Anopheles gambiae Drosophila melanogaster Bo Lindberg
... Malaria is a disease of poverty and continues to plague a great part of the world’s population. An increased understanding of the interactions between the vector mosquito, the malaria parasite, and also the mosquito gut microbiota are pivotal for the development of novel measures against the disease ...
... Malaria is a disease of poverty and continues to plague a great part of the world’s population. An increased understanding of the interactions between the vector mosquito, the malaria parasite, and also the mosquito gut microbiota are pivotal for the development of novel measures against the disease ...
the scf ubiquitin ligase: insights into a molecular machine
... (LRR)), the domain is an arc-shaped α–β-repeat structure that is also found in many protein-binding contexts, including the extracellular-binding domain of certain surface receptors11,12. In most cases, FBLs also seem to involve substrate phosphorylation for their interaction, but this does not seem ...
... (LRR)), the domain is an arc-shaped α–β-repeat structure that is also found in many protein-binding contexts, including the extracellular-binding domain of certain surface receptors11,12. In most cases, FBLs also seem to involve substrate phosphorylation for their interaction, but this does not seem ...
A decrease in cellular energy status stimulates PERK
... protein; DMEM, Dulbecco’s modified Eagle’s medium; dsRNA, double-stranded RNA; eIF2, eukaryotic initiation factor 2; ER, endoplasmic reticulum; FCS, foetal calf serum; GADD34, growth-arrest and DNA-damage-inducible protein 34; GCN2, general control non-derepressible 2; HRI, haem-regulated eIF2α kina ...
... protein; DMEM, Dulbecco’s modified Eagle’s medium; dsRNA, double-stranded RNA; eIF2, eukaryotic initiation factor 2; ER, endoplasmic reticulum; FCS, foetal calf serum; GADD34, growth-arrest and DNA-damage-inducible protein 34; GCN2, general control non-derepressible 2; HRI, haem-regulated eIF2α kina ...
Lipid raft–associated protein sorting in exosomes
... other cells.3-7 Exosomes correspond to internal vesicles of multivesicular bodies (MVBs) and are released in the extracellular medium upon fusion of MVBs with the plasma membrane. Exosome secretion was shown to be responsible for the loss of transferrin receptors (TfRs) during reticulocyte maturatio ...
... other cells.3-7 Exosomes correspond to internal vesicles of multivesicular bodies (MVBs) and are released in the extracellular medium upon fusion of MVBs with the plasma membrane. Exosome secretion was shown to be responsible for the loss of transferrin receptors (TfRs) during reticulocyte maturatio ...
Control of the Plant Cell Cycle by Developmental
... Plant morphogenesis relies on cell proliferation and differentiation strictly controlled in space and time. As in other eukaryotes, progression through the plant cell cycle is governed by cyclin-dependent kinases (CDKs) that associate with their activator proteins called cyclins (CYCs), and the acti ...
... Plant morphogenesis relies on cell proliferation and differentiation strictly controlled in space and time. As in other eukaryotes, progression through the plant cell cycle is governed by cyclin-dependent kinases (CDKs) that associate with their activator proteins called cyclins (CYCs), and the acti ...
nitric oxide as a mediator of aba signalling in stomatal guard cells
... Water shortage is likely to one of the major global environmental stresses of the twenty-first century. Reduced water availability is a major limitation to crop yield, as cell expansion requires the cell pressure potential to be sufficiently high to permit irreversible cell wall stretching. Thus, ce ...
... Water shortage is likely to one of the major global environmental stresses of the twenty-first century. Reduced water availability is a major limitation to crop yield, as cell expansion requires the cell pressure potential to be sufficiently high to permit irreversible cell wall stretching. Thus, ce ...
NUCLEAR AND CYTOPLASMIC STAINING
... The cytoskeleton (also CSK) is a cellular "scaffolding" or "skeleton" contained within the cytoplasm and is made out of protein. The cytoskeleton is present in all cells; it was once thought to be uni ...
... The cytoskeleton (also CSK) is a cellular "scaffolding" or "skeleton" contained within the cytoplasm and is made out of protein. The cytoskeleton is present in all cells; it was once thought to be uni ...
Augmin Plays a Critical Role in Organizing the
... complex has been isolated from human cells for its role in centrosome-independent MT generation in spindles and chromosome segregation (Lawo et al., 2009; Uehara et al., 2009; Hutchins et al., 2010). Augmin and the g-tubulin complex appear to interact via the WD40 repeat protein NEDD1/GCP-WD (Zhu et ...
... complex has been isolated from human cells for its role in centrosome-independent MT generation in spindles and chromosome segregation (Lawo et al., 2009; Uehara et al., 2009; Hutchins et al., 2010). Augmin and the g-tubulin complex appear to interact via the WD40 repeat protein NEDD1/GCP-WD (Zhu et ...
