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Root-knot nematodes manipulate plant cell functions during a
Root-knot nematodes manipulate plant cell functions during a

... implicated in feeding cell formation. AtCEL1 has been shown to be upregulated in developing giant cells (Mitchum et al., 2004). All members of the class A and class B expansin superfamily regulated upon Meloidogyne infestation have been shown to be activated in A. thaliana (Jammes et al., 2005). LeE ...
MS Word preprint
MS Word preprint

... There is an emerging picture of the inside of mitochondria as a highly ordered structure where individual enzymes are associated into functional units by compartmentation to outer membrane, inner membrane, cristal membrane, intermembrane or matrix space. Recent evidence supports an organization of p ...
5-Aminoimidazole-4-Carboxamide Riboside Mimics the
5-Aminoimidazole-4-Carboxamide Riboside Mimics the

... achieved by the other agents are unknown. However, the generation of PIP3 is not required by any of these agents, whereas the activation of p38 MAP kinase is not required for the action of hydrogen peroxide or sodium arsenite (23). In addition, all of these agents exert their effects independently o ...
reviews - Lab. Biodados UFMG
reviews - Lab. Biodados UFMG

... re-enter a quiescent state and can undergo enforced differentiation32–34. Deletion of Rb in the skin results in a decrease in the number of label-retaining, slowly cycling cells in the stem cell compartment35. These data raise two different possibilities: first, RB-mutant skin stem cells might die o ...
Isolation, Characterization, and Expression of cDNAs Encoding
Isolation, Characterization, and Expression of cDNAs Encoding

... AND O-GLYCAN structures are increasingly being found to contribute to biological recognition events during development, oncogenic transformation, and cell adhesion (3, 10, 11, 37, 38, 40) . The enzymes involved in the maturation of cell surface and intracellular N-glycans are found in the endoplasmi ...
Characterization of the Plasmid-Encoded Arsenic Salts Resistance
Characterization of the Plasmid-Encoded Arsenic Salts Resistance

... ArsR of R773, the pair of Cys-32 and Cys-34 is conserved and an important component of the metal recognition site. However, there was only one Cys-33 in the putative metalbinding domain of ArsR from K. oxytoca. Therefore, we presumed that Ser-31 and Cys-33 could be the ligands to arsenate, which res ...
Small Signaling Peptides in Arabidopsis Development
Small Signaling Peptides in Arabidopsis Development

... Benfey, 2010; Van Norman et al., 2011). Most prominently, directional transport of the phytohormone auxin from one cell to the other provides cues for patterning and development (Vanneste and Friml, 2009; Grunewald and Friml, 2010). However, signaling through direct symplastic transport of transcrip ...
Molecular encounters at microtubule ends in the plant cell cortex
Molecular encounters at microtubule ends in the plant cell cortex

... In this model, 6–7 g-TuSC subcomplexes (each composed of 2 g-tubulins, one GCP2 and one GCP3) are held together in a helicoidal conformation by other GCP subunits that form the cap structure of the g-TuRC. Arrangement of g-tubulin molecules in the complex provides a template for initiating a/b-tubul ...
Applications of recombinant DNA technology in
Applications of recombinant DNA technology in

... The DNA present in all eukaryotic cells is tightly associated to histones, forming chromatin. Moreover, the packaging of eukaryotic DNA into chromatin has important ramifications in terms of its availability to serve as a template for transcription. Thus, chromatin structure is a critical aspect of ...
Andrei Fagarasanu Department of Cell Biology Supervisor: Dr
Andrei Fagarasanu Department of Cell Biology Supervisor: Dr

... peroxisome transport, and were surprised that Inp2p levels increased until every peroxisome in the mother cell carried the receptor. This suggests that once enough peroxisomes have accumulated in the bud of wild-type cells, a signal is relayed to the mother cell resulting in Inp2p degradation and a ...
Biochem10 - Amit Kessel Ph.D
Biochem10 - Amit Kessel Ph.D

... E. glucokinase. 24. Thyroid hormone receptors A. are histone proteins localized in the chromatin of target cells. B. are intrinsic non-histone chromosomal proteins. C. initially bind triiodothyronine in the cytoplasm and after undergoing a conformational change translocate to the nucleus. D. are enz ...
The RNA-binding protein HuR regulates protein nuclear import
The RNA-binding protein HuR regulates protein nuclear import

... transfection of importin β1 (Fig. S3A). Cells were also transfected with a luciferase reporter driven by an RAR response element (RARE) and a vector encoding β-galactosidase, which served as transfection control. Cells were treated with RA (1 μM, overnight) and luciferase activity measured and norm ...
reviews
reviews

