Serial killers: ordering caspase activation events in apoptosis
... caspases and neutralizing their activity.3,4 A different strategy is utilized by another class of inhibitor ± the pseudocaspases ± which have evolved by gene duplication events but have lost enzymatic activity. These pseudocaspases can integrate into caspase activation complexes (e.g. c-FLIP compete ...
... caspases and neutralizing their activity.3,4 A different strategy is utilized by another class of inhibitor ± the pseudocaspases ± which have evolved by gene duplication events but have lost enzymatic activity. These pseudocaspases can integrate into caspase activation complexes (e.g. c-FLIP compete ...
Gene Section EP300 (E1A binding protein p300) Atlas of Genetics and Cytogenetics
... functions during differentiation; there is embryonic lethality of mice nullizygous for p300 (with defects in neurulation and heart development), and as well of mice double heterozygous for p300 and CBP, underlining their essential and associated role. ...
... functions during differentiation; there is embryonic lethality of mice nullizygous for p300 (with defects in neurulation and heart development), and as well of mice double heterozygous for p300 and CBP, underlining their essential and associated role. ...
Cell cycle exit during terminal erythroid differentiation is associated
... Cell differentiation imparts unique identity through a coordinated tissue-specific gene expression program. This program is tightly coordinated with cell cycle exit. Commitment to cell division is regulated by a family of G1 cyclin-dependent protein kinases (CDKs) (reviewed in Morgan1 and Pavletich2 ...
... Cell differentiation imparts unique identity through a coordinated tissue-specific gene expression program. This program is tightly coordinated with cell cycle exit. Commitment to cell division is regulated by a family of G1 cyclin-dependent protein kinases (CDKs) (reviewed in Morgan1 and Pavletich2 ...
the resting membrane potential
... • Let us try to further understand how the generation and existence of the resting membrane potential across the plasma membrane of cells with its slight excess of negative charge on the inside of the cell. To do this, we must grasp the following four facts. • 1. There is a difference in the concen ...
... • Let us try to further understand how the generation and existence of the resting membrane potential across the plasma membrane of cells with its slight excess of negative charge on the inside of the cell. To do this, we must grasp the following four facts. • 1. There is a difference in the concen ...
Representation of Acoustic Communication Signals
... Figure 1. Stimulus design and preprocessing. A, Sound-pressure wave of the calling song from a Ch. biguttulus male, characterized by a pronounced amplitude modulation of a broad-band carrier in the 5– 40 kHz range. The song itself is composed of many repetitions of a basic pattern, termed syllable, ...
... Figure 1. Stimulus design and preprocessing. A, Sound-pressure wave of the calling song from a Ch. biguttulus male, characterized by a pronounced amplitude modulation of a broad-band carrier in the 5– 40 kHz range. The song itself is composed of many repetitions of a basic pattern, termed syllable, ...
nerve pathways and reflex siphon withdrawal in the surf clam
... somata of efferent neurons having large fibres to the siphons occur in specific identifiable regions, the pallial integrating centres. Axons of individual cells in these regions are distributed to one or (rarely) two of the three main branches of the posterior pallial nerves on the side of origin; t ...
... somata of efferent neurons having large fibres to the siphons occur in specific identifiable regions, the pallial integrating centres. Axons of individual cells in these regions are distributed to one or (rarely) two of the three main branches of the posterior pallial nerves on the side of origin; t ...
polyribosomes
... merely to specify the sequence of sub units in one chain. In most RNA mole cules the bases are stacked on top of one another more or less like a pile of pen nies. Since the bases have a thickness of 3.4 angstrom units, the messenger RNA strand for the hemoglobin polypeptide chains should have a m ...
... merely to specify the sequence of sub units in one chain. In most RNA mole cules the bases are stacked on top of one another more or less like a pile of pen nies. Since the bases have a thickness of 3.4 angstrom units, the messenger RNA strand for the hemoglobin polypeptide chains should have a m ...
Molecular dynamics simulation studies of lipid bilayer
... main biological functions of membranes involve the maintenance of the cell integrity, control of interactions between the cell and its environment, separation of intracellular compartments, and receiving and transducing signals necessary for the cell functioning. As was elegantly shown by Gorter & G ...
