X-ray Crystallographic Structure of Ibuprofen Bound to Human
... The fatty acid-binding proteins (FABPs) are a family of nine structurally related proteins, which bind to long-chain fatty acids with high affinity. Fatty acid binding proteins were first discovered in 1972, while conducting studies on the factors that regulate the uptake of intestinal fatty acids i ...
... The fatty acid-binding proteins (FABPs) are a family of nine structurally related proteins, which bind to long-chain fatty acids with high affinity. Fatty acid binding proteins were first discovered in 1972, while conducting studies on the factors that regulate the uptake of intestinal fatty acids i ...
Planctomycetes and eukaryotes: A case of analogy not homology
... evidence indicates that despite a superficial cytological similarity between the membrane configurations in the PVC bacteria and eukaryotes, the structures are not homologous. A similar situation exists with respect to the mechanism of protein uptake recently described in PVC and declared to be homo ...
... evidence indicates that despite a superficial cytological similarity between the membrane configurations in the PVC bacteria and eukaryotes, the structures are not homologous. A similar situation exists with respect to the mechanism of protein uptake recently described in PVC and declared to be homo ...
Sample Chapter
... membrane proteins can be classified according to their shapes. One group of proteins, for example, consists of tightly coiled, rodlike molecules embedded in the phospholipid bilayer. Some such fibrous proteins completely span the membrane; that is, they extend outward from its surface on one end, wh ...
... membrane proteins can be classified according to their shapes. One group of proteins, for example, consists of tightly coiled, rodlike molecules embedded in the phospholipid bilayer. Some such fibrous proteins completely span the membrane; that is, they extend outward from its surface on one end, wh ...
Cell cycle parameters of hESC are highly similar to - HAL
... generation of extraembryonic tissues. These structures not only ensure nutrients supply to the embryo but also play important role in the establishment of the basic body plan of the embryo. Recently, a global gene expression profiling technology has been adapted and applied to pre-implantation embry ...
... generation of extraembryonic tissues. These structures not only ensure nutrients supply to the embryo but also play important role in the establishment of the basic body plan of the embryo. Recently, a global gene expression profiling technology has been adapted and applied to pre-implantation embry ...
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... in contact with the endodermal precursor (E.x), and a somatic daughter, D, which was in contact with the C daughter cell (C.x) (3/3 cases) (Fig. 1D), as observed in intact embryos (20/20 cases). However, we were surprised to find that the P4 cell in the P2 isolates was frequently generated in an inv ...
... in contact with the endodermal precursor (E.x), and a somatic daughter, D, which was in contact with the C daughter cell (C.x) (3/3 cases) (Fig. 1D), as observed in intact embryos (20/20 cases). However, we were surprised to find that the P4 cell in the P2 isolates was frequently generated in an inv ...
Genetically Engineered Cell Lines: Characterisation and
... moloney leukemia virus. The most suitable promoter will depend on the nature of the host cell. In summary, there is no general rule for choosing a vector applicable to all cell lines and suitable for all applications. At present, retroviral vectors are the most versatile gene carriers in that they c ...
... moloney leukemia virus. The most suitable promoter will depend on the nature of the host cell. In summary, there is no general rule for choosing a vector applicable to all cell lines and suitable for all applications. At present, retroviral vectors are the most versatile gene carriers in that they c ...
Cell cycle regulation during early mouse embryogenesis.
... generation of extraembryonic tissues. These structures not only ensure nutrients supply to the embryo but also play important role in the establishment of the basic body plan of the embryo. Recently, a global gene expression profiling technology has been adapted and applied to pre-implantation embry ...
... generation of extraembryonic tissues. These structures not only ensure nutrients supply to the embryo but also play important role in the establishment of the basic body plan of the embryo. Recently, a global gene expression profiling technology has been adapted and applied to pre-implantation embry ...
Innovative Purification Protocol for Heparin Binding
... between several related structures while they perform their biological function, these functional rearrangements, these tertiary and quaternary structures are referred to as conformations and transition between them are called conformational changes [7, 14, 28]. The structure of proteins can be divi ...
... between several related structures while they perform their biological function, these functional rearrangements, these tertiary and quaternary structures are referred to as conformations and transition between them are called conformational changes [7, 14, 28]. The structure of proteins can be divi ...
