of Codons Read by the Same tRNA
									
... an extensive set of data (V. E. Velculescu, personal communication) derived from yeast transcriptome analysis (Velculescu et al. 1997). These data, which were obtained under three different growth conditions (logarithmic, G2/M transition, and stationary), refer to a total of 60,633 yeast mRNAs, each ...
                        	... an extensive set of data (V. E. Velculescu, personal communication) derived from yeast transcriptome analysis (Velculescu et al. 1997). These data, which were obtained under three different growth conditions (logarithmic, G2/M transition, and stationary), refer to a total of 60,633 yeast mRNAs, each ...
									IGR-ANNOT: A Multiagent System for InterGenic - Inf
									
... • There are many tools and techniques to compare complete genomes and coding regions, but there is a lack for techniques for compare non-coding regions of DNA, which contains regulatory elements. • Many of the differences between species may be attributed to changes in the regulation of transcriptio ...
                        	... • There are many tools and techniques to compare complete genomes and coding regions, but there is a lack for techniques for compare non-coding regions of DNA, which contains regulatory elements. • Many of the differences between species may be attributed to changes in the regulation of transcriptio ...
									GmPep914, an Eight-Amino Acid Peptide Isolated
									
... increase in the extracellular pH of the media (Felix and Boller, 1995). An alkalinization assay was developed in the Ryan laboratory that has been a key to the purification of the defense peptides HypSys and AtPeps, as well as the peptide Rapid Alkalinization Factor (Pearce et al., 2001b), which is ...
                        	... increase in the extracellular pH of the media (Felix and Boller, 1995). An alkalinization assay was developed in the Ryan laboratory that has been a key to the purification of the defense peptides HypSys and AtPeps, as well as the peptide Rapid Alkalinization Factor (Pearce et al., 2001b), which is ...
									Regulation and Flexibility of Genomic Imprinting
									
... tolerated, and crosses between different ploidies can produce viable seeds. Consistent with the predictions made from the parental conflict theory, a cross between a tetraploid mother and diploid father (4n 3 2n) produces small seeds, whereas the reciprocal cross (2n 3 4n) produces larger seeds (Sco ...
                        	... tolerated, and crosses between different ploidies can produce viable seeds. Consistent with the predictions made from the parental conflict theory, a cross between a tetraploid mother and diploid father (4n 3 2n) produces small seeds, whereas the reciprocal cross (2n 3 4n) produces larger seeds (Sco ...
									Structure, expression and chromosomal location of the Oct
									
... uncloned "gap" between Q and T. In situ analysis of early preimplantation embryos reveals that Oct-4 is expressed both maternally and zygotically. Surprisingly, zygotic expression is not detectable until the 8-cell stage when compaction begins. In addition to Oct-4, several Oct-4-related genes are p ...
                        	... uncloned "gap" between Q and T. In situ analysis of early preimplantation embryos reveals that Oct-4 is expressed both maternally and zygotically. Surprisingly, zygotic expression is not detectable until the 8-cell stage when compaction begins. In addition to Oct-4, several Oct-4-related genes are p ...
									Genes and physical fitness
									
... a type of association of two polymorphisms located close to each other on the same chromosome and inherited as a haplotype. If there is then an association of a polymorphism with a trait, it does not functionally affect the development of this trait, but most probably remains in the linkage disequil ...
                        	... a type of association of two polymorphisms located close to each other on the same chromosome and inherited as a haplotype. If there is then an association of a polymorphism with a trait, it does not functionally affect the development of this trait, but most probably remains in the linkage disequil ...
									EXERCISE 4: Principles of Heredity: Human Genetics Learning
									
... Godfrey H. Hardy and Wilhelm Weinberg, independently devised several mathematical equations that could be used in two different ways of interest to biologists. These equations are used to predict the allele and genotype percentages in a population. Then these equations can be used to show changes in ...
                        	... Godfrey H. Hardy and Wilhelm Weinberg, independently devised several mathematical equations that could be used in two different ways of interest to biologists. These equations are used to predict the allele and genotype percentages in a population. Then these equations can be used to show changes in ...
									A Conserved Molecular Framework for Compound Leaf Development
									
... search tree) from this multiple sequence alignment were generated with PhyML(2) using optimal amino acide substitution model JTT + G select using ModelGenerator (v0.84)(3). The NAC1 protein from A. thaliana was used as outgroup. Bootstrap confidence values were obtained by 100 replicates and only bo ...
                        	... search tree) from this multiple sequence alignment were generated with PhyML(2) using optimal amino acide substitution model JTT + G select using ModelGenerator (v0.84)(3). The NAC1 protein from A. thaliana was used as outgroup. Bootstrap confidence values were obtained by 100 replicates and only bo ...
									Computational disease gene identification
									