... carboxy‑terminal ligand by the subtilisin‑like proprotein convertases furin (also known as PCSK3) and SPC4 (also known as PCSK6 and PACE4). The nodal proprotein functions as a partial agonist by binding to its receptors in a co‑receptor (epidermal growth factor (EGF)–CFC)‑ independent manner. The ex ...
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel

... involved in DNA replication and gene expression (Lamond and Earnshaw, 1998). The most prominent nuclear subcompartment is the nucleolus, which is the site of transcription and processing of ribosomal RNAs (rRNAs), and their assembly into ribosomal subunits before export to the cytoplasm (Olsen et al ...
The retinal pigment epithelium: a versatile partner in vision
The retinal pigment epithelium: a versatile partner in vision

... retinoid isom erase (Barry et al., 1989), a m em brane-bound enzym e that converts the ester to 1 l-c« -retin o l (Bernstein et al., 1987). This retinoid isom er is bound by yet another intracellular binding protein nam ed cellular retinal binding protein (CRA LBP, Futterm an et al., 1977). It prese ...
Package `signalHsmm`
Package `signalHsmm`

... Using hidden semi-Markov models as a probabilistic framework, signalHsmm is new, highly accurate signal peptide predictor for eukaryotic proteins. Details Secretory signal peptides are short (20-30 residues) N-terminal amino acid sequences tagging among others tag among others hormons, immune system ...
Profibrillin conversion by proprotein convertases
Profibrillin conversion by proprotein convertases

... encoding a mini-profibrillin-1 protein with the unique amino and carboxyl termini of profibrillin-1, and a central region of the fibrillin-1 protein encoded by exons 23-44 (Fig. 1). The central region of fibrillin was chosen because we have inferred from the clustering of mutations in neonatal Marfa ...
A single mutation in the core domain of the lac repressor reduces
A single mutation in the core domain of the lac repressor reduces

... Background: The lac operon provides cells with the ability to switch from glucose to lactose metabolism precisely when necessary. This metabolic switch is mediated by the lac repressor (LacI), which in the absence of lactose binds to the operator DNA sequence to inhibit transcription. Allosteric rea ...
BIOCHEMICAL ADAPTATION
BIOCHEMICAL ADAPTATION

... 2. Temperature alters the strength of the weak bonds that are critical to the conformation of macromolecules and to the conformational changes that occur during ligand binding and catalysis in enzymes. A decrease in temperature increases the stability of hydrogen bonds, van der Waals interactions, a ...
Plant Cell Growth and Elongation
Plant Cell Growth and Elongation

... isoxaben results in disorganized microtubules in elongating cells. The multinet growth hypothesis was developed to explain how cellulose microfibrils in the cotton fibre are deposited in a shallow helical orientation net transverse to the elongation axis but are displaced longitudinally as elongation ...
Bacteriophage lambda surface display of a bacterial biotin acceptor
Bacteriophage lambda surface display of a bacterial biotin acceptor

... for protein biotin ligases in other organisms. On the basis of our results, however, it is highly unlikely that a 13-amino acid peptide derived from Kp_OAD is able to e¡ect biotinylation in E. coli. The presented data clearly demonstrate that bacteriophage lambda surface display is a powerful techni ...
Plasma membrane
Plasma membrane

... This is an overview of the role of mitochondria in energy production. Mitochondria absorb short carbon chains (such as pyruvate) and oxygen and generate carbon dioxide and ATP. © 2012 Pearson Education, Inc. ...
5 x buffer (50TB 25 7 - American Journal of Physiology
5 x buffer (50TB 25 7 - American Journal of Physiology

... muscle as a source of the enriched GLUT-4 donor membrane fraction. We tested whether cytosolic protein fractions prepared from other tissue sources (liver, brain, blood plasma) than rat skeletal muscle could induce in vitro GLUT-4 transfer. We found that human blood plasma and to a lesser extent bra ...
Isolation and Purification of RP2-L, a Nuclear Protein Fraction of the
Isolation and Purification of RP2-L, a Nuclear Protein Fraction of the

... slow-moving bands of the original starting mate rial. These data along with the data indicated be low with regard to the N-terminal amino acids indicate that purification of RP2-L has been achieved but further procedures are required for ...
SCUBE3 (Signal Peptide-CUB-EGF Domain
SCUBE3 (Signal Peptide-CUB-EGF Domain

... organized in a modular fashion and share at least five protein domains: 1) an NH2-terminal signal peptide sequence, 2) nine copies of EGF-like repeats, 3) a spacer region, 4) three cysteinerich motifs, and 5) one CUB domain at the COOH terminus. Scube gene expression is overlapping and/or complement ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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