Document
... • proteins within the cell that assist with appropriate folding of proteins • their role is to prevent misfolding rather than actively direct correct folding • can act to delay any folding (e.g. as the nascent polypeptide chain emerges from the ribosome) • can also ‘rescue’ misfolded proteins to the ...
... • proteins within the cell that assist with appropriate folding of proteins • their role is to prevent misfolding rather than actively direct correct folding • can act to delay any folding (e.g. as the nascent polypeptide chain emerges from the ribosome) • can also ‘rescue’ misfolded proteins to the ...
Electron Microscopic Observations on the Excretion of Cell
... through it may be incorporated by, for example, pinocytosis (Lewis, 1931; Palade, 1953) or may be excreted from the cells. Although there may exist several mechanisms for the excretion or secretion of cellular products (Kurosumi, 1961, 1962), the mechanism of reversed pinocytosis (Palade, 1959, 1960 ...
... through it may be incorporated by, for example, pinocytosis (Lewis, 1931; Palade, 1953) or may be excreted from the cells. Although there may exist several mechanisms for the excretion or secretion of cellular products (Kurosumi, 1961, 1962), the mechanism of reversed pinocytosis (Palade, 1959, 1960 ...
How will Hemoglobin Affect the Winner of this Year`s Super Bowl
... acid has a certain chemical character in relation to water molecules. Some amino acids love being around water (Hydrophilic), some hate water and hide from it (Hydrophobic), and for some, it doesn’t matter as much. Proteins do not exist as a string of amino acids, but must fold into a 3 dimensional ...
... acid has a certain chemical character in relation to water molecules. Some amino acids love being around water (Hydrophilic), some hate water and hide from it (Hydrophobic), and for some, it doesn’t matter as much. Proteins do not exist as a string of amino acids, but must fold into a 3 dimensional ...
Prokaryotic Cells
... • The substance inside the plasma membrane • Thick, semi transparent • Made of 80% water, enzymes, carbohydrates ...
... • The substance inside the plasma membrane • Thick, semi transparent • Made of 80% water, enzymes, carbohydrates ...
Redox Eustress: Roles for Redox-Active Metabolites in Bacterial
... organic redox-cycling compounds. Despite their high reactivity and potential to damage protein cofactors, DNA, and cellular lipids (21), some of these compounds have been shown to serve signaling functions in a diversity of organisms. Production of inorganic redox-active metabolites is more likely t ...
... organic redox-cycling compounds. Despite their high reactivity and potential to damage protein cofactors, DNA, and cellular lipids (21), some of these compounds have been shown to serve signaling functions in a diversity of organisms. Production of inorganic redox-active metabolites is more likely t ...
Epithelia and integration in sponges
... between the apical portions of larval epithelial cells in Oscarella lobularis and Corticium candelabrum (Boury-Esnault et al. 2003; Maldonado and Riesgo 2008). This junction also appears to have dense regions at the membranes, but variable staining and poor preservation of the membranes makes interp ...
... between the apical portions of larval epithelial cells in Oscarella lobularis and Corticium candelabrum (Boury-Esnault et al. 2003; Maldonado and Riesgo 2008). This junction also appears to have dense regions at the membranes, but variable staining and poor preservation of the membranes makes interp ...
BIOCHEMISTRY OF BONES
... • Osteoblasts are mono-nuclear cells; synthesize most of proteins found in bone as well as various growth factors & cytokines. ...
... • Osteoblasts are mono-nuclear cells; synthesize most of proteins found in bone as well as various growth factors & cytokines. ...
Plant Cell Wall Proteins: A Large Body of Data, but What about
... It is difficult to obtain a high coverage of the complete set of proteins present in cell walls because of the lack of surrounding membrane which can result in the loss of CWPs during the isolation procedure [66]. CWPs can have little or no interactions with cell wall components and thus move freely ...
... It is difficult to obtain a high coverage of the complete set of proteins present in cell walls because of the lack of surrounding membrane which can result in the loss of CWPs during the isolation procedure [66]. CWPs can have little or no interactions with cell wall components and thus move freely ...
Lateral inhibition and the development of the sensory bristles of the
... then adopt the secondary, epidermal fate, by a mechanism known as lateral inhibition. This presumably involves the production of a signal by the dominant cell and the reception of this signal by the remaining members of the group. A failure of this signalling mechanism would lead to all cells of the ...