... main biological functions of membranes involve the maintenance of the cell integrity, control of interactions between the cell and its environment, separation of intracellular compartments, and receiving and transducing signals necessary for the cell functioning. As was elegantly shown by Gorter & G ...
Nomenclature of the ARID family of DNA
... Fig. 3. Alignment of the mouse, dog, and human ARID domains. The alignment was created from translation of reported mouse (Mus musculus) and human (Homo sapiens) cDNA sequences, as well as from predicted ARID-containing gene sequences available from the dog (Canis familiaris) genome. In each of thes ...
... Fig. 3. Alignment of the mouse, dog, and human ARID domains. The alignment was created from translation of reported mouse (Mus musculus) and human (Homo sapiens) cDNA sequences, as well as from predicted ARID-containing gene sequences available from the dog (Canis familiaris) genome. In each of thes ...
Nuclear -Tubulin during Acentriolar Plant Mitosis
... Neither the molecular mechanism by which plant microtubules nucleate in the cytoplasm nor the organization of plant mitotic spindles, which lack centrosomes, is well understood. Here, using immunolocalization and cell fractionation techniques, we provide evidence that ␥-tubulin, a universal componen ...
... Neither the molecular mechanism by which plant microtubules nucleate in the cytoplasm nor the organization of plant mitotic spindles, which lack centrosomes, is well understood. Here, using immunolocalization and cell fractionation techniques, we provide evidence that ␥-tubulin, a universal componen ...
2.3 Carbon-Based Molecules
... • What atoms must be removed from monomers to make polymers? What is this process called? • 2 Hydrogens 1 Oxygen Dehydration Synthesis ...
... • What atoms must be removed from monomers to make polymers? What is this process called? • 2 Hydrogens 1 Oxygen Dehydration Synthesis ...
Lecture 15: Processing of viral pre-mRNA
... Lecture 16: Processing of viral pre-mRNA BSCI437 Flint et al., Chapter 10 ...
... Lecture 16: Processing of viral pre-mRNA BSCI437 Flint et al., Chapter 10 ...
Nervous System
... 2.1 Classify neurons as afferent, efferent, or interneurons. • classification based on function: – sensory or afferent neuron: - conducts nerve impulses from the body to the brain or spinal cord. - endings of its dendrite may be modified to become nerve receptors. - usually unipolar in structure. – ...
... 2.1 Classify neurons as afferent, efferent, or interneurons. • classification based on function: – sensory or afferent neuron: - conducts nerve impulses from the body to the brain or spinal cord. - endings of its dendrite may be modified to become nerve receptors. - usually unipolar in structure. – ...
Mechanisms Shaping the Membranes of Cellular Organelles
... mid surface [bilayer-coupling mechanism (Sheetz & Singer 1974)]. In agreement with these predictions, it has been found experimentally that high mole fractions of some lipids can ...
... mid surface [bilayer-coupling mechanism (Sheetz & Singer 1974)]. In agreement with these predictions, it has been found experimentally that high mole fractions of some lipids can ...
A táplálékfelvétel, a só- és vízháztartás neuroanatómiája
... - the effects of leptin on appetite and energy balance are mediated by hypothalamic neurons: basal hypothalamic lesions prevent leptin action in the brain - brain microvessels bind and internalize leptin. Leptin may gain access to neurons by receptor mediated transcytosis - leptin receptors (Ob-Rb) ...
... - the effects of leptin on appetite and energy balance are mediated by hypothalamic neurons: basal hypothalamic lesions prevent leptin action in the brain - brain microvessels bind and internalize leptin. Leptin may gain access to neurons by receptor mediated transcytosis - leptin receptors (Ob-Rb) ...
Exosome-Depleted FBS Using Beckman Coulter Centrifugation:
... Chad Schwartz, Ph. D. Beckman Coulter Life Sciences, Indianapolis, IN 46268 Exosomes are small microvesicles, derived from the late endosome, most often described in the literature to be less than 120 nm, released by all cell types, and proven to be involved in cancer metastasis1-3. Exosome characte ...
... Chad Schwartz, Ph. D. Beckman Coulter Life Sciences, Indianapolis, IN 46268 Exosomes are small microvesicles, derived from the late endosome, most often described in the literature to be less than 120 nm, released by all cell types, and proven to be involved in cancer metastasis1-3. Exosome characte ...