A Superfamily of S Locus-Related Sequences in
... in primary sequence and gene structure, it is possible that these genes also function in cell-cell signaling at some as yet unknown stage of the plant life cycle. To understand the organization and evolution of the S gene family and eventually define the biological function of individual members, it ...
... in primary sequence and gene structure, it is possible that these genes also function in cell-cell signaling at some as yet unknown stage of the plant life cycle. To understand the organization and evolution of the S gene family and eventually define the biological function of individual members, it ...
Directions: Choose the BEST answer from among those given.
... 19. Anabolic reactions are the biosynthetic biochemical reactions or pathways in which larger molecules are made from smaller? a) true b) false 20. A-kinase (cyclic-AMP-dependent protein kinase) is an enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic-AMP. This ...
... 19. Anabolic reactions are the biosynthetic biochemical reactions or pathways in which larger molecules are made from smaller? a) true b) false 20. A-kinase (cyclic-AMP-dependent protein kinase) is an enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic-AMP. This ...
mbe.oxfordjournals.org - Oxford Academic
... Tagging of S6 Fragments Lacking the 3 Authentic NLSs with the Heterologous SV40 NLS To produce the SV40 NLS–tagged S6 constructs, the oligonucleotides T-Ag1 and T-Ag2 (table 2) were hybridized giving rise to a double-stranded DNA fragment with a NotI site at the 5# end and an EcoRI site at the 3# en ...
... Tagging of S6 Fragments Lacking the 3 Authentic NLSs with the Heterologous SV40 NLS To produce the SV40 NLS–tagged S6 constructs, the oligonucleotides T-Ag1 and T-Ag2 (table 2) were hybridized giving rise to a double-stranded DNA fragment with a NotI site at the 5# end and an EcoRI site at the 3# en ...
Functional studies of the BTB domain in the Drosophila GAGA and
... vitro transcription of the Drosophila engrailed and Ultrabithorax promoters (27,28). Subsequent studies have shown that GAGA has a general and significant role in transcription regulation. Its single Cys2–His2 zinc finger can mediate high affinity specific binding to a consensus sequence containing ...
... vitro transcription of the Drosophila engrailed and Ultrabithorax promoters (27,28). Subsequent studies have shown that GAGA has a general and significant role in transcription regulation. Its single Cys2–His2 zinc finger can mediate high affinity specific binding to a consensus sequence containing ...
C. elegans daf-6 Encodes a Patched-Related Protein
... conferred some ability to take up dye from the environment (Figures 2A and 2B). A 2968 bp full-length daf-6 cDNA clone was obtained from Yuji Kohara (DNA Data Bank of Japan). The daf-6 intron/exon organization was determined by comparing the cDNA and genomic sequences (Figure 2A). Conceptual transla ...
... conferred some ability to take up dye from the environment (Figures 2A and 2B). A 2968 bp full-length daf-6 cDNA clone was obtained from Yuji Kohara (DNA Data Bank of Japan). The daf-6 intron/exon organization was determined by comparing the cDNA and genomic sequences (Figure 2A). Conceptual transla ...
Sensitizing B Cells for TLR2 Ligands Cell
... recognized by the nucleotide oligomerization domain (Nod) receptors meso-D-glutamyl-meso-diaminopimelic acid (Nod1) and muramyl dipeptide (Nod2). These cytoplasmic pattern recognition receptors are involved in the innate immune recognition of bacteria (26 –31). Additionally, most peptidoglycan prepa ...
... recognized by the nucleotide oligomerization domain (Nod) receptors meso-D-glutamyl-meso-diaminopimelic acid (Nod1) and muramyl dipeptide (Nod2). These cytoplasmic pattern recognition receptors are involved in the innate immune recognition of bacteria (26 –31). Additionally, most peptidoglycan prepa ...
Cellular Automata Course outline
... resigned to not explain how these elements are made of real things, particularly how these elements are made up of elementary particles or even molecules (...) we will simply assume that elementary particles with certain properties exist. The question we hope to answer, or at least consider is: what ...
... resigned to not explain how these elements are made of real things, particularly how these elements are made up of elementary particles or even molecules (...) we will simply assume that elementary particles with certain properties exist. The question we hope to answer, or at least consider is: what ...
Improved insights into protein thermal stability: from the
... but rather that it is more stable compared to the other residue-residue interactions. For all three temperatures, this interaction appears as destabilizing in the distance window between about 3 and 6 Å, even if at higher temperature (red curve) the destabilization effect is reduced with respect to ...
... but rather that it is more stable compared to the other residue-residue interactions. For all three temperatures, this interaction appears as destabilizing in the distance window between about 3 and 6 Å, even if at higher temperature (red curve) the destabilization effect is reduced with respect to ...
Targeting of Proteins to Endoplasmic Reticulum
... Upon exiting the nucleus, the assembly of a large ribonucleoprotein particle or granule occurs as a result of the interaction of RNA-binding proteins with the targeted RNA, changing its conformation and thus triggering the binding of additional proteins. This RNA transport particle may contain multi ...