... pancreatic b-cells and insulin secretion [e.g. MODY diabetes (14)] or adipose tissue development [e.g. lipodystrophy syndromes (15)]. These single genetic changes can result in highly penetrant monogenic diabetes, suggesting that more subtle genetic changes in these pathways might play a role in det ...
                        	... pancreatic b-cells and insulin secretion [e.g. MODY diabetes (14)] or adipose tissue development [e.g. lipodystrophy syndromes (15)]. These single genetic changes can result in highly penetrant monogenic diabetes, suggesting that more subtle genetic changes in these pathways might play a role in det ...
									tRNA and Translation
									
... 3. The proper arrangement of almost 600 amino acids results in normal formation of the hemoglobin molecule. According to the question above, one mistake involving the replacement of the amino acid ______________________________________ by the amino acid ____________________________________ can resul ...
                        	... 3. The proper arrangement of almost 600 amino acids results in normal formation of the hemoglobin molecule. According to the question above, one mistake involving the replacement of the amino acid ______________________________________ by the amino acid ____________________________________ can resul ...
									DNA Replication
									
... This is because it can assemble nucleotides only as it travels in the 3' → 5‘ direction. As the helix is uncoiled, DNA polymerase assembles short segments of nucleotides along the template strand in the direction away from the replication fork. After each complement segment is assembled, the DNA pol ...
                        	... This is because it can assemble nucleotides only as it travels in the 3' → 5‘ direction. As the helix is uncoiled, DNA polymerase assembles short segments of nucleotides along the template strand in the direction away from the replication fork. After each complement segment is assembled, the DNA pol ...
									Dragon Genetics -- Independent Assortment and Genetic Linkage
									
... To test whether baby dragons with wings and baby dragons without wings will be equally likely to have big horns, you will carry out a simulation of the simultaneous inheritance of the genes for wings and horns. Since the father is homozygous (wwhh), you know that all of the father's sperm will be wh ...
                        	... To test whether baby dragons with wings and baby dragons without wings will be equally likely to have big horns, you will carry out a simulation of the simultaneous inheritance of the genes for wings and horns. Since the father is homozygous (wwhh), you know that all of the father's sperm will be wh ...
									Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant
									
... mutants is rescued by inactivation of mCry2. A similar rescue was observed for mCry1 expression: both amplitude and timing of mCry1 oscillation in Per2Brdm1/ mCry2−/− mutant animals was not significantly different from that observed in wild-type animals (Fig. 2c). Per2Brdm1 mutant mice displayed abn ...
                        	... mutants is rescued by inactivation of mCry2. A similar rescue was observed for mCry1 expression: both amplitude and timing of mCry1 oscillation in Per2Brdm1/ mCry2−/− mutant animals was not significantly different from that observed in wild-type animals (Fig. 2c). Per2Brdm1 mutant mice displayed abn ...
									Bio1B - Integrative Biology
									
... of separable factors (now called alleles of a gene), one inherited from each parent, and when an individual produces an egg or sperm cell, only one or the other of this gene pair is randomly transmitted (alleles segregate randomly) (Figs. 14.5 and 14.9 in 7th and 8th). The important feature of Mende ...
                        	... of separable factors (now called alleles of a gene), one inherited from each parent, and when an individual produces an egg or sperm cell, only one or the other of this gene pair is randomly transmitted (alleles segregate randomly) (Figs. 14.5 and 14.9 in 7th and 8th). The important feature of Mende ...
									Mendelian inheritance
									
... have accused Von Tschermak of not truly understanding the results at all.[1] Regardless, the "re-discovery" made Mendelism an important but controversial theory. Its most vigorous promoter in Europe was William Bateson, who coined the term "genetics" and "allele" to describe many of its tenets. The ...
                        	... have accused Von Tschermak of not truly understanding the results at all.[1] Regardless, the "re-discovery" made Mendelism an important but controversial theory. Its most vigorous promoter in Europe was William Bateson, who coined the term "genetics" and "allele" to describe many of its tenets. The ...
									Chapter 15 The Chromosomal Basis of Inheritance
									
... If a sex-linked trait is due to a recessive allele, a female will express this phenotype only if she is homozygous. ° Heterozygous females are carriers for the recessive trait. ° Because males have only one X chromosome (hemizygous), any male receiving the recessive allele from his mother will expre ...
                        	... If a sex-linked trait is due to a recessive allele, a female will express this phenotype only if she is homozygous. ° Heterozygous females are carriers for the recessive trait. ° Because males have only one X chromosome (hemizygous), any male receiving the recessive allele from his mother will expre ...
									DNA mutation bracelets
									
... 1) What changes in the RNA sequence were caused by the changes in the DNA? When the DNA sequence was changed, the RNA reading frame was shifted. 2) What changes in amino acids were caused by the changes in the DNA? Different amino acid were coded after the deletion shifted the sequence. 3) What happ ...
                        	... 1) What changes in the RNA sequence were caused by the changes in the DNA? When the DNA sequence was changed, the RNA reading frame was shifted. 2) What changes in amino acids were caused by the changes in the DNA? Different amino acid were coded after the deletion shifted the sequence. 3) What happ ...
RNA-Seq
 
                        RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									