TIBS review article by Killian & Heijne
... side chains in KALP23 ‘snorkel’ and extend upwards towards the aqueous phase, their positively charged NH3 group can reach a position approximately 3.4 Å further away from the bilayer center than the indole NH of the Trp side chains in WALP21. This corresponds well with the difference between the po ...
... side chains in KALP23 ‘snorkel’ and extend upwards towards the aqueous phase, their positively charged NH3 group can reach a position approximately 3.4 Å further away from the bilayer center than the indole NH of the Trp side chains in WALP21. This corresponds well with the difference between the po ...
Anti-PYRUVATE KINASE (Rabbit Muscle) (GOAT) Antibody
... (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and ...
... (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and ...
From molecular activities and processes to biological function
... Figure 1. This also illustrates the flexibility of our description, as classes can be readily made more general or more specific in order to represent information on different types of biological processes, which may not necessarily be at the molecular level. It should be realised that the informati ...
... Figure 1. This also illustrates the flexibility of our description, as classes can be readily made more general or more specific in order to represent information on different types of biological processes, which may not necessarily be at the molecular level. It should be realised that the informati ...
PDF - Oxford Academic
... et al., 2007; Miskolczi et al., 2007). Microarray analysis showed constitutive expression of the Arabidopsis RBR1 gene during cell cycle progression in synchronized cells (de Almeida et al., 2009). Studies on the mammalian cell division cycle have revealed that pRb proteins act as ‘pocket domain’ pr ...
... et al., 2007; Miskolczi et al., 2007). Microarray analysis showed constitutive expression of the Arabidopsis RBR1 gene during cell cycle progression in synchronized cells (de Almeida et al., 2009). Studies on the mammalian cell division cycle have revealed that pRb proteins act as ‘pocket domain’ pr ...
Ubiquitination and sumoylation of the HTLV-2 κB activity: a
... encompassing the four C-terminal amino acids responsible for the binding to several PDZ domain-containing proteins [16-18]. In addition, some HTLV-2 subtypes express shorter versions of Tax-2 (namely Tax-2A and Tax-2CG) which, contrary to Tax-2B, do not functionally inactivate p53 [10,19]. Recent st ...
... encompassing the four C-terminal amino acids responsible for the binding to several PDZ domain-containing proteins [16-18]. In addition, some HTLV-2 subtypes express shorter versions of Tax-2 (namely Tax-2A and Tax-2CG) which, contrary to Tax-2B, do not functionally inactivate p53 [10,19]. Recent st ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... Diabetes is a multifactorial disorder of the pancreas, in which the pancreas fails to perform its function to produce insulin hormone properly in the body. It involves multiple disorders like hyperglycemia, glycosuria, abnormal metabolism of lipids, carbohydrates and proteins [1,2]. There by affecti ...
... Diabetes is a multifactorial disorder of the pancreas, in which the pancreas fails to perform its function to produce insulin hormone properly in the body. It involves multiple disorders like hyperglycemia, glycosuria, abnormal metabolism of lipids, carbohydrates and proteins [1,2]. There by affecti ...
article in press - Biochemistry
... the known differences). However, all of the known AMPK complexes are activated both by phosphorylation by an upstream kinase and allosterically by AMP. Phosphorylation of a threonine residue within the activation loop of the asubunit (T172) is required for kinase activity (Hawley et al., 1996; Stein ...
... the known differences). However, all of the known AMPK complexes are activated both by phosphorylation by an upstream kinase and allosterically by AMP. Phosphorylation of a threonine residue within the activation loop of the asubunit (T172) is required for kinase activity (Hawley et al., 1996; Stein ...
7-2 Eukaryotic Cell Structure
... Endoplasmic Reticulum Eukaryotic cells contain an internal membrane system called the endoplasmic reticulum, or ER. The endoplasmic reticulum is where lipid components of the cell membrane are assembled, along with proteins and other materials that are exported from the cell. Copyright Pearson Prent ...
... Endoplasmic Reticulum Eukaryotic cells contain an internal membrane system called the endoplasmic reticulum, or ER. The endoplasmic reticulum is where lipid components of the cell membrane are assembled, along with proteins and other materials that are exported from the cell. Copyright Pearson Prent ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.