... Upon exiting the nucleus, the assembly of a large ribonucleoprotein particle or granule occurs as a result of the interaction of RNA-binding proteins with the targeted RNA, changing its conformation and thus triggering the binding of additional proteins. This RNA transport particle may contain multi ...
The Golgi-Localized Arabidopsis Endomembrane
... export signals, such as the diacidic DXE motif and dibasic motif, have been identified in different classes of transmembrane proteins in plant cells (Hanton et al., 2005; Yuasa et al., 2005; Mikosch et al., 2006; Schoberer et al., 2009; Zelazny et al., 2009). In addition, the dilysine motif present i ...
... export signals, such as the diacidic DXE motif and dibasic motif, have been identified in different classes of transmembrane proteins in plant cells (Hanton et al., 2005; Yuasa et al., 2005; Mikosch et al., 2006; Schoberer et al., 2009; Zelazny et al., 2009). In addition, the dilysine motif present i ...
Tsui, S, Dai, T, Warren, ST and Yen, P: Association of the mouse infertility factor DAZL1 with actively translating polyribosomes. Biology of Reproduction 62:1655-1660 (2000).
... mainly through the RRM domain. The results for DAZ are less clear-cut. Deletion of RRM in either DAZ-R1 or DAZR2 diminished, but did not abolish, the RNA-binding ability. Similarly, deletion of seven of the nine DAZ repeats (in DAZ-Z1) or the C-terminal portion including the entire DAZ repeat region ...
... mainly through the RRM domain. The results for DAZ are less clear-cut. Deletion of RRM in either DAZ-R1 or DAZR2 diminished, but did not abolish, the RNA-binding ability. Similarly, deletion of seven of the nine DAZ repeats (in DAZ-Z1) or the C-terminal portion including the entire DAZ repeat region ...
Manipulation of the host translation initiation complex eIF4F by DNA
... Eukaryotic mRNAs are capped at their 5 -end by a 7-methylGTP and polyadenylated at their 3 -end, both of which function during translation initiation. Ribosome recruitment to the 5 -end is facilitated by eIF4F, which consists of a small cap-binding protein, eIF4E, an ATP-dependent RNA helicase, e ...
... Eukaryotic mRNAs are capped at their 5 -end by a 7-methylGTP and polyadenylated at their 3 -end, both of which function during translation initiation. Ribosome recruitment to the 5 -end is facilitated by eIF4F, which consists of a small cap-binding protein, eIF4E, an ATP-dependent RNA helicase, e ...
The TEA Transcription Factor Tec1 Links TOR and MAPK Pathways
... current view that the TORC1 and Ras/PKA pathways act in parallel in the control of cell division (Rohde et al. 2008). With respect to controlling cellular development, the Ras/ PKA pathway is known to regulate adhesive and filamentous growth via the catalytic subunit Tpk2, which targets the transcrip ...
... current view that the TORC1 and Ras/PKA pathways act in parallel in the control of cell division (Rohde et al. 2008). With respect to controlling cellular development, the Ras/ PKA pathway is known to regulate adhesive and filamentous growth via the catalytic subunit Tpk2, which targets the transcrip ...
AnSc 5311 Ruminant Nutrition Microbial Fermentation of
... ATP yield seems to be 1 mole per 3 moles of lactate because the acyldehydrogenase does not seem to be linked to phosphorylation ...
... ATP yield seems to be 1 mole per 3 moles of lactate because the acyldehydrogenase does not seem to be linked to phosphorylation ...
Life Substances - Ms. Rago's Class Website
... Differences in functional groups affects function of the compound A ...
... Differences in functional groups affects function of the compound A ...
Reduction of the number of new cells reaching olfactory bulbs
... antagonist (WAY100635) did not change numbers of BrdU labeled cells found two months later in the SVZ/ RMS (Fig. 2A). All groups of opossums had almost the same numbers of these cells. However, numbers of BrdU-labeled cells placed in the OB were markedly higher in opossums treated with agonists of t ...
... antagonist (WAY100635) did not change numbers of BrdU labeled cells found two months later in the SVZ/ RMS (Fig. 2A). All groups of opossums had almost the same numbers of these cells. However, numbers of BrdU-labeled cells placed in the OB were markedly higher in opossums treated with agonists of t ...
SNARE Complex Proteins in Rat Mast Cells Phosphorylation of
... Activation of several chemoattractant receptors results in leukocyte degranulation. However, it is unclear whether chemoattractant-induced degranulation uses the same mechanisms as those triggered by FcRI cross-linking. Leukocyte chemoattractant receptors functionally couple to heterotrimeric G pro ...
... Activation of several chemoattractant receptors results in leukocyte degranulation. However, it is unclear whether chemoattractant-induced degranulation uses the same mechanisms as those triggered by FcRI cross-linking. Leukocyte chemoattractant receptors functionally couple to heterotrimeric G pro ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.