... then adopt the secondary, epidermal fate, by a mechanism known as lateral inhibition. This presumably involves the production of a signal by the dominant cell and the reception of this signal by the remaining members of the group. A failure of this signalling mechanism would lead to all cells of the ...
Document
... (10) Like many other agents that affect neuron firing, adenosine must first bind to specific receptors on neuronal membranes. There are at least two classes of these receptors, which have been designated A1 and A2. Snyder et al propose that caffeine, which is struc(15) turally similar to adenosine, ...
... (10) Like many other agents that affect neuron firing, adenosine must first bind to specific receptors on neuronal membranes. There are at least two classes of these receptors, which have been designated A1 and A2. Snyder et al propose that caffeine, which is struc(15) turally similar to adenosine, ...
Chaotic expression dynamics implies pluripotency: when theory and
... Representing the cellular state involves a huge number of variables, including global gene expression, concentrations of various proteins and metabolites, and epigenetic factors such as DNA methylation. As depicted in Figure 1, the cellular state at a particular point in time is represented by a poi ...
... Representing the cellular state involves a huge number of variables, including global gene expression, concentrations of various proteins and metabolites, and epigenetic factors such as DNA methylation. As depicted in Figure 1, the cellular state at a particular point in time is represented by a poi ...
Lipids of the Plant Plasma Membrane
... Abstract The plasma membrane (PM) is arguably the most diverse membrane of the plant cell. Furthermore, the protein and lipid composition of the PM varies with cell type, developmental stage, and environment. Physical properties of lipids and associate proteins allow the formation of a barrier that ...
... Abstract The plasma membrane (PM) is arguably the most diverse membrane of the plant cell. Furthermore, the protein and lipid composition of the PM varies with cell type, developmental stage, and environment. Physical properties of lipids and associate proteins allow the formation of a barrier that ...
Myosin binding proteins - Journal of Cell Science
... the A-bands of myofibrils (Gilbert et al., 1996). However, in that study it was not certain if this information was encoded by the last four or by the last three C-terminal motifs. In addition, the motifs of MyBP-H that interact with the in vivo thick filament, and those essential for its accurate l ...
... the A-bands of myofibrils (Gilbert et al., 1996). However, in that study it was not certain if this information was encoded by the last four or by the last three C-terminal motifs. In addition, the motifs of MyBP-H that interact with the in vivo thick filament, and those essential for its accurate l ...
chapt 4
... Some are transported to other membrane structures. Some are transported to the plasma membrane. Some vesicles become lysosomes. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Some are transported to other membrane structures. Some are transported to the plasma membrane. Some vesicles become lysosomes. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
- Wiley Online Library
... Ecm11 protein is sumoylated and its level is significantly elevated during meiosis The level of Ecm11 protein during the process of meiosis was determined using Western blot analysis. Ecm11 was epitope-tagged with three HA and located with anti-HA for Western blot analysis (anti-Ecm11 antibodies are ...
... Ecm11 protein is sumoylated and its level is significantly elevated during meiosis The level of Ecm11 protein during the process of meiosis was determined using Western blot analysis. Ecm11 was epitope-tagged with three HA and located with anti-HA for Western blot analysis (anti-Ecm11 antibodies are ...
Endocytosis Via Caveolae
... While clathrin-mediated endocytosis constitutes the main pathway for internalization of extracellular ligands and plasma membrane components in most cell types, it has been recognized for some time that alternative, parallel uptake mechanisms also exist. These ‘clathrin-independent pathways’ have be ...
... While clathrin-mediated endocytosis constitutes the main pathway for internalization of extracellular ligands and plasma membrane components in most cell types, it has been recognized for some time that alternative, parallel uptake mechanisms also exist. These ‘clathrin-independent pathways’ have be ...
Myosin-Powered Membrane Compartment Drives Cytoplasmic
... How molecules and large macromolecular complexes are properly distributed and positioned is one of the central problems of cell biology. In relatively small prokaryotic cells, which lack endomembrane compartments, diffusion modulated by the cell’s metabolic status is a major mechanism at work for tr ...
... How molecules and large macromolecular complexes are properly distributed and positioned is one of the central problems of cell biology. In relatively small prokaryotic cells, which lack endomembrane compartments, diffusion modulated by the cell’s metabolic status is a major mechanism at work for tr ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.