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Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly
Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly

... dead-end products of assembly and still progress into mature 30S subunits that assemble into 70S ribosomes, however, maturation occurs at a much slower pace in the absence of YjeQ or RimM. Quantitative mass spectrometry analysis (qMS) revealed these immature 30S subunits when purified under non-diss ...
RabGDI controls axonal midline crossing by regulating Robo1
RabGDI controls axonal midline crossing by regulating Robo1

... Robo expression [16-19]. In vertebrates, positive regulators of midline crossing were first identified [20]. Both in vivo and in vitro interactions of Axonin-1/TAG-1/ Contactin-2 and NrCAM were shown to mask a repellent activity of the floor plate [21,22]. The repellent activity was later attributed ...
Lignin biosynthesis in Norway spruce: from a model system to the tree
Lignin biosynthesis in Norway spruce: from a model system to the tree

... vascular plants. It enables water conduction through the stem, supports the upright growth habit and protects against invading pathogens. In addition, lignin hinders the utilisation of the cellulosic cell walls of plants in pulp and paper industry and as forage. Lignin precursors are synthesised in ...
Nitrate regulation of metabolism and growth Mark Stitt
Nitrate regulation of metabolism and growth Mark Stitt

... senescence [1,2]. These far-reaching changes underline the important role played by the signalling mechanisms that regulate metabolism and development in response to the availability of nitrogen. Signals might be derived from nitrate itself, from metabolites formed during nitrate assimilation, or, m ...
Bactericidal/Permeability-Increasing Protein Release in Whole
Bactericidal/Permeability-Increasing Protein Release in Whole

... BPI, at concentrations as low as 10 pg/mL. Since PMNL express two receptors for TNF-a, a 55-kDa (TNFRss ) and a 75kDa (TNFR75 ) receptor, which are both able to mediate part of TNF-a activities [27, 29], we analyzed which receptor was involved in TNF-a-induced BPI release. To this end, whole blood w ...
Cell-intrinsic drivers of dendrite morphogenesis
Cell-intrinsic drivers of dendrite morphogenesis

... Box 1) have vastly improved our understanding of dendrite development (Scott and Luo, 2001; Grueber and Jan, 2004). The development of new approaches for studying dendrite morphogenesis (see Box 2) has led to the view that axons and dendrites work in concert to define neuronal connectivity. A key co ...
Axon Physiology - Physiological Reviews
Axon Physiology - Physiological Reviews

... main axon is involved in the secure propagation of action potentials, but it is also able to integrate fluctuations in membrane potential originating from the somatodendritic region to modulate neurotransmitter release (5, 291, 489). Finally, the axon terminal that is principally devoted to excitati ...
Cytoskeleton and Root Hair Growth
Cytoskeleton and Root Hair Growth

... the bulge is devoid of microtubules when the root hair swelling is ready to initiate tip growth (Baluska et al., 2000). At the same time, actin filaments at the future bulge site become arranged parallel to the long axis of the cell (Baluska et al., 2000). G-actin and profilin also accumulate at the ...
Microsoft Word
Microsoft Word

... A panel of thirteen anti-TPO mAbs produced against native human TPO, as it mentioned above, was used for the pioneering studies on the immunodominant regions located on the TPO molecule surface [5, 8]. Antibodies numbered 2, 9, 47, and 60 reacted with epitopes in domain A, mAbs 15, 18, 59, and 64 r ...
Company presentation continous
Company presentation continous

... •Recombinant DNA technology allows the engineer antibodies •It is possible to produce complete antibodies in cell ...
Stressed out: the skeletal muscle ryanodine receptor as a target of
Stressed out: the skeletal muscle ryanodine receptor as a target of

... pathways and physiological regulators of RyR1 channel function, see ref. 12. Muscle stress RyR1 activity is modulated by stable posttranslational modifications, such as phosphorylation, nitrosylation, and oxidation, all of which can be downstream effects of stress-dependent signaling pathways. Repet ...
Lectins, as non-self-recognition factors, in crustaceans
Lectins, as non-self-recognition factors, in crustaceans

... self-glycoproteins ŽThiel and Reid, 1989.. This observation is related to the equatorial orientation of the C3–OH and C4–OH groups of the sugar moiety ŽWeis and Drickamer, 1996., a configuration represented in the hexoses N-acetylglucosamine ŽGlcNAc., glucose and fucose as well as mannose. Combinati ...
Chitin and Chitosan in Fungi - Wiley-VCH
Chitin and Chitosan in Fungi - Wiley-VCH

... readers who are not familiar with these aminoglucans should consult also Chapter 15, this volume (Chitin and Chitosan from Animal Sources). ...
Polarization of the endomembrane system is an early event in fucoid
Polarization of the endomembrane system is an early event in fucoid

... that establish cell polarity and determine the site of tip growth. A common feature of polarity establishment is targeting endocytosis and exocytosis (secretion) to localized cortical domains. We have investigated the spatiotemporal development of endomembrane asymmetry in photopolarizing zygotes, a ...
Euglena gracilis ascorbate peroxidase forms an intramolecular
Euglena gracilis ascorbate peroxidase forms an intramolecular

... APX-N and APX-C domains with ascorbate and H2 O2 were almost the same as that of the native enzyme. However, the substrate specificity of the mature FL-APX and the native enzyme was different from that of APX-N and APX-C. The mature FL-APX, but not the truncated forms, could reduce alkyl hydroperoxi ...
Identification and analysis of new phloem proteins from
Identification and analysis of new phloem proteins from

... organic acids, sugars and several proteins that are taken up or produced by the roots and subsequently distributed to aerial parts of the plant (Lopez-Millan et al., 2000; Buhtz et al., 2004). This translocation system exploits the physical forces produced by water potential differences in the soil- ...
Altered morphology produced by ftsZ expression in
Altered morphology produced by ftsZ expression in

... pBR322 derivative containing the kan gene from Tn5 and used as source of kan 2?9 kb XhoI–SacI fragment (ftsZ) subcloned in pBSK+ Mobilizable E. coli/C. glutamicum bifunctional plasmid containing kan and cat Bifunctional E. coli/C. glutamicum promoter-probe vector with bla and hyg genes as selective ...
Supplementary materials - Stanford Artificial Intelligence Laboratory
Supplementary materials - Stanford Artificial Intelligence Laboratory

... module in which they appeared, but did not require global acyclicity because the real regulatory network is not acyclic. (a) Learning the regulatory program: Given a set of modules, we learned the regulatory association for each module by using the candidate expression (e-) and genotype (g-) regula ...
Transcription factor Sp3 is silenced through - IMT
Transcription factor Sp3 is silenced through - IMT

... according to Kingsley and Winoto, 1992) that could act as a target for SUMO modi®cation (Melchior, 2000). SUMO-modi®ed proteins have an ~20 kDa higher apparent molecular weight compared with unmodi®ed proteins. However, previously we did not observe such high molecular weight species in immunoblots ...
Lateral root initiation is a probabilistic event whose frequency is set
Lateral root initiation is a probabilistic event whose frequency is set

... regular, periodic production of pre-branch sites, which are described as groups of cells that have the capacity to form LRP (Moreno-Risueno et al., 2010). These sites are defined by oscillating waves of gene expression. Evidence for the model is drawn from microarray experiments showing that when th ...
Vesicles versus Tubes: is ER-Golgi Transport in
Vesicles versus Tubes: is ER-Golgi Transport in

... sciences. Indeed, and with few exceptions (e.g. Ito et al., 2014) there are few reviews ...
Glycogen Synthase Sensitivity to Insulin and Glucose-6
Glycogen Synthase Sensitivity to Insulin and Glucose-6

... glycogen synthase. Incorporation of 1.2 mol/subunit of phosphate into rabbit skeletal muscle glycogen synthase catalyzed by GSK-3 caused a 15-fold increase in M0.5 for glucose-6-phosphate. However, phosphorylation to a similar extent with either cyclic AMP–dependent protein kinase or phosphorylase k ...
Biological effects of Extracellular fibrinogen binding protein (Efb) in
Biological effects of Extracellular fibrinogen binding protein (Efb) in

... Staphylococcus aureus is a leading cause of human and animal infection. The increasing incidence of antibiotic resistance among strains has complicated treatment of these infections. In order to develop new treatment strategies, it is important to identify and characterise bacterial factors that con ...
View/Open - Minerva Access
View/Open - Minerva Access

... charged lipid membranes, further development is worthwhile pursuing. Reversibility of the membrane-bound state: pre-incubation method The reversibility of the lipid-bound state can also be assessed in a competitive environment. When Mac1 was pre-incubated with dye-free POPC vesicles and then combine ...
Cell cycle checkpoints in Caenorhabditis elegans
Cell cycle checkpoints in Caenorhabditis elegans

... IR: Ionizing Radiation NEBD: Nuclear Envelope Breakdown ssDNA: single stranded DNA UV: Ultra Violet light ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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